A1- Research for new RIPs (purification and characterization); A2- Studies on distribution and physiological role of RIPs; A3- Mechanisms of RIP cytotoxicity.
B1- Design and construction of new immunotoxins, obtained through chemical modification and conjugation of the components, to obtain specific drugs to target cells responsible for pathological conditions; B2- In vitro and in vivo studies on immunotoxins for the experimental therapy of tumors, GVHD and graft rejection.

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