IET Nanobiotechnology (IET NANOBIOTECHNOL)

Publisher: Institution of Engineering and Technology, Institution of Engineering and Technology

Journal description

IET Nanobiotechnology covers all aspects of research and emerging technologies including, but not limited to: Fundamental theories and concepts applied to biomedical-related devices and methods at the micro- and nano-scale (including methods that employ electrokinetic, electrohydrodynamic, and optical trapping techniques); Micromachining and Microfabrication tools and techniques applied to the top-down approach to Nanobiotechnology; Nanomachining and Nanofabrication tools and techniques directed towards biomedical and biotechnological applications (e.g. applications of Atomic Force Microscopy, Scanning Probe Microscopy and related tools); Colloid chemistry applied to Nanobiotechnology (e.g. cosmetics, suntan lotions, bio-active nanoparticles); Microtechnologies such as Lab-on-Chip applied to pharmaceutical, biomedical and biotechnological applications; Techniques for probing cell physiology, cell adhesion sites and cell-cell communication; Molecular self-assembly, including concepts of supramolecular chemistry, molecular recognition, and DNA Nanotechnology; Societal issues such as health and the environment.

Current impact factor: 1.72

Impact Factor Rankings

2015 Impact Factor Available summer 2015
2013 / 2014 Impact Factor 1.723
2012 Impact Factor 1
2011 Impact Factor 1.833
2010 Impact Factor 1.857
2009 Impact Factor 2.077
2008 Impact Factor 1.562
2007 Impact Factor

Impact factor over time

Impact factor

Additional details

5-year impact 1.53
Cited half-life 4.10
Immediacy index 0.25
Eigenfactor 0.00
Article influence 0.39
Website IET Nanobiotechnology website
Other titles IET NBT, Nanobiotechnology
ISSN 1751-8741
OCLC 86085276
Material type Periodical, Internet resource
Document type Journal / Magazine / Newspaper, Internet Resource

Publisher details

Institution of Engineering and Technology

  • Pre-print
    • Author can archive a pre-print version
  • Post-print
    • Author can archive a post-print version
  • Conditions
    • Pre-print to be removed on archiving of authors post-print
    • On a non-profit server
    • Set phrase to accompany pre-print (see link below)
    • On institutional server or institutional repository
    • Publisher copyright and source must be acknowledged
    • Must link to publisher version
    • Publisher's version/PDF cannot be used
    • If funding rules apply authors may post author version in designated repository
  • Classification
    ​ green

Publications in this journal

  • IET Nanobiotechnology 07/2015;
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    ABSTRACT: Nanoparticles as solid colloidal particles are extensively studied and used as anticancer drug delivery agents because of their physical properties. This current research aims to prepare water base suspension of uncoated iron oxide nanoparticles and their biodistribution study to different organs, especially the brain, by using a single photon emission computed tomography gamma camera. The water-based suspension of iron oxide nanoparticles was synthesised by a reformed version of the co-precipitation method and labelled with Tc(99m) for intravenous injection. The nanoparticles were injected without surface modification. X-ray diffraction (XRD), energy dispersive spectrometry (EDS) and transmission electron microscope (TEM) techniques were used for characterisation. Peaks of XRD and EDS indicate that the particles are magnetite and exist in aqueous suspension. The average diameter of iron oxide nanoparticles without any surface coating determined by TEM is 10 nm. These particles are capable of evading the reticuloendothelial system and can cross the blood-brain barrier in the rabbit. The labelling efficiency of iron oxide nanoparticles labelled with Tc(99m) is 85%, which is good for the biodistribution study. The sufficient amount of iron oxide nanoparticles concentration in the brain as compared with the surrounding soft tissues and their long blood retention time indicates that the water-based suspension of iron oxide nanoparticles may be an option for drug delivery into the brain.
    IET Nanobiotechnology 06/2015; 9(3). DOI:10.1049/iet-nbt.2014.0012
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    ABSTRACT: This study aimed to analyse the components of nanocrystallites in urines of patients with uric acid (UA) stones. X-ray diffraction (XRD), Fourier transform infrared spectroscopy, high-resolution transmission electron microscopy (HRTEM), fast Fourier transformation (FFT) of HRTEM, and energy dispersive X-ray spectroscopy (EDS) were performed to analyse the components of these nanocrystallites. XRD and FFT showed that the main component of urinary nanocrystallites was UA, which contains a small amount of calcium oxalate monohydrate and phosphates. EDS showed the characteristic absorption peaks of C, O, Ca and P. The formation of UA stones was closely related to a large number of UA nanocrystallites in urine. A combination of HRTEM, FFT, EDS and XRD analyses could be performed accurately to analyse the components of urinary nanocrystallites.
    IET Nanobiotechnology 06/2015; 9(3):114-21. DOI:10.1049/iet-nbt.2014.0017
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    ABSTRACT: In this study, AC characterisation of DNA molecular wires, effects of frequency, temperature and UV irradiation on their conductivity is presented. λ-DNA molecular wires suspended between high aspect-ratio electrodes exhibit highly frequency-dependent conductivity that approaches metal-like behaviour at high frequencies (∼MHz). Detailed temperature dependence experiments were performed that traced the impedance response of λ-DNA until its denaturation. UV irradiation experiments where conductivity was lost at higher and longer UV exposures helped to establish that it is indeed λ-DNA molecular wires that generate conductivity. The subsequent renaturation of λ-DNA resulted in the recovery of current conduction, providing yet another proof of the conducting DNA molecular wire bridge. The temperature results also revealed hysteretic and bi-modal impedance responses that could make DNA a candidate for nanoelectronics components like thermal transistors and switches. Further, these experiments shed light on the charge transfer mechanism in DNA. At higher temperatures, the expected increase in thermal-induced charge hopping may account for the decrease in impedance supporting the 'charge hopping mechanism' theory. UV light, on the other hand, causes damage to GC base-pairs and phosphate groups reducing the path available both for hopping and short-range tunneling mechanisms, and hence increasing impedance - this again supporting both the 'charge hopping' and 'tunneling' mechanism theories.
    IET Nanobiotechnology 06/2015; 9(3). DOI:10.1049/iet-nbt.2014.0044
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    ABSTRACT: Self-assembly (SA) is the preferred growth mechanism in the natural world, on scales ranging from the molecular to the macro-scale. It involves the assembling of components, which governed by a set of local interaction rules, lead to the formation of a global minimum energy structure. In this survey, the authors explore the extensive research conducted to exploit SA in three domains; first, as a bottom-up approach to fabricate semiconductor heterostructures and nano-scale devices composed of carbon nanotubes and nanowires; second, for meso-scale assembly to build systems such as three-dimensional electrical networks and microelectromechanical systems by utilising capillary force, external magnetic field and so on as the binding force; and third, as an emerging means to achieve computing via tiling, biomolecular automata and logic gates. DNA, in particular, has been a molecule of choice because of its easy availability, biological importance and high programmability as a result of its highly specific component bases.
    IET Nanobiotechnology 06/2015; 9(3):122-135. DOI:10.1049/iet-nbt.2014.0020
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    ABSTRACT: The aim of this research was to test the hypothesis that the combination of profiling, treatment and a surface coating with nanoparticles will be effective at reducing checking in deck boards exposed to the weather. In this study southern pine (Pinus sp.) deck boards were machined to flat (control) and ribbed surface profiles. The specimens were treated with aqueous copper amine azole (CA-C) using a vacuum/pressure method and coated with nano-ZnO and micronised TiO2. Boards were exposed to accelerated weathering for 576 h. The number, length and width of checks that developed in the boards were quantified and the average amounts of cupping, twist and bowing occurring in the weathered wood were examined. The results of the statistical analysis showed that all of the coated ribbed decking samples had lower average check numbers, lengths and widths compared to the end-matched flat untreated specimens. Checks were also shorter and narrower in the profiled southern pine deck board than in the unprofiled specimens. Furthermore, the lowest amount of cupping, twist and bowing were observed for specimens profiled and coated with the TiO2. Therefore, the authors conclude that the coated ribbed decks looked significantly better than the flat decking.
    IET Nanobiotechnology 06/2015; 9(3):103-6. DOI:10.1049/iet-nbt.2014.0001
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    ABSTRACT: Hypercholesterolemia is an important risk factor contributing to atherosclerosis and coronary heart disease. Lactic acid bacteria have attracted much attention regarding their promising effect on serum cholesterol levels. Tellurium (Te) is a rare element that has also gained considerable interest for its biological effects. There have been some recent in vivo reports on the reduction effect of Te on cholesterol content. In this study, Lactobacillus plantarum PTCC 1058 was employed for the intracellular biosynthesis of Te NPs. The UV-visible spectrum of purified NPs showed a peak at 214 nm related to the surface plasmon resonance of the Te NPs. Transmission electron microscopy showed that spherical nanoparticles without aggregation had the average size of 45.7 nm as determined by the laser scattering method. The energy dispersive X-ray pattern confirmed the presence of Te atoms without any impurities. A significant reduction was observed in group which received L. plantarum with or without Te NPs during propylthiouracil and cholesterol diet in compare with the control group which received just propylthiouracil and cholesterol. The levels of triglycerides also remarkably decrease (p < 0.05) in mice given L. plantarum with intracellular Te NPs.
    IET Nanobiotechnology 05/2015; DOI:10.1049/iet-nbt.2014.0057
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    ABSTRACT: Hierarchical porous fibre scaffolds with mesoporous bioglasses (MBGs) and polylactic acid (PLA) were successfully fabricated by the electrospinning method. These compound scaffolds possess macropores with sizes of about 100 nm because of the solvent evaporation from the fibre and the mesoporous structure ( ∼4.0 nm) originated from MBGs. The biomineralisation ability was investigated in simulated body fluid. The fibre structure is beneficial for inducing the growth of hydroxyapatite. In addition, compared with pure MBGs, the materials (MP-1 and MP-2) exhibit a long-acting drug release process up to 140 h and the drug release process corresponds with the Fickian diffusion mechanism. With the special fibre morphology and the hierarchical porous structure, the MBGs/PLA fibre scaffolds are expected to have potential application for bone tissue repair and regeneration.
    IET Nanobiotechnology 04/2015; 9(2):58-65. DOI:10.1049/iet-nbt.2013.0011
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    ABSTRACT: The fluorescence labelling of plant hormone binding sites is an important analytical technique in research on the molecular mechanisms of plant hormone activities. The authors synthesised a jasmonic acid (JA)-conjugated ZnS:Mn quantum dot (QD) probe, with a cubic structure and average hydrodynamic sizes of about 17.0 nm. The maximum fluorescence emission of the probe was recorded at about 585 nm. The probe was used for fluorescence labelling of JA binding sites in mung bean seedling tissues. Analysis revealed that the probe exhibited high selectivity to JA binding sites and good performance in eliminating interference from background fluorescence in plant tissues. In addition, the probe did not exhibit any apparent biotoxicity, and is much more suitable than probes constructed from CdTe QDs for the analysis of biological samples.
    IET Nanobiotechnology 02/2015; 9(1):35-42. DOI:10.1049/iet-nbt.2014.0002
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    ABSTRACT: The aim of this study was to evaluate four immunoassays, based on amine-modified bovine serum albumin nanoparticles (AMBSANPs). First, the capability of nitrate absorption by AMBSANPs under different conditions was evaluated. Then, serial concentrations of pure βHCG were added to wells coated with βHCG antibody for immunoassays 1 and 2, and wells coated with βHCG aptamer for immunoassays 3 and 4. Next, AMBSANPs conjugated with βHCG antibody was added for immunoassays 1 and 3, and AMBSANPs conjugated with βHCG aptamer were added for immunoassays 2 and 4. Finally, the optical density (OD) of each well was read at 340 nm, and compared with controls. Moreover, the concentration of βHCG in the clinical samples was quantified by immunoassays 1, 2, 3, 4 and ELISA, and then compared. The effect of some serum interferences on these immunoassay methods was evaluated. The authors observed that the amount of nitrate absorption by AMBSANPs increased with an increase in H + ion concentration and temperature, and decreased with an increase in ion strength. The correlation (R(2)) between ELISA and immunoassays 1, 2, 3 and 4 were 0.97, 0.97, 0.98, 0.99, respectively. It was found that the increase in the serum interferences led to a decrease in the measured βHCG concentration.
    IET Nanobiotechnology 02/2015; 9(1):43-51. DOI:10.1049/iet-nbt.2014.0003
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    ABSTRACT: Extracellular and intracellular biosynthesis of silver nanoparticles (AgNPs) by Euglena gracilis (EG) strain and Euglena intermedia (EI) strain are reported in this study. The obtained nanoparticles showed an absorption peak approximates 420 nm in the UV-visible spectrum, corresponding to the plasmon resonance of AgNPs. According to the result of inductively coupled plasma-atomic emission spectrometer, the intakes of silver ions by EI and EG are roughly equal. The transmission electron microscope (TEM) analysis of the successful in vivo and in vitro synthesised AgNPs indicated the sizes, ranging from 6 to 24 nm and 15 to 60 nm in diameter, respectively, and a spherical-shaped polydispersal of the particles. The successful formation of AgNPs has been confirmed by energy dispersive X-ray analysis connected to the TEM. The Fourier transform infrared spectroscopy measurements reveal the presence of bioactive functional groups such as amines are found to be the capping and stabilising agents of nanoparticles. To our knowledge, this is the first report where two kinds of Euglena microalga were used as the potential source for in vivo and in vitro biosynthesis of AgNPs.
    IET Nanobiotechnology 02/2015; 9(1):19-26. DOI:10.1049/iet-nbt.2013.0062
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    ABSTRACT: Spherical macroporous poly(lactic-co-glycolic acid) (PLGA) has been synthesised using an emulsion method. Polyvinyl alcohol and Pluronic F127 have been used as dispersing and porogen agent, respectively. The diameter of the spherical PLGA is about 20 μm and the pore size of the PLGA macroporous is about 2-2.5 μm observed by scanning electron microscopy. After immersing in simulated body fluid, the PLGA materials can induce the formation of hydroxyapatite (HAP) on their surface. The HAP-PLGA has been obtained and used as the host for drug release. Furthermore, the drug-loaded samples possess the various drug release performance by adjusting the thickness of the HAP layer. This highly satisfied composite material is expected to be promising in the applications in tissue regeneration engineering.
    IET Nanobiotechnology 02/2015; 9(1):1-4. DOI:10.1049/iet-nbt.2013.0066
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    ABSTRACT: Effects were studied of vapour chamber on specific gas permeability of nanosilane (NS)-treated medium-density fibreboards (MDFs). Size range of nanoparticles was 20-80 nm. NS was used at four consumption levels of 0, 50, 100 and 150 g/kg dry wood fibres. Density of all treatments was kept constant at 0.67 g/cm(3). Specimens were kept for 18 weeks in vapourised chamber; their specific gas permeability was measured every two weeks. Results showed that extreme moisture uptake because of the biological structure of wood fibres, as well as mold and fungi growth on the specimens from the tenth week, resulted in the breaking down of the urea-formaldehyde resin; they also weakened the water-repellant effect of NS; consequently, the permeability increased significantly. It can be concluded that NS makes MDF susceptible to molds and therefore NS-treated MDF panels are not recommended for moist climates in which boards are exposed to water vapours in the air for a long time, although NS-panels primarily showed higher impermeability to water.
    IET Nanobiotechnology 02/2015; 9(1):11-8. DOI:10.1049/iet-nbt.2013.0064
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    ABSTRACT: Currently, nanometal oxides find their role in different biological applications such as tissue engineering, implant and bone replacement materials. Owing to the increased use of nanoparticles, it is necessary to understand their release and toxicity in the biological system. In this regard, three independent studies such as in vitro cytotoxicity, antioxidant activity and biocompatibility of nano- and micrometal oxide particles such as alumina (Al2O3) and silica (SiO2) are evaluated. It is evident from cell viability study that nanoAl2O3 and SiO2 particles are less toxic when compared with microAl2O3 and SiO2 to NIH 3T3 cell lines up to 200 µg/ml. Antioxidant properties of micro- and nanoAl2O3 in terms of radical scavenging percentage for micro- and nanoAl2O3 are 59.1% and 72.1%, respectively, at 100 mg. Similarly, the radical scavenging percentage of nano- and bulk SiO2 are 81.0% and 67.2%, respectively. The present study reveals that the cellular behaviour, interaction and biocompatibility of metal oxides differ with dose, particle size, contact angle and zeta potential. The present study opens up a new strategy to analyse in vitro nanotoxicity.
    IET Nanobiotechnology 02/2015; 9(1):27-34. DOI:10.1049/iet-nbt.2013.0067