Md. Nur Kabidul Azam

Publications (18) View all

• Conference Proceeding: Medicinal Plants used in Treatment of Tumors: Results from a Survey of Folk Medicinal Practitioners in two Randomly SelectedVillages in Khulna and Bagerhat Districts, Bangladesh.

  Md. Nazmul Hasan, Md. Nasir Ahmed, Md. Zobaer Ahmed Bhuiyan, Md. Mizanur Rahman, M.N.K. Azam, Mohammed Rahmatullah
  An International Conference on Green Chemistry for Sustainable Development, Jessore Science & Technology University, Jessore, Bangladesh; 07/2012
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  Available from: Md. Nur Kabidul Azam

  Article: Antihyperglycemic activity Evaluation of Rhizomes of Curcuma zedoaria (Christm.) Roscoe and Fruits of Sonneratia caseolaris (L.)Engl.

  Mohammed Rahmatullah, Md. Nur Kabidul Azam, Sujan Pramanik, Sania, Shahnaz Rahman, Rownak Jahan
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  ABSTRACT: Diabetes is a debilitating disease affecting millions of people worldwide for which allopathic medicine has no known complete cure. Since the disease is projected to rise, significant scientific interest has focused on the plant kingdom towards discovery of newer anti-hyperglycemic drugs. The objective of the present research was to evaluate in oral glucose tolerance tests, the anti-hyperglycemic potential of methanol extract of Curcuma zedoaria rhizomes and fruits of Sonneratia caseolaris, both of which are used as anti-diabetics in the folk medicinal system of Bangladesh. Methanolic extract of rhizomes, when orally administered to glucose-loaded mice significantly and dose-dependently reduced concentrations of serum glucose. At extract doses of 50, 100, 200 and 400 mg per kg body weight serum glucose concentrations were reduced by, respectively, 36.9, 39.4, 41.1 and 55.1%. In comparison, a standard anti-hyperglycemic drug, glibenclamide reduced serum glucose concentration by 63.9% at a dose of 10 mg per kg body weight. Methanol extract of fruits also significantly and dose-dependently reduced serum glucose concentrations following administration, but the percent reductions were less than that obtained with rhizomes. At same doses of extract, serum glucose concentrations were reduced by 19.3, 27.6, 28.6 and 41.4%, respectively. The demonstrated anti-hyperglycemic activities by rhizomes of C. zedoaria and fruits of S. caseolaris validate their folk medicinal uses and warrants further studies towards elucidation of responsible phytochemical components, which can be potentially more efficacious drugs for treatment of diabetes.
  International Journal of PharmTech Research. 03/2012; 4(1-CODEN (USA): IJPRIF ISSN : 0974-4304):125-129.
• Article: An Ethnomedicinal Survey among the Marakh Sect of the Garo Tribe oF Mymensingh District, Bangladesh

  Mohammed Rahmatullah, Md. Nur Kabidul Azam, Ishita Malek, Dilruba Nasrin, Farhana Jamal, Md. Atiqur Rahman, Zubaida Khatun, Sharmin Jahan, Syeda Seraj, Rownak Jahan
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  ABSTRACT: The Garos are one of the largest ethnic groups of Bangladesh residing in the north central districts of Tangail, Mymensigh, Netrakona, Gazipur and Sherpur of the country. Although in recent years, the Garos are rapidly converting to Christianity and intermingling with the majority Bengali-speaking population, they still, to some extent, preserve their own cultural identities including their language and traditional medicinal practices and quite often reside in villages separate from the mainstream population. The Garo traditional medicinal practitioners are reputed to possess considerable knowledge of medicinal plants, a knowledge which has been accumulated over centuries through practices and usages. The objective of the present study was to conduct an ethnomedicinal survey among the Garo traditional practitioners of two villages, namely Kal Shindu and Monca Para in Mymensingh district of Bangladesh. Notably, both villages were inhabited solely by the Garos and who still maintained their traditional culture and practices. After obtaining informed consent from the practitioners, interviews were conducted with the help of a semi-structured questionnaire and the guided field-walk method. A total of 46 medicinal plants distributed into 34 families were observed to be used by the practitioners. The Fabaceae family contributed four plants followed by the Lamiaceae and the Moraceae family with three plants each. Leaves were the major plant part used followed by fruits. The various ailments treated by the Garo practitioners included gastrointestinal disorders, respiratory tract disorders, hepatic disorders, cancer, diabetes, fever, wounds, cholera, sexually transmitted diseases, helminthiasis, rheumatism, piles, leprosy, hemorrhoids, menstrual problems, urinary disorders, chicken pox, skin problems and sexual disorders. Traditional medicinal knowledge of indigenous peoples has led to discovery of many modern drugs; from that view point, the medicinal plants of the Garos warrant further scientific studies.
  International Journal of PharmTech Research 03/2012; 4(1-CODEN (USA): IJPRIF ISSN : 0974-4304):141-149.
• Article: MEDICINAL PLANTS USED FOR TREATMENT OF DIABETES BY THE MARAKH SECT OF THE GARO TRIBE LIVING IN MYMENSINGH DISTRICT, BANGLADESH

  Mohammed Rahmatullah, Md. Nur Kabidul Azam, Zubaida Khatun, Syeda Seraj, Farhana Islam, Md. Atiqur Rahman, Sharmin Jahan, Md. Shah Aziz, Rownak Jahan
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  ABSTRACT: Diabetes mellitus is an endocrinological disorder arising from insulin deficiency or due to ineffectiveness of the insulin produced by the body. This results in high blood glucose and with time, to neurological, cardiovascular, retinal and renal complications. It is a debilitating disease and affects the population of every country of the world. Around 200 million people of the world suffer from this disease and this figure is projected to rise to 300 million in the coming years. The disease cannot be cured with allopathic medicine as the drugs used do not restore normal glucose homeostasis and moreover have side-effects. On the other hand, traditional medicinal practitioners of various countries claim to cure diabetes or at least alleviate the major symptoms and progression of this disease through administration of medicinal plants. The Garos are an indigenous community of Bangladesh, who still follow their traditional medicinal practices. Their traditional medicinal formulations contain a number of plants, which they claim to be active antidiabetic agents. Since observation of indigenous practices have led to discovery of many modern drugs, it was the objective of the present study to conduct a survey among the Marakh sect of the Garos residing in Mymensingh district of Bangladesh to find out the medicinal plants that they use for treatment of diabetes. It was found that the tribal practitioners of the Marakh sect of the Garos use twelve medicinal plants for treatment of diabetes. These plants were Lannea coromandelica, Alstonia scholaris, Catharanthus roseus, Enhydra fluctuans, Terminalia chebula, Coccinia grandis, Momordica charantia, Cuscuta reflexa, Phyllanthus emblica, Syzygium aqueum, Drynaria quercifolia, and Clerodendrum viscosum. A review of the scientific literature demonstrated that almost all the plants used by the Garo tribal practitioners have reported antidiabetic and/or antioxidant properties and have enormous potential for possible development of new and efficacious antidiabetic drugs. Full Text: FULLTEXT.PDF
  African Journal of Traditional, Complementary and Alternative medicines (AJTCAM), Vol 9, No 3 (2012). 03/2012; 9(3-AJTCAM ISSN: 0189-6016).
• Article: IN VITRO SEEDS GERMINATION AND PLANTLETS DEVELOPMENT OF SILVIUS APPENDICULATUS (Orchidaceae)

  M.N. HASAN, A. ANSARI, M.S.Z. SHAHRIAR, M.N.K. AZAM, S..M.A. AWAL
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  ABSTRACT: Hasan MN, Ansari A, Shahriar MSZ, Azam MNK, Awal SMA (2011) In vitro seeds germination and plantlets development of Silvius appendiculatus (Orchidaceae). Int. J. Sustain. Crop Prod. 6(2), 1-5. Bangladesh is rich in orchids, with 159 species and two varieties under 63 genera (Huda et al.1999). These species are distributed mainly in the hilly areas of greater Sylhet, Chittagong and Mymensingh districts. Seeds of S. appendiculatus were germinated successfully and grew well in the in vitro culture. The best medium were observed for germinating the S. appendiculatus seeds, viz. Knudson-C (KnC) basal medium supplemented with 30% (v/v) maturity coconut water/milk (CW). All the seeds were observed those overall germination, protocorms formation and seedling development (about 100%). The best medium for growing and development of seedlings to become fully expanded plantlets was determined half strength of Murashige and Skoog (1/2MS) medium supplemented with 40% (v/v) CW. The plantlets of S. appendiculatus were resulted from these research approximately more than 2000 individuals. The fully expanded seedlings were transferred to perforated plastic pots and grow in the screen house.
  International Journal of Sustainable Crop Production (IJSCP). 01/2011; Volume: 6:1-5.