ChemPlusChem

Journal description

ChemPlusChem is a peer-reviewed journal tailored to multidisciplinary chemistry and materials researchers from across the world. Fully comprehensive in its scope, ChemPlusChem publishes original papers covering at least two different aspects (subfields) of chemistry or one of chemistry and one of another scientific discipline (one chemistry topic plus another one, hence the title ChemPlusChem).

Current impact factor: 3.24

Impact Factor Rankings

2015 Impact Factor Available summer 2015
2013 / 2014 Impact Factor 3.242
2012 Impact Factor

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5-year impact 0.00
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ISSN 2192-6506

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Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: Surface modification of silica nanoparticles (SiNPs) inside living cells was conducted by using the copper-free bioorthogonal click reaction to evaluate the effects of surface chemical structures on dynamic behavior and excretion of SiNPs. The results demonstrated the spatial translocation of intracellular SiNPs to the plasma membrane upon surface modification in situ with phospholipids. Moreover, the extent and kinetics of excretion of the SiNPs from inside the cell were enhanced by modification.
    ChemPlusChem 03/2015; DOI:10.1002/cplu.201402436
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    ABSTRACT: Nanoparticulate bimodal porous silica-based materials have been prepared through a surfactant-assisted procedure by using a simple template and starting from inexpensive sodium silicate as silicon source. Different procedural variables, such as pH or the nature and concentration of the surfactant, have been explored to optimize the preparative protocol, which allows, in turn, improved understanding of the formation process. The final bulk materials (called UVM-10 or M-UVM-10) are formed by pseudomorphic transformation of fresh silica-based xerogels under mild basic conditions. The UVM-10 architecture is constructed from small mesoporous nanoparticles, the aggregation of which generates a disordered secondary 3 D pore system (large-meso/macropores) defined by interparticle voids. Modulation of the intraparticle mesopore size is achieved by using surfactants with variable tail lengths, while maintaining the same head group. Textural porosity has been handled independently by hydrothermally modifying the particle size of the reactive silica-based xerogel. By simply adding metal alkoxides to the initial reaction mixture, the preparative protocol allows for functionalizing the silica walls by incorporating relatively high proportions of homogeneously dispersed heteroelements, such as Al and Ti.
    ChemPlusChem 03/2015; DOI:10.1002/cplu.201402383
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    ABSTRACT: Two microporous complexes, [Zn(TATAB)(OCH3)]⋅2 H3O+ (1; TATAB=4,4′,4′′-[(1,3,5-triazine-2,4,6-triyl)tris(azanediyl)]tribenzoic acid), [Cu1.5(μ2-O)TATAB*] (2; TATAB*=4,4′-{[6-(dimethylamino)-1,3,5-triazine-2,4-diyl]bis(azanediyl)}dibenzoic acid) have been synthesized and characterized by elemental analysis, IR spectroscopy, UV absorption spectroscopy, and thermogravimetric analysis, and by powder XRD and single-crystal XRD analysis. Structural analyses revealed that complex 1 possesses a 3D porous framework with uncoordinated water molecules trapped in the pores; the dimensions of the channels are approximately 29.2×12.3 Å2. Complex 2 has a 3D microporous network structure. In addition, the surface photovoltage and photocatalytic activities were also studied. The photocatalytic properties of the two complexes were investigated by the decomposition of methylene blue under UV and visible-light irradiation. The results revealed that 2 possessea a higher photocatalytic activity than 1 under UV or visible-light irradiation. The potential semiconductor and dye degradation properties of complexes 1 and 2 may be widely applied in the fields of chemical semiconductors and environmental protection in the future.
    ChemPlusChem 03/2015; DOI:10.1002/cplu.201402374
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    ABSTRACT: A catalyst based on immobilization of tungstate ions (WO42−) inside the mesochannels of periodic mesoporous organosilica comprising bridged ionic liquid (1,3-bis(3-trimethoxysilylpropyl)imidazolium chloride) has been synthesized and characterized. This catalyst was then employed for the selective oxidation of organic sulfides to the corresponding sulfoxides or sulfones. The final synthesized catalyst was characterized by various techniques such as nitrogen sorption analysis, transmission electron microscopy, and thermogravimetric analysis. The catalyst was also applied to the selective oxidation of sulfides containing readily oxidizable functional groups such as hydroxyl, allylic, and even challenging aliphatic sulfides. Interestingly, it was found that on changing the reaction medium from aqueous methanol to aqueous acetonitrile, the product selectivity was changed successfully from sulfoxide to sulfone with good to excellent yields. Moreover, the catalyst can also be recovered and reused efficiently in nine subsequent reaction cycles without any remarkable decrease in the catalyst activity and selectivity.
    ChemPlusChem 03/2015; DOI:10.1002/cplu.201500010
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    ABSTRACT: The high capacity, excellent cyclability, and good rate capability of reduced graphene oxide (rGO) anchored with Bi2O3 nanocomposite for sodium-ion batteries is reported. A simple reduction method is adapted to deposit spherical Bi2O3 nanoparticles on the surface of rGO sheets. The surfactant cetyltrimethylammonium bromide (CTAB) plays a major role in controlling the morphology of the Bi2O3 nanoparticles. This Bi2O3@rGO nanocomposite has the advantages of high reversible capacity with a capacity retention (at high rate) of 70.2 % after 200 cycles at a current density of 350 mA g−1. This superior performance can be attributed to the fact that rGO sheets hamper the volume expansion of Bi2O3 nanoparticles and result in faster diffusion of Na+ ions (diffusion coefficient: 5.12×10−8 cm2 s−1) and smaller internal resistance (84.17 Ω) compared with pristine Bi2O3 nanoparticles. The results suggest that anchoring rGO sheets with metal oxides is one of the simplest ways to enhance the electrochemical performance of sodium-ion batteries.
    ChemPlusChem 03/2015; DOI:10.1002/cplu.201402394
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    ABSTRACT: Copper ferrite and palladium nanoparticles assembled on silica microparticles are prepared successfully and characterized by scanning electron microscopy, transmission electron microscopy, electron-dispersive X-ray analysis, X-ray diffraction, thermogravimetric analysis, atomic absorption spectroscopy, and infrared studies. The catalyst is applied effectively for the Sonogashira coupling reaction of aryl iodides and bromides under heterogeneous and phosphine-free reaction conditions. The reactions proceed at 50 °C with a low loading of palladium catalyst. The magnetically recoverable catalyst is recycled successfully for five consecutive runs with very small drops in catalytic activity.
    ChemPlusChem 03/2015; DOI:10.1002/cplu.201500015
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    ABSTRACT: In the continuing search for novel, biologically effective heterocyclic agents, several methods for the synthesis of 2-heteroaryl-[1,2,4]triazolo[1,5-c]quinazoline-5(6 H)-thiones have been developed: thiolation of oxo derivatives, [5+1] cyclocondensation of [2-(3-heteroaryl-[1,2,4]triazol-5-yl)phenyl]amines with carbon disulfide, potassium ethyl xanthogenate, or aryl isothiocyanates, and in situ reaction of 2-isothiocyanatobenzonitrile with hydrazides. A series of N-R-2-[(2-heteroaryl-[1,2,4]triazole-[1,5-c]quinazoline-5-yl)thio]acetamides were obtained by aminolysis of the corresponding acetic acids and alkylation of potassium thiolates with N-R-2-chloroacetamides. It was established that some potassium thiolates, 4 a–4 d, 4 h, and 4 i, had high antibacterial activity against Staphylococcus aureus with a minimum inhibitory concentration of 12.5 μg mL−1 and minimum bactericidal concentration of 25 μg mL−1, which exceeded the values for trimethoprim. In addition, {2-[3-(1 H-indole-2-yl)-1 H-1,2,4-triazol-5-yl]phenyl}amine 2 i was investigated in the concentration range 100–0.01 μM at 59 lines of nine cancer cell types, and showed a mean effective concentration at 3.12–7.03 μM and cytotoxic effect at 15.56–67.38 μM. The possible mechanisms of activity were predicted by molecular docking studies to S. aureus dihydrofolate reductase and epidermal growth factor receptor kinase.
    ChemPlusChem 03/2015; DOI:10.1002/cplu.201500051
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    ABSTRACT: Nanostructured biosilica produced by Thalassiosira weissflogii diatoms is covalently functionalized with the cyclic nitroxide 2,6,6-tetramethylpiperidine-N-oxyl (TEMPO), an efficient scavenger of reactive oxygen species (ROS) in biological systems. Drug delivery properties of the TEMPO-functionalized biosilica are studied for Ciprofloxacin, an antimicrobial thoroughly employed in orthopedic or dental implant related infections. The resulting TEMPO-biosilica, combining Ciprofloxacin drug delivery with anti-oxidant properties, is demonstrated to be a suitable material for fibroblasts and osteoblast-like cells growth.
    ChemPlusChem 03/2015; DOI:10.1002/cplu.201402398
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    ABSTRACT: A combined experimental and quantum chemical study has been performed on rac- and meso-[Zr{1-Me2Si(3-η5-C9H5Et)2}Cl2] (rac- and meso-1) and their hydrogenated forms (rac- and meso-2) to understand ligand effects and guide ligand design for more active ansa-bis(indenyl) zirconocenes for the polymerisation of ethylene. The rac-ansa-zirconocene rac-[Zr(1-Me2Si{3-Et-(η5-C9H9)}2)Cl2] (rac-2) has been prepared and fully characterised by NMR spectroscopy and elemental analysis. The molecular structure of rac-2 has also been determined by single-crystal XRD. The behaviour of the catalysts was analysed in the polymerisation of ethylene and higher activities were obtained for rac-1 and its hydrogenated form rac-2. The influence of the stereochemistry and hydrogenation of the indenyl ligand on the experimental activities has been evaluated by computational studies. The differences along the reaction pathway are dominated by changes in the relative stabilities of the catalytic intermediates. A hybrid density functional B3LYP study, in the presence of toluene as the solvent, indicates that the rac forms give rise to more active species than their meso counterparts. The hydrogenation of the rac forms is a very promising approach to increase activities in polymerisation, in contrast to the meso forms. Finally, the global mechanism rate constants for the polymerisation reaction for each metallocene were calculated by using the thermodynamic formulation of transition-state theory to complement the computational study.
    ChemPlusChem 03/2015; DOI:10.1002/cplu.201500008
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    ABSTRACT: Reported is the synthesis of 3D hierarchical structures based on one-dimensional MnO2 nanobuilding blocks (nanorods, nanowires, and nanoneedles) by means of a facile and scalable coprecipitation method and their use as electrodes for the assembly of all-solid-state supercapacitors. Asymmetric devices were also assembled by using these nanostructured MnO2 materials as the positive electrode and reduced graphene oxide (rGO) as the negative electrode with a polymeric gel electrolyte. The asymmetric cells successfully extend the working voltage windows beyond 1.4 V and allowed for a maximum voltage of 1.8 V. An asymmetric device based on hierarchical nanoneedle-like MnO2 and rGO achieved a maximum specific capacitance of 99 F g−1 at a scan rate of 10 mV s−1 with a stable operational voltage of 1.8 V. This high value allowed for a large specific energy of 24.12 Wh kg−1.
    ChemPlusChem 02/2015; DOI:10.1002/cplu.201500054
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    ABSTRACT: The design and the preparation of a small library of 1,4-diphenyl-1,2,3-triazole derivatives is reported, with the aim to obtain a new class of Hedgehog pathway inhibitors. The smoothened protein is part of the hedgehog signaling pathway that is inhibited by the lead compound Vismodegib. Based on molecular modeling simulations, seven triazole derivatives of Vismodegib are synthesized and their biological effect on different endothelial, cancer, and cancer stem cell lines is reported.
    ChemPlusChem 02/2015; DOI:10.1002/cplu.201402435
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    ABSTRACT: Pyridinium gemini surfactants with hexadecyl chains linked to nitrogen atoms and a tuned aliphatic spacer that bridges the two pyridinium polar heads in 2,2′-positions have been synthesized and characterized. A multitechnique approach allowed us to study the aggregation behavior, using conductivity, surface tension, and fluorescence. Graphs of the specific conductivity (κ) versus the surfactant molar concentration (C), and graphs of the molar conductivity (Λ) versus C0.5 suggest pre-aggregation phenomena of these amphiphiles at very low concentration. The trends of Amin as a function of the spacer length confirm the hypothesis of a conformational change of the molecule with four methylene groups as spacer owing to stacking interactions between the two pyridinium rings mediated by the counterion. Moreover, the trends of Amin and counterion binding (β) suggest that the spacer must be longer than eight carbon atoms to fold efficiently toward the micellar core. The opportunity to tune the surfactant structure and aggregation properties make those surfactants—particularly the long-chain ones for which the DNA complexing ability was shown by means of atomic force microscopy (AFM) imaging—desirable candidates for gene-delivery experiments.
    ChemPlusChem 02/2015; DOI:10.1002/cplu.201500007
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    ABSTRACT: A tungsten peroxo complex stabilized by the bidentate picolinato ligand has been synthesized and then immobilized successfully on imidazole-functionalized silica. The immobilized tungsten-based catalyst was employed as an efficient catalyst for the one-pot synthesis of β-alkoxy alcohols from olefins and methanol with H2O2. Regarding the catalyst evaluation and the results of characterization by the various methods, it was demonstrated that the immobilization of tungsten peroxo complex was highly temperature-dependent. The tungsten peroxo complex can dissociate and diffuse into the liquid phase at reaction temperature, resulting in a homogeneous reaction. Nevertheless, the catalytically active species was anchored on the imidazole-functionalized silica by hydrogen bonding as the temperature was lowered to 0 °C after the reaction, which thus offered a highly effective approach for recycling the catalyst for consecutive cycles. In addition, various olefins can be converted to the corresponding β-alkoxy alcohols with good conversion and selectivity under relative mild conditions by H2O2.
    ChemPlusChem 02/2015; DOI:10.1002/cplu.201402456
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    ABSTRACT: The unwanted fouling of surfaces by ionic adsorption has received little research attention. In this context, ultrathin organic adlayer surface chemistry—featuring monoethylene glycol based molecular residues—is described that is capable of noticeably decreasing the rate of anion depletion from solution. The strategy is exemplified with glass as the substrate material and fluoride as the anion foulant.
    ChemPlusChem 02/2015; DOI:10.1002/cplu.201500027
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    ABSTRACT: Two-dimensional comprehensive gas chromatography (GC×GC) coupled with mass detection was used as a tool for biosynthetic studies of bumblebee pheromones. Prior to biosynthetic experiments, the chromatographic behaviour of isotopically modified esters in the GC×GC system as well as their behaviour in mass detection was studied. The male marking pheromones of Bombus lucorum, Bombus lapidarius and Bombus terrestris were investigated. Main pheromonal components are ethyl tetradec-9-enoate (53 %) and ethyl dodecanoate (6 %) in B. lucorum, hexadec-9-en-1-ol (52 %) and hexadecan-1-ol (31 %) in B. lapidarius, and 2,3-dihydrofarnesol (58 %) and ethyl dodecanoate (15 %) in B. terrestris. The research strategy was based on 1) in vivo incubation of isotopically (2H, 13C) modified fatty acids (FAs) and analysis of their metabolites and 2) feeding experiments with 2H- and 13C-labelled FAs mixed with food. It was observed that labelled FAs were modified into the most abundant aliphatic compounds present in labial gland secretions. In feeding experiments, the labelled FAs were transformed into pheromone components. Transport of the FA precursors from the fat body through haemolymph was confirmed. The results show that FAs, stored in the form of triacylglycerols in the fat body, are likely to participate in the biosynthesis of some aliphatic pheromone components.
    ChemPlusChem 02/2015; DOI:10.1002/cplu.201402420
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    ABSTRACT: A series of one-dimensional (1D) double-zigzag ({[Zn(papx)2(H2O)2](ClO4)2}n (x=so 1, sc 3, oc 5, and soc 7) and 2D polyrotaxane ([Zn(papx)2(ClO4)2]n (x=so 2, sc 4, oc 6, and soc 8) frameworks are synthesized by the reactions of Zn(ClO4)2 with equimolar amounts of papx (i.e., papso=1/2paps+1/2papo, papsc=1/2paps+1/2papc, papoc=1/2papo+1/2papc, and papsoc=1/3paps+1/3papo+1/3papc; paps=N,N′-bis(pyridylcarbonyl)-4,4′-diaminodiphenyl thioether, papo=N,N′-bis(pyridylcarbonyl)-4,4′-diaminodiphenyl ether, papc=N,N′-(methylenedi-p-phenylene)bispyridine-4-carboxamide). The new frameworks are isolated and characterized by single-crystal and powder X-ray diffraction studies, elemental analysis, and 1H NMR spectroscopy. In addition, synthesis and structural characterization of 2D polyrotaxane frameworks of [Cu(papx)2(ClO4)2]n (x=s 9, o 10, and c 11) by the reaction of Cu(ClO4)2 with the respective dipyridylamide ligands are carried out. Based on the PXRD experiments, upon heating, the double-zigzag frameworks of 1, 3, 5, and 7 undergo structural transformation to give the respective polyrotaxane frameworks of 2, 4, 6, and 8. Moreover, grinding the solid samples of 2, 4, 6, and 8 in the presence of moisture also result in the total conversion back into the double-zigzag frameworks of 1, 3, 5, and 7, respectively. Remarkably, grinding the solid samples of polyrotaxane frameworks of 9 and 10 in the presence of moisture fails to induce a structural transformation process.
    ChemPlusChem 02/2015; DOI:10.1002/cplu.201402453
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    ABSTRACT: A new chalcone-based probe for the chromofluorogenic sensing of trivalent (Al3+, Fe3+, Cr3+, Ga3+, In3+ and As3+) over mono- and divalent cations and anions is reported. In the presence of trivalent metal cations, the probe was able to display a remarkable color change from yellow to colorless that was clearly visible to the naked eye. Also, the initial strong yellow emission was gradually quenched and substituted by a weakly shifted band.
    ChemPlusChem 02/2015; DOI:10.1002/cplu.201500042
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    ABSTRACT: The selective synthesis of various dideuterochalcones as potentially bioactive deuterium-labeled products is presented, by means of the highly controlled partial deuteration of antidiabetic chalcone derivatives. The benefits of continuous-flow processing in combination with on-demand electrolytic D2 gas generation has been exploited to avoid over-reaction to undesired side products and to achieve selective deuterium addition to the carbon–carbon double bond of the starting enones without the need for unconventional catalysts or expensive special reagents. The roles of pressure, temperature, and residence time proved crucial for the fine-tuning of the sensitive balance between the product selectivity and the reaction rate. The presented flow-chemistry-based deuteration technique lacks most of the drawbacks of the classical batch methods, and is convenient, time- and cost-efficient, and safe.
    ChemPlusChem 02/2015; DOI:10.1002/cplu.201402426
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    ABSTRACT: A two-step synthesis was developed to fabricate Ag/AgBr necklace-like nano-heterostructures at room temperature. Multiple crystalline Ag nanowires were used as templates following an oxidation route in situ from CuBr2 to create Ag/AgBr heterostructures. Polyvinylpyrrolidone can govern the formation of one-dimensional Ag/AgBr necklace-like nano-heterostructures. The composition of the heterostructures was adjusted by changing the amount of CuBr2. Experimental conditions were optimized. In particular, the concentration and injection rate of copper bromide solution play an important role in controlling the oxidation of the Ag nanowires for the purpose of adjusting the morphology of the Ag/AgBr heterostructures. As a result, the heterostructures with 40 mol % AgBr displayed a regular necklace-like morphology. Under visible-light irradiation, Ag/AgBr necklace-like heterostructures with AgBr molar ratios of 10 to 50 % exhibited enhanced plasmonic photocatalytic performance for the degradation of organic pollutants (methyl orange, methylene blue, and rhodamine B).
    ChemPlusChem 02/2015; DOI:10.1002/cplu.201500032
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    ABSTRACT: A low-cost hydrothermal method was used to synthesize high-purity bipyramidal single-crystals of TiO2 enclosed with high percentage of (101) facets. The oriented attachment behavior can be controlled by fine tuning the reaction temperature. This played an important role in determining the crystal growth along [001] direction resulting in the self-assembly of the bipyramid crystals into connected ones to form single-crystal nanrods without the loss of surface area. In addition, the relationship between oriented attachment and the photovoltaic performance of such anatase TiO2 nanocrystals in photoanodes of DSCs was investigated. The highly oriented sample reached a maximum overall energy conversion efficiency of 8.63 %. These results further illustrated that the highly oriented samples have superior charge transport ability derived from the enhanced long-range atomic arrangement with reduced grain boundaries and comparable uptake of dye molecules.
    ChemPlusChem 02/2015; DOI:10.1002/cplu.201402449