Which genes (gene sets) plays the most important roles in lung cancer or colon cancer?

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• 
  Bernhard Biersack · University of Bayreuth

  Mutations in the ras gene occur in 40-50% of colon and lung carcinomas. Myc amplifications and Her2 overexpression also occur frequently in colon cancers.

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  Mutations in the ras gene occur in 40-50% of colon and lung carcinomas. Myc amplifications and Her2 overexpression also occur frequently in colon cancers.

  Feb 29, 2012
• 
  Zhenyu Wang · University of Oxford

  Thanks!

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  Thanks!

  Mar 1, 2012
• 
  Zhenyu Wang · University of Oxford

  Btw, how do you get these information? From literature or lab work?

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  Btw, how do you get these information? From literature or lab work?

  Mar 1, 2012
• 
  Alberto Moran · Complutense University of Madrid

  But those genes are not very useful for colorectal cancer diagnosis, as they are usually mutated in many different tumours...

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  But those genes are not very useful for colorectal cancer diagnosis, as they are usually mutated in many different tumours...

  Mar 1, 2012
• 
  Bernhard Biersack · University of Bayreuth

  There are some papers about it. Well, I recently gave a talk on the therapy of Ras-mutated cancers. COX-2 levels are also usually increased in colon cancers in contrast to normal colon tissues.

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  There are some papers about it. Well, I recently gave a talk on the therapy of Ras-mutated cancers. COX-2 levels are also usually increased in colon cancers in contrast to normal colon tissues.

  Mar 1, 2012
• 
  Hossam Murad · Atomic Energy Commission of Syria

  the APC gene

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  the APC gene

  Mar 20, 2012
• 
  Axel Grothey · Mayo Foundation for Medical Education and Research

  Take a look at the recent publication of the TCGA (The Cancer Genome Atlas) in Nature.

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  Take a look at the recent publication of the TCGA (The Cancer Genome Atlas) in Nature.

  Sep 13, 2012