Publications (58) View all
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Article: Diffuse Cutaneous and Mucozal Erythema and Rash After Upper Respiratory Tract Infection
Öncel İbrahim, Çelik Melda, Kara AteşCocuk Enfeksiyon Dergisi. 01/2011; -
Article: Hepatitis A and B Discrimination According to Aminotransferases
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ABSTRACT: Objective: Acute infection of hepatitis A and B viruses is accompanied by biochemical evidence of liver injury. In acute symptomatic hepatitis, transaminase tests are markedly elevated, especially, in hepatitis A. This study was carried out to examine the feasibility of discrimination between hepatitis A and B in acute phase using serum transaminase concentrations so as to take isolation precautions and to plan supportive therapy in early phase. Methods: Between January 1996 and December 1998, 444 patients, [239 (53.8%) males and 205 (46.2%) females] are tested for hepatitis B surface antigen (HBsAg), hepatitis B core IgM antigen (anti-HBc IgM), and hepatitis A immunglobuline M (anti-HAV IgM), alanine aminotransferase (ALT), aspartat aminotransferase (AST) and bilirubin concentrations and comparison of transaminase concentrations between patients infected with hepatitis A and hepatitis B has been made.Results: ALT concentrations of HAV-infected patients had a median of 879 (minimum: 4, maximum: 7201), whereas HBV-infected patients had a median of 66 (minimum: 16, maximum: 3118). AST concentrations of HAV-infected patients had a median of 492 (minimum: 8, maximum: 5718), whereas HBV-infected patients had a median of 59,5 (minimum: 13, maximum: 2040). Transaminase concentrations of patients infected with hepatitis A are higher than patients infected with hepatitis B (for ALT and AST p<0,001). Also there was difference in transaminase concentration in acute hepatitis with age. Concentrations of serum transaminases in acute hepatitis increased with age and peaked at 7-8 years, having a median of 1565 (minimum: 9 and maximum: 4014) for AST and 1942 (minimum: 22 and maximum: 3950) for ALT.Conclusion: Discrimination between hepatitis A and B in acute phase using serum transaminase concentrations could be helpful to get isolation precautions and to plan supportive therapy in early phase.Cocuk Enfeksiyon Dergisi. 01/2011; -
SourceAvailable from: oxfordjournals.org
Article: Letter to the Editor
Çelik Melda, Kara AteşCocuk Enfeksiyon Dergisi. 01/2010; -
SourceAvailable from: Aslınur Özkaya Parlakay
Article: Winning the Battle Against Pseudomonas aeruginosa Endocarditis: A Case Report
Aslınur Özkaya Parlakay, Kara Ateş, Çelik İstemihan, Ali Bülent Cengiz, Karagöz Tevfik, Devrim İlker, Ceyhan Mehmet[show abstract] [hide abstract]
ABSTRACT: Infective endocarditis is a major risk for patients with congenital heart disease and has high mortality and morbidity rates, even though there have been many advances in antimicrobial therapy and surgical intervention techniques. Gram positive microorganisms, such as staphylococcus and streptococcus species, are the most commonly isolated organisms. Pseudomonas aeruginosa is a rare causative organism for infective endocarditis. It usually affects the right side of the heart, which is usually seen in intravenous drug users. Incidence of pseudomonas endocarditis has increased due to a higher frequency of drug abuse, heart surgery and bacteremia. Mortality from pseudomonas infective endocarditis remains high despite optimal use of available antibacterial agents and also the treatment plan is very challenging as there is no consensus to date. We report a patient with tetralogy of Fallot and recurrent P. aeruginosa endocarditis after corrective cardiac surgery. We wish to emphasize the importance of surgical intervention and also recall the significance of lenghtening the antipseudomonal combination therapy.Cocuk Enfeksiyon Dergisi. 01/2010; -
Article: Symptomatic Hepatitis A and Cholestatic Hepatitis as A Complication of Hepatitis A
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ABSTRACT: Hepatitis A infection is an acute, self limitting disease due to infection of the liver by hepatitis A virus , an enterically trasmitted virus which is a member of the Picornaviridae family. The infection may be asymptomatic or cause an acute hepatitis syndrome of varying degrees of severity up to and including fulminant hepatitis. While the duration of symptoms may vary widely, the disease does not lead to chronic hepatitis. In this study, the characteristics of cases admitting with acute hepatitis diagnosed as having hepatitis A infection and the follow-up of cholestatic hepatitis, which is the most common complication of hepatitis A infection, are investigated.Cocuk Enfeksiyon Dergisi. 01/2009;