Question

DNMT1 clone and expression

Who was the first person to clone the DNMT1 gene?

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  • Deveroux Ferguson · Mount Sinai School of Medicine
    This reference may prove helpful

    Yen RW, Vertino PM, Nelkin BD, Yu JJ, el-Deiry W, Cumaraswamy A, Lennon GG, Trask BJ, Celano P, Baylin SB (June 1992). "Isolation and characterization of the cDNA encoding human DNA methyltransferase". Nucleic Acids Res 20 (9): 2287–91. doi:10.1093/nar/20.9.2287. PMC 312343. PMID 1594447.
  • Angus Wilson · New York University USA
    Not an expert on this but you might also want to dig back a little further to the work of Tim Bestor who reported cloning cDNA for mouse DNMT1 in 1988.

    Bestor, T., Laudano, A., Mattaliano, R. and Ingram, V. (1988) Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. J. Mol. Biol., 203, 971–983.
    PMID: 3210246

    Bestor TH. Cloning of a mammalian DNA methyltransferase. Gene. 1988 Dec 25;74(1):9-12. PMID: 3248734

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