Besiki Surguladze

Publications (9) View all

• Article: Novel method of sentinel lymph node detection in malignant tumors using preparation 'UNIMAG'

  B Surguladze, R Zhorzoliani, T Tskitishvili
  Breast Cancer Research 04/2012; 9:1-1. · 5.33 Impact Factor
• Article: [Effectiveness of unimag in the treatment of catarrhal gingivitis].

  N K Natsvlishvili, T G Tskitishvili, B V Surguladze, L Iu Kiparoidze, N Kh Khangoshvili
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  ABSTRACT: Results of microbiological investigation of catarrhal gingivitis on the background of treatment with Unimag are presented in the work. Preparation Unimag is a stable suspension of magnetic nano-particles. Unimag is magnetic-sensitive, X-ray contrast, bactericidal substance; it increases functional activity of phagocytes and characterizes with high penetration ability in tissues. Studies have revealed that treatment with Unimag of the patients with catarrhal and gingivitis rapidly normalizes quantity of microbes in the oral cavity, substituting the gram-negative pathogenic flora for the gram-positive microorganisms in the oral cavity. Unimag increases sensitivity of pathogenic flora towards the anti-bacterial preparations. All the above-mentioned are significant for efficient impact on damaging factors during inflammation.
  Georgian medical news 11/2009;
• Article: [Usage of unimag during dynamic hysterosalpingo-contrast sonography in the experimental study].

  R Sh Lutidze, B D Tkeshelashvili, B V Surguladze, D G Tatishvili, G V Mamukashvili
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  ABSTRACT: The purpose of this experimental study was to investigate the contrasting ability of magnetic fluid, Unimag, during dynamic hysterosalpingo-contrast sonography (HyCoSy) performed in sexually mature female rabbits. 5 ml of diluted and undiluted solution Unimag was slowly injected into the intact and amputated uterine tubes as experimental animals via a catheter. Dynamic observation was achieved with the aid of ultrasound machine - Siemens Sonoline Antares. Observation revealed a well - defined contrasting ability of this magnetic fluid regardless of its dilution. X-ray was additionally performed in above mentioned animals, also proved the contrasting ability of Unimag.
  Georgian medical news 06/2007;
• Article: [Dynamics of leukocytes' migration degree in oral cavity and parameters of INFgamma and TNFalpha in blood serum of patients suffering from parodontitis on the background of treatment with Unimag].

  M G Saralidze, L M Dzhashi, T G Tskitishvili, N N Gogebashvili, B V Surguladze
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  ABSTRACT: In the oral cavity of patients with parodontitis before treatment the quantity of migrated leukocytes (ML) was increased. Among them number of living cells was sharply reduced. In the process of treatment on the background of immune modulation with Unimag, the concentration of migrated leukocytes decreases and number of living leukocytes increases. The above-mentioned quantitative and qualitative parameters of migrated leukocytes were normalized after 1-1.5 months. The analogical dynamics has been detected in patients suffering from parodontitis and treated with traditional scheme. However, despite reduced concentration of migrated leukocytes and increased percentage of living leukocytes' content, normalization of the mentioned parameters has not been detected. In the blood serum of patients suffering from parodontitis increased concentration of INFgamma and TNFalpha have been revealed. In the process of treatment, concentration of the mentioned cytokines was decreased, however, in patients treated with Unimag on the background of immune modulation, decrease in concentration of INFgamma and TNFalpha was much more expressed.
  Georgian medical news 01/2006;
• Article: [Microbiological investigations and studies of phagocytic activities of peripheral neutrophils during the treatment of parodontitis by Unimag].

  M G Saralidze, L M Dzhashi, T G Tskitishvili, N N Gogebashvili, B V Surguladze
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  ABSTRACT: During the treatment by Unimag (UN), quantity of microbes in the mouth cavity of patients with periodontitis (PD), significantly decreases in comparison with the patients treated by traditional scheme. That is due to direct and indirect influence of UN on the pathogenic microorganisms. During the treatment of patients with PD by UN, quantity of Gram-negative microbes gradually decreases and their substitution by Gram-positive microbes, typical for mouth cavity, takes place. On the background of the treatment by UN, phagocytic activity (PA) of polynuclear cells (PC) increases. In comparison with the patients treated by traditional scheme, increases both phagocytic number and number of active neutrophils. On 14-15 days after beginning of treatment of patients with PD by traditional scheme, PA of PC does not change significantly. Reduction of the microbial number in the mouth cavity and the active substitution of Gram-negative microbes by Gram-positive microorganisms during the treatment of patients with PD by UN, have prognostic importance and together with the reinforcement of PA of PC indicate to the improvement of the therapeutic effect and shortening of the duration of the treatment.
  Georgian medical news 12/2005;