About
77
Publications
3,655
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
464
Citations
Introduction
Skills and Expertise
Publications
Publications (77)
Background:
In 2006, the HPV (Human papillomavirus) 6/11/16/18 quadrivalent vaccine was approved by the European Medicines Agency and obtained its marketing authorization in both girls and boys. Currently, the French guidelines recommend and refund vaccination of girls aged 11 to 14 with a catch-up program for females from 15 to 19 years old.
Dis...
Introduction
La prévalence du diabète gestationnel (DG) est en augmentation partout dans le monde, parallèlement à celle de l’obésité chez la femme en âge de procréer. Le DG est associé à une morbi-mortalité materno-fœtale à court terme mais également à plus long terme. L’objectif de notre étude était d’évaluer si la mise en place de règles hygiéno...
Objective
To compare the early feto-maternal morbidity after assisted vaginal delivery using forceps versus spatulas.
Patients and methods
It is a retrospective comparative study conducted in a third level maternity carrying on cephalic instrumental non premature deliveries by forceps or spatulas, on singleton pregnancies. Forty assisted vaginal d...
Apesar de que en la actualidad las salpingitis son menos frecuentes, se trata de afecciones graves en razón de las secuelas pélvicas irreversibles que provocan. Un mejor conocimiento de su nueva presentación clínica permitirá reducir la incidencia de la esterilidad.
A rape is a traumatizing circumstance for the victim. This aggression often has, regrettably, immediate repercussions, and then medium and long-term ones. Its complications are psychological, but also sometimes somatic, like pregnancy. Through an international literature review, and the study of the national legislation, we will summarize the main...
A rape is a traumatizing circumstance for the victim. This aggression often has, regrettably, immediate repercussions, and then medium and long-term ones. Its complications are psychological, but also sometimes somatic, like pregnancy. Through an international literature review, and the study of the national legislation, we will summarize the main...
Objective
. This study was performed to evaluate the efficacy and safety of a prebiotic treatment in the balance recovery of the vaginal flora in subjects previously treated for bacterial vaginosis (BV).
Study Design
. A randomized trial was carried out on 42 subjects with an active prebiotic group compared to a placebo group. The main evaluation c...
In countries where induced abortions are legal and medically supervised, the frequency of post-abortion infections is low and maternal death is infrequent. Nevertheless, short and long term consequences of post-abortion infections must be addressed. Sexually transmitted pathogens are frequently in cause here. Risk factors include in particular youn...
Post-partum endometritis are frequent and account for the fifth cause of maternal death. This disease is preventable and effective treatments are available. Streptococcus agalactiae is the primary pathogen implicated. The clinical diagnosis is usually easy and involves pelvic pain, fever and abnormal lochia. Whenever antibiotic treatment provides n...
Las cervicitis corresponden a infecciones, fundamentalmente bacterianas, del conducto endocervical. Son frecuentes y están causadas, fundamentalmente, por un germen de transmisión sexual (Chlamydia trachomatis [CT], Neisseria gonorrhoeae [NG], Mycoplasma genitalium [MG]) o por un patógeno de la flora vaginal. Con frecuencia, las cervicitis son asin...
Although considerable progresses were made in the field of medically assisted procreation, surgery keeps its place in the therapeutic armamentarium of female infertility. Indeed, its results are very interesting, both in its tubal, myometrial and endometriosis indications. Laparotomy is the first step in the development of any surgical technique. L...
OBJECTIVE: To compare the early feto-maternal morbidity after assisted vaginal delivery using forceps versus spatulas. PATIENTS AND METHODS: It is a retrospective comparative study conducted in a third level maternity carrying on cephalic instrumental non premature deliveries by forceps or spatulas, on singleton pregnancies. Forty assisted vaginal...
In case of severe post-partum haemorrhage, resuscitation and surgical techniques are complementary and should be adjusted to both the aetiology and severity of haemorrhage. In the most severe cases, hysterectomy should not be delayed. In all women with stable haemodynamic status, conservative surgical approaches should be applied. Indications, feas...
In cases of serious bleeding postpartum, resuscitation and surgical techniques are complementary and should be adapted to both the etiology and severity of bleeding. In extremely severe cases, the performance of a hysterectomy should not be delayed. For women with stable hemodynamic status, so-called "conservative" surgical techniques can instead b...
To evaluate the efficacy and safety of moxifloxacin versus levofloxacin plus metronidazole in uncomplicated pelvic inflammatory disease (uPID) in Asia.
Prospective, randomised, double-blind, double-dummy, parallel-group study.
Multicentre, multinational study in the inpatient and/or outpatient setting.
Women (aged ≥18 years) with uPID (defined as P...
The management of pelvic inflammatory disease (PID) has significantly changed during the last two decades. Moreover, some recent bacterial findings have led to recent changes in this management.
Most cases of PID are mild-to-moderate uncomplicated forms that can be treated as outpatients. Apart from Chlamydia trachomatis and Neisseria gonorrhoeae,...
Uncomplicated pelvic inflammatory disease (PID) is a common disease caused by numerous pathogens: sexually transmitted infections (such as Chlamydia trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium), anaerobes, and other organisms from the vaginal flora. It is currently treated by oral route and most present protocols recommend ofloxaci...
Las infecciones genitales altas se producen esencialmente por la contaminación del aparato genital por vía ascendente. Los agentes patógenos pueden transmitirse sexualmente (Chlamydia trachomatis, Neisseria gonorrhoeae) o venir de la flora vaginal (enterobacterias, anaerobios, etc.). La forma no complicada se presenta a menudo con una sintomatologí...
TO THE EDITORS: We read with great interest the article by Greenberg et al. 1 As noted by the authors and because of the growing number of cesarean deliveries, the frequency of abnormally invasive placentation is increasing. 2 Despite improved prenatal diagnosis (ultrasound scans and magnetic resonance imaging), the management of placentas accreta...
This study was designed to assess the ability of an ultrasound-guided radiofrequency (RF)-driven procedure to induce complete and irreversible cord occlusion using a 90 days fetal sheep model.
Twenty 90 days gestation sheep underwent general anesthesia. The first ten fetuses were exposed under hysterotomy, and RF electrode was inserted visually in...
Pelvic inflammatory disease (PID) remains one of the most important consequences of sexually transmitted infections (STIs) resulting in severe morbidity and acting as the economic justification for STI screening programmes. Early and appropriate therapy has the potential to significantly reduce the long-term complications of PID, and these evidence...
Resumé: L'herpès génital (HG) est une pathologie fréquente qui continue de progresser dans tous les pays. Il est dû aux Herpesviridae
HSV-1 et HSV-2 qui se transmettent essentiellement par voie sexuelle. La plupart des patients infectés ignorent qu'ils le
sont parce qu'ils sont asymptomatiques (20%) ou parce que le diagnostic d'HG n'a pas été établ...
Infections due to bacteria, virus or parasites are frequent during pregnancy and can have severe consequences. Moreover, the vaginal carriage of commensal bacteria or dramatic changes in the equilibrium of the vaginal flora can induce complications and cause fetal contaminations. With the help of the guidelines set up by the French Agency of Accred...
Infections due to bacteria, virus or parasites are frequent during pregnancy and can have severe consequences. Moreover, the vaginal carriage of commensal bacteria or dramatic changes in the equilibrium of the vaginal flora can induce complications and cause fetal contaminations. With the help of the guidelines set up by the French Agency of Accred...
Infection génitale haute (IGH) dont la prévalence est mal connue en France. Le principal facteur de risque est l’âge jeune. Les pathogènes sont transmis par voie sexuelle: Chlamydiæ trachomatis, gonocoque, flore génitale commensale. La symptomatologie clinique est atténuée. Absence de parallélisme entre l’intensité des signes cliniques et l’atteint...
The mycoplasmas frequently isolated in genital tract, and potentially pathogenic, are M. hominis, U. urealyticum and M. genitalium. M. hominis and U. urealyticum are very frequent in the vaginal tract and they can be, according to circumstances, either commensal or pathogenic. M. hominis and/or U. urealyticum, have been considered as responsible fo...
The mycoplasmas frequently isolated in genital tract, and potentially pathogenic, are M. hominis, U. urealyticum and M. genitalium. M. hominis and U. urealyticum are very frequent in the vaginal tract and they can be, according to circumstances, either commensal or pathogenic. M. hominis and/or U. urealyticum, have been considered as responsible fo...
Genital herpes is a frequent chronic, sexually-transmitted disease among adults. Besides its physical consequences that largely depend on the frequency and intensity of recurrences, genital herpes frequently induces a psychological morbidity. This paper discusses the instruments of measure that can be used in the evaluation of health-related qualit...
Genital herpes is a frequent chronic, sexually-transmitted disease among adults. Besides its physical consequences that largely depend on the frequency and intensity of recurrences, genital herpes frequently induces a psychological morbidity. This paper discusses the instruments of measure that can be used in the evaluation of health-related qualit...
Herpes is a viral infection which increases, specifically genital herpes. The aim of this survey was to assess the perception of herpes in the general population and in patients with herpes in France using a self-administered questionnaire. A total of 10,000 persons answered the questionnaire among which 128 patients presented herpes. This study sh...
Herpes is a viral infection which increases, specifically genital herpes. The aim of this survey was to assess the perception of herpes in the general population and in patients with herpes in France using a self-administered questionnaire. A total of 10 000 persons answered the questionnaire among which 128 patients presented herpes. This study sh...
Les maladies sexuellement transmissibles (MST) constituent un fléau mondial de santé publique. Les principales MST de l'adolescente sont : les chlamydioses, les infections à Papillomavirus, l'herpès génital, la trichomoniase urogénitale, les mycoplasmes, la gonococcie, la syphilis, les hépatites virales, le cytomégalovirus, la vaginose bactérienne....
Endometritis are upper genital tract infections. They are part of the Pelvic Inflammatory Diseases and are often difficult to differentiate from salpingitis. C. trachomatis, a sexually transmitted micro-organism, is a major pathogen of the genital tract. Most of the time, the upper genital tract infections are polymicrobial and C. trachomatis can b...
In the 300,000 inhabitant city-area of Nancy (France), admission of women victims of sexual violence follows a special procedure. That has been jointly set by the Justice Department, Police and Emergency Rooms of both the Maternite Régionale and the University General Hospital. Nevertheless, we have recently conclude the management and follow-up of...
In the 300.000 inhabitant city-area of Nancy (France), admission of women victims of sexual violence follows a special procedure. That has been jointly set by the Justice Department Police and Emergency Rooms of both the Maternite Regionale and the University General Hospital. Nevertheless, we have recently conclude the management and follow-up of...
Nowadays, most patients with uncomplicated acute salpingitis undergo ambulatory treatment. The choice of medications must take features of PID into account: they are mult-microbial infections and a prolonged follow-up is necessary in order to decrease the risk of sequellae. To fulfil these goals, combination of antibiotics are prescribed that are a...
Classify antibiotics according to their individual activity so as to identify those suitable for empiric therapy.
We studied bacterial strains isolated from patients with urethritis (n = 189) and upper genital tract infections (n = 163) between June 1994 and February 1995 in 3 hospital and 4 community laboratories. Upper genital tract infections we...
To evaluate the efficacy and safety of ofloxacin+coamoxiclav versus doxycycline-coamoxiclav in the treatment of chlamydial pelvic infections.
An open, comparative, randomised, monocentric study.
A hundred and eighteen patients (85 endometritis and 33 salpingitis) were included. Clinical, laparoscopic and bacteriological assessments were performed b...
Acute pelvic pain is a common syndrome in women and is an emergency. Management requires rapid diagnostic evaluation to enable immediate treatment. Blood tests (beta-HCG assay, etc.), bacteriological studies and pelvic ultrasonography may be required. Gynecological problems are the commonest etiology: ectopic pregnancy, miscarriage, PID. The possib...
A 56-year-old woman with long-lasting fever of unknown origin was diagnosed as having a giant-cell arteritis of the genital tract with no evidence of temporal arteritis. Diagnosis relied on pathological examination, which showed a segmental panarteritis of ovaries, myometrium, endometrium and uterus cervix. Corticosteroid therapy led to clinical cu...
Pregnant Wistar rats were given by subcutaneous route 1 of 3 different adrenoreceptor blockers, 2 of them mainly beta-blockers. P5 and P7 group received propranolol (5 and 7 mg/kg respectively), L10 and L20 groups received labetalol (10 and 20 mg/kg) and B5 group received betaxolol (5 mg/kg). Drugs were given daily from the 7th to the 16th day of g...
There is an increased risk of cancer (mainly breast cancer) in patients with Cowden disease. Little is known of the etiopathogenic mechanisms of this condition, but immunologic abnormalities may be evoked. A young patient with Cowden disease was submitted for gynecologic examination and immunologic investigations. Although no neoplastic disorder ha...
One case of uremic-haemolytic syndrome associated with an ectopic pregnancy is reported. The main signs are, from the clinical standpoint, a diffuse haemorrhagic syndrome and, from the biological standpoint, a haemolytic anemia, renal failure and thrombopenia. This pathology, exceptionally associated with an early pregnancy, required an intensive r...
The prognosis of cancers is conditioned by tumoral extension. We report a case of a squamous carcinoma of the vulva where pathological examination had been at fault. An immunohistological study performed with monoclonal antibodies revealed a lymph node micro-metastasis. This case emphasizes the importance of estimating the tumoral extension by simu...
