Nancy Babio

Publications

• 3.73

  Impact points

  Evaluation of the Safety and Efficacy of Hydroxycitric Acid or Garcinia cambogia Extracts in Humans.

  Fabiola Márquez, Nancy Babio, Mònica Bulló, J Salas-Salvadó

  Critical reviews in food science and nutrition. 07/2012; 52(7):585-94.

  Several studies have shown that Garcinia cambogia plays an important role in the regulation of endogenous lipid biosynthesis. This effect is specially attributed to (-)-hydroxycitric acid (HCA) inhibiting the enzyme ATP-dependent citrate lyase, which catalyzes the cleavage of citrate to oxaloacetate... [more] Several studies have shown that Garcinia cambogia plays an important role in the regulation of endogenous lipid biosynthesis. This effect is specially attributed to (-)-hydroxycitric acid (HCA) inhibiting the enzyme ATP-dependent citrate lyase, which catalyzes the cleavage of citrate to oxaloacetate and acetyl-CoA. Although several studies have found that the administration of G. cambogia extracts is associated with body weight and fat loss in both experimental animals and humans, we should be cautious when interpreting the results as other randomized, placebo-controlled clinical trials have not reported the same outcomes. Furthermore, most studies in humans have been conducted on small samples and mainly in the short term. None of them have shown whether these effects persist beyond 12 weeks of intervention. Therefore, there is still little evidence to support the potential effectiveness and long-term benefits of G. cambogia extracts. With regard to toxicity and safety, it is important to note that except in rare cases, studies conducted in experimental animals have not reported increased mortality or significant toxicity. Furthermore, at the doses usually administered, no differences have been reported in terms of side effects or adverse events (those studied) in humans between individuals treated with G. cambogia and controls.
• 4.29

  Impact points

  FABP4 predicts atherogenic dyslipidemia development. The PREDIMED study.

  Anna Cabré, Nancy Babio, Iolanda Lázaro, Mònica Bulló, Ana Garcia-Arellano, Lluís Masana, Jordi Salas-Salvadó

  Atherosclerosis. 02/2012;

  OBJECTIVE: Atherogenic dyslipidemia (AD), characterized by high plasma triglycerides and low HDL particles, is considered one of the main effectors of vascular damage associated with obesity, metabolic syndrome (MS) and type 2 diabetes. Adipocyte fatty acid-binding protein (FABP4) plasma concentrati... [more] OBJECTIVE: Atherogenic dyslipidemia (AD), characterized by high plasma triglycerides and low HDL particles, is considered one of the main effectors of vascular damage associated with obesity, metabolic syndrome (MS) and type 2 diabetes. Adipocyte fatty acid-binding protein (FABP4) plasma concentrations have been linked to metabolic alterations that are associated with adiposity. The aim of the present study was to prospectively analyze the predictive value of baseline FABP4 plasma concentrations for the development of AD. METHODS: In the frame of the PREDIMED study, a multicenter dietary interventional trial, we prospectively measured the baseline plasma FABP4 levels and AD incidence over a six-year follow-up period (median 4 [IQR, 3-5years]) in 578 volunteers who visited their general practitioners because of their cardiovascular risk factors. RESULTS: During follow-up, 103 participants developed AD. Baseline plasma FABP4 levels were associated with new onset AD over the follow-up period (OR 1.03 [95% IC: 1.00-1.05], p=0.020). This increased risk was observed in women but not in men. Among women, those in the highest tertile of FABP4 had a 2.54-fold increased relative risk of developing AD compared to the lowest tertile (HR 2.54 [95% CI, 1.31-4.93], p for trend=0.008). CONCLUSIONS: Elevated plasma FABP4 concentrations should be considered as a potential marker of metabolic derangement, which may predict the development of AD in women.

• Babio

  Cabré A, Babio N, Lázaro I, Bulló M, Garcia-Arellano A, Masana L, Salas-Salvadó J

  Atherosclerosis. 02/2012;

  OBJECTIVE: Atherogenic dyslipidemia (AD), characterized by high plasma triglycerides and low HDL particles, is considered one of the main effectors of vascular damage associated with obesity, metabolic syndrome (MS) and type 2 diabetes. Adipocyte fatty acid-binding protein (FABP4) plasma concentrat... [more] OBJECTIVE: Atherogenic dyslipidemia (AD), characterized by high plasma triglycerides and low HDL particles, is considered one of the main effectors of vascular damage associated with obesity, metabolic syndrome (MS) and type 2 diabetes. Adipocyte fatty acid-binding protein (FABP4) plasma concentrations have been linked to metabolic alterations that are associated with adiposity. The aim of the present study was to prospectively analyze the predictive value of baseline FABP4 plasma concentrations for the development of AD. METHODS: In the frame of the PREDIMED study, a multicenter dietary interventional trial, we prospectively measured the baseline plasma FABP4 levels and AD incidence over a six-year follow-up period (median 4 [IQR, 3-5years]) in 578 volunteers who visited their general practitioners because of their cardiovascular risk factors. RESULTS: During follow-up, 103 participants developed AD. Baseline plasma FABP4 levels were associated with new onset AD over the follow-up period (OR 1.03 [95% IC: 1.00-1.05], p=0.020). This increased risk was observed in women but not in men. Among women, those in the highest tertile of FABP4 had a 2.54-fold increased relative risk of developing AD compared to the lowest tertile (HR 2.54 [95% CI, 1.31-4.93], p for trend=0.008). CONCLUSIONS: Elevated plasma FABP4 concentrations should be considered as a potential marker of metabolic derangement, which may predict the development of AD in women.

• Reduction in the Incidence of Type 2-Diabetes with the Mediterranean Diet: Results of the PREDIMED-Reus Nutrition Intervention Randomized Trial

  Salas-Salvadó J, Bulló M, Babio N, Martínez-González MÁ, Ibarrola-Jurado N, Basora J, Estruch R, Covas MI, Corella D, Arós F, Ruiz-Gutiérrez V, Ros E, PREDIMED Study Investigators.

  Diabetes Care. 01/2011; 34(1):14-9.

  Objective - To test the effects of two Mediterranean-diet interventions versus a low-fat diet on incidence of diabetes. Research Design and Methods - Three-arm randomized trial in 418 nondiabetic subjects aged 55-80 years recruited in one center (PREDIMED-Reus, North-Eastern Spain) of the PREDIMED s... [more] Objective - To test the effects of two Mediterranean-diet interventions versus a low-fat diet on incidence of diabetes. Research Design and Methods - Three-arm randomized trial in 418 nondiabetic subjects aged 55-80 years recruited in one center (PREDIMED-Reus, North-Eastern Spain) of the PREDIMED study, a large nutrition-intervention trial for primary cardiovascular prevention in persons at high cardiovascular risk. Participants were randomized to education on a low-fat diet (control group) or one of two Mediterranean diets, supplemented with either free virgin olive oil (1 liter/week) or nuts (30 g/day). Diets were ad libitum and no advice on physical activity was given. The main outcome was diabetes incidence diagnosed by the 2009 American Diabetes Association criteria. Results - After a median follow-up of 4.0 years, diabetes incidence was 10.1% (95% confidence interval [CI], 5.1-15.1), 11.0% (5.9-16.1), and 17.9% (11.4-24.4) in the Mediterranean-diet with olive oil group, the Mediterranean-diet with nuts group, and the control group, respectively. Multivariable-adjusted hazard ratios of diabetes were 0.49 (0.25-0.97) and 0.48 (0.24-0.96) in the Mediterranean-diet groups supplemented with olive oil and nuts, respectively, compared to the control group. When pooling the two Mediterranean-diet groups compared to the control group, diabetes incidence was reduced by 52% (27-86). In all study arms, increased adherence to the Mediterranean-diet was inversely associated with diabetes incidence. Diabetes risk reduction occurred in the absence of significant changes in body weight or physical activity. Conclusion - Mediterranean diets without calorie restriction appear to be effective in the prevention of diabetes in subjects at high cardiovascular risk. Trial Registration: www.controlled-trials.com Identifier: ISRCTN35739639

• Evaluation of safety and efficacy of hydroxicitric acid or Garcinia Cambogia extracts in humans

  Márquez Fabiola, Babio Nancy, Bulló Mònica, J. Salas-Salvadó

  Critical Reviews in Food Science and Nutrition. 01/2011;

  Several studies have shown that Garcinia cambogia plays an important role in the regulation of endogenous lipid biosynthesis. This effect is specially attributed to (−)-hydroxycitric acid (HCA) inhibiting the enzyme ATP-dependent citrate lyase, which catalyses the cleavage of citrate to oxaloacetate... [more] Several studies have shown that Garcinia cambogia plays an important role in the regulation of endogenous lipid biosynthesis. This effect is specially attributed to (−)-hydroxycitric acid (HCA) inhibiting the enzyme ATP-dependent citrate lyase, which catalyses the cleavage of citrate to oxaloacetate and acetyl-CoA. Although several studies have found that the administration of G. cambogia extracts is associated with body weight and fat loss in both experimental animals and humans, we should be cautious when interpreting the results as other randomized, placebo-controlled clinical trials have not reported the same outcomes. Furthermore, most studies in humans have been conducted on small samples and mainly in the short term. None of them have shown whether these effects persist beyond 12 weeks of intervention. Therefore, there is still little evidence to support the potential effectiveness and long-term benefits of G. cambogia extracts. With regard to toxicity and safety, it is important to note that except in rare cases, studies conducted in experimental animals have not reported increased mortality or significant toxicity. Furthermore, at the doses usually administered, no differences have been reported in terms of side effects or adverse events (those studied) in humans between individuals treated with G. cambogia and controls.
• 6.72

  Impact points

  Reduction in the incidence of type 2 diabetes with the Mediterranean diet: results of the PREDIMED-Reus nutrition intervention randomized trial.

  Jordi Salas-Salvadó, Monica Bulló, Nancy Babio, Miguel Ángel Martínez-González, Núria Ibarrola-Jurado, Josep Basora, Ramon Estruch, Maria Isabel Covas, Dolores Corella, Fernando Arós, Valentina Ruiz-Gutiérrez, Emilio Ros

  Diabetes care. 10/2010; 34(1):14-9.

  To test the effects of two Mediterranean diet (MedDiet) interventions versus a low-fat diet on incidence of diabetes. This was a three-arm randomized trial in 418 nondiabetic subjects aged 55-80 years recruited in one center (PREDIMED-Reus, northeastern Spain) of the Prevención con Dieta Mediterráne... [more] To test the effects of two Mediterranean diet (MedDiet) interventions versus a low-fat diet on incidence of diabetes. This was a three-arm randomized trial in 418 nondiabetic subjects aged 55-80 years recruited in one center (PREDIMED-Reus, northeastern Spain) of the Prevención con Dieta Mediterránea [PREDIMED] study, a large nutrition intervention trial for primary cardiovascular prevention in individuals at high cardiovascular risk. Participants were randomly assigned to education on a low-fat diet (control group) or to one of two MedDiets, supplemented with either free virgin olive oil (1 liter/week) or nuts (30 g/day). Diets were ad libitum, and no advice on physical activity was given. The main outcome was diabetes incidence diagnosed by the 2009 American Diabetes Association criteria. After a median follow-up of 4.0 years, diabetes incidence was 10.1% (95% CI 5.1-15.1), 11.0% (5.9-16.1), and 17.9% (11.4-24.4) in the MedDiet with olive oil group, the MedDiet with nuts group, and the control group, respectively. Multivariable adjusted hazard ratios of diabetes were 0.49 (0.25-0.97) and 0.48 (0.24-0.96) in the MedDiet supplemented with olive oil and nuts groups, respectively, compared with the control group. When the two MedDiet groups were pooled and compared with the control group, diabetes incidence was reduced by 52% (27-86). In all study arms, increased adherence to the MedDiet was inversely associated with diabetes incidence. Diabetes risk reduction occurred in the absence of significant changes in body weight or physical activity. MedDiets without calorie restriction seem to be effective in the prevention of diabetes in subjects at high cardiovascular risk.
• 3.52

  Impact points

  Association between red meat consumption and metabolic syndrome in a Mediterranean population at high cardiovascular risk: Cross-sectional and 1-year follow-up assessment.

  N Babio, M Sorlí, M Bulló, J Basora, N Ibarrola-Jurado, J Fernández-Ballart, M A Martínez-González, L Serra-Majem, R González-Pérez, Jordi Salas-Salvadó

  Nutrition, metabolism, and cardiovascular diseases : NMCD. 09/2010;

  BACKGROUND AND AIMS: Little is known about the role that red meat and processed red meat (RM) consumption plays in the development of the metabolic syndrome (MetS). The aim was to assess the relationship between RM consumption and the prevalence or incidence of the MetS and its components in a Medit... [more] BACKGROUND AND AIMS: Little is known about the role that red meat and processed red meat (RM) consumption plays in the development of the metabolic syndrome (MetS). The aim was to assess the relationship between RM consumption and the prevalence or incidence of the MetS and its components in a Mediterranean population at high risk of cardiovascular disease. METHODS AND RESULTS: Cross-sectional analyses were carried out at baseline and at 1-year follow-up and longitudinal analysis were conducted in a cohort of individuals at high risk of cardiovascular disease from the PREDIMED study. A 137-item validated semi-quantitative food frequency questionnaire, anthropometric measurements, blood pressure, fasting plasma glucose and lipid profile were evaluated both at baseline and after 1-year follow-up. The MetS was defined in accordance with the updated ATP III criteria. Subjects in the upper quartile of RM consumption were more likely to meet the criteria for the MetS at baseline (OR, 2.3; 95% CI, 1.4-3.9; P-trend = 0.001) and after 1-year follow-up (OR, 2.2; 95% CI, 1.3-3.7; P-trend = 0.034) compared with those in the quartile of reference, even after adjusting for potential confounders. The longitudinal analyses showed that individuals in the fourth quartile of RM consumption had an increased risk of MetS (OR, 2.7; 95% CI, 1.1-6.8; P-trend = 0.009) or central obesity incidence (OR, 8.1; 95% CI, 1.4-46.0; P-trend = 0.077) at the end of the follow-up compared to the lowest quartile. CONCLUSIONS: Higher RM consumption is associated with a significantly higher prevalence and incidence of MetS and central obesity in individuals at high risk of cardiovascular disease.
• 3.44

  Impact points

  Nuts and oxidation: a systematic review.

  Patricia López-Uriarte, Mònica Bulló, Patricia Casas-Agustench, Nancy Babio, Jordi Salas-Salvadó

  Nutrition reviews. 10/2009; 67(9):497-508.

  In recent years, nuts have received special attention because of their potential role in preventing cardiovascular disease. Because nuts are very rich in total fat that can potentially be oxidized and their skins contain several antioxidants, studies have been conducted to evaluate the potential eff... [more] In recent years, nuts have received special attention because of their potential role in preventing cardiovascular disease. Because nuts are very rich in total fat that can potentially be oxidized and their skins contain several antioxidants, studies have been conducted to evaluate the potential effect of nut consumption on oxidative stress. This review evaluates the in vitro and in vivo studies conducted in animals or humans to analyze the effect of nuts on oxidation.
• 2.75

  Impact points

  Mediterranean diet and metabolic syndrome: the evidence.

  Nancy Babio, Mònica Bulló, Jordi Salas-Salvadó

  Public health nutrition. 10/2009; 12(9A):1607-17.

  BACKGROUND: The Mediterranean diet has long been related to a lower cardiovascular disease risk; however, more recent evidences also indicate that it has a favourable effect on adiposity and type 2 diabetes. DESIGN: Review of the available literature in relation to Mediterranean diet and metabolic s... [more] BACKGROUND: The Mediterranean diet has long been related to a lower cardiovascular disease risk; however, more recent evidences also indicate that it has a favourable effect on adiposity and type 2 diabetes. DESIGN: Review of the available literature in relation to Mediterranean diet and metabolic syndrome. RESULTS: Several components of Mediterranean diet patterns have been inversely related with body mass index. They are considered to be modulators of insulin resistance, can exert beneficial effects on blood pressure, improve atherogenic dyslipidemia or attenuate the inflammatory burden associated with metabolic syndrome. Furthermore, a lower prevalence of metabolic syndrome has been associated with dietary patterns rich in fruits and vegetables, nuts, olive oil, legumes and fish, moderate in alcohol and low in red meat, processed meat, refined carbohydrates and whole-fat dairy products. CONCLUSIONS: There is much evidence suggesting that the Mediterranean diet could serve as an anti-inflammatory dietary pattern, which could help to fight diseases related to chronic inflammation, including metabolic syndrome.
• 3.66

  Impact points

  Mediterranean diet and high dietary acid load associated with mixed nuts: effect on bone metabolism in elderly subjects.

  Mònica Bulló, Pilar Amigó-Correig, Fabiola Márquez-Sandoval, Nancy Babio, Miquel A Martínez-González, Ramon Estruch, Joseph Basora, Rosa Solà, Jordi Salas-Salvadó

  Journal of the American Geriatrics Society. 10/2009; 57(10):1789-98.

  OBJECTIVES: To analyze the effect of differing diet on the acid load content on bone metabolism. DESIGN: Multicentric, randomized, single-blind, parallel-group clinical trial. SETTING: Outpatient clinics. PARTICIPANTS: Two hundred thirty-eight elderly men and women aged 60 to 80 at high risk for car... [more] OBJECTIVES: To analyze the effect of differing diet on the acid load content on bone metabolism. DESIGN: Multicentric, randomized, single-blind, parallel-group clinical trial. SETTING: Outpatient clinics. PARTICIPANTS: Two hundred thirty-eight elderly men and women aged 60 to 80 at high risk for cardiovascular disease were randomly assigned to three interventional groups: a recommended low-fat diet (control diet group), a Mediterranean diet supplemented with virgin olive oil, or a Mediterranean diet supplemented with mixed nuts. MEASUREMENTS: Main outcomes were 12-month changes from baseline in bone formation and resorption markers and bone mass measured according to quantitative ultrasound scanning. RESULTS: The baseline data on the anthropometric, bone densitometry, and biochemical variables did not differ between the three groups. Dietary potential renal acid load (PRAL) and daily net endogenous acid production (NEAP) at baseline did not differ between groups. After intervention, subjects allocated to the Mediterranean diet with mixed nuts had a significant increase of PRAL and NEAP. In comparison, subjects in the Mediterranean diet with nuts group had higher parathyroid hormone (PTH) levels (2.63, 95% confidence interval (CI)=-1.01-6.35, P=.02) and a nonsignificantly higher (0.31, 95% CI=-0.13-0.74, P=.14) urine free deoxypyridoxine:creatinine ratio, a marker of bone resorption, than the control group and the Mediterranean diet with virgin olive oil group. CONCLUSION: A Mediterranean dietary pattern associated with a high dietary acid load derived from consumption of mixed nuts does not seem to have a much greater effect on bone metabolism biomarkers, with the exception of PTH levels, than a Mediterranean diet without mixed nuts or a control diet in elderly subjects.
• 3.52

  Impact points

  Adherence to the Mediterranean diet and risk of metabolic syndrome and its components.

  N Babio, M Bulló, J Basora, M A Martínez-González, J Fernández-Ballart, F Márquez-Sandoval, C Molina, J Salas-Salvadó

  Nutrition, metabolism, and cardiovascular diseases : NMCD. 02/2009;

  BACKGROUND AND AIMS: The role of diet in the aetiology of metabolic syndrome (MetS) is not well understood. The aim of the present study was to evaluate the relationship between adherence to the Mediterranean diet (MedDiet) and MetS. METHODS AND RESULTS: A cross-sectional study was conducted with 80... [more] BACKGROUND AND AIMS: The role of diet in the aetiology of metabolic syndrome (MetS) is not well understood. The aim of the present study was to evaluate the relationship between adherence to the Mediterranean diet (MedDiet) and MetS. METHODS AND RESULTS: A cross-sectional study was conducted with 808 high cardiovascular risk participants of the Reus PREDIMED Centre. MetS was defined by the updated National Cholesterol and Education Program Adult Treatment Panel III criteria. An inverse association between quartiles of adherence to the MedDiet (14-point score) and the prevalence of MetS (P for trend<0.001) was observed. After adjusting for age, sex, total energy intake, smoking status and physical activity, participants with the highest score of adherence to the MedDiet (>/=9 points) had the lowest odds ratio of having MetS (OR [95% CI] of 0.44 [0.27-0.70]) compared to those in the lowest quartile. Participants with the highest MedDiet adherence had 47 and 54% lower odds of having low HDL-c and hypertriglyceridemia MetS criteria, respectively, than those in the lowest quartile. Some components of the MedDiet, such as olive oil, legumes and red wine were associated with lower prevalence of MetS. CONCLUSION: Higher adherence to a Mediterranean diet is associated with a significantly lower odds ratio of having MetS in a population with a high risk of cardiovascular disease.

• Factors associated with body dissatisfaction in non-clinical adolescents at risk of eating disorders

  Nancy Babio, Victoria Arija, Carolina Sancho, Josefa Canals

  J Public Health. 01/2008; 16:107–115.

  Aim To examine factors (individual, familiar and sociocultural) associated with body dissatisfaction (BD) by gender in non-clinical adolescents at risk of eating disorders (rED) and in a control group (CG). Subjects and methods A total of 2,967 adolescent students was screened using the Eating Attit... [more] Aim To examine factors (individual, familiar and sociocultural) associated with body dissatisfaction (BD) by gender in non-clinical adolescents at risk of eating disorders (rED) and in a control group (CG). Subjects and methods A total of 2,967 adolescent students was screened using the Eating Attitudes Test-40 and the Youth’s Inventory-4. Of these, 217 students (161 girls and 56 boys) identified as being at rED were chosen for the study, and 208 students (168 girls and 40 boys) were chosen as the CG. The subjects were given the Body Areas Satisfaction Test, the Youth’s Inventory-4, a questionnaire to evaluate social influences on the “model of thinness” (SIMT), the Family Environment Scale, and their body mass index (BMI) was determined. Results BD frequency in at-risk girls (44.6%) was significantly higher than in boys (27.3%). Girls at rED were most dissatisfied with their weight. BMIs were significantly higher and energy intake was significantly lower in dissatisfied girls than in satisfied girls at rED. In girls at rED, multiple linear regression analyses showed that SI-MT factors and dysthymia were associated with BD. In the CG, higher BMI were associated with BD. These relationships were not found in adolescent boys.

• Patrones dietéticos asociados al síndrome metabólico

  Nancy Babio, Mónica Bulló, Jordi Salas-Salvadó

  ACTUALIZACIÓN EN NUTRICIÓN. 01/2008; 9(4):300-310.

  RESUMEN El análisis de la ingesta a través de la identificación de patrones dietéticos permite examinar el potencial efecto combinado que tiene toda la dieta sobre la salud humana. Los patrones dietéticos pueden ser generados mediante un criterio a priori de acuerdo con conocimiento científico actua... [more] RESUMEN El análisis de la ingesta a través de la identificación de patrones dietéticos permite examinar el potencial efecto combinado que tiene toda la dieta sobre la salud humana. Los patrones dietéticos pueden ser generados mediante un criterio a priori de acuerdo con conocimiento científico actual de la nutrición humana o, a posteriori, mediante la utilización de métodos estadísticos, siendo los más habituales, el análisis factorial y el análisis por grupos. Diversos estudios epidemiológicos han evaluado la relación entre el patrón dietético y el Síndrome Metabólico (SM) o algunos de los componentes del mismo. Los estudios revisados indican que un patrón saludable, independientemente de la denominación que reciba, caracterizado principalmente por un alto consumo de vegetales, frutas, legumbres, pescado, moderadas cantidades de alcohol y baja ingesta de carnes rojas, productos cárnicos procesados, carbohidratos refinados y lácteos enteros, se asocia inversamente con la prevalencia de SM y/o con algunos de los componentes del mismo. Palabras claves: Síndrome metabólico; Patrones dietéticos; Dieta; Diabetes; Dislipemia; Hipertensión. Abreviaturas utilizadas: SM: Síndrome Metabólico. SUMMARY To analyze the intake through the identification of dietary patterns allows the examination of the potential combined effect of the whole diet on human health. The dietary patterns can be generated a priori by a criteria according to current scientific knowledge of human nutrition, or a posteriori using statistical methods, being factor analysis and cluster analysis the commonest ones. Several epidemiological studies have assessed the relationship between dietary pattern and the Metabolic Syndrome (SM) or some of its features. The revised studies indicate that a healthy pattern, regardless how it is labelled, mainly characterized by a high consumption of vegetables, fruits, legumes, fish, moderate alcohol consumption and low intake of red meat, processed red meat, full-fat dairy and refined carbohydrates were associated with a lower prevalence of MS and/or its features. Keywords: metabolic syndrome, dietary patterns, diet, diabetes, dyslipemia, hypertension. Abbreviations: MS (Metabolic Syndrome)
• 0.48

  Impact points

  [Mediterranean Diet and the sea: fishes]

  Victoria Arija Val, Nancy Babio, Joan Fernández-Ballart, Lluís Serra-Majem

  Archivos latinoamericanos de nutrición. 07/2004; 54(2 Suppl 1):72-5.

  The excellent quality of the Mediterranean Diet, apart from other products, is associated to a high consumption of fish. Epidemiological studies have shown over time certain beneficial effects of fish consumption in the prevention of chronic diseases. The specific components found in fish, the long ... [more] The excellent quality of the Mediterranean Diet, apart from other products, is associated to a high consumption of fish. Epidemiological studies have shown over time certain beneficial effects of fish consumption in the prevention of chronic diseases. The specific components found in fish, the long chain omega 3 eicosapentanoic and docosahexanoic fatty acids, have been identified as the principle elements responsible for this protective effect in Mediterranean populations. There is also evidence for a relationship between elevated fish consumption and reduced cardiovascular mortality, especially in populations at greater risk for this disease or those with high fatty fish intakes. Moreover, fish consumption of > or = 3.5 servings/week appears to have a protective effect against certain site specific cancers, and is also associated with a number of lifestyle factors. It's been shown that this protective effect is reduced in those who smoke, consume alcohol, are less physically active and who consume fish preserved in salt. However, these preventive effects are seen fundamentally when lipid profiles approximate those typical of the Mediterranean Diet, which is also rich in monounsaturated fatty acids. In light of new evidence, current nutritional objectives for the Spanish population recommend that polyunsaturated fatty acids account for 5% of total calories, with an omega6:omega3 ratio ranging from 6/1 to 10/1.

• Incorporación del dietista-nutricionista en el Sistema Nacional de Salud (SNS): Declaración de Postura de la Asociación Española de Dietistas-Nutricionistas (AEDN)

  Giuseppe Russolillo Femenías, Eduard Baladia, Manuel Moñino, María Colomer, Marta García, Julio Basulto, Iva Marques, Nancy Babio, Maria Manera, Pilar Cervera

  Actividad dietética, ISSN 1138-0322, Vol. 13, Nº. 2, 2009, pags. 62-69.

  El presente documento tiene como objetivo justifi car la incorporación del dietista-nutricionista en los equipos multidisciplinarios de atención primaria, especializada y de salud pública que dispensan atención sanitaria integrada según su papel específi co en la promoción, la prevención, el tratami... [more] El presente documento tiene como objetivo justifi car la incorporación del dietista-nutricionista en los equipos multidisciplinarios de atención primaria, especializada y de salud pública que dispensan atención sanitaria integrada según su papel específi co en la promoción, la prevención, el tratamiento y la rehabilitación de enfermedades prevalentes en España, y con ello benefi cian a la salud individual y colectiva de los ciudadanos y ciudadanas. The purpose of this document is to justify including the dietician-nutritionist in the multi-disciplinary, specialist and public health primary care teams which give integrated health care based on their particular role in promoting, preventing, treating and rehabilitating diseases that prevail in Spain, thereby benefi ting the citizens� individual and collective health.

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• 1.07

  Impact points

  Dietary fibre: influence on body weight, glycemic control and plasma cholesterol profile.

  N Babio, R Balanza, J Basulto, M Bulló, J Salas-Salvadó

  Nutrición hospitalaria : organo oficial de la Sociedad Española de Nutrición Parenteral y Enteral. 25(3):327-40.

  There have been several studies on the effects of dietary fibre on the metabolism. Epidemiologic studies have consistently reported an inverse relationship between dietary fibre and type 2 diabetes mellitus or cardiovascular mortality. This review focuses on observational and experimental studies th... [more] There have been several studies on the effects of dietary fibre on the metabolism. Epidemiologic studies have consistently reported an inverse relationship between dietary fibre and type 2 diabetes mellitus or cardiovascular mortality. This review focuses on observational and experimental studies that examine the effect of different types and sources of dietary fibre on body weight, glucose metabolism and lipid profile. From the available evidence, we conclude that clinical studies consistently show that the intake of viscous dietary fibre decreases the low density lipoprotein cholesterol and postprandial glucose levels, and induces short term satiety. However, few clinical trials have demonstrated that the intake of dietary fibre has a positive effect on the control of diabetes and body weight.
• 1.07

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  Non-clinical adolescent girls at risk of eating disorder: under-reporters or restrained eaters?

  N Babio, J Canals, J Fernández-Ballart, V Arija

  Nutrición hospitalaria : organo oficial de la Sociedad Española de Nutrición Parenteral y Enteral. 23(1):27-34.

  BACKGROUND: To evaluate the plausibility of self-reported energy intake, Goldberg et al proposed a technique to identify the miss-reporters. SUBJECTS: After screening 2,967 adolescents by EAT-40 test, 132 at risk of ED and 151 as a control group were studied. AIM: To determine whether subjects at ri... [more] BACKGROUND: To evaluate the plausibility of self-reported energy intake, Goldberg et al proposed a technique to identify the miss-reporters. SUBJECTS: After screening 2,967 adolescents by EAT-40 test, 132 at risk of ED and 151 as a control group were studied. AIM: To determine whether subjects at risk of eating disorders that are identified as under reporters can be considered as UR or in turn as restrained eaters. METHODS: We determined dietary energy intake, body mass index, body satisfaction, physical activity, psychopathology, dietary restraint factor, weight loss and diagnoses of eating disorders. We applied Goldberg's equations to identify under reporters. RESULTS: 40.9% of girls at risk of eating disorders were identified as under reporters and only 7.3% were in the control group. A total of 64.4% of the Eating Disorders Not Otherwise Specified were under reporters. The body mass index of under reporters was significantly higher than in the other of subjects regardless of whether they were at risk of eating disorders. Girls at risk of eating disorders and under reporter had significantly lower body satisfaction than other groups. Multiple logistic regressions in all subjects showed that the risk of being UR was associated with an increase in the body mass index, increase in dietary restraint scores and weight loss; whereas, that only the body mass index was associated with the control group. CONCLUSION: The prevalence of under reporter increases with the severity of the eating disorders several adolescent girls at risk of eating disorder and identified by Goldberg cut-off technique as under reporter may to be restricting their intake and therefore they would not be under reporter.
• 1.07

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  A two-phase population study: relationships between overweight, body composition and risk of eating disorders.

  N Babio, J Canals, A Pietrobelli, S Pérez, V Arija

  Nutrición hospitalaria : organo oficial de la Sociedad Española de Nutrición Parenteral y Enteral. 24(4):485-91.

  BACKGROUND: Overweight and eating disorder (ED) are major public health problems in adolescents. Aims: To assess the association of overweight, body composition and anthropometric characteristics with the probability being at risk of ED. METHODS: A two-phase study was used. 329 girls and 96 boys (ag... [more] BACKGROUND: Overweight and eating disorder (ED) are major public health problems in adolescents. Aims: To assess the association of overweight, body composition and anthropometric characteristics with the probability being at risk of ED. METHODS: A two-phase study was used. 329 girls and 96 boys (aged 12-18 years) from an initial sample of 2967 adolescents were studied. The BMI, percentage of fat mass estimated by bioimpedance (FM(BIA)), waist circumference, waist-to-height ratio, and waist-to-hip ratio (WHipr) were calculated. The Eating Attitudes Test, Youth's Inventory-4 and a questionnaire to evaluate social influences were administered. RESULTS: A total of 34.7% of girls and 53.6% of boys at risk of ED were overweight (including obesity). For girls, overweight frequency was significantly higher in risk ED group than in control group. Increases of one point in the BMI or FM(BIA) increased the probability of being at risk of ED by 12% (3.0-19.0) and 4% (0.0-8.0), respectively. An increase in WHipr was negatively associated with ED risk. Smoking and symptoms of dysthymia and the genralized anxiety disorder also increase the probability of being at risk of ED in adolescent girls. In adolescent boys, these relations were not observed. CONCLUSIONS: The higher BMI and the percentage of FM(BIA) are associated with greater risk of ED in adolescent girls, when psychological factors are present. Increases in the WHipr, characteristic of childhood body is negatively associated with that risk.