Namkug Kim
Ph.D.
a
a
a
a
36.14

Topics (35) View all

Skills (16)

Research experience

  • Jan 2012
    Research: Korea Basic Science Institute KBSI
    Korea Basic Science Institute KBSI
    South Korea · Seoul
  • Jan 2012
    Research: University of California, Los Angeles
    University of California, Los Angeles
    USA · Los Angeles
  • Jan 2012
    Research: Sungkyunkwan University
    Sungkyunkwan University · Samsung Medical Center
    South Korea · Seoul
  • Jan 2010–
    Dec 2011
    Research: University of Utah
    University of Utah
    USA · Salt Lake City
  • Jan 2010
    Research: Catholic University of Korea
    Catholic University of Korea · Department of Psychiatry
    South Korea · Seoul
  • Jan 2009
    Research: CHA University
    CHA University · College of Medicine
    South Korea · Seoul
  • Jan 2008–
    Dec 2012
    Research: Asan Medical Center
    Asan Medical Center
    South Korea · Seoul
  • Jan 2008–
    Dec 2012
    Research: University of Ulsan
    University of Ulsan · Department of Radiology
    South Korea · Ulsan
  • Jan 2008
    Research: Kangwon National University
    Kangwon National University · Department of Internal Medicine
    South Korea · Syunsen
  • Jan 2006
    Research: Lantheus Medical Imaging
    Lantheus Medical Imaging
    USA · Lowell
  • Jan 2005
    Research: Harvard University
    Harvard University
    USA · Cambridge
  • Jan 2001–
    Dec 2011
    Research: Seoul National University
    Seoul National University · Department of Industrial Engineering
    South Korea · Seoul

Education

  • Sep 2008–
    Oct 2009
    The Brain Institute, Univ. of Utah
    Neuro/Brain Image Processing, MR Spectroscopy, Ephydemiology · Post-Doc. Research Felllow
    USA · Salt Lake City
  • Sep 2004–
    Feb 2008
    Seoul National University
    Medical Image Processing (Industrial Engineering) · PhD
    South Korea · Seoul
  • Mar 1995–
    Feb 1997
    Seoul National University
    Industrial Engineering · MS
    South Korea · Seoul
  • Mar 1991–
    Feb 1995
    Seoul National University
    Industrial Engineering · BS
    South Korea · Seoul

Awards & achievements

  • Jun 2012
    Grant: 방사선 피폭 저감 및 시술 정확도 향상을 위한 복부 및 흉부 1cm급 병소 생검 및 치료용 바늘 삽입형 영상중재시술 로봇시스템 개발, Development of Needle Insertion Type Image-based Interventional Robotic System for Biopsy and Treatment of 1-cm Abdominal and Thoracic Lesion with Reduced Radiation Exposure and Improved Accuracy, 지식경제 기술혁신사업 산업융합원천기술개발사업 PI 서준범, (co-PI), 2012.6.01~2017.05.31
  • Oct 2011
    Grant: 기도폐쇄성폐질환 환자에서 기도반응성 약제 효과 판정을 위한 CT영상 및 분석기법 개발 및 검증, 보건복지부, PI 서준범, (Researcher), 2011.10.01~2014.09.30
  • Jul 2011
    Grant: 최소 침습 수술 및 중재시술을 위한 자동화 의료기기 개발사업 기획, A planning on development of automated medical device for minimal invasive and interventional surgery, 보건복지부, 보건의료연구개발사업, 2011.07.01. ∼ 2011.10.31. USD 50,000, Researcher, PI 서준범 (기획과제)
  • Jul 2011
    Grant: 최소 침습 수술 및 중재시술을 위한 자동화 의료기기 개발사업 기획, A planning on development of automated medical device for minimal invasive and interventional surgery, 보건복지부, 보건의료연구개발사업, 2011.07.01. ∼ 2011.10.31. USD 50,000, Researcher, PI 서준범 (Researcher)
  • Jun 2011
    Award: Best Poster Award, 3차원 거리변환과 free-formed surface fitting 알고리즘을 이용한 흉부 CT 영상에서의 자동 좌우 폐 분할, 이연주, 김남국, 서준범, KSIIM
  • Jun 2011
    Grant: Development of surgical robot of laparoscopy, ENT, and neurosurgery using minimal invasive surgical instrument and real time medical image and guidance technology, MKE, 2011.06.01~2016.05.31 (coPI)
  • May 2011
    Grant: 세계 선도 의과학자 육성 전략 연구, A research on strategies to raise world-leading bio-medical scientists, 보건복지부, 보건의료연구개발사업, 2011.05.01. ∼ 2011.08.31, USD 50,000, Researcher, PI 고재영 (기획과제)
  • May 2011
    Grant: 로봇 시범사업 과제, 로보닥 제어기 임상 프로세스 보완 및 의료영상 S/W 개선 연구과제 수행 계획서, 지식경제부, Hyundai Heavy Industries Co., Ltd, 2011.05.01~2013.12.31
  • Mar 2011
    Grant: Development of medical-image-based total knee replacement and total hip replacement arthroplasty planning software, Hyundai Heavy Industries Co., Ltd, 2011.03.01~2013.02.28, PI
  • Jan 2011
    Award: Scientific Paper Award, Automatic Classification of Regional Disease Pattern of Diffuse Lung Disease at HRCT: Cross-Vendor Study, Kim N, Lee Y, Seo JB, Lynch DA, 5th IWPFI & 3rd JSPFI, Awaji Island, Japan, Jan 28-30 2011
  • Jan 2011
    Award: Scientific Presentation Award, Nonembolic Causes of Perfusion Defect on Contrast-enhanced Dual-Energy CT: Review of 85 Consecutive Cases, Lim CH, Seo JB, Kim N, Chae EJ, Hwang HJ, Lee HJ, Song JW, Lee JS, Song KS, 5th IWPFI & 3rd JSPFI, Awaji Island, Japan, Jan 28-30 2011,
  • Jan 2011
    Award: Scientific Presentation Award, Prediction of postoperative lung function in patients with lung cancer: comparison of dual-energy perfusion CT and perfusion scintigraphy, Chae EJ, Seo JB, Song JW, Kim N, Park JY, Lee HJ, Hwang HJ, Lim C, Kim YH., 5th IWPFI & 3rd JSPFI, Awaji Island, Japan, Jan 28-30 2011
  • Jan 2011
    Award: Scientific Presentation Award, Enhancement of Computerized Differentiation Accuracy of Region Pattern of Diffuse Infiltrative Lung Disease Using Local Context Sensitive SVM Classifier, Kim N, Lim J, Seo JB, 5th IWPFI & 3rd JSPFI, Awaji Island, Japan, Jan 28-30 2011
  • Nov 2010
    Award: Certificate of Merit, Clinical Applications of a Dual-Energy CT in Thorax J. Kim, MD, E. Chae, MD; J. Seo, MD, PhD; J. Song, MD; N. Kim, PhD; B. Krauss, PhD, Radiology Society of North America (RSNA) 2010, 2010/11/28~2010/12/03
  • Nov 2010
    Award: Certificate of Merit, Image-based Phenotyping of COPD Y. Lee, J. Seo, MD, PhD; N. Kim, PhD; E. Chae, MD; Y. Oh, MD, PhD; S. Lee, MD, Radiology Society of North America (RSNA) 2010, Co-author, 2010/11/28~2010/12/03
  • Oct 2010
    Grant: Intelligent image diagnosis and therapy-support system, World Best Software, Korea Evaluation Institute of Industrial Technology, 2010.10.01 ~ 2013.03.31 (coPI)
  • Sep 2010
    Grant: BOLD 영상을 이용한 종양 내 산소 포화도와 관류량의 정량적 측정기술의 개발: 동물 실험 모델을 이용한 측정 기술의 최적화 및 임상 적용, 기초연구사업 -> 일반연구자지원사업 -> 기본연구지원사업, 울산대학교 산학협력단, 2010-09-01~2013-08-31, PI김정곤, (연구원)
  • Sep 2010
    Grant: The Development of Analysis Software with MR Spectroscopy and MRI : Validation using Mild Hypoxic Rat Brain, Basic Science Research Program, Ministry of Education, Science and Technology, 2010.9.1~2011.8.31
  • Jul 2010
    Grant: The Development of MR Spectroscopy Analysis and Regression Software using CSI and MRI for Analyzing Rat Brain Metabolite with Mild Hypoxia, Asan Institute for Life Science, 2010.7.1 ~ 2011.12.31
  • Jul 2010
    Grant: 64비트 PC 기반의 고성능 폐영상 분석 프로그램 개발 및 상품화, 중소기업기술개발지원 사업, Small & Medium Business Administration, 2010.07.01 ~ 2011.06.30, USD330,000, 위탁
  • Mar 2010
    Grant: Development of analysis, visualization and mechanical stability evaluation tool for 3-dimensional micro-architecture of bone trabeculae using 3-dimensional MRI in osteoporosis patients, 연구장비공동활용활성화사업, Ministry of Education, Science and Technology (KBSI), 2010.3.1~2012.12.31, co-P.I
  • Mar 2010
    Award: The Outstanding Scientific Presentation by a Fellow, Quantitative Assessment of Air Trapping in Patients with COPD by using Automatic Registration of Inspiration/Expiration CT Scans, Chae EJ, Lee HJ, Seo JB, Paik SH, Lee JJ, Kim NK, Oh YM, Lee SD, Lee CW, Society of Thoracic Radiology (STR) 2010, San Diego, California, Feb 28 – March 3. 2010,
  • Jan 2010
    Award: Certificate of Merit, Non-Radioactive Xenon ventilation imaging using dual energy CT in asthmatics: initial experience. Chae EJ, Seo JB, Lee J, Kim N, Goo HW, Cho YS. 2010 5th Joint Meeting of Korean-Japanese Society of Thoracic Radiology, 2010/01/29-30
  • Dec 2009
    Award: Second place recipient of the Journal of Digital Imaging 2009 Best Paper Award, Development of an automatic classification system for differentiation of obstructive lung disease using HRCT. N. Kim, J.B. Seo, Y. Lee, J.G. Lee, S.S. Kim, and S.H. Kang, J Digit Imaging, 2009. 22(2): p. 136-48.
  • Jun 2009
    Grant: Development of early cancer detection and diagnosis using diffusion weighted imaging, Small & Medium Business Administration, 2009.06.01～2010.05. 31, Internal Investigator
  • Apr 2009
    Grant: Development of early cancer detection and computer aided diagnosis system using perfusion images, MKE, 2009.04.01～2010.03. 31 USD200,000, Internal Investigator
  • Jan 2009
    Grant: Development of computer aided diagnosis for early cancer detection and quantitative treatment response, Asan Institute for Life Science, 2008.11.17, 2009.01.14-2009.12.31, USD 20,000, co P.I
  • Nov 2008
    Grant: A development of computer-aided diagnosis on semiconductor defect factor using content-based image retrieval, D01234, Basic research support basic science, 2008.11.01-2009.10.30, Internal Investigator
  • Nov 2008
    Award: Certificate of Merit, An Efficient Automatic Classifier for Differentiation of Diffuse Infiltrative Diseases on Whole Lung HRCT Using a Level-set Based Diseased Lung Segmentation, Non-linear Binning Strategy, Cascading SVM (Support Vector Machine) Classification, Kim N, Seo JB, Park SO, Lee YJ, Lee J Radiology Society of North America (RSNA) 2008/12/02
  • Oct 2008
    Award: Silver Award: Quantitative Assessment of Air Trapping by Using Automatic Registration and Subtraction of Inspiration/Expiration CT Scans: Studies on Healthy Individuals and Asthmatics. Chae EJ, Seo JB, Lee J, Kim N, Kim TB, Lee SD. 2008 International Summit. The Future of Quantitative and Functional Lung Imaging (Oct 2-4, Iowa City, Iowa).
  • Oct 2008
    Award: GE Best Student paper award, Segmentation of airway tree at volumetric CT with adaptive thresholding based on local dilation & connected component analysis and leakage control: Comparison with a conventional region growing method, BW Park, N Kim, JB Seo, 1st Korean Medical Image Conference, 2008, CA, 2008/10/01,
  • Jun 2008
    Grant: Probing Neural Mechanisms Underlying Associations between Diabetes and Accelerated Cognitive Decline and Depression: A Multimodal Longitudinal Neuroimaging Study (P.I.: Inkyoon Lyoo), Korean Research Foundation, Global Research Network Support, E00021, 2008.6.1-2011.5.31, USD100,000, co P.I
  • Jan 2008
    Grant: Asthma Diagnosis and Treatment Response Evaluation, Asan Institute for Life Science, 2008.01.01-2008.12.31, USD 20,000, co P.I
  • Jan 2008
    Grant: Establishment of Xenon inspiration CT imaging method using dual energy and development of local ventilation analysis software using Xenon imaging, Asan Institute for Life Science, 2008.01.01-2008.12.31, USD 20,000, coPI
  • Jan 2008
    Grant: Establishment of Xenon inspiration CT imaging method using dual energy and development of local ventilation analysis software using Xenon imaging, Asan Institute for Life Science, 2008.01.01-2008.12.31, USD 20,000, co P.I
  • Oct 2007
    Award: The 3rd Prize, 3D Segmentation in the Clinic: A Grand Challenge, The Medical Image Computing and Computer Assisted Intervention (MICCAI) 2007.10.29
  • Feb 2007
    Award: Honorable Mention Poster Award, The performance improvement of differentiation among obstructive lung diseases on the basis of the features of texture and shape analysis at HRCT, Lee YJ, Kim N, Seo JB, Lee JG, Kang SH, SPIE Medical Imaging 2007 Symposium, Corresponding Author, 2007/02/17-22
  • Jan 2007
    Grant: Evaluation of pulmonary ventilation and perfusion with dual-energy CT technique: Animal experiment and clinical application), Asan Institute for Life Sciences, USD 22,000, 2007, PI: Seo, JB, Internal Investigator
  • Jan 2007
    Grant: The Development and Validation of Computer Aided Diagnosis through the Textural and Shape Feature Extraction of Computed Tomographic Images for the Quantification of Diffuse Interstitial Lung Disease Using Artificial Intelligence, Korea Research Foundation, USD 44,000, 2007, PI: Seo, JB, Internal Investigator
  • Jun 2006
    Award: Bronze Award, Quantitative assessment of emphysema and airway dimension at CT in chronic obstructive lung disease: correlation with pulmonary function test and dyspnea score, Lee YK, Seo JB, Kim NK, Oh YM, Lee SD, Do KH, Lee JS, 1st Asian Congress of Thoracic Radiology(ACTR 2006), June 16-17, 2006
  • May 2006
    Grant: Development and validation of Computer aided diagnosis imaging for early detection and tumor staging of gastric cancer, A06-00042745, Korea Ministry of Health & Welfare, USD60,000/y x 2, 2006.05-2008.03, PI: Kim, AY, Internal Investigator
  • Mar 2006
    Grant: Tumor perfusion imaging for in-vivo quantification and visualization of tumor neoangiogenesis: Experimental animal model-based software development and clinical evaluation weighted on prostate cancer, R01-2006-000-10998-0, Korea Ministry of Science & Technology, USD100,000/y x 3, 2006/03-2009/02, PI
  • Mar 2006
    Grant: Research and Development of Tumor Perfusion Imaging in Prostate Cancer , Korea Research Foundation, 2006.3 – 2007.2, PI Kim, JK, Internal Investigator
  • Mar 2006
    Grant: Development and Validation of Quantitative and Functional Evaluation System on Chronic Obstructive Pulmonary Disease using Computed Tomography, Korea Science and Engineering Foundation USD360,000, 2006-2008, PI: Seo, JB, Internal Investigator
  • Mar 2006
    Grant: Functional and Structural Connectivity of Brain in Posttraumatic Stress Disorder: Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging Study, 800-20060206 (P.I.: Lyoo IK), Korean Ministry of Health and Welfare, 2006/03- 2008/03, Internal Investigator
  • Mar 2006
    Grant: Development and Validation of Quantitative and Functional Evaluation System on Chronic Obstructive Pulmonary Disease using Computed Tomography, R01-2006-000-11244-0, Korea Ministry of Science & Technology, 2006/03-2009/02, PI: Seo, JB, Internal Investigator
  • Feb 2006
    Grant: Functional and Structural Connectivity of Brain in Posttraumatic Stress Disorder: Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging Study, 800-20060206, Korean Ministry of Health and Welfare, 2006/03- 2008/03, PI: Lyoo IK, Internal Investigator
  • Jan 2006
    Grant: The Neurochemical Changes in Patients with PTSD: A Long-Term Follow-up Study, KRF-2006-331-E00187 Korean Research Foundation, Young Investigator Award, 2006-2007, PI: Lyoo IK, Internal Investigator
  • Jan 2006
    Grant: The Neurochemical Changes in Patients with PTSD: A Long-Term Follow-up Study, KRF-2006-331-E00187 (P.I.: Lyoo IK), Korean Research Foundation, Young Investigator Award, 2006-2007, Internal Investigator
  • Jan 2006
    Grant: Development of Automatic Liver and Lobe Segmentation Using 3D CT Data: Establishment of Basis for Computer-Aided Presurgical Planning of Hepatic Surgery and Computer-Aided Diagnosis (CAD) of Hepatic Diseases, Asan Institute for Life Science, USD20,000, 2006, PI: Won, HJ, Internal Investigator
  • Jan 2006
    Award: Tumor Volumetry/Follow-up, Asan Institute for Life Science, USD20,000, 2006.01-2006.12, PI: Won, HJ, Internal Investigator
  • Jan 2006
    Grant: Tumor Volumetry/Follow-up, Asan Institute for Life Science, USD20,000, 2006.01-2006.12, PI: Won, HJ, Internal Investigator
  • Nov 2005
    Award: Certificate of merit, Radiographics invitation at RSNA 2005, 2005/11/27-12/02
  • Jan 2005
    Grant: Development and Validation of Quantitative and Functional Evaluation System on Chronic Obstructive Pulmonary Disease using Computed Tomography, Korea Ministry of Science & Technology, USD120,000/y x 3, 2005 ~ 2007, PI: Seo, JB, Internal Investigator
  • Jan 2005
    Grant: Evaluation of pulmonary ventilation and perfusion with functional magnetic resonance imaging in patients with pulmonary emphysema: comparison with computed tomography and pulmonary function test, Asan Institute for Life Sciences USD9,000, 2005, PI: Seo, JB, Internal Investigator
  • Jan 2005
    Grant: Research on the Development of Computer Aided Diagnosis Techniques through the Feature Extraction of Computed Tomographic Images in the Classification of Chronic Obstructive Lung Disease, Korea Research Foundation, USD 20,000, 2005.01-2005.12, PI: Seo, JB, Internal Investigator
  • Dec 2004
    Grant: Clinical research center for chronic obstructive airway disease (P.I.: Seo, JB), 0412-CR03-0704-0001, Korea Ministry of Health & Welfare, 2004/12-2013/11
  • Dec 2004
    Grant: Clinical research center for chronic obstructive airway disease, 0412-CR03-0704-0001, Korea Ministry of Health & Welfare, 2004/12-2013/11, PI: Seo, JB, Internal Investigator
  • Dec 2004
    Grant: Clinical research center for chronic obstructive airway disease 0412-CR03-0704-0001, , Korea Ministry of Health & Welfare, overall USD900,000/y x 9, 2004.12~2013.11, PI: Lee, SD, (coPI Seo, JB USD30,000/y x 9), Internal Investigator
  • Apr 2004
    Grant: Health Technology Infrastructure Development Project, Ministry of Health and Welfare, Korea, 2003.07-2004.04, PI Lyoo IK, Internal Investigator
  • Jan 2003
    Grant: Development of Dental Implants Planning Software for Hitachi Cone Beam CT Hitachi Medical, Japan, 2003-, Royalty based, PI: Kim, NK
  • Nov 2002
    Award: Best Paper Award, Development of a robot arm-type navigator for pedicle screw insertion, The 19th Annual Fall Meeting of the Korean Society of Spine Surgery, Nov., 2002
  • Oct 2002
    Award: Best Poster Award, Development and an Accuracy Test of a Robot-arm Type Image-guided Surgery System, The 46th Annual Fall Congress of the Korean Orthopaedic Association, Oct., 2002
  • Jul 2002
    Grant: 경피적천장관절나사고정술지원용 로봇암형 영상유도장치의 개발 및 정확도 평가에 관한 연구, 우수연구자지원, 교육과학기술부, 2002.07-2003.06, PI: Yeom, JS, Internal Investigator
  • Feb 2002
    Award: Best paper award, A personal computer-based surgical simulation system for spinal pedicle screw insertion, Bumsuk academic scholarship foundation, Feb., 2002
  • Oct 2001
    Grant: 편측하악골 왜소증의 자동화 컴퓨터 가상 수술 기법의 개발, 선도연구자지원사업 우수연구자지원, 교육과학기술부, 2001.10-2003.09, PI : Kim YO, Internal Investigator
  • Oct 2001
    Award: Basic Science Research Award, Patient-specific surgical simulator for spinal screw insertion composed of virtual roentgenogram, virtual C-arm, and rapid prototyping, The Journal of the Korean Orthopaedic Association, Oct., 2001
  • Jul 2001
    Grant: 3차원 의료영상재구성에 의한 가상시술 소프트웨어 개발, 중소기업기술혁신개발, 중소기업청, 2001.07-2002.06, PI
  • Jan 2001
    Grant: Development of neuro-surgical navigation system, Korea Ministry of Commerce, Industry, and Energy, 2001-2003, USD400,000, PI
  • Nov 2000
    Award: Best Paper Award, Patient-specific surgical simulator for spinal screw insertion composed of virtual roentgenogram, virtual C-arm, and rapid prototyping, The 16th Annual Fall Meeting of the Korean Society of Spine Surgery, Nov., 2000
  • Jan 2000
    Grant: Development of treatment planning software for oral and maxillofacial surgery and surgery support template, 2000, Korea Ministry of Health & Welfare, USD100,000
  • Jan 2000
    Grant: Development of treatment planning system for pedicle spine screw insertion and pedicle screw guiding RP template design system, Korea Ministry of Health & Welfare, 2000, USD100,000
  • Jan 2000
    Grant: Development of Medical 3D Model Fabrication S/W using Rapid Prototyping, Korea Ministry of Information & Communication, 2000, USD100,000, PI
  • Nov 1999
    Award: Best Paper Award, Distributed Concurrent Engineering: Internet-Based Interactive 3-D Dynamic Browsing and Markup of STEP Data, Concurrent Engineering: Research and Applications, Concurrent Engineering: Research and Applications, 1999. , Co-Author, 1999/11/01
  • Jan 1999
    Grant: Development of diagnosis and surgery support tool based on PC for oral and maxillofacial surgery, Korea Ministry of Health & Welfare, 1999, USD50,000
  • Jan 1999
    Grant: Development of 3D virtual endoscopy simulation system using VRML and DICOM, Korea Ministry of Health & Welfare, 1999, USD50,000
  • Jan 1999
    Grant: Development of simulator using high speed network, Korea Ministry of Information & Communication, 1999, USD100,000
  • Jan 1999
    Grant: Development of cephalometry planning software, Korea Ministry of Health & Welfare, 1999, USD70,000
  • Jan 1998
    Grant: Development of STL viewer for fabricating anatomical model using Rapid Prototyping (S/W and game area), Korea Small & Medium Business Administration, 1998, USD100,000
  • Jan 1998
    Grant: Development of constructing technique of 3D anatomical model using X-Ray images on high speed network, Korea Ministry of Information & Communication, 1998, USD50,000
  • Jan 1998
    Grant: Development of bone segmentation technique and simulator for bone joining surgery, Korea Ministry of Information & Communication, 1998, USD70,000
  • Jan 1998
    Grant: Development of 3D medical interactive education system using VRML, Korea Ministry of Information & Communication, 1998, USD50,000
  • Jan 1997
    Grant: Development of web visualization and sharing technology of 3D ultrasound data, Korea Ministry of Information & Communication, 1997, USD50,000
  • Jan 1997
    Grant: Development of generating STL format from CT/MRI volume data for fabrication of Skull Implants, Korea Ministry of Information & Communication, 1997, USD40,000

Publications (93) View all

  • Source
    Article: Hepatic fat quantification: a prospective comparison of magnetic resonance spectroscopy and analysis methods for chemical-shift gradient echo magnetic resonance imaging with histologic assessment as the reference standard.
    Bo-Kyeong Kang, Eun Sil Yu, Seung Soo Lee, Youngjoo Lee, Namkug Kim, Claude B Sirlin, Eun Yoon Cho, Suk Keu Yeom, Jae Ho Byun, Seong Ho Park, Moon-Gyu Lee
    [show abstract] [hide abstract]
    ABSTRACT: The aims of this study were to assess the confounding effects of hepatic iron deposition, inflammation, and fibrosis on hepatic steatosis (HS) evaluation by magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) and to assess the accuracies of MRI and MRS for HS evaluation, using histology as the reference standard. In this institutional review board-approved prospective study, 56 patients gave informed consents and underwent chemical-shift MRI and MRS of the liver on a 1.5-T magnetic resonance scanner. To estimate MRI fat fraction (FF), 4 analysis methods were used (dual-echo, triple-echo, multiecho, and multi-interference), and MRS FF was calculated with T2 correction. Degrees of HS, iron deposition, inflammation, and fibrosis were analyzed in liver resection (n = 37) and biopsy (n = 19) specimens. The confounding effects of histology on fat quantification were assessed by multiple linear regression analysis. Using the histologic degree of HS as the reference standard, the accuracies of each method in estimating HS and diagnosing an HS of 5% or greater were determined by linear regression and receiver operating characteristic analyses. Iron deposition significantly confounded estimations of FF by the dual-echo (P < 0.001) and triple-echo (P = 0.033) methods, whereas no histologic feature confounded the multiecho and multi-interference methods or MRS. The MRS (r = 0.95) showed the strongest correlation with histologic degree of HS, followed by the multiecho (r = 0.92), multi-interference (r = 0.91), triple-echo (r = 0.90), and dual-echo (r = 0.85) methods. For diagnosing HS, the areas under the curve tended to be higher for MRS (0.96) and the multiecho (0.95), multi-interference (0.95), and triple-echo (0.95) methods than for the dual-echo method (0.88) (P ≥ 0.13). The multiecho and multi-interference MRI methods and MRS can accurately quantify hepatic fat, with coexisting histologic abnormalities having no confounding effects.
    Investigative radiology 04/2012; 47(6):368-75. · 4.85 Impact Factor
  • Source
    Article: Cocaine use in the past year is associated with altitude of residence.
    Kristen K Fiedler, Namkug Kim, Douglas G Kondo, Perry F Renshaw
    [show abstract] [hide abstract]
    ABSTRACT: : Recently, increased rates of suicide in US counties at higher altitudes have been noted. Because of the documented association between cocaine use and suicide, we hypothesized that there would be a correlation between incidence of cocaine use and altitude of residence. : Cocaine use data were obtained from the Substate Substance Abuse Estimates from the 1999-2001 National Surveys on Drug Use and Health. Data related to the percentages of people 12 years or older who used cocaine in the past year. Average elevation for US counties was calculated using the Shuttle Radar Topography Mission elevation data set, and subject region elevation was calculated by averaging the weighted elevations of each region's relevant counties. The correlation between elevation of a substate region and incidence of cocaine use in that region was calculated using Pearson correlation coefficients. : A significant correlation exists between mean altitude of a substate region and incidence of cocaine use in that region (r = 0.34; P < 0.0001). Regression analysis controlling for age, sex, race, education level, income, unemployment, and population density was performed. Altitude remained a significant factor (P = 0.007), whereas male sex (P = 0.008) and possessing less than a college education (P < 0.0001) were also significant predictors of self-reported cocaine use in the past year. It is important to note that cocaine use was assessed in isolation of other drugs of abuse, an additional confounding variable. : This study demonstrates a significant correlation between altitude of substate region of residence and incidence of cocaine use. It is possible that stress response due to hypoxia is responsible; however, this requires further investigation. However, because other substance use was not assessed, specificity of this association is unknown. In addition, this correlation may help explain the increased rate of suicide in areas of higher elevation.
    Journal of Addiction Medicine 04/2012; 6(2):166-71. · 1.95 Impact Factor
  • Article: Volumetric, planar, and linear analyses of pharyngeal airway change on computed tomography and cephalometry after mandibular setback surgery.
    Jae-Woo Park, Nam-Kug Kim, Jong-Wan Kim, Myung-Jin Kim, Young-Il Chang
    [show abstract] [hide abstract]
    ABSTRACT: The purpose of this study was to use lateral cephalometry and computed tomography (CT) to examine the volumetric, planar, and linear changes in the pharyngeal airway after mandibular setback surgery. The pharyngeal airways of 12 subjects who underwent mandibular setback surgery at Seoul National University Dental Hospital were assessed linearly and volumetrically on lateral cephalometric radiographs and CT before surgery and 6 months after surgery. The pharynx, nasopharynx, and oropharynx were evaluated by volumetric analysis. Pharyngeal depth, airway space, pharyngeal soft-tissue thickness, and hyoid bone position were measured by linear analysis. The axial section area of the airway was measured by area analysis. From the linear analysis, a significant decrease in pharyngeal depth and a significant posterior movement of the hyoid bone (P <0.05) were noted. Volumetric analysis by CT showed that the oropharynx decreased after mandibular setback surgery. However, the volume and the axial section area of the airway in the CT images did not change significantly after mandibular setback surgery (P >0.05). Although the structures around the mandible inevitably moved backward after mandibular setback surgery on linear analysis, physiologic deformation could occur to preserve the airway capacity after sagittal compression.
    American journal of orthodontics and dentofacial orthopedics: official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 09/2010; 138(3):292-9. · 1.33 Impact Factor
  • Source
    Article: Improved correlation between CT emphysema quantification and pulmonary function test by density correction of volumetric CT data based on air and aortic density.
    Song Soo Kim, Joon Beom Seo, Namkug Kim, Eun Jin Chae, Young Kyung Lee, Yeon Mok Oh, Sang Do Lee
    [show abstract] [hide abstract]
    ABSTRACT: OBJECTIVES: To determine the improvement of emphysema quantification with density correction and to determine the optimal site to use for air density correction on volumetric computed tomography (CT). METHODS: Seventy-eight CT scans of COPD patients (GOLD II-IV, smoking history 39.2±25.3 pack-years) were obtained from several single-vendor 16-MDCT scanners. After density measurement of aorta, tracheal- and external air, volumetric CT density correction was conducted (two reference values: air, -1000HU/blood, +50HU). Using in-house software, emphysema index (EI) and mean lung density (MLD) were calculated. Differences in air densities, MLD and EI prior to and after density correction were evaluated (paired t-test). Correlation between those parameters and FEV(1) and FEV(1)/FVC were compared (age- and sex adjusted partial correlation analysis). RESULTS: Measured densities (HU) of tracheal- and external air differed significantly (-990±14, -1016±9, P<0.001). MLD and EI on original CT data, after density correction using tracheal- and external air also differed significantly (MLD: -874.9±27.6 vs. -882.3±24.9 vs. -860.5±26.6; EI: 16.8±13.4 vs. 21.1±14.5 vs. 9.7±10.5, respectively, P<0.001). The correlation coefficients between CT quantification indices and FEV(1), and FEV(1)/FVC increased after density correction. The tracheal air correction showed better results than the external air correction. CONCLUSION: Density correction of volumetric CT data can improve correlations of emphysema quantification and PFT.
    European journal of radiology 05/2012; · 2.65 Impact Factor
  • Source
    Article: Panoramic endoluminal display with minimal image distortion using circumferential radial ray-casting for primary three-dimensional interpretation of CT colonography
    Seung Soo Lee, Seong Ho Park, Jin Kook Kim, Namkug Kim, Jeongjin Lee, Beom Jin Park, Young Jun Kim, Min Woo Lee, Ah Young Kim, Hyun Kwon Ha
    [show abstract] [hide abstract]
    ABSTRACT: The purpose of this study was to develop a panoramic endoluminal display technique, the band view, which causes minimal image distortion, and to determine its feasibility as a time-efficient primary three-dimensional review method of CT colonography (CTC). Image distortion was compared between the band view and four other three-dimensional review modes using ten 10-mm and ten 20-mm electronically generated polyps. Diagnostic performance and interpretation time were compared between the band view and the conventional endoluminal view by two independent readers in 52 patients who underwent CTC and colonoscopy on the same day. Mean image distortion index values, in which 1 indicates no distortion and the larger value represents greater distortion, were significantly smaller with the band view (1.03 and 1.01 for 10-mm and 20-mm polyps, respectively) than with the filet view (1.65 and 1.55) or the virtual colon dissection (3.27 and 3.85) (P ≤ 0.004). The sensitivity and specificity for detecting adenomatous polyps ≥6mm did not differ, but the mean interpretation time was significantly shorter with the band view than with the conventional endoluminal view by 1.8 and 4.5 minutes in readers 1 and 2, respectively (P < 0.0001). The band view can be a time-efficient alternative for primary three-dimensional review of CTC.
    European Radiology 04/2012; 19(8):1951-1959. · 3.22 Impact Factor

About

Assistant Research Professor (Appointment), Dept. of Radiology, University of Ulsan College of Medicine, Asan Medical Center (2010.04 - )

RESEARCH INTERESTS:
* Scientific methodology, Governmental Strategic Planning, etc
* Robotic interventions: Computer Assisted Surgery, Navigation, Surgical Robot
* Medical Image Processing: Segmentation & Registration, MR Physics
* Developing Imaging Biomarkers: DWI/DTI/fMRI/meMRI, Treatment Response Analysis
* Animal imaging

Following (40) See all

Followers (42) See all

Browse more researchers