Skills (7)
Research experience
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Jan 2012–
presentTeaching: Beni Suef University
Beni Suef University · Department of Pharmaceutics and Industrial Pharmacy.Egypt · Banī SuwayfExperimental demonstration of : 1- Dosage formulations; 2 -Physical Pharmacy; 3- Pharmacokinetics; 4- Industrial Pharmacy. -
Nov 2010–
Nov 2011Research: Buccal Delivery of anti emetics
School of Pharmacy, University of London · Pharmaceutics · School of Pharmacy, University of LondonProf. Jonathan Hadgraft (Skin Group) · London -
Mar 2005–
Jun 2009Teaching: Demonstrator
Cairo University · Department of PharmaceuticsEgypt · Bani SuwayfExperimental demonstration of : 1- Dosage formulations; 2 -Physical Pharmacy; 3- Pharmacokinetics; 4- Industrial Pharmacy.
Education
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Apr 2005–
May 2009Cairo University
Pharmaceutics · MSc.Egypt · Cairo
Other
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LanguagesEnglish and Arabic
Publications (1) View all
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Article: Preparation and characterization of mosapride citrate inclusion complexes with natural and synthetic cyclodextrins.
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ABSTRACT: The aim of this work was to investigate the inclusion complexes between mosapride citrate and SBE(7)β-CD in comparison with the natural β-CD to enhance its bioavailability by improving the solubility and dissolution rate. The complexation efficiency value of SBE(7)β-CD was higher than that for β-CD. Solid binary systems of mosapride citrate with CDs were prepared by physical mixing, kneading and freeze-drying techniques at molar ratio of 1:1(drug:CD). Physicochemical characterization of the prepared systems was studied using X-ray diffractometry, differential scanning calorimetry, Fourier-transform infrared spectroscopy and scanning electron microscopy (SEM). Amorphous drug was detectable to large extent in inclusion complexes prepared using the freeze-drying technique. From the dissolution study of different inclusion complexes in simulated saliva solution (pH 6.8), we could concluded that irrespective of the preparation technique, the systems prepared using SBE(7)β-CD showed better performance than the corresponding ones prepared using β-CD. In addition, the freeze-drying technique showed superior dissolution enhancement than other methods especially when combined with the SBE(7)β-CD.Pharmaceutical Development and Technology 12/2011; · 1.36 Impact Factor
About
My research is focused on the drug delivery through the skin and buccal mucosa as biological barriers through the use of different formulations like hydrogels and films. Also to understand the route of transport of the actives through these biological barriers.
