mohamed-Elbagir Ahmed

Publications (7) View all

• Article: The changing pattern of upper gastro-intestinal lesions in southern Saudi Arabia: an endoscopic study.

  Sulieman M Al-Humayed, Ahmed K Mohamed-Elbagir, Abdelhamid A Al-Wabel, Yahya A Argobi
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  ABSTRACT: Dyspepsia is a common gastrointestinal disorder and is the most common indication for upper gastrointestinal endoscopy (UGIE). In recent years, it has been observed in several centers that there is a change in the causes of dyspepsia as revealed by UGIE. Our main objectives were: (1) To study the pattern of upper gastrointestinal pathology in patients with dyspepsia undergoing upper endoscopy; (2) Compare that with the pattern seen 10-15 years earlier in different areas of KSA. Retrospective study of all UGI endoscopies performed at Aseer Central Hospital, Abha, Southern Saudi Arabia during the years 2005-2007 on patients above 13 years of age. Patients who underwent UGIE for reasons other than dyspepsia were excluded. The analysis was performed using the SPSS 14 statistical package. A total of 1,607 patients underwent UGI endoscopy during the three-year study period (age range, 15-100). There were 907 males (56.4%) and 700 female (43.6%). Normal findings were reported on 215 patients (14%) and the majority had gastritis (676 = 42%), of whom 344 had gastritis with ulcer disease. Moreover, 242 patients (15%) had gastro-esophageal reflux (GERD), with or without esophagitis or hiatus hernia. Also, a total of 243 patients had duodenal ulcer (DU) (15%) while only 12 had gastric ulcer (0.7%). There is clear change in the frequency of UGIE lesions detected recently compared to a decade ago with an increasing prevalence of reflux esophagitis and hiatus hernia. This could be attributed to changes in lifestyle and dietary habits such as more consumption of fat and fast food, increased prevalence of obesity, and smoking. These problems should be addressed in order to minimize the serious complications of esophageal diseases.
  Saudi Journal of Gastroenterology 01/2010; 16(1):35-7.
• Article: Comparison of 4 laboratory methods for detection of Helicobacter pylori.

  Sulieman M Al-Humayed, Mohamed Elbagir K Ahmed, Cornelius S Bello, Mar'I A Tayyar
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  ABSTRACT: To compare the usefulness of 4 commonly used tests in the diagnosis of Helicobacter pylori H. pylori infection in Saudi patients with dyspepsia. Patients presenting with dyspepsia at the gastroenterology clinic of Aseer Central Hospital, Abha, Kingdom of Saudi Arabia between October 2005 to May 2006, who consented to participate in the study were enrolled. Patients who received anti-Helicobacter treatment or proton pump inhibitors within 30 days, or in whom endoscopy revealed cancer or gastro-esophageal reflux, were excluded from the study. Stool sample for H. pylori stool antigen HpSA were tested using the enzyme immunoassay technique 2-7 days before endoscopy. At endoscopy, gastric antrum mucosal biopsies were taken for campylobacter-like organism CLO test, histology and culture. There were 72 males and 43 females, age range from 18-75 years, mean age 40.09+/-15.68. Seventy-nine patients out of the 115 68.7% samples were positive for H. pylori, by culture. Culture and histology agreed in 112 cases 97.4% and disagreed in 3 cases 2.6%. The sensitivities and specificities % of histology were 97.5 and 97.2, of HpSAg were 91.9 and 98.6, and of CLO were 79.7 and 97.2 tests against culture. Culture, histology, and H. pylori stool antigen tests all have comparable results, and there is no need to use all 3 at the same time, for the diagnosis of H. pylori infection. The CLO test is less sensitive, and of low negative predictive value.
  Saudi medical journal 05/2008; 29(4):530-2. · 0.52 Impact Factor
• Article: Systemic toxicity of para-phenylenediamine.

  E H El-Ansary, M E Ahmed, H W Clague
  The Lancet 07/1983; 1(8337):1341. · 38.28 Impact Factor
• Article: Personal View

  M E K Ahmed
• Article: Cefotetan (Cefotan): a new cephalosporin.

  M E Ahmed, G May, R A Branch
  Rational drug therapy 01/1987; 20(12):1-5.