Skills (17)
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32 Questions2223 Followers
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495 Questions74715 Followers
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975 Questions118113 Followers
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0 Questions2 Followers
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22 Questions33 Followers
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1 Question2 Followers
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2 Questions39 Followers
Research experience
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Dec 2010–
presentResearch: Development of diagnostic and research tool based on the innate immunity
Rheinische Friedrich-Wilhelms-Universität Bonn · Faculty of Medicine · Institute of Innate ImmunityGermany · Bonn -
Mar 2009–
Oct 2009Research: Role of Mda5 (IFIH1) in the development of type 1 diabetes.
Monash University · Monash Institute of Medical Research · Monash UniversityCancer Research, Cancer and Innate Immunity · Melbournemetabolism, innate immunity, Mda5 -
Feb 2008–
Jun 2008Research: Role of CXCL5 in the development of type 2 diabetes
University Montpellier II · Institut de recherche en cancérologie de Montpellier · University Montpellier IIMetabolism and Cancer · Montpelliermetabolism, chemokine, CXCL5
Education
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Dec 2009
University Clinic Bonn
Innate Immunity, Biotechnology, Protein engineering · Dr. Rer. Nat.Germany · Bonn -
Mar 2009
Monash Institute of Medical Research
Master InternshipAustralia · Melbourne -
Mar 2008
Institut de Recherche en Cancérologie de Montpellier
Master (1st year) InternshipFrance · Montpellier -
Sep 2007–
Oct 2009Montpellier II
Health Biology - Biotechnology · Master of ScienceFrance · Montpellier -
Sep 2004–
Jun 2007UAPV
Biology · Bachelor of ScienceFrance · Avignon
Other
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LanguagesFrench (mother language), English (fluent written and spoken), German (advanced basis - B2)
Publications (1) View all
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Article: Innate immune receptors for nucleic acids.
Andrea Stutz, Damien Bertheloot, Eicke Latz[show abstract] [hide abstract]
ABSTRACT: The innate immune system has evolved to detect microbes and sterile tissue damage with the help of a series of signaling receptors. One key strategy is to detect infectious microbes or host cell damage by recognizing nucleic acids that are modified or appear in compartment normally devoid of nucleic acids. Here, we describe two methods that allow studying the molecular interaction between various nucleic acid recognizing signaling receptors with their ligands. A ligand pull-down assay can be used to show a known interaction between a ligand and its receptor or the method can be utilized as a discovery approach to identify an unknown receptor to a given ligand. An AlphaScreen experiment can be set up to assess the ligand binding affinity to a given receptor.Methods in molecular biology (Clifton, N.J.) 01/2011; 748:69-82.