Misbah Khan

Weill Cornell Medical College | Cornell · Department of Dermatology

Background Cryolipolysis is a fairly popular procedure performed in North America, Europe, and many other countries. Although it is considered a rather safe procedure, there are, however, underreported side effects such as paradoxical adipose hyperplasia (PAH), contour irregularities, skin and soft tissue atrophy, and asymmetries. Our knowledge reg...

Importance During Mohs micrographic surgery of nonmelanoma skin cancer (NMSC), inflammation in histologic frozen sections has been found to occasionally presage the detection of tumors in frozen sections of adjacent excision specimens.Objective To quantify the correlation between the location of inflammation without visible tumor in histologic fr...

Importance Keratosis pilaris (KP) is a common skin disorder of follicular prominence and erythema that typically affects the proximal extremities, can be disfiguring, and is often resistant to treatment. Shorter-wavelength vascular lasers have been used to reduce the associated erythema but not the textural irregularity.Objective To determine whe...

Tumescent liposuction (TL) is one of the most commonly performed cosmetic surgeries in the United States. Although liposuction is not a therapy for obesity, it can be used to create a more aesthetic silhouette for a given body shape. Tumescent liposuction allows for the removal of large volumes of fat with minimal blood loss, low postoperative morb...

Body contouring or soi-disant Liposculpting is an effective method for surgically improving localized subcutaneous areas of adiposity. The idea of removing excess fat from skin is not new [1]. In 1921 Charles Dujarrier, in France, attempted to remove subcutaneous fat using a uterine curette on a dancer’s calves and knees. A tragic result occurred d...

A better understanding of the molecular pathways that characterize cell growth, apoptosis, angiogenesis, and invasion has provided novel targets in cancer therapy. Epidermal growth factor receptor (EGFR)-mediated signal transduction has been one of the most studied pathways in carcinogenesis. The phosphorylation of EGFR activates multiple biologica...

The authors have indicated no significant interest with commercial supporters.

Context Repeated patient education about skin cancer prevention is important to self-care after transplant. Objective Examine educational materials for kidney transplant recipients available on the Internet that address sun protection and skin self-examination for early detection of squamous cell carcinoma. Design Systematic review of Web sites f...

Repeated patient education about skin cancer prevention is important to self-care after transplant. Examine educational materials for kidney transplant recipients available on the Internet that address sun protection and skin self-examination for early detection of squamous cell carcinoma. Systematic review of Web sites for kidney transplant recipi...

Cellulite is a multifactorial condition that is present in 80% to 90% of postpubertal women and is one of the most intolerable esthetic imperfections. There are several theories on the pathophysiology of cellulite, and a number of different therapeutic regimens have been developed, from topical treatments to mechanical or energy-based devices. In t...

Cellulite is a topographic skin change that is nearly ubiquitous in postpubertal women. Treatment remains elusive. The various treatments currently available are only partially or temporarily effective. Newer therapeutic modalities continue to evolve without much understanding of the complex nature of cellulite. The successful treatment of cellulit...

Treatments for localized adiposities range from topical creams to liposuction. Most treatments lack a substantial proof of efficacy. The unpredictable treatment outcome can be related to the fact that cellulite adipose tissue is physiologically and biochemically different from subcutaneous tissue found elsewhere in the body. Part II of this two-par...

An 8-year-old Caucasian girl presented with a linear patch of excessive hair growth involving her left posterolateral leg without any underlying hypopigmentation or associated abnormalities. This is an unusual presentation given that the literature describing nevoid hypertrichosis in a linear distribution is associated with either underlying skin o...

Laser resurfacing of facial rhytids has become a popular treatment for many patients who have wrinkles, photodamage, and acne scarring. Erbium:YAG laser resurfacing has emerged as one of the safer, more effective methods of facial rejuvenation and its increasing popularity has led to its widespread use for resurfacing. However, size and high initia...

Port-wine stain (PWS) birthmarks are congenital, low-flow vascular malformations of the skin. Lasers are the modality of choice for the treatment of PWS birthmarks, and for most patients the pulsed-dye laser in conjunction with epidermal cooling offers the greatest efficacy and safety. Other light devices, including the 532-nm frequency-doubled Nd:...

Background and Objectives To produce controlled, spatially confined thermal effects in dermis.Study Designs/Materials and MethodsA 1 W, 1,500 nm fiber-coupled diode laser was focused with a high numerical aperture (NA) objective to achieve a tight optical focus within the upper dermis of skin held in contact with a glass window. The delivery optics...

Human skin prepared with an optical clearing agent manifests reduced scattering as a result of de-hydration and refractive index matching. This has potentially large effects for laser therapies of several skin lesions such as port wine stain, hair removal and tattoo removal. With most topically applied clearing agents the clearing effect is limited...