Johan Fredrik Skomsvoll

Publications (35) View all

• Article: Pregnancy and delivery in women with chronic inflammatory arthritides with a specific focus on first birth.

  Marianne Wallenius, Johan F Skomsvoll, Lorentz M Irgens, Kjell Å Salvesen, Bjorn Y Nordvåg, Wenche Koldingsnes, Knut Mikkelsen, Cecilie Kaufmann, Tore K Kvien
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  ABSTRACT: To examine possible associations between chronic inflammatory arthritides and pregnancy outcomes with separate analyses of first and subsequent births before and after diagnosis. Linkage of data from a registry of patients with chronic inflammatory arthritides and the Medical Birth Registry of Norway enabled a comparison of pregnancy outcomes in women with chronic inflammatory arthritides and pregnancy outcomes in reference subjects. Outcomes of first birth and subsequent births before and after diagnosis were analyzed separately. Associations between chronic inflammatory arthritides and the women's health during pregnancy and delivery as well as perinatal outcomes were assessed in logistic regression analyses with adjustments for maternal age at delivery and gestational age. We analyzed 128 first births and 151 subsequent births after diagnosis and 286 first births and 262 subsequent births before diagnosis in patients and compared them with first and subsequent births in reference subjects. Firstborn children of women diagnosed as having chronic inflammatory arthritides were more often preterm (odds ratio [OR] 1.85 [95% confidence interval (95% CI) 1.09-3.13]) and small for gestational age (OR 1.60 [95% CI 1.00-2.56]). They also had lower mean birth weight (P=0.01) and higher perinatal mortality (OR 3.26 [95% CI 1.04-10.24]). Birth by caesarean section (all classifications) was more frequent in patients than in reference subjects, and elective caesarean section was 2-fold more frequent in patients, both in first birth (OR 2.60 [95% CI 1.43-4.75]) and in subsequent births (OR 2.18 [95% CI 1.33-3.58]). No excess risks of clinical importance were observed prior to diagnosis of chronic inflammatory arthritides. Excess risks were related to first birth in women diagnosed as having chronic inflammatory arthritides, including a higher rate of perinatal mortality. A higher caesarean section rate was related to all patient deliveries. Mainly, pregnancy outcomes before diagnosis did not differ from those in reference subjects.
  Arthritis & Rheumatism 06/2011; 63(6):1534-42. · 7.87 Impact Factor
• Article: Fertility in women with chronic inflammatory arthritides.

  Marianne Wallenius, Johan F Skomsvoll, Lorentz M Irgens, Kjell Å Salvesen, Bjorn-Yngvar Nordvåg, Wenche Koldingsnes, Knut Mikkelsen, Cecilie Kaufmann, Tore K Kvien
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  ABSTRACT: To compare fertility rates in women with RA, other chronic arthritides (OCAs) and JIA with reference women from the general population. Each woman from a Norwegian patient registry was matched by year of birth with 100 reference women randomly selected from the National Population Registry. Data linkage of patients and references with the Medical Birth Registry of Norway (MBRN) identified all offspring in patients and references until October 2007, and indirectly also nulliparous (childless) women. Groups were compared with Mann-Whitney U-test for continuous variables and chi-squared tests for categorical variables. Poisson regression analysis was applied to calculate relative fertility rates in the diagnostic groups vs references. Among 631 patients 849 children were registered in MBRN. Of these, 289 children (34.0%) were born after time of diagnosis vs 44.3% in references. Altogether, 206 of 631 patients (32.6%) were nulliparous vs 26.4% in references (P < 0.001). Among RA patients, 28.4% (96 of 338) were nulliparous vs 24.5% in references (P = 0.09), 30.7% (67 of 218) in OCA patients vs 24.5% in references (P = 0.03) and 57.3% (43 of 75) in JIA patients vs 40.9% in references (P = 0.004). Adjusted relative fertility rates in RA, OCA and JIA after diagnosis were 0.88, 0.84 and 0.84, respectively, compared with references. A higher proportion of women with chronic inflammatory arthritides were nulliparous compared with references, and relative fertility rates were reduced in all patient groups.
  Rheumatology (Oxford, England) 02/2011; 50(6):1162-7. · 4.24 Impact Factor
• Source

  Available from: Lillian Reinseth

  Article: Performance in leisure-time physical activities and self-efficacy in females with rheumatoid arthritis.

  Lillian Reinseth, Till Uhlig, Ingvild Kjeken, Hege Svean Koksvik, Johan Fredrik Skomsvoll, Geir Arild Espnes
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  ABSTRACT: The purpose of this study was to examine leisure-time physical activities (LTPAs) and their association with self-efficacy in females with rheumatoid arthritis (RA) (n = 238). Their self-reported performance in LTPAs was measured by the Interest Checklist and efficacy beliefs by using the Arthritis Self-Efficacy Scales (ASES). LTPAs were classified as active or less active according to how many LTPAs they performed. The participants had reduced their participation in LTPAs by almost one-third during the last year. Active individuals performed the vigorous activities more often, they had a higher level of education, were working to a significantly greater extent, and reported better function, higher scores on the self-efficacy scales, and lower joint pain and fatigue. Multivariate analyses demonstrated that a high level of LTPAs was independently related to less fatigue (OR 0.98, p = 0.004), positive self-efficacy in coping with RA functions (OR 1.03, p = 0.015), and higher employment level (OR 0.42, p = 0.039). Only a quarter of the responders were physically active in their leisure time in the present study. Less active individuals reduced their performance in LTPAs to a much higher degree than active individuals during the last year. Partaking in a high amount of LTPAs was related to less fatigue and higher efficacy beliefs.
  Scandinavian Journal of Occupational Therapy 09/2011; 18(3):210-8. · 1.07 Impact Factor
• Article: A 50-year-old man with eosinophilia and cardiomyopathy: need for endomyocardial biopsy?

  Lars Aakerøy, Brage Høyem Amundsen, Johan Fredrik Skomsvoll, Bjørn Olav Haugen, Johannes Soma
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  ABSTRACT: A 50-year-old man was admitted with a suspected acute coronary syndrome. The coronary angiogram, however, was normal. He was found to have a cardiomyopathy and eosinophilia. The diagnosis was established as a perimyocarditis secondary to the Churg-Strauss syndrome. An important question is whether an endomyocardial biopsy should have been performed.
  European Heart Journal – Cardiovascular Imaging 12/2010; 12(3):257-9. · 2.32 Impact Factor
• Article: Parity in patients with chronic inflammatory arthritides childless at time of diagnosis.

  M Wallenius, J F Skomsvoll, L M Irgens, K Å Salvesen, B-Y Nordvåg, W Koldingsnes, K Mikkelsen, C Kaufmann, T K Kvien
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  ABSTRACT: To assess parity in women with chronic inflammatory arthritides (CIA) childless at time of diagnosis. Patients were selected from the Norwegian Disease-Modifying Anti-Rheumatic Drug (NOR-DMARD) registry. Each patient was matched by year of birth with 100 reference women from the Norwegian Population Registry. Data linkage for patients and references with the Medical Birth Registry of Norway (MBRN) identified all offspring until time of linkage (October 2007). Patients and corresponding references childless at the time of diagnosis were included in the analyses. Kaplan-Meier curves visualized the proportion of childless women and were compared by a log rank test. In all, 156 rheumatoid arthritis (RA), 107 other chronic arthritides (OCA), and 75 juvenile idiopathic arthritis (JIA) patients were childless at time of diagnosis. At the time of data linkage, the proportions (%) of childless RA/OCA/JIA patients versus references were 61.5/62.6/57.3 versus 46.9/42.9/41.0, respectively, all differences statistically significant. The log rank test showed lower parity in all diagnostic groups compared with references (p < 0.001 for RA and OCA and p = 0.002 for JIA). No difference in parity was observed between RA and OCA patients, but both diagnostic groups had lower parity than JIA patients (p = 0.001). Disease characteristics were similar between childless and fertile patients. Reduced parity was observed in all diagnostic groups compared with references. RA and OCA patients had lower parity than JIA patients, indicating that having the disease as a young adult may influence parity more than having the disease in childhood.
  Scandinavian journal of rheumatology 02/2012; 41(3):202-7. · 2.51 Impact Factor