ACS Nano

Publisher: American Chemical Society, American Chemical Society

Current impact factor: 12.88

Impact Factor Rankings

2015 Impact Factor Available summer 2016
2014 Impact Factor 12.881
2013 Impact Factor 12.033
2012 Impact Factor 12.062
2011 Impact Factor 10.774
2010 Impact Factor 9.855
2009 Impact Factor 7.493
2008 Impact Factor 5.472

Impact factor over time

Impact factor

Additional details

5-year impact 14.41
Cited half-life 3.40
Immediacy index 2.22
Eigenfactor 0.31
Article influence 3.98
Other titles ACS nano (Online), ACS nano, American Chemical Society nano
ISSN 1936-086X
OCLC 85374429
Material type Document, Periodical, Internet resource
Document type Internet Resource, Computer File, Journal / Magazine / Newspaper

Publisher details

American Chemical Society

  • Pre-print
    • Author cannot archive a pre-print version
  • Restrictions
    • Must obtain written permission from Editor
    • Must not violate ACS ethical Guidelines
  • Post-print
    • Author cannot archive a post-print version
  • Restrictions
    • If mandated by funding agency or employer/ institution
    • If mandated to deposit before 12 months, must obtain waiver from Institution/Funding agency or use AuthorChoice
    • 12 months embargo
  • Conditions
    • On author's personal website, pre-print servers, institutional website, institutional repositories or subject repositories
    • Non-Commercial
    • Must be accompanied by set statement (see policy)
    • Must link to publisher version
    • Publisher's version/PDF cannot be used
    • If mandated sooner than 12 months, must obtain waiver from Editors or use AuthorChoice
    • Reviewed on 07/08/2014
  • Classification

Publications in this journal

  • Harry Mönig · Diego R Hermoso · Oscar Díaz Arado · Milica Todorović · Alexander Timmer · Simon Schüer · Gernot Langewisch · Ruben Perez · Harald Fuchs ·
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    ABSTRACT: In scanning probe microscopy, the imaging characteristics in the various interaction channels crucially depend on the chemical termination of the probe tip. Here we analyze the contrast signatures of an oxygen-terminated copper tip with a tetrahedral configuration of the covalently bound terminal O atom. Supported by first-principles calculations we show how this tip termination can be identified by contrast analysis in non-contact atomic force- and scanning tunneling microscopy (NC-AFM, STM) on a partially oxidized Cu(110) surface. After controlled tip functionalization by soft indentations of only a few Ångstroms in an oxide nano-domain, we demonstrate that this tip allows imaging an organic molecule adsorbed on Cu(110) by constant height NC-AFM in the repulsive force regime, revealing its internal bond structure. In established tip functionalization approaches where e.g. CO or Xe is deliberately picked up from a surface, these probe particles are only weakly bound to the metallic tip leading to lateral deflections during scanning. Therefore, the contrast mechanism is subject to image distortions, artifacts, and related controversies. In contrast, our simulations for the O-terminated Cu tip show that lateral deflections of the terminating O atom are negligible. This allows a detailed discussion of the fundamental imaging mechanisms in high resolution NC-AFM experiments. With its structural rigidity, its chemically passivated state and a high electron density at the apex, we identify the main characteristics of the O-terminated Cu tip making it a highly attractive complementary probe for the characterization of organic nanostructures on surfaces.
    ACS Nano 11/2015; DOI:10.1021/acsnano.5b06513
  • Jing Yu · Yanmin Ju · Lingyun Zhao · Xin Chu · Wenlong Yang · Yonglu Tian · Fugeng Sheng · Lei Zhang · Jian Lin · Fei Liu · Yunhe Dong · Yanglong Hou ·
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    ABSTRACT: Stimuli-controlled drug delivery and release is of great significance in cancer therapy, endowing the stimuli-responsive drug carrier highly demanded. Herein, a multi-stimuli-controlled drug carrier was developed by coating bovine serum albumin on Fe5C2 nanoparticles (NPs). With a high loading of anticancer drug doxorubicin, the nanoplatform provides a burst drug release when exposed to near-infrared (NIR) light or acidic condition. In vitro experiment demonstrated a NIR-regulated cell inhibition which is ascribed from cellular uptake of the carrier and the combination of photothermal therapy and enhanced drug release. The carrier is also magnetic field responsive, which enable the target drug delivery under the guidance of magnetic field, and monitor the theranostic effect by magnetic resonance imaging. In vivo synergistic effect demonstrates that the magnetic-driven accumulation of NPs can induce a complete tumor inhibition without appreciable side effect to the treated mice by NIR irradiation, due to the combined photo-chemotherapy. Our results highlight the great potential of Fe5C2 NPs as a remote-controlled platform for photo-chemothermal cancer therapy.
    ACS Nano 11/2015; DOI:10.1021/acsnano.5b04706

  • ACS Nano 11/2015; 9(11):10533. DOI:10.1021/acsnano.5b07205

  • ACS Nano 11/2015; 118(19). DOI:10.1063/1.4935820
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    ABSTRACT: Synthetic nucleic acids offer rich potential to understand and engineer new cellular functions, yet an unresolved limitation in their production and usage are deleterious products, which limit design complexity and add cost. Herein, we employ a solid-state nanopore to differentiate molecules of a gene synthesis reaction into categories of correct and incorrect assemblies. This new method offers a solution that provides information on gene synthesis reactions in near-real time with higher complexity and lower costs. This advance can permit insights into gene synthesis reactions such as kinetics monitoring, real-time tuning, and optimization of factors that drive reaction-to-reaction variations as well as open venues between nanopore-sensing, synthetic biology, and DNA nanotechnology.
    ACS Nano 11/2015; DOI:10.1021/acsnano.5b05782
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    ABSTRACT: Surface-induced protein denaturation has important implications for the development of materials that are resistant and/or innocuous to biomolecules. Here, we studied the mechanism of lysozyme (T4L) unfolding on fused silica (FS) using single-molecule methods that provided direct insight into the cause of denaturation. Unfolding of T4L was monitored by Förster resonance energy transfer while simultaneously tracking the adsorption, diffusion, and desorption of individual molecules at the solid-solution interface. Results of high-throughput single-molecule analysis suggested that the unfolding of T4L on FS was mediated by surface diffusion and occurred on isolated nanoscale sites, which were relatively rare and distinct from the majority of the surface. These observations suggest that surface-mediated protein unfolding is a search process that is based on the exploration for denaturing sites by the protein. Ultimately, these findings have important implications for the design of protein-compatible surfaces.
    ACS Nano 11/2015; DOI:10.1021/acsnano.5b05787
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    ABSTRACT: Successful application of graphene is hampered by the lack of the cost-effective methods of its production. Here we demonstrate a method of mass production of graphene nanoplatelets (GNPs) by exfoliation of flake graphite in the tri-component system made by combination of ammonium persulfate ((NH4)2S2O8), concentrated sulfuric acid, and fuming sulfuric acid. The resulting GNPs are tens of microns in diameter, and 10 to 35 nm in thickness. When in the liquid phase of the tri-component media, graphite completely loses its interlayer registry. This provides a ~ 100% yield of GNPs from graphite in 3 to 4 h at room temperature or in 10 min at 120 °.
    ACS Nano 11/2015; DOI:10.1021/acsnano.5b06840
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    ABSTRACT: Oriented attachment (OA), a non-classical crystal growth mechanism, provides a powerful bottom-up approach to obtain ordered superstructures, which also emerge exciting charge transmission characteristic. However, there is little work observably pronouncing the achievement of 3D OA growth of crystallites with large size (e.g. submicron crystals). Here, we report that SnO2 3D ordered superstructures can be synthesized by means of a self-limited assembly assisted by OA in a designed high-pressure solvothermal system. The size of primary building blocks is 200~250 nm, which is significantly larger than previous results (normally < 10 nm). High pressure plays the key role in the formation of 3D configuration and fusion of adjacent crystals. Furthermore, this high-pressure strategy can be readily expanded to additional materials. We anticipate that the welded structures will constitute an ideal system with relevance to applications in optical responses, lithium ion battery, solar cells and chemical sensing.
    ACS Nano 11/2015; DOI:10.1021/acsnano.5b05108
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    ABSTRACT: Potentiometric sensors, such as polymeric membrane, ion-selective electrodes (ISEs), have been used in the past to monitor a variety of chemical processes. However, the use of these sensors has traditionally been limited to aqueous solutions and moderate temperatures. Here we present an ISE with a high-capacity ion-exchange sensing membrane for measurements of nitrate and nitrite in the organic solvent propylene glycol at 150 ºC. It is capable of continuously measuring under these conditions for over 180 hours. We demonstrate the usefulness of this sensor by in situ monitoring of anion concentrations during the synthesis of copper and silver nanoparticles in propylene glycol using the polyol method. Ion chromatography and a colorimetric method were used to independently confirm anion concentrations measured in situ. In doing so, it was shown that in this reaction the co-ion nitrate is reduced to nitrite.
    ACS Nano 11/2015; DOI:10.1021/acsnano.5b05170
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    ABSTRACT: We present an approach towards dynamic nano-imaging: live fluorescence of cells encapsulated in a bionanoreactor is complemented with in-situ scanning electron microscopy (SEM) on an integrated microscope. This allows us to take SEM snapshots on-demand, i.e. at a specific location in time, at a desired region of interest, guided by the dynamic fluorescence imaging. We show that this approach enables direct visualization, with EM resolution, of the distribution of bio-conjugated quantum dots on cellular extensions during uptake and internalization.
    ACS Nano 11/2015; DOI:10.1021/acsnano.5b03970
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    ABSTRACT: Ultralight and strong three-dimensional (3D) silicon carbide (SiC) structures have been generated by the carbothermal reduction of SiO with a graphene foam (GF). The resulting SiC foams have an average height of 2 mm, and density ranging between 9-17 mg cm-3. They are the lightest reported SiC structures. They consist of hollow struts made from ultrathin SiC flakes, and long 1D SiC nanowires growing from the trusses, edges and defect sites between layers. AFM results revealed an average flake thickness of 2-3 nm and lateral size of 2 µm. In-situ compression tests in the scanning electron microscope (SEM) shown that, compared with most of the existing lightweight foams, the present 3D SiC exhibited superior compression strengths and significant recovery after compression strains of about 70%.
    ACS Nano 11/2015; DOI:10.1021/acsnano.5b05533
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    ABSTRACT: The sensing and differentiation of explosive molecules is key for both security and environmental monitoring. Single fluorophores are a widely used tool for explosives detection, but a fluorescent array is a more powerful tool for detecting and differentiating such molecules. By combining array elements into a single multichannel platform; faster results can be obtained from smaller amounts of sample. Here, five explosives are detected and differentiated using quantum dots as luminescent probes in a multichannel platform - 2,4-dinitrotoluene (DNT), 2,4,6-trinitrotoluene (TNT), tetryl (2,4,6-trinitrophenylmethylnitramine), cyclotrimethylenetrinitramine (RDX) and pentaerythritol tetranitrate (PETN). The sharp, variable emissions of the quantum dots, from a single excitation wavelength, make them ideal for such a system. Each colour quantum dot is functionalised with a different surface receptor via a facile ligation process. These receptors undergo non-specific interactions with the explosives, inducing variable fluorescence quenching of the quantum dots. Pattern analysis of the fluorescence quenching data allows for explosive detection and identification with limits-of-detection in the ppb range.
    ACS Nano 11/2015; DOI:10.1021/acsnano.5b06433
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    ABSTRACT: Boron nitride nanotubes (BNNTs) exhibit a range of properties that hold great potential for many fields of science and technology; however, they have inherently low chemical reactivity, making functionalization for specific applications difficult. Here we propose that covalent functionalization of BNNTs via reduction chemistry could be a highly promising and viable strategy. Through density functional theory (DFT) calculations of the electron affinity of BNNTs and their binding energies with various radicals, we reveal that their chemical reactivity can be significantly enhanced via reducing the nanotubes (i.e. negatively charging). For example, a 5.5 fold enhancement in reactivity of reduced BNNTs towards NH2 radicals was predicted relative to their neutral counterparts. The localization characteristics of the BNNT π electron system lead the excess electrons to fill the empty p orbitals of boron sites, which promote covalent bond formation with an unpaired electron from a radical molecule. In support of our theoretical findings, we also experimentally investigated the covalent alkylation of BNNTs via reduction chemistry using 1-bromohexane. The thermogravimetric measurements showed a considerable weight loss (12~14 %) only for samples alkylated using reduced BNNTs, suggesting their significantly improved reactivity over neutral BNNTs. This finding will provide an insight in developing an effective route to chemical functionalization of BNNTs.
    ACS Nano 11/2015; DOI:10.1021/acsnano.5b06523
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    ABSTRACT: Three-dimensional (3D) metal oxide superstructures have demonstrated great potentials for structure-dependent energy storage and conversion applications. Here, we reported a facile hydrothermal method for direct growth of highly-ordered single crystalline nanowire array assembled 3D orthorhombic Nb3O7(OH) superstructures and their subsequent thermal transformation into monoclinic Nb2O5 with well-preserved 3D nanowire superstructures. The performance of resultant 3D Nb3O7(OH) and Nb2O5 superstructures differed remarkably when used for energy conversion and storage applications. The thermally converted Nb2O5 superstructures as anode material of lithium-ion batteries (LiBs) showed higher capacity and excellent cycling stability compared to the Nb3O7(OH) superstructures, while directly hydrothermal grown Nb3O7(OH) nanowire superstructure film on FTO substrate as photoanode of dye-sensitized solar cells (DSSCs) without the need for further calcination exhibited an overall light conversion efficiency of 6.38%, higher than that (5.87%) of DSSCs made from the thermally converted Nb2O5 film. The high energy application performance of the niobium-based nanowire superstructures with different chemical compositions can be attributed to their large surface area, superior electron transport property and high light utilization efficiency resulting from 3D superstructure, high crystallinity and large sizes. The formation process of 3D nanowire superstructures before and after thermal treatment was investigated and discussed based on our theoretical and experimental results.
    ACS Nano 11/2015; DOI:10.1021/acsnano.5b05441
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    ABSTRACT: Biological composites are renowned for their elaborate heterogeneous architectures at multiple scales, which lead to unique combination of modulus, strength and toughness. Inspired by biological composites, mimicking the heterogeneous structural design principles of biological composites is a powerful strategy to construct high-performance structural composites. Here we creatively transfer some heterogeneous principles of biological composites to the structural design of nanocomposite hydrogels. Unique heterogeneous conductive graphene-PNIPAM-clay hydrogels are prepared through combination of inhomogeneous water removal processes, in situ free-radical polymerization and chemical reduction of graphene oxide. The nanocomposite hydrogels exhibit hierarchical layered heterogeneous architectures with alternate stacking of dense laminated layers and loose porous layers. Under tensile load, the stiff dense laminated layers serve as sacrificial layers that fracture at a relatively low strain, while the stretchable loose porous layers serve as energy dissipation layers by large extension afterwards. Such local inhomogeneous deformation of the two heterogeneous layers enables the nanocomposite hydrogels to integrate superior modulus, strength and toughness (9.69 MPa, 0.97 MPa, 5.60 MJ/m3, respectively). The study might provide meaningful enlightenments for rational structural design of future high-performance nanocomposite hydrogels.
    ACS Nano 11/2015; DOI:10.1021/acsnano.5b05120