Federico Gonzalez Grassi

Cell Biology, Genetics, Cancer Research



Awards and achievements (4) View all

  • Jan 2015
    Best of Cell Stem Cell 2014 selection: An iCRISPR Platform for Rapid, Multiplexable, and Inducible Genome Editing in Human Pluripotent Stem Cells.
  • Nov 2011
    New York State Stem Cell (NYSTEM) Science Fellow - Center for Stem Cell Biology of the Sloan-Kettering Institute
  • Jul 2008
    Postdoc Fellowship For Advanced Researchers - Swiss National Science Foundation (SNSF)


Advances in next-generation sequencing and genome-wide association studies have led to the rapid discovery of a vast amount of disease-associated mutations. In order to efficiently elucidate their function, we recently developed an iCRISPR platform for efficient and inducible gene editing in human pluripotent stem cells (hPSCs). We are currently combining iCRISPR and tissue engineering in hPSCs to generate 3D organoid models to study different aspects of human development and disease in vitro.

Skills and expertise(26) View all