African journal of pharmacy and pharmacology Impact Factor & Information

Publisher: Academic Journals

Journal description

Current impact factor: 0.84

Impact Factor Rankings

2015 Impact Factor Available summer 2015
2011 Impact Factor 0.839
2010 Impact Factor 0.5
2009 Impact Factor 0.667

Impact factor over time

Impact factor

Additional details

5-year impact 0.88
Cited half-life 2.00
Immediacy index 0.20
Eigenfactor 0.00
Article influence 0.09
ISSN 1996-0816

Publisher details

Academic Journals

  • Pre-print
    • Author can archive a pre-print version
  • Post-print
    • Author can archive a post-print version
  • Conditions
    • Creative Commons Attribution License
    • Eligible UK authors may deposit in OpenDepot
    • Publisher's version/PDF may be used
    • Published source must be acknowledged
    • All titles are open access journals
    • Publisher last contacted on 11/10/2014
  • Classification
    ​ green

Publications in this journal

  • African journal of pharmacy and pharmacology 03/2015;
  • [Show abstract] [Hide abstract]
    ABSTRACT: Protium heptaphyllum (PH) is rich in essential oil, has anti-inflammatory properties and has no toxic potential. However, data is unavailable about its antiseptic effect against bacteria that cause caries. This study aimed to evaluate the antiseptic effect of the toothbrush rinse of essential oil of PH as well as its chemical stability. The toothbrush rinse was prepared with 1% essential oil of PH. The minimum inhibitory concentration (MIC) of the essential oil and toothbrush rinse were evaluated against Streptococcus mutans (ATCC 25175™). The ex vivo study was double-blinded and randomised; the children were divided into three groups, each participating in a crossover design where all solutions (water, toothbrush rinse (1%) and chlorhexidine (0.12%) were used in all stages by different groups of children. The chemical composition of the essential oil and toothbrush rinse were analysed by gas chromatography coupled to mass spectrometry. The stability was evaluated at three time points. The essential oil and toothbrush rinse exhibited antimicrobial activity against S. mutans, MIC = 0.125 and 2.4 µg/ml. The toothbrush rinse showed the same effect as chlorhexidine on disinfecting the toothbrushes contaminated with mutans streptococci (pH = 57.3 ± 5.3%; chlorhexidine 55.5 ± 13.3%; water 39.4 ± 5.8%; p > 0.05). Chromatographic analysis showed that the essential oil contained monoterpenes as a major component, and the toothbrush rinse possessed the same constituents as the pure essential oil, except for α-terpineol. Storage did not cause chemical degradation of the toothbrush rinse, but decreased the concentration of the chemical constituents. The toothbrush rinse of essential oil of P. heptaphyllum showed antiseptic properties and exhibited antimicrobial activity against mutans streptococci. Key words: Mutans streptococci, Protium heptaphyllum, antimicrobial, monoterpenes, chemical composition, contamination of toothbrushes.
    African journal of pharmacy and pharmacology 02/2015; 9(6):173-181.