Publications (69) View all
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Article: Use of ionic liquids as stationary phases in hyphenated gas chromatography techniques.
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ABSTRACT: In the past decades a consistent number of ionic liquids have been specifically synthesized and evaluated as stationary phase in gas chromatography. Ionic liquid, also defined as "molten salts", are a class of organic non-molecular solvents liquid at room temperature (RTILs) that satisfy most of the requirements of a GC stationary phase, among which a high viscosity, the possibility to tune the selectivity (by changing the cation-anion combination) and a high thermal stability. The choice of the proper stationary phase plays a key role in the improvement/optimization of a GC method, and although the use of IL as stationary phases is still not well-established, the general interest in their applications has greatly increased, thanks to their particular properties. The present contribution provides an overview on recent evaluations and applications of IL stationary phases, focusing in particular on the use of these novel tools in hyphenated GC-based techniques.Journal of chromatography. A 05/2012; 1255:130-44. · 4.19 Impact Factor -
Article: Modulators for comprehensive two-dimensional gas chromatography
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ABSTRACT: Cited By (since 1996): 10, Export Date: 15 January 2013, Source: Scopus, CODEN: TTAED, doi: 10.1016/j.trac.2011.06.010, Language of Original Document: English, Correspondence Address: Mondello, L.; Dipartimento Farmaco-chimico, Facoltà di Farmacia, Università di Messina, Viale Annunziata, 98168 - Messina, Italy; email: lmondello@unime.it, References: Pursch, M., Sun, K., Winniford, B., Cortes, H., Weber, A., McCabe, T., Luong, J., (2002) Anal. Bioanal. Chem., 373, p. 367;TrAC Trends in Analytical Chemistry 01/2011; 30(9):1437-1461. · 6.27 Impact Factor -
Article: Thorough evaluation of the validity of conventional enantio-gas chromatography in the analysis of volatile chiral compounds in mandarin essential oil: A comparative investigation with multidimensional gas chromatography.
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ABSTRACT: The present research is focused on the determination of the enantiomeric distribution of chiral compounds, contained in mandarin essential oils, by means of conventional chiral gas chromatography with flame ionization detection (enantio-GC-FID); the results attained were compared with those derived from heart-cutting multidimensional GC-mass spectrometry (MDGC/MS), to evaluate the reliability of the monodimensional technique as a tool for quality control. The Deans-switch MDGC system was equipped with two GC ovens, which were connected via a heated transfer line, a flame ionization detector (FID1) in the first dimension and a quadrupole MS as second-dimension detector. The a priori knowledge of potential co-elutions concerning target compounds (an enantiomer and an interfering compound), when using enantio-GC-FID, could enable the use of corrected enantiomer excess values. Correction factors could be calculated through a preliminary GC-FID analysis (using an apolar column), considering the peak areas of the known interferences. The method used for the calculation of a so-called "coelution correction factor" is described, along with some examples.Journal of chromatography. A 10/2009; 1217(7):1101-5. · 4.19 Impact Factor -
Article: Conventional and fast gas chromatography analysis of biodiesel blends using an ionic liquid stationary phase.
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ABSTRACT: The present research is focused on the GC-FID determination of fatty acid methyl esters (FAMEs) in diesel blends, by means of an ionic liquid stationary phase, characterized by a dicationic 1,9-di(3-vinyl-imidazolium)nonane bis(trifluoromethyl)sulfonylimidate structure (SLB-IL100). The high polarity of the ionic liquid stationary phase allowed the separation of the FAMEs, from the less-retained hydrocarbons, thus avoiding the requirement of a hydrocarbon LC pre-separation. The results derived from the analyses of a soybean FAMEs B20 sample, carried out on an SLB-IL100 conventional column (30 m x 0.25 mm i.d. x 0.20 mm d(f)), were compared with those attained on a polyethylene glycol column, of equivalent dimensions. Conventional and fast GC methods, for the analysis of FAMEs in diesel blends, were developed on an SLB-IL100 30 m x 0.25 mm i.d. x 0.20 microm d(f) and on an SLB-IL100 12 m x 0.10 mm i.d. x 0.08 microm d(f) column, respectively. The optimized IL methods were subjected to validation: retention time and peak area intra-day precision (n=5) were good, with CV % values lower than 0.08% and 4.9%, respectively. With regards to the quantitation of FAMEs in biodiesel blends, a five points calibration curve was constructed, using C(17:0) as internal standard.Journal of chromatography. A 10/2009; 1216(51):8992-7. · 4.19 Impact Factor -
Article: Optimized use of a 50 microm internal diameter secondary column in a comprehensive two-dimensional gas chromatography system.
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ABSTRACT: The focus of the present research is directed toward the development of a comprehensive two-dimensional gas chromatography (GC x GC) method, characterized by a greatly increased separation power, if compared with GC x GC approaches using classical column combinations. The analytical objective was achieved by using a 0.05 mm internal diameter (i.d.) capillary as second dimension, a split-flow approach reported in previous research (Tranchida, P. Q., Casilli, A., Dugo, P., Dugo, G. and Mondello, L. Anal. Chem. 2007, 79, 2266-2275), and a twin-oven GC x GC instrument. The column combination employed was an orthogonal one: an apolar 30 m x 0.25 mm i.d. column was linked, by means of a Y-union, to a flame ionization detector (FID)-connected high-resolution 1 m x 0.05 mm i.d. polar one and to a 0.20 m x 0.05 mm i.d. uncoated capillary segment; the latter was connected to a manually operated split valve, located on top of the second GC. As previously shown, the generation of optimum gas linear velocities in both dimensions can be attained by splitting gas flows at the outlet of the first dimension (Tranchida, P. Q., Casilli, A., Dugo, P., Dugo, G. and Mondello, L. Anal. Chem. 2007, 79, 2266-2275). An optimized GC x GC method was developed and exploited for the analysis of a complex petrochemical sample. The satisfactory results attained were directly compared with those observed using the same instrumentation, equipped with what can be defined as a classical GC x GC split-flow column set: the same primary column was connected to an FID-linked 1 m x 0.10 mm i.d. polar one and to a 0.30 m x 0.10 mm i.d. uncoated capillary. It will be herein illustrated that there is still room for significant progress in the GC x GC field.Analytical Chemistry 09/2009; 81(20):8529-37. · 5.86 Impact Factor
