Having an a knowledge of the LC 10 or LC 90 in addition to the LC50 of a drug, substance or toxicant gives a lower and upper limit of toxicity or drug activity where applicable.
it is particularly useful when a substance does not follow a dose response pattern i.e. where toxicity or drug activity does not necessarily increase with increasing concentrations.
LC50s can also describe aqueous concentrations used in vivo animal exposures as in zebrafish and medaka (small teleost fish models). It would not be an LD50 because you cannot be certain of the exact dose that each fish receives, especially when LD50s are reported terms of mass (mg/kg, etc).
I agree with Laura.
Md. Atiqur Rahman
Blake M Warner
University of Pittsburgh
National Environmental Engineering Research Institute
Arathi (Sesha) Paluri
Wright State University
Asif Khurshid Qazi
Indian Institute of Integrative Medicine
University of Port Harcourt
Maharani Lakshmi Ammanni College for Women
G. B. Pant University of Agriculture and Technology, Pantnagar
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