Etablished an international reputation in clinical/research aspects of cancer genetics, particularly neurofibromatosis and breast cancer. Published 538 peer reviewed research publications; 203 as first /senior author, with over 250 on breast cancer. Chairman/Clinical Lead of NICE Familial Breast Cancer GDG (2002-13 In last 5 years raised over £10 million in grants for multicentre/local studies – £4 million to Manchester including PI of £1.59 million NIHR programme grant.

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