Question

Is organic chemical synthesis in supercritical fluid media presently available commercially?

I am interested in starting a project involving synthesis of palm-based oleochemicals in supercritical fluid carbon dioxide as presently all synthesis used solvents.

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All Answers (10)

  • Jin-Quan Wang · Chinese Academy of Sciences
    Several case
  • Witold Neugebauer · Université de Sherbrooke
    Carbon dioxide and water are the most commonly used supercritical fluids, being used for decaffeination. I don't think they are available commercially but you ask company who does it and you will get an answer.
  • Zhiyong Wang · University of Science and Technology of China
    i don't know. At this time, I have not heard that commercial supercritical fluid media
  • Gellert Sipos · Thales Group
    The Jasco have a supercritical CO2 pump.
  • Lasse Greiner · Hochschule Mannheim
    It depends on the operation you have in mind and which SCF. Continuous flow can be easily adopted with supercritical flow chromatography equipment. This is mainly carbon dioxide but can be adopted to al room temperature non-compressible liquids.
    Would you provide more detail what you have in mind? Batch/continuous, nature of SCF, extraction or reaction, catalysed etc.?
  • Bonnie tay yen ping · Malaysian Palm Oil Board
    I am still very new to organic synthesis work actually and very new to supercritical fluid technology so i am wondering is there any experts in this field who can give suggestion or advice what kind of reaction chamber i should use . whether the chamber with supercritical fluid media can allow use of catalyst as well. What i have in mind is converting the already established palm-based oleochemical synthesis route (previously using solvent) to supercritical fluid. Thanks to Dr. Lasse Grenier for his comments ,i find it helpful.
  • Atsushi Kobayashi · Tohoku University
    I used to study enzyme reactions in supercritical fluoroform. http://dx.doi.org/10.1021/ja0169522 http://dx.doi.org/10.1039/b104913p Fluoroform can solubilize many lipid such as triglycerides. However, I am not sure this solvent is commercially available recently.
  • Lasse Greiner · Hochschule Mannheim
    Flouroform is commercially available, alas not cheap. Also, many of the scF are greenhouse gases. CO2 is a notable exception. For batch application and lab trials commercially available reaction autoclaves (Parr, Büchi, Premex etc.) can be used. If you have no practical experience I strongly recommend to gain some practical experience somewhere. There are high pressures of compressible gases involved which may behave unexpected.
  • Please go foe adsorption techenic
  • Bonnie tay yen ping · Malaysian Palm Oil Board
    hI Mr Atakari, i dont understand your answer, can you elaborate, thank you

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