Article: Effect of VX-770 (Ivacaftor) and OAG on Ca(2+) influx and CFTR activity in G551D and F508del-CFTR expressing cells.3Views0Downloads0Citations
Article: C-Branched Iminosugars: alpha-Glucosidase Inhibition by Enantiomers of isoDMDP, isoDGDP and isoDAB - L-isoDMDP Compared to Miglitol and Miglustat.6Views0Downloads0Citations
Article: Missense Mutations in SLC26A8, Encoding a Sperm-Specific Activator of CFTR, Are Associated with Human Asthenozoospermia.11Views1Download0Citations
I am interested in the pharmacology and function of chloride channels and especially of the epithelial cAMP-regulated and ATP-gated CFTR and its role in the human genetic disease cystic fibrosis. With my research group, we are screening small molecules with the aim to identify new therapeutics for CF patients.