Research: Synthesis of impurities and Impurity profiling of ZonisamiddeRoland Institute of Pharmaceutical Sciences · Pharmaceutical Chemistry · Roland Institute of Pharmaceutical SciencesDr. B.V.V. Ravi Kumar Sir, Nargesh Kumar Keshar · BerhampurSynthesis of Zonisamide impurities HPLC method development
Biju Patnaik University of TechnologyM. PharmIndia · Berhampur
Regional Drugs Testing LaboratoryPreliminary knowledge on Instrumental and Microbiology method of Analysis of DrugsIndia · Guwahati
Article: New Stability Indicating RP-HPLC Method for the Estimation of Cefpirome Sulphate in Bulk and Pharmaceutical Dosage Forms.[show abstract] [hide abstract]
ABSTRACT: A simple stability indicating reversed-phase HPLC method was developed and subsequently validated for estimation of Cefpirome sulphate (CPS) present in pharmaceutical dosage forms. The proposed RP-HPLC method utilizes a LiChroCART-Lichrosphere100, C18 RP column (250 mm × 4mm × 5 μm) in an isocratic separation mode with mobile phase consisting of methanol and water in the proportion of 50:50 % (v/v), at a flow rate 1ml/min, and the effluent was monitored at 270 nm. The retention time of CPS was 2.733 min and its formulation was exposed to acidic, alkaline, photolytic, thermal and oxidative stress conditions, and the stressed samples were analyzed by the proposed method. The described method was linear over a range of 0.5-200μg/ml. The percentage recovery was 99.46. F-test and t-test at 95% confidence level were used to check the intermediate precision data obtained under different experimental setups; the calculated value was found to be less than the critical value.Scientia Pharmaceutica 01/2011; 79(4):899-907.
Article: In vitro antioxidant activity and total phenolic content of chloroform bark extract of Mimusops ElengiIndian Journal of Pharmaceutical Education and Research. 01/2011; 45.
Article: Evaluation of in vitro Antioxidant Activity and Total Phenolic Content of Methanol Bark Extract of Mimusops elengiFree Radicals and Antioxidants. 01/2011; 1:62-71.
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