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Answer added in Bioinformatics and Computational Biology6 Comparing Biological PathwaysBy Amy Wafa Daali · University of Texas at San AntonioAmy Wafa Daali · University of Texas at San AntonioThank you all for your feedback & comments!Thank you all for your feedback & comments!Following
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Answer added in Bioinformatics and Computational Biology6 Comparing Biological PathwaysBy Amy Wafa Daali · University of Texas at San AntonioAmy Wafa Daali · University of Texas at San AntonioThank you Rajashri , I wil give it a try!Thank you Rajashri , I wil give it a try!Following
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Answer added in Bioinformatics and Computational Biology6 Comparing Biological PathwaysBy Amy Wafa Daali · University of Texas at San AntonioAmy Wafa Daali · University of Texas at San AntonioSorry for not being so specific, the data is mRNA time series microarray data derived from virus infection of human cells collected at different times... [more]Sorry for not being so specific, the data is mRNA time series microarray data derived from virus infection of human cells collected at different times t=[0 1 3...]. Where time 0hr is the Control data (no virus infection). I'm looking at the fold ratio change of 1hr/0hr , 3hr/0hr ... I end up having pathways with these log2(ratio). I'm trying to find a metric to compare these pathways since taking the average of all fold changes within a pathway dosen't really make sense. Since in a single pathway, we can have genes that are upregulated and others that are downregulated...I'm looking for a reliable score that reflects the status of each pathway.Following
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Question asked in Bioinformatics and Computational Biology6 Comparing Biological PathwaysDoes anyone know how to compare between different biological pathways with different sizes and different log2 Ratio values? Say I have : pathway 1 =[... [more]Does anyone know how to compare between different biological pathways with different sizes and different log2 Ratio values? Say I have : pathway 1 =[ 5 3 2 -0.1 -0.01 -0.2 0.6 0.5 ] pathway 2=[ 5 3 2 -0.1] A positive value means a gene is upregulated whereas a negative value means a gene is downregulated.By Amy Wafa Daali · University of Texas at San AntonioFollowing
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Answer added in Gene Regulation3 KSHV-Host Interaction database?By Amy Wafa Daali · University of Texas at San AntonioAmy Wafa Daali · University of Texas at San AntonioThank you for your help!Thank you for your help!Following