Publications (33) View all
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Article: Calcium intake and osteoporosis: the influence of calcium intake from dairy products on hip bone mineral density and fracture incidence - a population-based study in women over 55 years of age.
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ABSTRACT: OBJECTIVE: The incidence of osteoporosis increases with age and is most frequently observed in postmenopausal women. The objective of the present population-based cohort study was to assess the influence of Ca intake from dairy sources on hip bone mineral density and hip fracture incidence in a group of Polish women over 55 years of age. DESIGN: The main outcome measures included: bone mineral density, the number of previous fractures and the reported Ca intake from dairy sources, assessed by a diet questionnaire. SETTING: The RAC-OST-POL Study was conducted in the District of Raciborz in the south of Poland. SUBJECTS: The study was carried out in a group of 625 women, randomly recruited from the general population of women aged >55 years. RESULTS: Median Ca intake from dairy products was lower in the group of women with femoral neck T-score ≤-2·5 than in the group with T-score >-2·5 (275 v. 383 mg/d; P = 0·0019). For total hip score, the difference was close to borderline significance (P = 0·0698). Median Ca intake from dairy products was lower in the group of women with previous fractures than in those without fracture history (336 v. 395 mg/d; P = 0·0254). The main dairy source of Ca in the analysed group included milk drinks, rennet cheese and milk. CONCLUSIONS: Higher dairy Ca intake is recommended, since a number of the women analysed were unable to satisfy their Ca requirement exclusively from their diet.Public Health Nutrition 12/2012; · 2.17 Impact Factor -
Article: Adiponectin and resistin in relationship with skeletal status in women from the RAC-OST-POL study.
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ABSTRACT: Introduction: The aim of this study was to establish adiponectin and resistin serum levels and their relationship with skeletal status in women from the RAC-OST-POL study. Material and methods: 40 women with the lowest and 40 women with the highest value of bone mineral density (BMD) measured at the femoral neck (FN) were selected from a total of 625 women after dividing them into six age categories. Mean age in the whole group of 80 women was 66.1 ± 8.0 years. 22 women had osteoporotic fractures. Adiponectin and resistin were measured, and skeletal assessment included measurements of BMD of FN and total hip (TH) using Lunar DPX (USA) and quantitative ultrasound (QUS) of hand phalanges by means of DBM Sonic 1200 (IGEA, Italy). Results: Mean age did not differ between the subgroups, whereas height, weight, BMI and BMD were significantly higher in women with high BMD values. In women with high and low BMD, adiponectin concentration [μg/mL] was 24.81 ± 12.7 and 31.04 ± 12.64 respectively, and differed significantly (p 〈 0.05). Respective values for resistin concentration [ng/mL] were 3.29 ± 1.37 and 3.62 ± 1.45, and did not differ. Adiponectin negatively correlated with weight (r = -0.34, p 〈 0.01), BMI (r = -0.37, p 〈 0.01), FN BMD (r = -0.26, p 〈 0.05), TH BMD (r = -0.33, p 〈 0.01), and did not correlate with QUS result. Stepwise multiple regression analysis showed that TH BMD was negatively influenced by age and adiponectin and positively by weight, and that FN BMD was dependent on age and weight only. Conclusions: Our results suggest that adiponectin may be an independent factor influencing skeletal status in women aged over 55 years. (Endokrynol Pol 2012; 63 (6): 427-431).Endokrynologia Polska 01/2012; 63(6):427-31. · 1.24 Impact Factor -
Article: Assessment of skeletal status by quantitative ultrasound at the hand phalanges in children with bronchial asthma--a pilot study.
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ABSTRACT: The aim of the study was to assess the skeletal status by quantitative ultrasound measurement at hand phalanges in asthmatic children treated with inhaled corticosteroids. Sixty-nine (69) children with a mean age of 10.9 ± 2.6 y and 251 controls matched for age and body size were enrolled into the study. The mean value of amplitude-dependent speed of sound in asthmatic children was 1953.8 ± 60.2 m/s and the mean Z-score was -0.05 ± 1.02; the corresponding values in the controls were 1951.0 ± 53.9 m/s and -0.26 ± 1.05, respectively. The results did not differ between the asthmatic and the healthy (control) children. A cumulative dose of inhaled steroids was identified in a stepwise regression analysis as a factor with potentially negative influence on bone status. In conclusion, the skeletal status in asthmatic children, assessed by quantitative ultrasound, shows no difference in comparison with healthy children. Nonetheless, special caution is necessary in case of long-term corticosteroid therapy, in which a slightly negative influence of treatment on the skeleton cannot be excluded.Ultrasound in medicine & biology 09/2011; 37(11):1802-7. · 2.02 Impact Factor -
Article: Fracture status in men assessed by quantitative ultrasound measurements at the calcaneus.
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ABSTRACT: The aim of the study was to assess fracture status in men by quantitative ultrasound measurements at the calcaneus. The diagnostic accuracy of quantitative ultrasound measurements was evaluated at baseline and follow-up. We observed 165 men (baseline age ± SD, 59.84 ± 10.6 years) recruited from an outpatient osteoporosis clinic. The mean follow-up duration was approximately 101.3 ± 35 months. There was no difference in either age or body mass index at baseline between the patients with a fracture history (n = 30) and the others (n = 135). The following fractures were identified at baseline: ankle, 15; wrist, 10; rib, 9; foot, 5; and hip, 1. The speed of sound (meters per second), broadband ultrasound attenuation (decibels per megahertz), and stiffness index (percent) were measured with a quantitative ultrasound device. The date of fracture occurrence at follow-up was defined as the final point. In the patients with a fracture history, the ultrasound variables were significantly lower than those in the rest of the group (P < .05). During the follow-up period, fractures occurred in 21 patients (wrist, 11; ankle, 5; rib, 3; hip, 1; and humerus, 1), and the ultrasound outcomes were nonsignificantly lower in the fractured men. The risk of fracture was estimated by the Cox regression analysis. A prior fracture was the only factor that significantly (4 times) increased the risk of a subsequent fracture (hazard ratio, 4.21; 95% confidence interval, 1.81-9.86; P < .001). Calcaneus ultrasound measurements can distinguish between patients with fractures and those without. In follow-up, ultrasound measurements did not indicate an increased fracture risk; a prior osteoporotic fracture was the major prognostic factor.Journal of ultrasound in medicine: official journal of the American Institute of Ultrasound in Medicine 07/2011; 30(7):877-82. · 1.25 Impact Factor -
Article: Skeletal status assessed by quantitative ultrasound at the hand phalanges in karate training males.
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ABSTRACT: The aim of the study was to assess the influence of regularly exercised karate on the skeletal status. The study comprised a group of 226 males (the mean age: 25.64 ± 12.3 years, range 7-61 years), exercising for 61.9 ± 68.4 months, with the mean frequency of 3.12 ± 1.4 times per week, and 502 controls, matched for age and body size. The skeletal status was assessed by quantitative ultrasound, using a DBM Sonic 1200 (IGEA, Italy) sonographic device, which measures amplitude-dependent speed of sound (Ad-SoS [m/s]) at hand phalanges. Ad-SoS, T-score, Z-score were significantly higher in the examined karatekas than in controls. Up to age 18, there had been no difference between the study subjects and controls, while afterwards, up to age 35, the difference increased to stabilize again after age 35. Longer duration, higher frequency and earlier start of physical training positively influenced the skeletal status. In conclusion, karate is a sport with a positive influence on the skeletal status with the most significant benefits occurring in adults.Ultrasound in medicine & biology 02/2011; 37(2):214-9. · 2.02 Impact Factor
