C. Suresh Reddy

Publications (63) View all

• Source

  Available from: C.Bhupendra Reddy

  Article: PEG-SO(3)H catalyzed synthesis and cytotoxicity of α-aminophosphonates.

  C Bhupendra Reddy, K Suresh Kumar, M Anil Kumar, M Veera Narayana Reddy, B Satheesh Krishna, M Naveen, M K Arunasree, C Suresh Reddy, C Naga Raju, C Devendranath Reddy
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  ABSTRACT: One pot three-component PEG-SO(3)H catalyzed reaction of 4-(Pyridin-4-yl)benzaldehyde and triethyl phosphite with various primary amines afforded α-aminophosphonates with high yields by the Kabachnik-Field's reaction. These new structurally diversified set of α-aminophosphonates (4a-j) were evaluated for their anti-tumor activity on human chronic myeloid leukemia cells (K 562), human colon carcinoma cells (Colo 205) along with non-cancerous human embryonic kidney cells (HEK 293). They showed moderate activity on both cancerous cells and non-cancerous cells.
  European journal of medicinal chemistry 11/2011; 47(1):553-9. · 3.27 Impact Factor
• Article: Synthesis, Antimicrobial, and Antioxidant Activity of New α-Aminophosphonates

  S. Subba Reddy, V. Koteswara Rao, B. Satheesh Krishna, C. Suresh Reddy, P. Visweswara Rao, C. Naga Raju
  Phosphorus Sulfur and Silicon and the Related Elements 07/2011; Sulfur(and Silicon and the Related Elements):1411-1421. · 0.72 Impact Factor
• Article: Synthesis and bio-activity evaluation of tetraphenyl(phenylamino) methylene bisphosphonates as antioxidant agents and as potent inhibitors of osteoclasts in vitro.

  A Balakrishna, M Veera Narayana Reddy, P Visweswara Rao, M Anil Kumar, B Siva Kumar, S K Nayak, C Suresh Reddy
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  ABSTRACT: A new series of tetraphenyl bisphosphonates have been elegantly synthesized by one-pot method and were characterized by elemental analysis, FTIR, 1H, 13C, 31P NMR, mass spectra and evaluated for their in vitro antibone resorptive activity by inhibiting growth of osteoclasts. Two bisphosphonates 3g and 3f showed marked inhibition ratio (8 μM and 10 μM) and emerged as lead compounds. All compounds were tested for their antioxidant (DPPH scavenging, reducing power and inhibition of lipid peroxidation). They exhibited potent in vitro antioxidant activity dose-dependently.
  European journal of medicinal chemistry 02/2011; 46(5):1798-802. · 3.27 Impact Factor
• Article: Synthesis, spectral characterization and bioassay of 3,3'-(1,4-phenylene)-bis[2-alkoxycarbonyl-alkyl)-2-thio-benzoxa-phosphinines].

  M Veera Narayana Reddy, A Bala krishna, C Suresh Reddy
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  ABSTRACT: Synthesis of 3,3'-(1,4-phenylene)-bis[2-alkoxycarbonyl-alkyl)-2-thio-benzoxaphos-phinines] (3a-j) were accomplished via two step process. It involves the prior preparation of monochloride intermediate (2) and its subsequent reaction with the amino acid esters in dry tetrahydrofuran-toluene in the presence of triethylamine at reflux temperature. These compounds were characterized by IR, 1H, 13C, 31P NMR and were found to exhibit potent in vitro antioxidant activity.
  European journal of medicinal chemistry 05/2010; 45(5):1828-32. · 3.27 Impact Factor
• Article: Synthesis, Spectral characterization and antimicrobial activity of 2-(substituted)-2,2-[1,3- dihydro-(3,4-1,2,5-oxadiazolediyl) diaza][5 ׳ , 5 ׳ -dimethyl-1 ׳ , 3 ׳ -propanediyl) dioxy] phosphoranes

  Y. Hari Babu, A. Uma Ravi Sankar, B. Siva Kumar, C. Suresh Reddy
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  ABSTRACT: The cyclic oxadiazolediyl dioxachlorophosphine precursor on subsequent reaction with various alcohols underwent halide displacement to give 2-substituted diaza phospholes. These phospholes on oxidative addition with di hydroxy alcohols form corresponding phosphoranes The antimicrobial activities of these compounds were evaluated and they exhibited significant antimicrobial activity.
  Organic Communications. 01/2010;