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  • Article: Multiple scattering and intensity fluctuations in optical coherent tomography of randomly inhomogeneous media
    V. L. Kuzmin, I. V. Meglinski
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    ABSTRACT: An expression for signal intensity fluctuations in optical coherent tomography has been obtained for the first time in the framework of the theory of the multiple scattering of low-coherent optical radiation in a random medium. The contribution of the multiple scattering of low-coherent radiation backscattered from a randomly inhomogeneous layer, as well as the speckles of the interference component in optical coherent tomography, has been calculated.
    Journal of Experimental and Theoretical Physics 04/2012; 105(2):285-291. · 1.03 Impact Factor
  • Article: Dependence of the circular polarization of backscattered light in random media on anisotropy of scatterers
    V. L. Kuzmin, I. V. Meglinski
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    ABSTRACT: The scattering of linearly or circularly polarized light from a semi-infinite randomly inhomogeneous medium is considered. Using the Monte Carlo method, it is shown that, in the case of a wide front of incident and scattered optical radiation and irrespective of the degree of scattering anisotropy, the copolarized component of backscattered light dominates the cross-polarized component for the linear polarization and the cross-polarized component dominates the copolarized component for the circular polarization. If the beams of incident and scattered radiation are spatially separated and the size of scatterers exceeds the wavelength, the circular copolarized component dominates the cross-polarized one. A similar effect of the change in direction of the rotation of the plane of polarization in relation to the size of scatterers is revealed for pulsed radiation.
    Optics and Spectroscopy 04/2012; 108(1):99-106. · 0.61 Impact Factor
  • Article: Imaging of subcutaneous blood vessels and flow velocity profiles by optical coherence tomography
    M. Bonesi, S. G. Proskurin, I. V. Meglinski
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    ABSTRACT: We have applied a compact low power rapid scanning Doppler Optical Coherence Tomography system to monitor multi-dimensional velocity profiles within the complex vessels and simultaneous real-time non-invasive imaging of skin tissues morphology in vivo, in the wavelength range of 1.3–1.5 nm. Optical clearing of skin tissues has been utilized to achieve depth of OCT images up to 1.7 mm. Current approach enables applying low-power (0.4–0.5 mW) and low-noise broadband near-infrared light sources and obtaining OCT images with down to 12 μm spatial resolution. Two-dimensional time-domain OCT images of complex flow velocity profiles in blood vessel phantom and in vivo subcutaneous human skin tissues are presented. The effect of optical clearing on in vivo images is demonstrated and discussed.
    Laser Physics 04/2012; 20(4):891-899. · 3.61 Impact Factor
  • Article: Multimodal imaging of vascular network and blood microcirculation by optical diagnostic techniques
    Y. L. Kuznetsov, V. V. Kalchenko, I. V. Meglinski
    Quantum Electronics. 01/2011; 41:308.
  • Article: Monitoring of blood proteins glycation by refractive index and spectral measurements
    O.S. Zhernovaya, V.V. Tuchin, I.V. Meglinski
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    ABSTRACT: Monitoring of blood glucose and glycated proteins level is an urgent requirement for diabetic patients. The amount of glycated hemoglobin and glycated albumin depends on blood glucose concentration and reflects the mean glycemia. The purpose of this study is to investigate the effect of presence of glucose and glycation of proteins on optical properties of water solutions of hemoglobin and albumin with different glucose concentrations. We present the results of feasibility study of the refractive index measurements for water solutions of hemoglobin and albumin with glucose by Abbe refractometer. In addition, absorbance spectrum of water solutions of hemoglobin and albumin with different glucose concentrations has been studied. The experimental results show that the changes of optical properties caused by glycation of proteins can be observed by refractive index and spectral measurements. The refractive index measurements can be potentially applied for evaluation of glycated hemoglobin and glycated albumin amount in blood. (© 2008 by Astro Ltd., Published exclusively by WILEY-VCH Verlag GmbH & Co. KGaA)
    Laser Physics Letters 02/2008; 5(6):460 - 464. · 9.97 Impact Factor

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