ChemPlusChem

Description

ChemPlusChem is a peer-reviewed journal tailored to multidisciplinary chemistry and materials researchers from across the world. Fully comprehensive in its scope, ChemPlusChem publishes original papers covering at least two different aspects (subfields) of chemistry or one of chemistry and one of another scientific discipline (one chemistry topic plus another one, hence the title ChemPlusChem).

Impact factor 3.24

  • 5-year impact
    0.00
  • Cited half-life
    0.00
  • Immediacy index
    0.00
  • Eigenfactor
    0.00
  • Article influence
    0.00
  • Website
  • ISSN
    2192-6506

Publications in this journal

  • Giulia Tuci, Lapo Luconi, Andrea Rossin, Francesco Baldini, Stefano Cicchi, Sara Tombelli, Cosimo Trono, Ambra Giannetti, Ilse Manet, Stefano Fedeli, Alberto Brandi, Giuliano Giambastiani
    [Show abstract] [Hide abstract]
    ABSTRACT: Efforts have been made in recent years to develop novel functionalisation protocols aimed at imparting multimodality and improved properties to complex carbon-based nanostructures. The incorporation of cleavable bonds to the nanomaterial surface for the controlled release (or exchange) of specific molecules under appropriate chemical and biological settings is relatively unexplored. The design and synthesis of a hetero-bifunctional linker joining a “cleavable” disulfide moiety for the covalent anchoring of a wide range of thiol end-capped (bio)molecules and a “clickable” terminal acetylene group is described. The strategy is based on the well-established copper-mediated acetylene–azide coupling reaction between the acetylene linker and single-walled carbon nanotubes decorated with phenylazido pendant arms. As a result, easily “post-derivatisable” and traceable nanostructured platforms containing a linking group potentially available for a wide range of biological probes are prepared and completely characterised.
    ChemPlusChem 01/2015;
  • Cristina Flox, Javier Rubio‐Garcia, Marcel Skoumal, Javier Vázquez‐Galván, Edgar Ventosa, Joan Ramon Morante
    [Show abstract] [Hide abstract]
    ABSTRACT: A new positive electrolyte formulation for all-vanadium redox flow batteries (VFRB) with a significant improvement in electrochemical properties is reported in this communication. A 5 KDa poly(ethyleneimine)-based dendrimer (dPEI) demonstrates enhanced performance when used as an additive for positive electrolytes in VFRB. A thermal stability test at 40 °C shows that the dPEI additive prevents the precipitation of VO2+ over 720 h. The optimum concentration of the dPEI additive was as low as 0.6 % (weight per volume of electrolyte), leading to a cost-effective solution in terms of a 38 % increase in energy density (18 Wh L−1) with respect to the additive-free system (ca. 13 Wh L−1). Moreover, this innovative electrolyte performance remains stable at 88 % in energy efficiency over a wider operational temperature (up to 60 °C) while retaining the energy density.
    ChemPlusChem 01/2015;
  • [Show abstract] [Hide abstract]
    ABSTRACT: The properties of mesoporous silica nanoparticles (MSN) (biocompatibility, surface area, particle diameter, mesoporous structure, and ease of functionalization) are reviewed regarding their benefits for the construction of cancer-targeting drug delivery systems, with an overview of literature reports within this research area. Intrinsic properties characteristic of tumor tissues (enhanced permeability and retention effect, overexpressed receptors, and acidic extracellular pH) are further discussed which can be utilized for cancer targeting. Recent literature reports are also accounted concerning MSN-based cancer targeting that takes advantage of characteristics of the tumor environment and also nanotherapeutics capable of stimulus (acidification, exposure to light irradiation, magnetic field) responsive drug delivery. Finally, gene therapy approaches for cancer treatment and MSN-based gene delivery vectors are reviewed. The research on mesoporous silicates possesses great potential for the development of complex multipurpose nanotherapeutics for simultaneous application in effective targeted treatment and imaging of cancer tissues.
    ChemPlusChem 01/2015;
  • [Show abstract] [Hide abstract]
    ABSTRACT: Magnetic iron oxide/carbon nanotube (MI–CNT) hybrids have been successfully synthesized through a simple solid-phase method by using as-prepared CNTs (APCNTs). To further enhance the adsorption capacity for AsIII, MI–CNTs were subsequently functionalized by using an amino acid derivative (glutathione (GSH)) through a facile chemical route. CNTs not only act as a support for iron oxide but also significantly contribute to arsenic removal. The resulting GMI–CNTs possess simultaneously a high adsorption capacity and desirable magnetic properties, thus making them promising for use as an adsorbent to remove AsIII with significantly enhanced adsorption capacity (19.12 mg g−1) and desired magnetic separation properties (Ms=27.3 emu g−1). Adsorption studies indicated that the active sites on the surface of GMI–CNTs for AsIII are heterogeneous owing to the multiphase of Fe and the GSH functionalization. Therefore GMI–CNTs can potentially be used as a practical adsorbent for the decontamination of AsIII in water. The results of this study are highly important for practical applications of as-prepared CNTs that contain catalyst nanoparticles.
    ChemPlusChem 01/2015;
  • [Show abstract] [Hide abstract]
    ABSTRACT: On the basis of preliminary DFT calculations, p-type semiconducting polymers based on 2,7-substituted xanthene building blocks that show a high degree of planarity were designed. The synthesis, electrochemical characterization, and theoretical modeling of 2,7-bis(thiophen-2-yl)-9,9-dimethylxanthene (1) and 2,7-bis(3-hexylthiophen-2-yl)-9,9-dimethylxanthene (2) is described. The synthetic procedure is based on the incorporation of thiophene rings by means of Pd-catalyzed cross-coupling reactions, which lead to monomers 1 and 2. Copolymers P1 and P2 obtained by means of anodic polymerization have been characterized by spectroscopic and electrochemical methods. Electrochromism was observed for both polymers. The experimental data supported by density functional theory modeling explain the influence of alkyl chain substitution on the properties of the investigated copolymers.
    ChemPlusChem 01/2015;
  • [Show abstract] [Hide abstract]
    ABSTRACT: Halogenated dodecaborates, and especially dodecaiodododecaborate(2−), are found to trigger effectively the release of the contents of phospholipid liposomes, including liposomes containing distearoylphosphatidylcholine and cholesterol, which are used clinically in cancer therapy. The basis of the release is studied through differential scanning calorimetry, cryo-transmission electron microscopy, and atomic force microscopy. Upon administration at high concentrations, drastic morphological changes are induced by the dodecaborates. Their possible use in triggered release is suggested.
    ChemPlusChem 01/2015;
  • [Show abstract] [Hide abstract]
    ABSTRACT: Diverse titanium dioxide (TiO2) nanostructures have attracted considerable attention owing to their broad applications in photocatalytic and photoelectrochemical fields. Herein, TiO2 hollow single nanocrystals are reported for the first time by using TiO2 nanopowders as the raw material and hydrofluoric acid as a capping and etching agent through a simple hydrothermal treatment. The influence of experimental parameters such as the concentration of HF, the amount of TiO2 nanoparticles, the reaction time, and temperature was investigated systematically. The obtained hollow single nanocrystals exhibited enhanced photoelectrochemical and photocatalytic performances attributed to their good crystallinity, suppressed charge recombination, and increased active sites. The current study will provide new insights into the nanostructured engineering of anatase TiO2 as well as opportunities for the controllable synthesis of hollow single nanocrystals.
    ChemPlusChem 01/2015;
  • [Show abstract] [Hide abstract]
    ABSTRACT: New task-specific ionic liquids, hydroxy-functionalized 1-methyl-3-alkylimidazolium hydroxides, were used as catalysts in the transesterification of rapeseed oil with methanol. In comparison to the well-described 1-methyl-3-butylimidazolium hydroxide [bmim]OH, the new ionic liquids show unexpectedly high catalytic activity. In case of the ionic liquid [glymim]OH, which is structurally similar to glycerol, the conversion of rapeseed oil was nearly 100 %.
    ChemPlusChem 01/2015;
  • [Show abstract] [Hide abstract]
    ABSTRACT: Aromatic organic molecules serve as optoelectronic materials owing to their intrinsic optical and electronic properties. Herein, self-assembled lamellar nanostructures as photoconductor hybrids, which are obtained from naphthalene-2-methoxycarbonyl (Nmoc)-capped peptide amphiphiles, are described. Hybrid nanostructures are constructed in a controlled manner by an electrochemical deposition technique in combination with the inorganic Zn(OH)2 phase. Inorganic Zn(OH)2 layers turn into semiconductor ZnO layers upon annealing at 150 °C and lamellar nanostructures are formed in a periodic manner. Synergistic effects of hydrogen bonding and π–π stacking interactions of aromatic peptide amphiphiles are the driving force for the formation of self-assembled lamellar nanostructures. Morphological, structural, and optical studies of such lamellar hybrid nanostructures are reported. Photoconduction of these hybrid nanostructures is also examined in detail.
    ChemPlusChem 01/2015;
  • [Show abstract] [Hide abstract]
    ABSTRACT: A non-enzymatic amperometric glucose sensor that can be renewed by light irradiation is described. It is composed of Ni/NiTiO3/TiO2 nanotube arrays (NTAs) prepared by a simple hydrothermal treatment of as-anodized TiO2 NTAs in a nickel acetate solution followed by annealing under H2/Ar. The Ni/NiTiO3/TiO2 NTAs exhibit excellent electrocatalytic activity towards glucose oxidation in a 1.0 M NaOH supporting solution at a low applied potential of 0.4 V (vs. Ag/AgCl) with a high sensitivity of 456.4 μA cm−2 mM−1 and a low detection limit of 0.7 μM (S/N=3). The excellent electrochemical biosensing properties for glucose detection can be attributed to the orderly vertical alignment, large accessible surface, high conductivity, and electroactive NiII/NiIII redox couple. Meanwhile, owing to their high photocatalytic activity, Ni/NiTiO3/TiO2 NTAs can readily decompose the organic fouling species generated on the electrode surface during glucose detection under light irradiation so that the original sensitivity and selectivity can be restored. The Ni/NiTiO3/TiO2 NTAs electrode provides a promising renewable platform enabling long-term glucose monitoring with high sensitivity and selectivity.
    ChemPlusChem 01/2015;
  • [Show abstract] [Hide abstract]
    ABSTRACT: A novel radical monomer containing triphenylamine and the 2,2,6,6-tetramethylpiperidinyl-N-oxy (TEMPO) radical has been synthesized. The corresponding linear homopolymer of 4-carboxy-N,N-diphenylaniline-2,2,6,6-tetramethylpiperidin-1-yloxy (PTPA-TEMPO) was then prepared by chemical oxidative polymerization. The chemical structure and electrochemical properties of the prepared polymers were characterized by Fourier transform infrared spectroscopy, ultraviolet–visible spectroscopy, scanning electron microscopy, cyclic voltammetry, and galvanostatic charge–discharge testing by the simulated lithium-ion half-cell method. The results demonstrated that the as-synthesized functional polymers exhibited an initial discharge capacity of up to 140 mAh g−1 with two well-defined plateaus at the potential of 3.8 and 2.7 V versus Li/Li+. Furthermore, the PTPA-TEMPO electrode showed superior cycling and rate performances. The improved electrochemical performances were attributed to the construction of the novel linear radical molecular structure with PTPA as the conductive polymer backbone, which improved the long-range charge-carrier transportation and facilitated the Li+-ion insertion–extraction process in the aggregated polymer bulk during the charge–discharge process.
    ChemPlusChem 01/2015;
  • [Show abstract] [Hide abstract]
    ABSTRACT: Novel layered organic–inorganic materials functionalized with amino groups have been synthesized by using a two-dimensional zeolitic precursor, IPC-1P, prepared by a top-down approach from zeolite UTL. The formation of porous materials containing silsesquioxane linkers covalently bonded to zeolite layers in the interlayer space was confirmed by a variety of characterization techniques (N2 sorption, XRD, TEM). The textural properties and catalytic behavior of functionalized hybrid materials synthesized by direct pillaring of IPC-1P or by grafting of (3-aminopropyl)silyl groups to the IPC-1P precursor preliminarily pillared with tetraethoxysilane (TEOS) were compared. The use of a mixture of aminosilsesquioxanes and TEOS for pillaring of IPC-1P led to the formation of functionalized materials, which are characterized by excellent textural properties (SBET=154–435 m2 g−1, Vtotal=0.336–0.630 cm3 g−1) and provide a 100 % yield of target benzylidenemalononitrile in the Knoevenagel condensation of benzaldehyde and malononitrile.
    ChemPlusChem 01/2015;
  • [Show abstract] [Hide abstract]
    ABSTRACT: The role of pH in the formation of metal–organic frameworks (MOFs) has been studied on magnesium-based carboxylate framework systems [Mg(Pdc)(H2O)3]n (1) and [Mg(Pdc)(H2O)]n (2) (Pdc=pyridine-2,3-dicarboxylate). The investigation reveals the formation of two different compounds of one- or three-dimensions starting from the same reaction mixture that differs only in pH. Isolated compounds have been characterized by IR and elemental analysis; both compounds were also successfully characterized by single-crystal X-ray diffraction. This study shows that the gradual increase in pH helps to construct a higher-dimensional network. Catalytic activity of compounds 1 and 2 was tested for the Claisen–Schmidt reaction. Compound 2 was successfully dehydrated to produce a coordinately unsaturated compound 2 a, which shows higher catalytic activity than 1 or 2 in heterogeneous medium.
    ChemPlusChem 01/2015;
  • [Show abstract] [Hide abstract]
    ABSTRACT: The NH2-terminated mesogenic group 4-(6-amine-hexyloxy)-4*-cyan-biphenyl is chemically grafted onto the carboxylic groups of graphene oxide (GO) through an amidation reaction. The resultant mesogenic-group-modified GO sheets (GO-LC) are redispersed easily in common organic solvents, facilitating the structure characterization and device fabrication by solution processing. Broad-band reflectors are obtained by doping different contents of GO-LC nanosheets into chiral nematic liquid crystalline (N*-LCs) media with a photopolymerization process. The experimental results show that both the bandwidth of the reflection spectrum and the location of the reflection band of the GO-LC-doped composite films are better than those of the N*-LCs sample without GO-LC doping. The effects of polymerization temperature and amount of GO-LC dopant on the broad-band reflection of the N*-LC composite films are investigated.
    ChemPlusChem 01/2015;
  • [Show abstract] [Hide abstract]
    ABSTRACT: Herein we report the application of ZIF-90, which is a highly porous zeolitic imidazolate framework, as a novel catalyst for the cycloaddition of propylene oxide (PO) with CO2 in the absence of co-catalysts and solvents under moderate reaction conditions. The effects of various reaction parameters were investigated. The activity of ZIF-90 was compared with that of various metal–organic-framework (MOF)-based catalysts for the cycloaddition of PO with CO2. Density functional theory calculations elucidated the role of ZIF-90 in creating a favorable environment for the PO–CO2 cycloaddition reaction. A reaction mechanism for the ZIF-90-catalyzed PO–CO2 cycloaddition on the basis of DFT calculations is proposed and the regeneration of ZIF-90 is discussed.
    ChemPlusChem 01/2015;
  • [Show abstract] [Hide abstract]
    ABSTRACT: Imine-linked pyridine-coupled (ILPC) receptors have been synthesised and characterised. The absorption and fluorescence properties of these receptors have been explored through a combination of experimental and theoretical studies. The ILPC receptors are processed into organic nanoparticles (ONPs) and then decorated with gold nanoparticles (AuNPs) for the selective recognition of iodide. The selective recognition behaviour is authenticated with the changes in fluorescence spectra, low detection limit (1.4 nM) and no interference in aqueous systems. The present investigation represents the first example of nanomolar detection of iodide in aqueous medium using organic–inorganic hybrid nanoparticles (ONPs–AuNPs). The probe has been utilised successfully for the detection of iodide content in urine samples.
    ChemPlusChem 01/2015;
  • ChemPlusChem 01/2015; 80(1).
  • ChemPlusChem 01/2015; 80(1).
  • [Show abstract] [Hide abstract]
    ABSTRACT: Porpholactones and their derivatives have attracted increasing attention for their promising application as photosensitizers. Reduction of the β-lactone moiety in porpholactone to β-hemiacetal, named porpholactol, allows the synthesis of chlorin-type photosensitizers with enhanced near-infrared absorption as well as β functionalization of water-soluble conjugates. By employing β-hydrophilic conjugates terminated by different ionic groups, such as neutral (ZnL1), anionic (ZnL2), zwitterionic (ZnL3), and cationic (ZnL4–6) groups, a series of photosensitizers (ZnL1–6) were synthesized and characterized, and their photophysical properties were studied, including magnetic circular dichroism measurement. The terminal ionic groups on β conjugates influence significantly the cellular uptake of ZnL1–6 in the order ZnL4–6 (positive charge)>ZnL1–3 (negative charge or neutral). Importantly, the photocytotoxicity of ZnL1–6 against cancer cells showed IC50 values down to the sub-micromolar range and exhibited the same trend as their cellular uptake, clearly revealing the relationship of β-ionic conjugates, cellular uptake, and intracellular photodynamic therapy (PDT) activity. Furthermore, using ZnL4 as an example, mechanistic studies, such as cell imaging experiments and Western blot analysis for the PDT process, indicate that ZnL4 exerts photodynamic activity through apoptosis, which is highly associated with lysosome disruption, mitochondria depolarization, and nuclei condensation.
    ChemPlusChem 12/2014;