Asian Journal of Pharmaceutical and Biological Research (AJPBR)

Journal description

Published by Young Pharmaceutical and Biological Scientist Group, country India, Quaterly journal

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Website Pharmaceutical sciences, Biological Sciences, Medical sciences
ISSN 2231-2218
Material type Orignial articles, review articles, Short communication, on Pharmacy sciences, Biological Sciecnes Medicine Sciences
Document type Journal

Publications in this journal

  • Asian Journal of Pharmaceutical and Biological Research 01/2014;
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    ABSTRACT: Subdural empyema (SE) is a life-threatening infection, it accounts for about 15-22% of focal intracranial infections. The mortality rate approached 100% before the introduction of penicillin and has declined since that time. We report a case of 10-mo-old infant who was admitted with high grade fever and convulsion with diagnosis of bacterial meningitis, after 10 days due to continue of fever, Vomiting and revealed disturbance of neurological examination, CT showed a low density area in the hemispheric area. She underwent urgent surgical drainage of subdural empyema (Burr hole) followed by antibiotics therapy. She was discharged from our hospital without neurologic deficit
    Asian Journal of Pharmaceutical and Biological Research 05/2013; 3(3):74-77.
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    ABSTRACT: ABSTRACT: Meningitis is one of the most common CNS emergencies. Aseptic meningitis is the most prevalent type of meningitis. The clinical features initially are not specific. Enteroviruses have more than 60 serotypes which are culpable for more than 85% of aseptic meningitis. Polymerase chain reaction (PCR) is a highly sensitive test for detection of viruses; therefore by using of this method, diagnosis of aseptic meningitis can be achieved rapidly. We can use this method even for detection of viral types, and therefore choosing the best treatment. We have evaluated 47 cases of highly suspicious to meningitis in a cross sectional manner by PCR method. We found 4 positive cases for enterovirus. It seems that, by using of PCR method we can differentiate aseptic meningitis easily and rapidly, so decreasing costs can be achieved by this method. Key words: PCR, Enterovirus, Aseptic Meningitis, Bacterial Resistance
    Asian Journal of Pharmaceutical and Biological Research 05/2013; 3(3):85-87.
  • Asian Journal of Pharmaceutical and Biological Research 04/2013;
  • Asian Journal of Pharmaceutical and Biological Research 03/2013; 3(1):8-12.
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    ABSTRACT: ABSTRACT: Mesenteric cysts are rare and usually without specific abdominal finding. We report a case of 25- hours- old newborn, who came with the presentations of an intestinal obstruction which was found during operation. It was a mesenteric cyst and atresia of the small bowel causing intestinal obstruction. The cyst with the adjacent loop was resected and intestinal continuity was restored. Mesenteric cyst was compatible with enteric duplication type in microscopic report. Key words: Mesenteric Cyst, Neonate, Intestinal Obstruction
    Asian Journal of Pharmaceutical and Biological Research 03/2013; 3(2):55-57.
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    ABSTRACT: Objective: The present study was designed to evaluate some hormonal impact on menstrual cycle pattern of HIV infected women of child bearing age and to assess whether the changes observed are directly related to HIV infections. Methods: This was a prospective study that involved 214 female participants aged between 15 and 45 years conducted at Nnamdi Azikiwe University Teaching Hospital Nnewi. Based on the result of the screening, they were grouped as: HIV seropositive subjects (n=79), HIV seropositive subjects on Anti Retroviral Therapy (ART) (n=80) and control HIV seronegative subjects (n=55). After due consent, a detailed medical history was obtained using questionnaire. Blood samples collected from the participants were used for double HIV seroreactivity by rapid immunoassay and immunochromatographic techniques and hormonal assay using immunoenzymometric method. Results: Menstrual abnormalities were reported in 76% of women in the study group. Secondary amenorrhea was observed in 32(40.5%) of HIV subjects, 20(25%) of HIV subjects on ART when compared with 1(1.8%) in control subjects. Hypomenorrhea was observed in 16(20.3%) of HIV subjects, when compared with 1(1.8%) observed in control subjects. Hypermenorrhea was observed in 18(22.5%) of HIV subjects on ART when compared with the 1(1.8%) in control subjects. The mean (±SD) serum FSH ( IU/ml) and LH ( IU/ml) were significantly higher at follicular and luteal HIV subjects whether on ART or not when compared with their corresponding control subjects (P<0.05 respectively). The mean (±SD) serum Prolactin (ng/ml) at follicular HIV subjects was significantly higher when compared with the follicular control subjects (P<0.05). Similar observation was made in luteal HIV subjects when compared with the counterparts on ART (P<0.05). Conclusion: the study suggests a marked hormonal impact on the menstrual cycle pattern observed in the study subjects which may be attributed to HIV infections and ART as well. Key Words: Menstrual Pattern, Irregularities, HIV, Hormones
    Asian Journal of Pharmaceutical and Biological Research 01/2013; 3(1):29-33.
  • Asian Journal of Pharmaceutical and Biological Research 01/2013; 3(1):18-23.
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    ABSTRACT: ABSTRACT: Measles is the most deadly of all childhood rash/fever illnesses. The disease spreads very easily, so it is important to be protected against infection. Extensive vaccination is the best way to prevent measles. We conducted a descriptive study conducted in 5 health service centers of Bandar Abbas and 194 vaccinated children from May 2012 to December 2012. Target groups were children with 13 to 18 months age who received first MMR vaccine (Group A) and 19 to 24 month's age children who received first and second MMR vaccine (Group B). We evaluated the anti-measles anti-body ELIZA method in both groups 1 to 6 months after vaccination. The results of this study showed that 1 to 6 month after first and second MMR vaccination, highly effective immunity against measles (98.96%) is acquired In 137 children (male, female) of group A, mean titer of anti-measles antibody was 57.69 IU/ml and in 58 children (male, female) in group B, was 55.70. Anti-measles antibody under 1.2 IU/ml considered as seronegative. Only two children in group A had insufficient immunity against measles. We found no significant difference between serum level of anti-measles antibody in two groups of children and also no remarkable correlation between gender and serum level of anti-measles anti-body found.
    Asian Journal of Pharmaceutical and Biological Research 01/2013; ISSN: 2322-4789(Asian J. Med. Pharm. Res. 3(4): 176-178, 2013):176-178.