Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment Journal Impact Factor & Information

Publisher: Taylor & Francis

Current impact factor: 1.80

Impact Factor Rankings

2015 Impact Factor Available summer 2016
2014 Impact Factor 1.802
2013 Impact Factor 2.341
2012 Impact Factor 2.22
2011 Impact Factor 1.765
2010 Impact Factor 2.23

Impact factor over time

Impact factor

Additional details

5-year impact 2.20
Cited half-life 7.40
Immediacy index 0.31
Eigenfactor 0.01
Article influence 0.52
ISSN 1944-0057

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Taylor & Francis

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    • STM: Science, Technology and Medicine
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Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: The Evidence Investigator™ system (Randox, UK) is a biochip and semi- automated system. The microarray kit II (AM II) is capable of detecting several compounds belonging to different families of antibiotics: quinolones, ceftiofur, thiamphenicol, streptomycin, tylosin, and tetracyclines. The performance of this innovative system was evaluated for the detection of antibiotic residues in new matrices, in muscle of different animal species and in aquaculture products. The method was validated according to the European decision EC/2002/657 and to the European guideline for the validation of screening methods, which represents a complete initial validation. The false positive rate was equal to 0% in muscle and in aquaculture products. The detection capabilities CCβ for 12 validated antibiotics (enrofloxacin, difloxacin, ceftiofur, Desfuroyl Ceftiofur Cysteine Disulfide, thiamphenicol, florfenicol, tylosin, tilmicosin, streptomycin, dihydrostreptomycin, tetracycline, doxycycline) were all lower than the respective MRLs in muscle from different animal origins (bovine, ovine, porcine, poultry). No cross-reactions were observed with other antibiotics neither of the 6 detected families nor with other families of antibiotics. The AM II kit could be applied to aquaculture products but with higher detection capabilities from those in muscle. The detection capabilities CCβ in aquaculture products were respectively at ¼, 1/10 and ½ of the respective MRL in aquaculture products for enrofloxacin, tylosin and oxytetracycline. The performance of the AM II kit have been compared with other screening methods and with the performance characteristics previously determined in honey.
    Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment 11/2015; DOI:10.1080/19440049.2015.1125529
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    ABSTRACT: Nitrite intake from consumption of cured meat and tap water was estimated for Finnish children of 1, 3 and 6 years as well as Finnish adults of 25 to 74 years. Nitrite content in the foods was measured by capillary electrophoresis, and was used together with individual food consumption data from FINDIET 2007 and DIPP studies in stochastic exposure assessment by Monte Carlo Risk Assessment program. Nitrite intake from additive sources and tap water was assessed, and more than every tenth child between the ages 3 and 6 was estimated to have nitrite intake exceeding the ADI of nitrite. The high exposure levels were caused by frequent consumption of large portions of sausages, up to 350 g/day or 750 g in 3 days, among the children. Median nitrite intake from cured meat was 0.016, 0.040, 0.033 and 0.005 mg/kg body weight/day for children of 1, 3 and 6 years and adults, respectively. Bayesian estimation was employed to determine safe consumption levels of sausages and cold cuts for children, and these results gave rise to new national food consumption advice.
    Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment 11/2015; DOI:10.1080/19440049.2015.1117145
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    ABSTRACT: In the present study, a new, low-cost, micellar sensitive and selective spectrophotometric method was developed for the determination of inorganic arsenic species in beverage samples. Vortex-assisted cloud point extraction (VA-CPE) was used for the efficient pre-concentration of As(V) in the selected samples. The method is based on selective and sensitive ion-pairing of As(V) with acridine red (ARH(+)) in the presence of pyrogallol and sequential extraction into the micellar phase of Triton X-45 at pH 6.0. Under the optimized conditions, the calibration curve was highly linear in the range of 0.8-280 µg L(-1) for As(V). The limits of detection and quantification of the method were found to be 0.25 and 0.83 µg L(-1), respectively. The method was successfully applied to the determination of trace arsenic in the pre-treated and digested samples under microwave and ultrasonic power. As(V) and total As levels in the samples were spectrophotometrically determined after pre-concentration with VA-CPE at 494 nm before and after oxidation with acidic KMnO4. The As(III) levels were calculated from the difference between As(V) and total As levels. The accuracy of the method was demonstrated by analysis of two certified reference materials (CRMs) where the measured values for As were statistically within the 95 % confidence limit for the certified values.
    Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment 11/2015; DOI:10.1080/19440049.2015.1118561
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    ABSTRACT: Mitigation strategies aimed at an intervention in the reaction pathways for furan formation (e.g. by adjusting precursor concentrations) might offer an additional route for furan reduction in sterilizedsterilised, vegetable-based foods, without adverse effects on other food safety or quality attributes. As a first step towards product re-formulation, the aim of the present study was to determine the relative importance and interactions of possible furan precursors in these types of foods. Based on an I-optimal experimental design, potato purée (naturally low in furan precursors) was spiked with known amounts of sugars, ascorbic acid, olive oil and β-carotene, and subjected to a thermal sterilizationsterilisation. Significant correlations were observed between furan concentrations after thermal treatment and starting concentrations of ascorbic acid and monosaccharides (i.e., fructose and glucose). Ascorbic acid had a clear furan reducing effect as an antioxidant, by protecting (polyunsaturated) fatty acids against oxidative degradation. Fructose and glucose were the main precursors, which can most probably be attributed to their high, but realistic concentrations in the product. The contributions of fatty acids and β-carotene were strongly dependent on redox interactions with other food constituents. In the same potato purées, only low concentrations (0-2 ng/g purée) of 2-methylfuran were detected, indicating that the direct importance of the spiked food constituents as a precursor for methylfuran formation was rather small. Based on the results of this study, reducing the amount of monosaccharides or adjusting the redox conditions of the matrix are suggested as two possible approaches for furan mitigation on the product side.
    Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment 11/2015; DOI:10.1080/19440049.2015.1124293
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    ABSTRACT: The distribution of fumonisins in the corn milling process and in corn-based products, as well as daily intake estimates for the Brazilian population were evaluated. Among corn fractions samples, corn meal had the highest mean concentration of FB1 (1305 µg kg(-1)) and FB2 (651 µg kg(-1)) and a distribution factor of 452% and 256% in relation to corn grain, respectively. On the other hand, the distribution factor of FB1 and FB2 in corn flour was found to be 144% and 88%, which demonstrates that fumonisins in this fraction were reduced compared to corn grain. As a result, almost half of the corn meal samples (47%) would be non-compliant with the future Brazilian regulation (2017) for fumonisins. However, corn-based products, such as cornflakes and popcorn, were in compliance with the regulation. The average probable daily intake and maximum probable daily intake of fumonisins estimated for the Santa Catarina state (Brazil) population were below the provisional maximum tolerable daily intake of 2 µg kg(-1) body weight day(-1) for all corn samples. Despite this, the adoption of practices to control the occurrence of fumonisins should be applied to the corn milling fractions that may contain a higher concentration of this toxin, such as corn meal, often used for animal feed in Brazil.
    Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment 11/2015; DOI:10.1080/19440049.2015.1124459
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    ABSTRACT: Bisphenol F (BPF) was found in mustard up to a concentration of around 8 mg kg(-1). Contamination of the raw products or caused by the packaging could be ruled out. Also the fact that only the 4,4'-isomer of BPF was detected spoke against a contamination from epoxy resin or other sources where technical BPF is used. Only mild mustard made of the seeds of Sinapis alba contained BPF. In all probability BPF is a reaction product from the breakdown of the glucosinolate glucosinalbin with 4-hydroxybenzyl alcohol as an important intermediate. Hot mustard which was made only from brown mustard seeds (Brassica juncea) or black mustard seeds (Brassica nigra) contained no BPF. BPF is structurally very similar to bisphenol A and has a similar weak estrogenic activity. The consumption of a portion of 20 g of mustard can lead to an intake of 100 to 200 µg of BPF. According to a preliminary risk assessment, the risk of BPF in mustard for the health of consumers is considered as low, but available toxicological data are insufficient for a conclusive evaluation. It is a new and surprising finding, that BPF is a natural food ingredient and that this is the main uptake route. This insight sheds new light on the risk linked to the family of bisphenols.
    Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment 11/2015; DOI:10.1080/19440049.2015.1110623
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    ABSTRACT: Delvotest® T was evaluated for its capability at detecting residues of 27 antibiotics in raw cow's milk and in some dairy ingredients (skimmed and full cream milk powders). The kit was used as a screening tool for the qualitative determination of antibiotics from different families in one single test. Results delivered by such a method are expressed as "positive" or "negative" referred to the claimed screening target concentration (STC). Validation was conducted according to the European Community Reference Laboratories (CRLs) Residues guidelines 2010/01/20 and performed by two laboratories, one located in Europe and the other in Asia. Five criteria were evaluated including detection capability at STC, false positive (FP) rate, false negative (FN) rate, robustness and cross-reactivity using visual reading and Delvoscan®. STCs were set at/or below the corresponding maximum residue limit (MRL) as fixed by the European Regulation EC 37/2010. Four antibiotics (nafcillin, oxytetracycline, tetracycline and rifaximin) out of twenty seven had a false negative rate ranging from 1.7% to 4.9%, however still compliant with CRLs requirements. Globally, Delvotest® T can be recommended for the analysis of the surveyed antibiotics in raw cow's milk, skimmed and full cream milk powders. Additional compounds were tested such as sulfamethazine, spiramycin, and erythromycin, however detection at the corresponding MRL was not achievable and these compounds were removed from validation. Other drugs from the sulfonamide, aminoglycoside or macrolide families not detected by the test at the MRL were not evaluated in this study. Regarding the reliability of this rapid test to milk-based preparations, additional experiments should be performed on a larger range of compounds and samples to validate the Delvotest® T in such matrices.
    Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment 11/2015; DOI:10.1080/19440049.2015.1104731
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    ABSTRACT: This paper describes the operation of the European Union Reference Laboratory for feed additives (EURL) and its role in the authorisation procedure of feed additives in the EU. Feed additives are authorised according to Regulation (EC) 1831/2003, which introduced a completely revised authorisation procedure and also established the EURL. The Regulations authorising feed additives contain conditions of use such as legal limits of the feed additives, which require the availability of suitable method of analysis for official control purposes under real world conditions. It is the task of the EURL to evaluate the suitability of analytical methods as proposed by the industry for this purpose. Moreover, the paper shows that one of the major challenges is the huge variety of the methodology applied in feed additive analysis, thus requiring expertise in quite different analytical areas. In order to cope with this challenge the EURL is supported by a network of National Reference Laboratories (NRLs) and only the merged knowledge of all NRLs allows for a scientifically sound assessment of the analytical methods.
    Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment 11/2015; DOI:10.1080/19440049.2015.1116127
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    ABSTRACT: The effect of water activity (aw: 0.95, 0.98, 0.995), temperature (15, 25 and 30°C), incubation time (7, 14, 21 and 28 days) and their interactions on growth and moniliformin (MON), beauvericin (BEA), fusaproliferin (FUS) and fumonisin B1 (FB1) production by two strains of Fusarium temperatum isolated from Argentinean maize were determined in vitro on sterile layers of maize grains. The results showed that there was a wide range of conditions for growth and mycotoxins production by F. temperatum. Both strains were found to grow faster with increasing aw and at 30°C. In relation to mycotoxin production, the two strains produced more FUS than the other mycotoxins regardless of aw or temperature evaluated (max: 50,000 μg g(-1)). For FUS, MON and BEA, the maximum levels were observed at 0.98aw and 30°C (50,000 μg g(-1), 5000 μg g(-1)and 2000 μg g(-1)respectively). The lowest levels for these three mycotoxins were detected at 15°C and 0.95aw (1700 μg g(-1)and 100 μg g(-1) for FUS and MON), and at 0.98aw (400 μg g(-1) for BEA). The maximum levels of FB1 were produced at 15°C and 0.98aw (1000 μg g(-1)). At all aw and temperatures combinations evaluated, there was an increase in toxin concentrations with time incubation. The maximum levels were detected at 21 days. Statistical analyses of aw, temperature, incubation time and the two- and three-way interactions between them, showed significant effects on mycotoxins production by F. temperatum. For its versatility on growth and mycotoxin production, F. temperatum represents a toxicological risk for maize in the field and also during grain storage.
    Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment 11/2015; DOI:10.1080/19440049.2015.1107917
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    ABSTRACT: The aims of the current cross-sectional study were i) to assess the intake of aspartame, cyclamate, acesulfame-k, neohesperidine dihydrochalcone, sucralose, saccharin, steviolglycosides and neotame among children with Type 1 Diabetes mellitus (T1D); ii) to compare the obtained intakes with the respective Acceptable Daily Intake (ADI) values and iii) to conduct a scenario analysis to obtain practical guidelines for a safe consumption of non-nutritive sweeteners (NNS) among children with T1D. Type 1 diabetic patients of the Paediatrics Department of the University Hospitals Leuven were invited to complete a food frequency questionnaire, designed to assess NNS intake using a Tier 2 and Tier 3 exposure assessment approach. A scenario analysis was conducted by reducing the P95 consumption of the most contributing food categories in order to reach a total sweetener intake lower or equal to the ADI. Estimated total intakes higher than ADIs were only found for the P95 consumers-only of acesulfame-k, cyclamate and steviolglycosides (Tier 2 and Tier 3 approach). Scenario analysis created dietary guidelines for each age category for diet soda, bread spreads and dairy drinks. There is little chance for T1D children to exceed the ADI of the different NNS, however diabetes educators and dieticians needs to pay attention regarding the use of NNS.
    Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment 11/2015; DOI:10.1080/19440049.2015.1112039
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    ABSTRACT: This paper reports the effects of rinsing rice and cooking it in variable amounts of water on total arsenic, inorganic arsenic, iron, cadmium, manganese, folate, thiamin and niacin in the cooked grain. We prepared multiple rice varietals both rinsed and unrinsed and with varying amounts of cooking water. Rinsing rice before cooking has a minimal effect on the arsenic (As) content of the cooked grain, but washes enriched iron, folate, thiamin and niacin from polished and parboiled rice. Cooking rice in excess water efficiently reduces the amount of As in the cooked grain. Excess water cooking reduces average inorganic As by 40% from long grain polished, 60% from parboiled and 50% from brown rice. Iron, folate, niacin and thiamin are reduced by 50-70% for enriched polished and parboiled rice, but significantly less so for brown rice, which is not enriched.
    Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment 11/2015; DOI:10.1080/19440049.2015.1103906
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    ABSTRACT: Food is likely to be one of the major pathways through which people are exposed to endocrine disrupting chemicals. With the exception of residual effects, there are concerns that a number of naturally occurring and synthetic chemicals exert adverse effects upon endocrine systems in wildlife and humans. The current study reports selected pesticide concentrations and the total estrogenic activity of fruit and vegetables using the recombinant Yeast Oestrogen Screen (YES) and T47D-KBluc reporter gene assays. A total of 53 food samples (27 fruit and 26 vegetables) from Johannesburg and Tshwane Fresh Produce Markets (in South Africa) were analysed. Of these 17 contained one to three different pesticide residues with concentrations ranging between 0.01 and 0.68 mg/kg, whereas in the rest of the samples no residues were detected. All pesticides detected except in one sample were below the maximum residue level (MRL), but others were unauthorised for use in specified fruit and vegetables. Estrogenic activity was detected in 26.4% (14 samples) of the samples tested, and the estradiol equivalents ranged from 0.007 to 2 pg/g. Although the estrogenic activity was low, it may contribute to adverse health effects. Continuous monitoring for pesticides in fruit and vegetables is important, in view of the unauthorised pesticides detected in produce from South Africa and the endocrine disrupting chemical activity found.
    Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment 10/2015; DOI:10.1080/19440049.2015.1103905
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    ABSTRACT: The impact of meat additives on the concentration of biogenic amines and the quality of meat was studied. Fresh white and red meat samples were fortified with the following food additives: citric and lactic acids, disodium diphosphate, sodium nitrite, sodium metabisulphite, potassium sorbate, sodium chloride, ascorbic acid, α-tocopherol, propyl 3,4,5-trihydroxybenzoate (propyl gallate) and butylated hydroxyanisole. The content of spermine, spermidine, putrescine, cadaverine, histamine, tyramine, tryptamine and 2-phenylethylamine was determined by capillary isotachophoretic methods in meat samples (fresh and fortified) during four days of storage at 4°C. The results were applied to estimate the impact of the tested additives on the formation of biogenic amines in white and red meat. For all tested meats, sodium nitrite, sodium chloride and disodium diphosphate showed the best inhibition. However, cadaverine and putrescine were characterised by the biggest changes in concentration during storage time of all the additives. Based on the presented data for the content of biogenic amines in meat samples analysed as a function of storage time and additives, we suggest that cadaverine and putrescine have a significant impact on meat quality.
    Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment 10/2015; DOI:10.1080/19440049.2015.1111525
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    ABSTRACT: Under current EU legislation the use of anabolic steroids in food-producing livestock is banned because of their long-term adverse effects to human health. We examined the expression profile of the immunohistochemical marker Progesterone Receptor in veal calves sex accessory glands following experimental administration of anabolic compounds. The aim was to confirm the accuracy of the immunohistochemical approach in the detection of the over expression of the Progesterone Receptor induced by the administration of sexual steroids at low levels (17β-estradiol and nandrolone alone or in combination). Two hundred and seventeen male veal calves were randomly divided into 4 groups: group A (104 calves) treated with 17β-estradiol (5 mg/head; 4 weekly injections); group B (20 calves) treated with nandrolone (50 mg/head; 4 weekly injections); group C (20 calves) treated with the association of the two steroids (5 mg estradiol + 50 mg nandrolone; 4 weekly injections); group K (73 calves) kept as control. All the sexual accessory glands were collected at the slaughterhouse (15 days after the last administration) and subjected to immunohistochemical staining with anti-Progesterone Receptor antibody. All the calves treated with 17β-estradiol alone or in association with nandrolone (Group A and C) showed strong positivity, while nandrolone-treated calves and controls (Group B and K) gave negative results to the immunohistochemical investigation. The statistical analysis showed that the Progesterone Receptor is a significant predictor of 17β-estradiol treatment alone or in association with nandrolone (p < 0.001): the immunohistochemical study resulted in 100% sensitivity (CI 95%: 97,1-100) and specificity (CI 95%: 95,1-100) for prostate and 99% sensitivity (CI 95%: 95,6-100) and 100% specificity (CI 95%: 95,1-100) for bulbo-urethral glands. Our data confirm that this innovative biological approach offers a reliable tool to enhance the efficacy of the histological test to detect illegal treatments with estrogens, alone or in association with androgens.
    Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment 10/2015; DOI:10.1080/19440049.2015.1107918