Publications (157) View all
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Article: [Is atrial fibrillation an independent marker of cardiovascular risk?].
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ABSTRACT: Atrial fibrillation (AF) is the most frequent cardiac arrhythmia and its prevalence rises with age. AF may cause stroke and heart failure but the relationship between AF and mortality is less clear. It is difficult to determine if cardiovascular events in patients with AF are attributable to the arrhythmia itself or if they are merely related to the comorbidities frequently associated with AF. Review of the literature suggests that lone AF (without structural heart disease), a rare clinical entity except in young patients, is not an independent risk factor for mortality. On the other hand, if illnesses usually associated with AF are present (hypertension, heart failure...), AF has a negative impact on outcome in terms of survival and morbidity. Current antiarrhythmic medications have not shown reduction in mortality of AF patients, but new agents and catheter ablation are promising paths to explore in order to decrease AF burden.Annales de cardiologie et d'angeiologie 12/2010; 59 Suppl 1:S14-8. · 0.21 Impact Factor -
Article: [Pathophysiopathology of atrial fibrillation: applications to treatment].
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ABSTRACT: The origin and persistence of AF result from a complex interaction between triggers, autonomic nervous system, substrate, and factors involved in atrial remodelling. The pathophysiology of AF differs from one patient to another, but recent advances have helped us to understand more about involved mechanisms and to translate this knowledge into improvements in AF therapy. An illustration is the elimination of triggers within pulmonary veins by means of catheter ablation. Dealing with structural atrial remodelling and atrial fibrosis remains still a great challenge. Solving these problems could help us to develop new approaches to AF prevention and treatment.Annales de cardiologie et d'angeiologie 12/2009; 58 Suppl 1:S6-10. · 0.21 Impact Factor -
Article: Sudden death expertise centre: a multi disciplinary approach for sudden death.
Eloi Marijon, Wulfran Bougouin, Alain Cariou, Daniel Jost, Pierre Carli, Alain Combes, Antoine Leenhardt, Xavier JouvenArchives of cardiovascular diseases 11/2011; 104(11):555-7. · 0.66 Impact Factor -
Article: Guidelines issued by the French Society of Cardiology concerning the competence, performance and environment required in the practice of diagnostic and interventional cardiac electrophysiology.
Olivier Piot, Frédéric Anselme, Serge Bovéda, Michel Chauvin, Jean-Claude Daubert, Pascal Defaye, Jean-Claude Deharo, Daniel Gras, Jean-Sylvain Hermida, Salem Kacet, Didier Klug, Antoine Leenhardt, Jean-Yves le Heuzey, Philippe Mabo, André Pisapia, Nicolas Sadoul, Michèle Salvador-Mazenq, Serge CazeauArchives of cardiovascular diseases 11/2011; 104(11):586-90. · 0.66 Impact Factor -
SourceAvailable from: Pascale Guicheney
Article: Response to the letter by kattygnarath et Al.
Darouna Kattygnarath, Svetlana Maugenre, Nathalie Neyroud, Elise Balse, Carole Ichai, Isabelle Denjoy, Gilles Dilanian, Raphaël P Martins, Véronique Fressart, Myriam Berthet, Jean-Jacques Schott, Antoine Leenhardt, Vincent Probst, Hervé Le Marec, Bernard Hainque, Alain Coulombe, Stéphane N Hatem, Pascale GuicheneyCirculation Cardiovascular Genetics 10/2011; 4(5):e23. · 6.11 Impact Factor