Interface focus: a theme supplement of Journal of the Royal Society interface Impact Factor & Information

Publisher: Royal Society, The

Current impact factor: 2.63

Impact Factor Rankings

2015 Impact Factor Available summer 2016
2014 Impact Factor 2.63
2013 Impact Factor 3.124
2012 Impact Factor 2.206
2011 Impact Factor

Impact factor over time

Impact factor

Additional details

5-year impact 3.28
Cited half-life 2.70
Immediacy index 1.57
Eigenfactor 0.00
Article influence 1.30
ISSN 2042-8901

Publisher details

Royal Society, The

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    • Author's pre-print on free public servers
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    • Author's post-print on institutional repository or not-for-profit open access repository after 12 months embargo
    • Publisher's version/PDF cannot be used
    • Published source must be acknowledged with citation close to title of article
    • Must link to publisher version close to title of article
    • If funding agency rules apply, authors may post articles in PubMed Central 12 months after publication
    • Eligible UK authors may deposit in Open Depot (after 12 months)
    • Publisher last contacted on 21/04/2015
  • Classification

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: Abstract. Nanomedicine is a game-changing method to directly deliver drug molecules into diseased area. One of the most promising way among these is the targeted delivery of drugs and imaging agents by using drug carriers-based platforms. Such drug delivery systems can now be made from a wide range of different materials, in a number of different shapes, coated with an array of different organic molecules (including ligands), all leading to enhancements in delivery efficacy and specificity, comparing with existing delivery method. Emerging integrated multiscale experiments, models and simulations opened the door for endless medical applications. The current bottleneck in design of the drug-carrying particles is lack of knowledge about their dispersion in the microvasculature and subsequent internalization by diseased cells. We will show how drug carriers disperse in the microvessel through multiscale modeling technique. The immersed molecular finite element method (IMFEM) is adopted to simulate the whole blood including blood plasma, red blood cells and nanoparticles. With a novel dissipative particle dynamics method, the endocytosis of nanoparticles can be Cell and Nanoparticle Transport understood in detail. Using this multiscale modeling method, we elucidate how the size, shape and surface functionality of nanoparticles will affect their dispersion in the microvasculature and subsequent internalization by tumor cells.
    Interface focus: a theme supplement of Journal of the Royal Society interface 03/2016;
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    ABSTRACT: We describe a working mechanical device that embodies the theoretical computing machine of Alan Turing, and as such is a universal programmable computer. The device operates on three-dimensional building blocks by applying mechanical analogues of polymer elongation, cleavage and ligation, movement along a polymer, and control by molecular recognition unleashing allosteric conformational changes. Logically, the device is not more complicated than biomolecular machines of the living cell, and all its operations are part of the standard repertoire of these machines; hence, a biomolecular embodiment of the device is not infeasible. If implemented, such a biomolecular device may operate in vivo, interacting with its biochemical environment in a program-controlled manner. In particular, it may 'compute' synthetic biopolymers and release them into its environment in response to input from the environment, a capability that may have broad pharmaceutical and biological applications.
    Interface focus: a theme supplement of Journal of the Royal Society interface 08/2012; 2(4):497-503. DOI:10.1098/rsfs.2011.0118
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    ABSTRACT: Pattern formation in development is a complex process which involves spatially distributed signals called morphogens that influence gene expression and thus the phenotypic identity of cells. Usually different cell types are spatially segregated, and the boundary between them may be determined by a threshold value of some state variable. The question arises as to how sensitive the location of such a boundary is to variations in properties, such as parameter values, that characterize the system. Here, we analyse both deterministic and stochastic reaction-diffusion models of pattern formation with a view towards understanding how the signalling scheme used for patterning affects the variability of boundary determination between cell types in a developing tissue.
    Interface focus: a theme supplement of Journal of the Royal Society interface 08/2012; 2(4):465-86. DOI:10.1098/rsfs.2011.0116
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    ABSTRACT: Recent advances in the spectroscopy of biomolecules have highlighted the possibility of quantum coherence playing an active role in biological energy transport. The revelation that quantum coherence can survive in the hot and wet environment of biology has generated a lively debate across both the physics and biology communities. In particular, it remains unclear to what extent non-trivial quantum effects are used in biology and what advantage, if any, they afford. We propose an analogue quantum simulator, based on currently available techniques in ultra-cold atom physics, to study a model of energy and electron transport based on the Holstein Hamiltonian. By simulating the salient aspects of a biological system in a tunable laboratory set-up, we hope to gain insight into the validity of several theoretical models of biological quantum transport in a variety of relevant parameter regimes.
    Interface focus: a theme supplement of Journal of the Royal Society interface 08/2012; 2(4):522-8. DOI:10.1098/rsfs.2011.0109
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    ABSTRACT: The paper reviews two computing models by DNA self-assembly whose proof of principal have recently been experimentally confirmed. The first model incorporates DNA nano-devices and triple crossover DNA molecules to algorithmically arrange non-DNA species. This is achieved by simulating a finite-state automaton with output where golden nanoparticles are assembled to read-out the result. In the second model, a complex DNA molecule representing a graph emerges as a solution of a computational problem. This supports the idea that in molecular self-assembly computing, it may be necessary to develop the notion of shape processing besides the classical approach through symbol processing.
    Interface focus: a theme supplement of Journal of the Royal Society interface 08/2012; 2(4):504-11. DOI:10.1098/rsfs.2011.0117
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    ABSTRACT: The application of mathematical models in biology and medicine has a long history. From the sparse number of papers in the first half of the twentieth century with a few scientists working in the field it has become vast with thousands of active researchers. We give a brief, and far from definitive history, of how some parts of the field have developed and how the type of research has changed. We describe in more detail just two examples of specific models which are directly related to real biological problems, namely animal coat patterns and the growth and image enhancement of glioblastoma brain tumours.
    Interface focus: a theme supplement of Journal of the Royal Society interface 08/2012; 2(4):397-406. DOI:10.1098/rsfs.2011.0102