Haleh Aghajani

Publications (4) View all

• Article: Discrimination of bilateral finger photoplethysmogram responses to reactive hyperemia in diabetic and healthy subjects using a differential vascular model framework.

  Adib Keikhosravi, Haleh Aghajani, Edmond Zahedi
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  ABSTRACT: Endothelial dysfunction assessment has received considerable attention due to its potential in early screening of cardiovascular diseases. Since the seminal work by Celermajer in flow-mediated dilation (FMD) based on B-mode ultrasound measurement of the brachial artery dilation following limb ischemia, many attempts have been made toward applying this method to clinical, non-invasive endothelial dysfunction assessment. One major obstacle toward achieving this objective has been the relative high cost of the required setup and skilled manpower. Such limitations have prompted the investigation of other non-invasively accessible signals such as the photoplethysmogram (PPG) in relation to FMD. It is in the above context that this paper proposes to use a modified version of an existing differential model of the human upper vasculature in order to discriminate between healthy and diabetic subjects. PPG from 46 subjects (23 healthy and 23 diabetic) were utilized to identify the model parameters. Once the model parameters were identified, singular value decomposition was applied to reduce the number of features and increase the separability. Finally, a naive Bayes classifier resulted in an overall accuracy of 93.5% (Spec. 87.0% and Sens. 100%). Taking into account subjects' gender further improved the overall accuracy. It is thought that the application of the proposed method to endothelial dysfunction assessment may positively impact the deployment of FMD in clinical settings.
  Physiological Measurement 04/2013; 34(5):513-525. · 1.68 Impact Factor
• Article: Diagnosis of Early Alzheimer's Disease based on EEG Source Localization and a Standardized Realistic Head Model

  Haleh Aghajani, Edmond Zahedi, Mahdi Jalili, Adib Keikhosravi, Bijan Vosoughi Vahdat
  IEEE Journal of Biomedical and Health Informatics. 03/2013;
• Article: Experimental Investigation of the Roles of Blood Volume and Density in Finger Photoplethysmography

  Adib Keikhosravi, Edmond Zahedi, Hamid Movahedian Attar, Haleh Aghajani
  IEEE Sensors Journal 01/2013; · 1.52 Impact Factor
• Article: A comparative study on distributed sources of cortical rhythms for diagnosis of Alzheimer's disease based on EEG: Using sLORETA

  Haleh Aghajani, Bijan Vosoughi-Vahdat, Mahdi Jalili
  04/2012;