Chinnathambi Velu

M.Sc.,(Biotechnology & Bioinformatics)
ARMATS BIOTEK Training and Research institute · Department of Applied environmental biotechnology

Research skills

  • Technical
    Fermentation, DNA Isolation, protein purification (ion exchange & affinity columns, Reactor Design, Enzyme immobilization., Protein Isolation, Protein Characterization, SDS-PAGE
  • IT
    Windows, C, C++, Bioperl, python(beginner
  • Statistical
    Design Expert software (DOE, Minitab) Optimization design such as Placket Burnmann, Response surface methodology(RSM
  • Other
    Sequence Analysis, Phylogenetic Analysis, Drug Designing and Molecular Modelling, Homology Modeling

Research interests

  • Interests
    Genetic Engineering, Microbial enzyme technology, Bio-remediation & Bio-degradation

Other

  • Languages
    Tamil, English

Publications

  • COMPARATIVE EVALUATION OF WHITE WINE PRODUCTION FROM DIFFERENT CARBOHYDRATE RICH SUBSTRATES USING AIR-LIFT BIO-REACTOR

    Chinnathambi V, Karthik Raja G, Yazhini K.A, Sridhar S, Ezhilarasan V

    International Journal of pharma and Bio sciences. 01/2012; 3(1-B-45):392-404.

    In recent years, wine consumption rate has increased in India. Grapes are used as a primary source in wine production, all over the world. A number of studies have been conducted on apple, guava, banana, jamun, strawberry, apricot, kinnow and plum in order to find an alternate resource. The major ob... [more] In recent years, wine consumption rate has increased in India. Grapes are used as a primary source in wine production, all over the world. A number of studies have been conducted on apple, guava, banana, jamun, strawberry, apricot, kinnow and plum in order to find an alternate resource. The major objectives of this study are the production of wine using sweet potato and also to find an effective combinational resource. Initially, white wine was produced using sweet potato. Through a detailed analysis, it was confirmed that the rate of white wine production was higher in sweet potato when compare to grapes and figs. Finally, different combinational white wine productions were performed with the help of air-lift bio-reactors. Results suggest that a combination of sweet potato with grapes and sweet potato with beetroot and banana was effective. Anti-microbial activity was carried out in order to verify the fidelity of the produced wine.
  • Insilico Screening and Comparative Study on the Effectiveness of Textile Dye Decolourization by Crude Laccase Immobilised Alginate Encapsulated Beads from Pleurotus Ostreatus

    Chinnathambi Velu, Ezhilarasan Veeramani, Sridhar Suntharam, Kasinathan Kalimuthu

    Journal of Bioprocessing & Biotechniques. 01/2011; 1:109.

    The necessity to safeguard the environment has increased the potential of enzyme usage in textile processing to ensure eco-friendly production. Laccase enzyme formulation has been used in textile processing such as biobleaching, dyeing, rove scouring, finishing, neps removal, printing, wash-off trea... [more] The necessity to safeguard the environment has increased the potential of enzyme usage in textile processing to ensure eco-friendly production. Laccase enzyme formulation has been used in textile processing such as biobleaching, dyeing, rove scouring, finishing, neps removal, printing, wash-off treatment, dye synthesis and effluent treatment. However, a high cost associated with biocatalyst production is still a hindrance to their use. Pleurotus ostreatus is a white-rot fungus that produces a ligninolytic enzyme complex rich in several laccase iso-enzymes. The main objective of this study is optimize influence of pH and stability of divalent metal ion-immobilzed crude laccase enzyme towards decolourization of prototype textile dyes such as Reactive red 80 (Red F3B) and Reactive blue 21(T Blue G). Wheat bran is used as a lead candidature for production of lignolytic enzyme using Pleurotus osteratus by solid state fermentation. Two divalent metal ions such as Zn2+ and Ca2+ were selected to study the influence of metal ions towards the dye decolourization. Results revealed that Ca2+ ion was better compared to Zn2+ ion towards enzyme immobilization and its influence on dye decolourization in the optimal pH 5.5. Finally, interactions between laccase and dyes were studied exclusively using Insilco structure based molecular docking methods.
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