Johannes W. Dietrich
Ruhr-Universität Bochum · Laboratory XU44, Bergmannsheil University Hospitals
Internal Medicine (General Medicine), Endocrinology, Diabetology, Biostatistics, Bioinformatics, Applied Mathematics
142Impact points
22Publications
104Followers
Research Experience
Education
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Journal of Mathematical Biology
Nature Reviews Endocrinology
Epidemiologie (GMDS), Gesellschaft für Medizinische Ausbildung (GMA), European Society of Endocrinology, Gesellschaft
für Kybernetik, Tudmonda Asocio pri Kibernetiko, Informadiko kaj Sistemiko (TAKIS), Internationaler
Wissenschaftlerkreis (ISK) der Internationalen Akademie der Wissenschaften (AIS) San Marino
Diabetes/Metabolism Research and Reviews
Hormone and Metabolic Research
Journal of Clinical Gastroenterology
Publications
The proteomic signature of insulin-resistant human skeletal muscle reveals increased glycolytic and decreased mitochondrial enzymes
Diabetologia. 55.
Aims/hypothesis The molecular mechanisms underlying insulin resistance in skeletal muscle are incompletely understood. Here, we aimed to obtain a global picture of changes in protein abundance in
The parathyroid as a target for radiation damage.
The New England journal of medicine. 365(7):676-8.
Protection from diabetes development by single-chain antibody-mediated delivery of a NF-{kappa}{kappa}B inhibitor specifically to {beta}{beta}-cells in vivo.
American journal of physiology. Endocrinology and metabolism.
Recently, we reported the generation of single-chain antibodies (SCAs) highly specific for rodent and human β-cells. Our current report describes the generation of a fusion protein of one of these
Normal values for longitudinal function of the right ventricle in healthy women >70 years of age.
European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology.
AIMS: The application of tricuspid annular plane systolic excursion (TAPSE) as an additional echocardiographic tool to analyse right ventricular (RV) systolic function has been recently established
In vitro phage display in a rat beta cell line: a simple approach for the generation of a single-chain antibody targeting a novel beta cell-specific epitope.
Diabetologia.
AIMS/HYPOTHESIS: The aim of the present study was to evaluate in vitro phage display in a beta cell line as a novel strategy for the isolation of beta cell-specific agents/biomarkers. METHODS: A
Generation of novel single-chain antibodies by phage-display technology to direct imaging agents highly selective to pancreatic {beta}- or {alpha}-cells in vivo.
Diabetes.
Objective: Non-invasive determination of pancreatic beta-cell mass in vivo has been hampered by the lack of suitable beta-cell specific imaging agents. This report outlines an approach for the
Thyroid examination in highly radiation-exposed workers after the Chernobyl accident.
European journal of endocrinology / European Federation of Endocrine Societies.
Context: Radioactive contamination from the Chernobyl nuclear accident which happened in the morning of 26 April 1986 had a major impact on thyroid health in the Belarus region. Objective:
The AQUA-FONTIS Study: Protocol of a multidisciplinary, cross-sectional and prospective longitudinal study for developing standardized diagnostics and classification of non-thyroidal illness syndrome.
BMC endocrine disorders. 8(1):13.
ABSTRACT: BACKGROUND: Non-thyroidal illness syndrome (NTIS) is a characteristic functional constellation of thyrotropic feedback control that frequently occurs in critically ill patients. Although
[Absorption, transport and bio-availability of iodothyronines].
Deutsche medizinische Wochenschrift (1946). 133(31-32):1644-8.
The frequently prescribed classical thyroid hormones (iodothyronines) are critical dose drugs with a narrow therapeutic index. Nowadays the mechanisms of their absorption, which takes place
Iodothyronine antibodies are not correlated with prevalence or prognosis of non-thyroidal illness syndrome
European Congress of Endocrinology 2008;
Patients suffering from critical illness usually exhibit a characteristic functional state of thyrotropic feedback control that is referred to as non-thyroidal illness syndrome (NTIS). Today, there
Thyroxine in goiter, H. pylori infection, and gastritis.
The New England journal of medicine. 355(11):1177; author reply 1177.
Absorption kinetics of levothyroxine is not altered by proton-pump inhibitor therapy.
Hormone and metabolic research. Hormon- und Stoffwechselforschung. Hormones et métabolisme. 38(1):57-9.
Thyrotropic Feedback Control: Evidence for an Additional Ultrashort Feedback Loop from Fractal Analysis
Cybernetics and Systems. 35:315-31.
More than 70 years after the discovery of the pituitary thyroid feedback control mechanism, a classical endocrine regulation system, most of its parameters have been identified. However, the
Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
The Journal of clinical endocrinology and metabolism. 87(4):1687-91.
In areas with severe selenium deficiency there is a higher incidence of thyroiditis due to a decreased activity of selenium-dependent glutathione peroxidase activity within thyroid cells.
Der Hypophysen-Schilddrüsen-Regelkreis: Entwicklung und klinische Anwendung eines nichtlinearen Modells
Degree: Dr. med.
Supervisor: Prof. Dr. rer. nat. Dr. med. habil. Ulla Mitzdorf
Following
Bernt-Dieter Huismans
http://www.aerzte-borreliose-augsbu...
Shishir Gupta
Universität Heidelberg
René Schenkendorf
Max Planck Institute for Dynamics...
Egberto Gaspar de Moura
Universidade do Estado do Rio de...
Subhrojit Sen
University of Western Ontario
Topics

Academic Degrees
Dr.
Research Keywords
Thyroid, Type 2 Diabetes, Glia, Insulin Signaling, Pascal Programming, Myelin, Biomedical Cybernetics, R, Mathematical Biology, Amiodarone, Cerebrospinal Fluid, Cybernetics, Demyelinating Diseases, Insulin Resistance, Parathyroid Hormone, Thyroid Diseases, Thyroid Function Tests, Thyroid Gland, Mitochondrial Diseases, Proteomics, Insulin Receptor Substrate Proteins, NTIS, Non-Thyroidal Illness Syndrome, Hypodeiodation, Hyperdeiodation, High-T3 syndrome, HOMA, Structure Parameter Inference Approach, Control Theory in Life Sciences, Deiodinases, Hyperdeiodination, Hypodeiodination, calcium homeostasis, computational statistics
Past Advisors
Ulla Mitzdorf, Renate Pickardt, Roland Gärtner, Bernhard O. Böhm, Ulrich Loos, Steffen Hering, Horst Mittelstaedt
Current Location
Bochum, Germany