Experimental and clinical cardiology (Exp Clin Cardiol)
Experimental and Clinical Cardiology, an international English language journal, will consider for publication original articles, short communications, letters to the editor, editorials and mini-reviews. Emphasis is given to all aspects of the cardiovascular system from basic science to clinical cardiology. Submissions will be assessed primarily on their scientific validity and merit, not on their grammatical quality. Manuscripts are received with the understanding that they are submitted solely to Experimental and Clinical Cardiology, and that none of the material contained in the manuscript has been published previously or is under consideration for publication elsewhere, excluding abstracts. The publisher reserves copyright in any medium on all published material, and material may not be reproduced without the written permission of the publisher. Statements and opinions are the responsibility of the authors.
Current impact factor: 0.76
Impact Factor Rankings
|2015 Impact Factor||Available summer 2015|
|2013 / 2014 Impact Factor||0.758|
|2012 Impact Factor||1.1|
|2011 Impact Factor||0.576|
Impact factor over time
|Website||Experimental and Clinical Cardiology website|
|Other titles||Experimental and clinical cardiology (Online), Cardiology|
|Material type||Document, Periodical, Internet resource|
|Document type||Internet Resource, Computer File, Journal / Magazine / Newspaper|
- Archiving status unclear
- Author cannot archive a post-print version
- On open access repositories
- Publisher's version/PDF must be used
- Creative Commons Attribution License 3.0
- Published source must be acknowledged
- Authors retain copyright
- All titles are open access journals
- Classification blue
Publications in this journal
- Experimental and clinical cardiology 09/2014; 20(10):6258-6270.
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ABSTRACT: To optimally improve health status after a myocardial infarction it is essential for patients to understand the seriousness of the disease and improve their self-management. Aims: To describe patients’ perceptions of preventive care, after experiencing a first episode of an acute myocardial infarction in a central hospital in Portugal and to analyze the intent to change behaviors and real changes six months after myocardial infarction. Methods: Longitudinal descriptive study; 106 patients aged between 35 and 64 years, who had cardiovascular risk factors and a first experience of myocardial infarction were selected. Data was collected in two structured interviews. Results: Of the patients, 18% had never, by their own accord, chosen to use preventive care services. During hospitalization, 43% described preventive care as a negative perception. Patients showed intent to change their habits but after discharge, they had difficulties in self-management of disease, maintaining monitoring or changing their cardiovascular risk factors such as physical activity (41%), blood pressure (37%), and eating habits (24%). Conclusions: There were considerable discrepancies between the intention and action in behavioral changes in patients after a myocardial infarction. Regarding the patients’ perceptions, there is a need to improve their involvement in the management of disease.Experimental and clinical cardiology 08/2014; 20(8).
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ABSTRACT: Coronary heart disease (CHD) is the single largest killer out of all diseases in Europe and in the US. Pathologic cardiac ischemia in CHD triggers a succession of events leading to massive destruction and loss of cardiac tissues. Thus, replacement of the damaged cardiac tissues by newly regenerated myocardium would be a therapeutic ideal for pathology modifying treatment of CHD. The aim of this study was to evaluate the ability of an active fraction isolated from Chinese herb Rosa laevigata Michx (aFRLM) in therapeutic cardiomyogenesis through promoting substantial regeneration of cardiac tissues in a myocardial infarction (MI) animal model. Our results demonstrated that oral administration of aFRLM to MI animals could significantly improve cardiac functional performance and induce myocardial regeneration replacing the necrosed cardiac tissues in a sub-clinical MI animal model. The property of the aFRLM appears to be entirely novel and may provide a potential therapeutic alternative for MI treatment.Experimental and clinical cardiology 08/2014;
- Experimental and clinical cardiology 08/2014; 20(8):2720-2747.
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ABSTRACT: Aims: to assess the diagnostic value of plasma D-dimer level assay for prediction of thrombus formation in left atrial appendage( LAA) in patients with moderate or severe mitral stenosis Methods and results: We enrolled 218 patients with isolated rheumatic mitral stenosis who were candidates for commissurotomy. Trans-esophageal echocardiography and D-dimer plasma level measurement was done in all patients. Forty five percent of the patients were in sinus rhythm. Patient with a thrombus in LAA had higher levels of D-dimer than those with without thrombus (median of 691.50 and inter-quartile range of 370.5-1839.5 vs. median of 347μg/dl and inter-quartile range: 216-642, p: 0.002). Receiver operating curve analysis yielded an optimal D-dimer cut-off level of 2100 μg/dl for detection of thrombus. This cut-off level has been associated with a specificity of 95% and a negative predictive value of 88% for the presence of thrombus in LAA. Conclusion: In rheumatic mitral stenosis, D-dimer level assay has a high specificity and negative predictive value for evaluation of clot formation in LAA. This remarkable diagnostic yield may have clinical implications. Keywords: D-dimer, thrombus, mitral stenosisExperimental and clinical cardiology 07/2014; 20(7):1808-1818/2014.
Article: MicroRNA 208 in Atrial Fibrillation[Show abstract] [Hide abstract]
ABSTRACT: Abstract MicroRNAs (miRNAs) are critical regulators of most major cellular processes and seem to play a vital role in the pathogenesis of numerous diseases including atrial fibrillation, the most commonly encountered cardiac rhythm disorder. Among the several miRNAs that appear to be involved in pathogenesis of atrial fibrillation, miRNA 208a is linked to fibrosis and proper cardiac conduction. We quantified the expression levels of miRNA 208a in left atrial appendage tissue of patients with paroxysmal (n=2), persistent (n=10), and long-standing persistent (n=7) arrhythmia using quantitative PCR. In paroxysmal atrial fibrillation, miRNA 208a was expressed moderately, whereas the expression was enhanced in persistent atrial fibrillation and significantly reduced in long-standing persistent atrial fibrillation. The difference between persistent and long-standing persistent atrial fibrillation was significant at p=0.02. The findings from our study suggest a decline in miRNA 208a expression with ongoing arrhythmia, possibly preceded by a rise in expression from paroxysmal to persistent atrial fibrillation or even long-standing persistent. The significant changes in miRNA 208a expression over the course of the disease may be used as an additional diagnostic tool to monitor the progression of atrial fibrillation.Experimental and clinical cardiology 07/2014; DOI:10.4172/2155-9880.1000325
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.