Gunjan Maheshwari
Doctrate in Chemistry
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Topics (8)

Skills (5)

Research experience

  • Aug 2007–
    Oct 2012
    Research: Spectrophotometric and thin layer chromatographic analysis of antibiotics
    Harcourt Butler Technological Institute · Chemistry
    India · Nawabganj
    I have four years research experience from Analytical Research laboratory, H.B.T.I., Kanpur
  • Aug 2007–
    Oct 2012
    Research: Harcourt Butler Technological Institute
    Harcourt Butler Technological Institute
    India · Nawābganj

Education

  • Aug 2007–
    Oct 2012
    Harcourt Butler Technological Institute, Kanpur
    Analytical chemistry · Ph.D. (Chemistry)
    India · Kanpur

Awards & achievements

  • Mar 2008
    Award: Director's Medal in M.Sc. chemistry

Other

  • Languages
    Hindi and English

Questions and Answers (10) View all

Publications (3) View all

  • Article: Chromatographic separation studies of penicillins, cephalosporins and carbapenems on transition-metal silicate modified silica layers.
    Dhruv K Singh, Gunjan Maheshwari
    [show abstract] [hide abstract]
    ABSTRACT: The chromatographic behavior of penicillins, cephalosporins and carbapenems has been studied on the thin layers of transition-metal ion (viz. Ni(2+)/Zn(2+)/Cu(2+)/Co(2+)) silicate modified silica. Transition-metal silicate (3.92%) and silica (96.08%) were found to be optimum and resulted in spherical-compact spots and improved resolution of the analytes. The effect of various mobile phases was also investigated. The chromatograms were visualized as yellow spots by placing in an I(2)-chamber. The method has been found to be reproducible and convenient for routine analysis.
    Analytical Sciences 01/2012; 28(8):823-6. · 1.25 Impact Factor
  • Article: Chromatographic studies of some cephalosporins on thin layers of silica gel G-zinc ferrocyanide.
    Dhruv K Singh, Gunjan Maheshwari
    [show abstract] [hide abstract]
    ABSTRACT: A simple, selective and precise thin-layer chromatographic method has been developed for the analysis of eight cephalosporin antibiotics, namely cephadroxil, cephalexin, cefixime, cefaclor, cefpodoxime proxetil, cefuroxime axetil, cefotaxime sodium and ceftriaxone sodium. The hR(F) values of these cephalosporins were investigated on silica gel G-zinc ferrocyanide layers. Mixing of zinc ferrocyanide with silica gel G resulted in a decrease in hR(F) values, removal of tailing and better resolutions. The influence of silica gel G-zinc ferrocyanide ratio and mobile phases on the chromatographic behavior of cephalosporins on thin layers was investigated. Cephalosporins were selectively separated in their binary and ternary synthetic mixtures and pharmaceutical formulations. Quantitative separations of cephalosporins from their synthetic mixtures were also achieved with good recoveries (97.8-100.3%).
    Biomedical Chromatography 10/2010; 24(10):1084-8. · 1.97 Impact Factor
  • Article: Spectrophotometric determination of penicillins in pure and pharmaceutical formulations using Folin-Ciocalteu reagent.
    Dhruv K Singh, Gunjan Maheshwari
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    ABSTRACT: A new combination of time, temperature, and alkali is described for the spectrophotometric determination of amoxicillin and ampicillin using Folin-Ciocalteu reagent. The method is based on the development of blue-coloured product due to the reduction of tungstate and/or molybdate in Folin-Ciocalteu reagent by amoxicillin and ampicillin in alkaline medium. The chromogenic reaction has λ(max) at 720 and 740 nm with molar absorptivity 1.6295 × 10⁴ and 0.1085 × 10⁴ l mol⁻¹ cm⁻¹ in the Beer's Law range 2-10 µg mL⁻¹ and 10-70 µg mL⁻¹ for amoxicillin and ampicillin, respectively. The method is reproducible, quick, inexpensive, and particularly helpful in determining the drug content in commercial dosage forms.
    Drug Testing and Analysis 10/2010; 2(10):503-6. · 2.54 Impact Factor

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