Fernando Pardo

Publications (153) View all

• Source

  Available from: Fernando Pardo

  Dataset: A Prospective, Multicenter Study of Once-Daily

  R Charco, M Caralt, L Lladó, A Valdivieso, J Fabregat, A Matarranz, I Gonzalez-Pinto, F Pardo, E Fábrega, I Bilbao
• Article: Efficacy of transjugular intrahepatic portosystemic shunt to prevent total portal vein thrombosis in cirrhotic patients awaiting for liver transplantation.

  D D'Avola, J I Bilbao, G Zozaya, F Pardo, F Rotellar, M Iñarrairaegui, J Quiroga, B Sangro, J I Herrero
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  ABSTRACT: Complete portal vein thrombosis (PVT) may complicate orthotopic liver transplantation (OLT), increasing its technical difficulty and the transfusion requirements and as well as affecting survival in some cases. Transjugular intrahepatic portosystemic shunt (TIPS) prevents total portal vein occlusion in patients with partial PVT. We aimed to assess the efficacy and safety of TIPS to prevent total portal vein occlusion among patients listed for OLT. We analyzed the clinical records of 15 consecutive patients with partial PVT who underwent TIPS before OLT. The control group consisted of 8 transplanted patients without TIPS but partial PVT diagnosed before OLT. Portal vein patency at surgery, ischemia time, and transfusion requirements during OLT, and survival thereafter were compared between both groups. The main complications were also compared: mortality after TIPS (from TIPS placement to OLT), intraoperative technical complications, and technical complications during the 6 months after OLT. Clinical characteristics at the time of OLT were similar between the groups. No relevant complications were observed after TIPS; all patients underwent transplantation. One- and 5-year actuarial survival rates were similar in both groups (92% and 85% in TIPS-group versus 100 and 75% in the control group, respectively). No differences in transfusion requirement, duration of ischemia, and frequency of technical complications during and after OLT were observed between the groups. The portal vein was patent at surgery in all TIPS patients and 4 of 8 (50%) in the control group (P = .008). TIPS may prevent PVT in liver transplantation candidates with partial PVT.
  Transplantation Proceedings 11/2012; 44(9):2603-5. · 1.00 Impact Factor
• Article: Efficacy of laparoscopic approach in the management of early liver transplant complications.

  N Pedano, F Rotellar, J Alvarez-Cienfuegos, J Arredondo, M Bellver, P Martínez, C Sánchez, P Martí, G Zozaya, J I Herrero, F Pardo
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  ABSTRACT: The use of the laparoscopic approach in managing early liver transplant complications has been shown to be safe and feasible in various settings with the advantages of shorter recovery period, decreased postoperative pain, and rapid functional recovery. The laparoscopic approach has been used to resolve postoperative complications in kidney and pancreas recipients and less often in orthotopic liver transplantation (OLT) recipients, most of them in the late period (> 1 month posttransplantation). We herein describe our experience with the laparoscopic management of early complications after liver transplantation. From May 2009 to May 2011, we successfully treated three patients with early abdominal complications after OLT using a laparoscopic approach. Three patients-two with intraabdominal bleedings and one with a small bowel obstruction were treated successfully, thereby avoiding risks of a relaparotomy. In addition to these benefits, the laparoscopic approach causes less tissue injury and consequently evokes a minor innate immune response.
  Transplantation Proceedings 07/2012; 44(6):1560-1. · 1.00 Impact Factor
• Article: Subsequent nonmelanoma skin cancer after liver transplantation.

  J I Herrero, A España, D D'Avola, F Pardo, M Iñarrairaegui, F Rotellar, B Sangro, J Quiroga
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  ABSTRACT: Liver transplant recipients have a high risk of developing nonmelanoma skin cancer (NMSC). Some develop multiple NMSC. Patients with a follow-up of >1 year have been prospectively followed to detect NMSC. We studied the risk of developing >1 NMSC. After a follow-up of 2658 patient-years (mean, 8.5 years per patient), 59/312 (19%) patients were diagnosed with NMSC. Twenty-five had >1 NMSC. The 5-year risk of developing 1 NMSC, >1 NMSC, and a subsequent NMSC (a new NMSC after a first one) were 15%, 5.5%, and 46.5%, respectively. Age >60 years and transplantation for hepatocellular carcinoma were independently associated with a higher risk of developing >1 NMSC. NMSC are frequent complications after liver transplantation and they may show a high rate of recurrence. Older age and hepatocellular carcinoma were related to the development of multiple NMSC.
  Transplantation Proceedings 07/2012; 44(6):1568-70. · 1.00 Impact Factor
• Article: Ascites due to anastomotic stenosis after liver transplantation using the piggyback technique: treatment with endovascular prosthesis.

  J I Bilbao, J I Herrero, A Martínez-Cuesta, J Quiroga, J C Pueyo, I Vivas, C Delgado, F Pardo
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  ABSTRACT: Liver transplantation preserving the retrohepatic inferior vena cava, the so-called piggyback technique, is becoming more frequently used because it avoids caval cross-clamping during the anhepatic phase of surgery. However, hepatic venous outflow blockade causing ascites seems to be less infrequent after piggyback than with cavo-caval anastomosis. We report a 62-year-old patient who underwent liver transplantation using the piggyback technique and developed a stenosis in the anastomosis between the hepatic veins and the inferior vena cava leading to severe postoperative ascites. Ascites was unresponsive to diuretic therapy and was associated with renal function impairment. Since the etiology of the stenosis was mechanical (torsion), percutaneous transluminal angioplasty was unsuccessful. Finally, an autoexpandable prosthesis was placed across the anastomosis resulting in rapid and permanent (3 years of follow-up) resolution of ascites.
  CardioVascular and Interventional Radiology 04/2012; 23(2):149-51. · 2.09 Impact Factor