Animal model to study Vascular regeneration

Hi, I am planning to study vascular repair using Carotid artery injury and injecting the cells locally at the site of injury. I would like to know which is the best method to use? If i perform wire injury and inject the cells, i have my own doubts whether cells retain in the injured area! Is it an advantage to use carotid ligation model and inject cells locally? Time point for the experiment is 21days to 28days after injury and injection of cells.