Publications (21) View all
-
Article: Osteomedullography in estimating the consolidation of long bone fractures in the dog
[show abstract] [hide abstract]
ABSTRACT: Six canine long bone fractures with delayed or non-union were investigated using osteomedullography. The contrast medium crossed the fracture (positive osteomedullography) in four cases. All contrast medium remained in the distal fragment (negative osteomedullography) in two cases. The fractures with the negative finding were operated upon using bone grafts. Conservative fracture treatment using transfixation or plaster cast was continued in the positive cases. All the fractures united from 9 to 15 weeks after the examination and treatment. Osteomedullography proved to be a reliable method for identifying which non-union fractures require further operative treatment for healing.Journal of Small Animal Practice 06/2008; 23(8):445 - 450. · 1.00 Impact Factor -
Article: Real‐time ultrasound pregnancy diagnosis in the bitch
[show abstract] [hide abstract]
ABSTRACT: ABSTRACTA portable real-time ultrasound scanner was used for pregnancy diagnosis in eight bitches. Pregnancy was detected in seven; one bitch was not pregnant. The period between the 28th and 35th days of gestation seemed to be the most suitable time for counting the foetuses. Details of the foetal bodies were clearly visible after the 40th day of pregnancy. Most of the foetuses were detected. Real-time ultrasound can be used for the diagnosis of canine pregnancy as a safe, rapid and easy method, although some inaccuracy in foetal count exists.Journal of Small Animal Practice 04/2008; 24(3):145 - 151. · 1.00 Impact Factor -
Article: Tissue response to a braided poly-L-lactide implant in an experimental reconstruction of anterior cruciate ligament
[show abstract] [hide abstract]
ABSTRACT: During follow-up periods of 6, 12, 24 and 48 weeks, the tissue response to a braided poly-L-lactide (PLLA) implant, 3.2 mm in diameter, was investigated in the reconstruction of experimental anterior cruciate ligament (ACL) ruptures in 32 sheep. In 16 sheep the cut ACL was removed and reconstructed with the fascia lata augmented with a PLLA implant. In 16 sheep the ACL was cut from its midportion, sutured, and thereafter augmented with a PLLA implant. The tissue reactions were typical of a scant non-specific-foreign-body reaction. The number of inflammatory and giant cells was greatest at six weeks, decreasing thereafter. Degradation of the PLLA was incomplete at 48 weeks. No signs of synovitis or changes in the cartilaginous surfaces were observed. The reconstructions in both groups were anchored to the bone by fibroconnective tissue, and remodelling of the bone was seen along the drill channels. After 48 weeks the maturation of the fibroconnective tissue and the orientation of the collagen fibres were higher (pJournal of Materials Science Materials in Medicine 11/1993; 4(6):547-554. · 2.32 Impact Factor -
Article: Tick-borne encephalitis virus in ticks in Finland, Russian Karelia and Buryatia.
[show abstract] [hide abstract]
ABSTRACT: Tick-borne encephalitis (TBE) is a central nervous system infection caused by a flavivirus [tick-borne encephalitis virus (TBEV)], transmitted by Ixodes ticks and endemic in a large region in Eurasia. We collected 2411 ticks from Finland and Russia in 2003-2008, screened them for TBEV by RT-PCR and isolated and analysed eight strains belonging to all three TBEV subtypes; in addition, we obtained two European-subtype strains from human serum samples. TBEV RNA prevalence in unengorged ticks was approximately 1 % both in the northernmost TBE-endemic areas of Europe in Finland and Russian Karelia, and in Siberia in Buryatia. In Finland, both Ixodes ricinus and Ixodes persulcatus ticks were found from distinct areas and, in Russian Karelia, were overlapping in the same study site. TBEV E and NS3 gene sequences obtained showed a variability of 0-4 % within European-subtype strains, 2-9 % for Siberian-subtype strains and 3-13 % for Far Eastern-subtype strains.Journal of General Virology 11/2010; 91(Pt 11):2706-12. · 3.36 Impact Factor -
Article: Collagen synthesis and mineralization in the early phase of distraction bone healing.
[show abstract] [hide abstract]
ABSTRACT: Corticotomy of the distal radius followed by gradual distraction by external fixation was performed on three sheep. Collagen synthesis and mineral deposition were analysed from sequential biopsies obtained from the center of the distraction area during the first 4 weeks of distraction. The whole distraction area was rapidly filled with organic matrix the amount of which, due to fluctuation in its nonprotein component, initially decreased from 88 to 66% of the level in control bone but gained its initial level in 4 weeks. Total protein in the matrix represented 70% of that in the control bone during the 4-week follow up period while the proportion of collagen of the total protein increased from 53 to 88%, a level comparable with the unoperated bone. Determination of the type of fibrillar collagen by characterization of their cyanogen bromide peptides showed that in the distraction area production of type II collagen does not occur but the heteropolymer type I (alpha 1(I)2 alpha 2(I)1) collagen represents almost totally the collagen synthesized. Deposition of mineral into the distraction gap was detectable already after 2 weeks and increased rapidly after 3 weeks of distraction. The results suggest that unlike in other processes, e.g., direct osteonal and callus-type bone repair, in distraction bone healing gradual distraction of osteotomized bone leads directly to synthesis of mature fibrous organic matrix of bone followed by its rapid mineralization.Bone and Mineral 10/1990; 10(3):171-81.
