Acta Paediatrica

Publisher: Blackwell Publishing

Description

  • Impact factor
    1.97
  • 5-year impact
    2.06
  • Cited half-life
    8.70
  • Immediacy index
    0.41
  • Eigenfactor
    0.02
  • Article influence
    0.67
  • Other titles
    Acta pædiatrica (Oslo, Norway: 1992: Online), Acta paediatrica
  • ISSN
    1651-2227
  • OCLC
    37664034
  • Material type
    Document, Periodical, Internet resource
  • Document type
    Internet Resource, Computer File, Journal / Magazine / Newspaper

Publisher details

Blackwell Publishing

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    • Author can archive a pre-print version
  • Post-print
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    • Some journals impose embargoes typically of 6 or 12 months, occasionally of 24 months
    • no listing of affected journals available as yet
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    • See Wiley-Blackwell entry for articles after February 2007
    • Publisher's version/PDF cannot be used
    • On author's server, institutional server or subject-based server
    • Server must be non-commercial
    • Publisher copyright and source must be acknowledged with set statement ("The definitive version is available at www.blackwell-synergy.com")
    • Articles in some journals can be made Open Access on payment of additional charge
    • 'Blackwell Publishing' is an imprint of 'Wiley'
  • Classification
    ​ yellow

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: AimIn developing countries, around 200 million children with poor development cannot excel academically. Detecting children with developmental delay is fundamental in targeting early interventions. As the lack of a convenient screening tool in Mongolia remains a significant barrier, we aimed to produce an easy-to-administer developmental screening tool in Mongolia and to validate it against an internationally recognised instrument, the Bayley Scales of Infant and Toddler Development Third Edition (Bayley-III).Methods We developed the Mongolian Rapid Baby Scale consisting of 161 items arranged under seven developmental domains for children aged from zero months 16 days to 42 months 15 days. We recruited 150 children in Ulaanbaatar, Mongolia. After conducting face and content validity of the tool, we evaluated concurrent validity.ResultsConcurrent validity ranged from high correlation (r=0.86) to very high (r=0.97) for each of the corresponding domains between the two tests. Summary statistics showed good sensitivity (81.8%) and moderate specificity (52.3%).Conclusion Our newly developed tool takes only 15 minutes to complete and is easy to administer. It demonstrated good concurrent validity and sensitivity for the screening of developmental status in young children. This innovative tool will be useful to identify children who may benefit from early interventions in Mongolia.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 12/2014;
  • Anne Marthe Boldingh, Anne L Solevåg, Jūratė Šaltytė Benth, Claus Klingenberg, Britt Nakstad
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    ABSTRACT: AimSustained inflations during initial resuscitation may help a depressed infant make a more efficient transition to air-filled lungs. This study examined whether doctors could perform sustained inflations with a self-inflating bag in high and low compliance settings and with an open or blocked pressure-relief valve.Methods We asked 43 doctors to carry out sustained inflations for more than five seconds in a manikin connected to a newborn lung simulator with randomised compliance settings. Tidal volume, inflation time, peak and mean inflating pressure were measured and 34 were retested three months later.ResultsThe majority of the doctors - 72% in the initial study and 62% in the retest -managed sustained inflations within three ventilation attempts, irrespective of lung compliance setting and years of work experience. Using a blocked pressure-relief valve produced higher tidal volume (27.8 versus 22.6ml, p<0.001), inflation time (8.9 versus 8.1s, p=0.025), peak inflating pressure (34.0 versus 28.0 cmH2O; p=0.012) and mean inflating pressure (28.1 versus 22.8 cmH2O; p<0.001).Conclusion The majority of doctors could deliver sustained inflation with a self-inflating bag in a newborn lung simulator for more than five seconds. Using a blocked pressure-relief valve resulted in higher inflation time, tidal volume and inflation pressure.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 12/2014;
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    ABSTRACT: AimFetoplacental Doppler abnormalities have been associated with increased neonatal mortality and morbidity. This study evaluated the associations between prenatal Doppler assessments and neonatal mortality and morbidity in premature infants born small for gestational age or after pre-eclampsia.Methods This was a population-based study of infants born alive at 220 - 336 weeks of gestation, a birth weight <10th percentile for gestational age and, or maternal pre-eclampsia. Doppler assessments of the umbilical artery, middle cerebral artery and ductus venosus were evaluated in 127, 125 and 95 cases respectively. Circulatory compromise was defined as absent or reversed end-diastolic velocity in the umbilical artery (AREDF), middle cerebral artery pulsatility index <2.5 percentile for gestational age and ductus venosus pulsatility index for veins >97.5 percentile.ResultsAREDF was present in 28% of the infants. This was associated with increased frequencies of neonatal sepsis and necrotising enterocolitis after adjusting for gestational age. Abnormal ductus venosus pulsatility index for veins was associated with increased risk of neonatal sepsis, but only in combination with AREDF. These associations were only present when gestational age was <28 weeks.ConclusionAREDF was associated with increased neonatal morbidity in premature infants born small for gestational age or after pre-eclampsia.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 12/2014;
  • Nakul Vijakkhana, Tanaporn Wilaisakditipakorn, Kitja Ruedeekhajorn, Chandhita Pruksananonda, Weerasak Chonchaiya
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    ABSTRACT: AimTo investigate whether evening media exposure, bedroom media use, and night-time sleep duration at age of six months are associated with night-time sleep duration in 12-month-old Thai infants.Methods We enrolled 208 infants in this study at six-months-of-age. They were followed-up at 12-months-of-age. A sleep diary was used to document the infant's sleep onset and wake time at each visit. Night-time sleep duration was then calculated at both ages. Screen media exposure in the household was assessed in depth at both visits.ResultsInfants who were exposed to screen media in the evening at 12-months-of-age had a 28-minute decrease in 12-month night-time sleep duration on weekdays. Moreover, infants who were exposed to screen media in the evening at six months and 12 months had shorter 12-month night-time sleep duration compared with those who were not exposed to screen media after 7pm at both ages. Night-time sleep duration at 12 months of age was also directly related to six-month night-time sleep duration.Conclusion Infants exposed to screen media in the evening at 12-months-of-age had decreased 12-month night-time sleep duration. To promote good sleep hygiene and optimal sleep for infants at this age, screen media exposure after 7pm should be avoided.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 12/2014;
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    ABSTRACT: AimLong-term electroencephalogram (EEG) recording is increasingly being used in the neonatal period, but the application and maintenance of the EEG electrodes is challenging, especially in preterm infants. This study proposes a practical method of electrode application that can be used in the neonatal intensive care unit (NICU).MethodEEG recording in preterm infants of <32 weeks of gestational age is often challenging and requires careful preparation and strict adherence to NICU protocols. An effective technique for EEG application in preterm infants is to use pre-packaged, sterile, disposable, flat-surfaced EEG electrodes. The use of these electrodes in combination with a continuous positive airway pressure hat provides good security for electrodes and good quality EEG recordings. It also limits the handling of the infant, while strictly adhering to infection control policies.ResultsLong-term monitoring for greater than 72 hours has been achieved using this technique. Important steps to consider are efficient preparation of the recording machine and materials, careful electrode application and infection control.ConclusionA fast and effective method of EEG electrode placement is required for neonatal EEG monitoring. The practical techniques described in this paper outline a reliable method of EEG electrode placement, suitable for even extremely preterm infants.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 12/2014;
  • Acta Paediatrica 12/2014; 103(12).
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    ABSTRACT: We read with great interest the article by Brødsgaard et al (1) that reported the effectiveness of topical clobetasol propionate for treating umbilical granuloma in infants. The authors concluded that topical application of clobetasol propionate cream (0.05%) was as effective as topical silver nitrate (99%) for treating umbilical granuloma, with self-limiting mild side effects. They said that the advantage of this approach was that it could be applied by the parents at home, compared to silver nitrate, which needed to be applied in the clinic setting.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 11/2014;
  • [Show abstract] [Hide abstract]
    ABSTRACT: Hospitalised children are at increased risk of malnutrition and preterm infants, in particular, often experience poor growth (1) This may be partly attributed to variability in nutritional care and a failure to meet nutritional targets, with the extent of nutritional deficits related to the degree of postnatal growth failure seen (2). One strategy to address this is the provision of specialist nutritional support while the infant is in the neonatal intensive care unit (NICU) (3) and, in relation to this, the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) recommends the implementation of specialist paediatric nutrition support teams in hospital, with their role including nutritional screening (4).This article is protected by copyright. All rights reserved.
    Acta Paediatrica 11/2014;
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    ABSTRACT: AimAsthma is one of the most common chronic paediatric diseases worldwide and affects different dimensions of health-related quality of life. This study tested the feasibility and convergent validity of using EQ-5D-Y instrument on children and adolescents with asthma.MethodsA cross-sectional design was chosen and children with asthma, aged from eight to 16-years-of-age, were recruited from clinics in Stockholm, Sweden. To test convergent validity, the EQ-5D-Y instrument was combined with the Paediatric Quality of Life Questionnaire.ResultsThe EQ-5D-Y proved feasible as nearly 96% of the 94 respondents completed all items on the questionnaire. High and moderate correlations between the two instruments were found for the dimensions of ‘doing usual activities’ and ‘activity limitations’ and for ‘having pain or discomfort’ and ‘symptoms’. The visual analogue scale of the ED-5D-Y correlated with the Paediatric Quality of Life Questionnaire total score and the self-rated health question. The dimensions on the EQ-5D-Y with most reported problems were ‘usual activities’, ‘pain or discomfort’ and ‘worried, sad or unhappy’.Conclusion The EQ-5D-Y instrument seemed to provide feasiblity and convergent validity for measuring health-related quality of life in children and adolescents with asthma.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 11/2014;
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    ABSTRACT: AimThe rate of paediatric occult bacteraemia after the introduction of the 13-valent pneumococcal conjugated vaccine is relatively unknown. We determined the rate, and identified isolated pathogens, in children aged three to 36 months who presented to a paediatric emergency department with fever, but otherwise appeared well. We also analysed the yield of laboratory parameters traditionally considered risk factors for occult bacteraemia.Methods Children aged three to 36 months who were febrile, but otherwise appeared well, were included if they had blood tests in the paediatric emergency department between April 2010 and September 2012.ResultsOf the 591 patients, only six (1.0%) had a true bacterial pathogen and three of those were Streptococcus pneumoniae (0.5%). None of the children with pneumococcal bacteraemia had been immunised. The contaminant rate was 2.7% and an elevated band count was the best predictor of occult bacteraemia, with positive and negative likelihood ratios of 10 and 0.4, respectively. The yield of the other laboratory parameters was very limited.Conclusions In the era of the 13-valent pneumococcal conjugated vaccine, occult bacteraemia is an uncommon event in febrile children aged three to 36 who otherwise appear well and close follow-up should replace blood analysis in such cases.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 11/2014;
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    ABSTRACT: AimThe two-thumb encircling (TTE) technique often results in suboptimal cardiac compression and does not meet the requirements of current resuscitation guidelines. We compared this technique with the vertical two-thumb (VTT) technique, our novel modification of the TTE technique.Methods This was a prospective randomised crossover simulation study of out-of-hospital infant cardiopulmonary resuscitation (CPR). Participants who had completed a basic life support course performed 10 cycles of cardiac compressions on a manikin for each technique.ResultsWe enrolled 36 medical doctors who had applied for a hospital internship in this study. The VTT generated significantly higher pressure than the TTE and the pressure difference ranged from 26.8-62.9mmHg for each cycle, with a mean difference of 43.5mmHg (95% CI, 37.8-49.2). The difference in pressure showed a tendency to increase with increasing cycles of cardiac compressions. The participants’ heart and respiratory rate was higher with the VTT, but they said that it was easier to perform cardiac compressions with this technique.Conclusion The VTT technique generated more pressure than the TTE technique in a simulated model of infant out-of-hospital CPR. It can provide an alternative compression technique for effective infant CPR, especially for the rescuers with small hands or a weak grip.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 11/2014;
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    ABSTRACT: AimThe aim of this study was to investigate whether scrubbing the hub of intravenous catheters with an alcohol wipe for 15 seconds could reduce the incidence of neonatal sepsis in a level-three neonatal intensive care unit.Methods We studied the incidence of neonatal sepsis caused by coagulase negative staphylococci (CoNS) for 16.5 months before the initiative was launched on 15 May 2012 and then for a further 8.5 months after it was introduced. The hub routine was applied to all intravenous catheters.ResultsDuring the control period before the initiative was launched, there were nine cases of CoNS sepsis compared with no cases after it was introduced, resulting in a decrease in sepsis incidence from 1.5% to 0% with a risk reduction of 1.5% (0.53-2.58%) (p=0.06). In the preterm infant population, the incidence of sepsis decreased from 3.6% to 0% (1.1-6%) (p=0.11).Conclusion Scrubbing the hub of intravenous catheters with an alcohol wipe for 15 seconds seemed to be an efficient way of preventing sepsis caused by CoNS in newborn infants. However, the evidence for the benefits will remain weak until a large randomised trial has been completed.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 11/2014;
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    ABSTRACT: In a previous short communication published in this journal, we reported that pregnant women of Somali origin, living in the county of Stockholm, Sweden, had severe vitamin D deficiency (1). The study group consisted of 20 women, consecutively asked during their first visit to the antenatal clinic if they would participate in a study of vitamin D levels during pregnancy. The vitamin D levels of the 20 women of Somali origin were compared with an ethnic Swedish group of 20 pregnant women residing in the same county. The median level of serum 25-hydroxy-vitamin D (S-25-OHD) was significantly lower in women of Somali origin (11 nmol/L) than ethnic Swedish women (70 nmol/L).This article is protected by copyright. All rights reserved.
    Acta Paediatrica 11/2014;
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    ABSTRACT: AimMethods to improve the mental development of extremely low birth weight (ELBW) children are currently lacking. We assessed the effects of long-term supplementation of alpha-Tocopherol on the neurological development of 259 school-aged ELBW children.MethodsELBW participants were divided into three groups: group A with no alpha-Tocopherol supplementation (n=121); group B with supplementation for less than six months (n=104) and group C with supplementation for more than six months (n=34). We analysed the participants’ data at birth and between the ages of one-and-a-half to eight years and evaluated potential factors associated with intellectual disabilities.ResultsChildren from group C had the best outcome. The groups’ mean gestational weeks and mean ventilator days were: 27.5 weeks, 16.1 days (group A); 25.7 weeks, 41.7 days (group B), and 25.1 weeks, 75.5 days (group C). Multivariate regression analysis revealed that the odds ratios for impaired mental development at eight years were 1.5 in group B and 0.19 (p=0.017) in group C, compared to 1.0 in group A. The association between duration of alpha-Tocopherol administration and performance intelligence quotient (IQ) was dose dependent (p=0.03).Conclusion Long-term supplementation of alpha-Tocopherol appeared to improve mental development, in particular, performance IQ, in school-aged ELBW children.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 11/2014;
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    ABSTRACT: The Gateway Hypothesis describes how tobacco or alcohol use precedes marijuana and other illicit drug use. We review the epidemiological data, explore the underlying molecular mechanisms in mice and discuss the societal implications of the Hypothesis, including the use of e-cigarettes by young people. Conclusion. Our mouse model identifies biological processes underlying the Hypothesis, showing that nicotine is a gateway drug that exerts a priming effect on cocaine through increased global acetylation in the striatum.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 11/2014;
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    ABSTRACT: Aimhe aim of thisstudy was to examine the overlap between child maltreatment types and theirassociation with quality of life amongschool children.MethodsA national cross-sectional study of 3,202 grade nine Swedish pupils of 15-years-of-agewas carried out in 2011 with an 84% response rate.Data were analysed usingPearson chi-squareandmultiple linear regression analyses.ResultsOf the total sample, 650 children (20%) reported at least one type of maltreatment.There was a large degree of overlap between maltreatment types.In particular,neglect and witnessing intimate partner violence overlapped with most other types of maltreatment.There was a significant relationship between the degree of abuse and multi-type maltreatment. Results showeda linear relationship between the number of types ofmaltreatment and quality of life (p<0.001), indicating a dose-response relationship.Conclusion The results emphasise the negative impact of child maltreatment on children's lives and highlight the importance of taking the broad spectrum of child maltreatment into account in both research and practice. A more comprehensive assessment of the width of maltreatment among professionals may help to identify the most seriously maltreated children and lead to an improved ability to target intervention and prevention atthese children.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 11/2014;
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    ABSTRACT: AimVery little is known about risk predictors for the development of reduced processing speed, which can cause intellectual problems in later life. This study identified risk predictors at five-years-of-age in a population-based cohort of very preterm infants.Methods Between January 2003 and August 2006 all preterm infants born before 32 weeks of gestation in Tyrol were prospectively enrolled (n=223) and 161 underwent a detailed examination at five-years-of-age, including a cognitive assessment using the Wechsler Preschool and Primary Scale of Intelligence, third edition. The processing speed quotient is calculated on the basis of two subtests that assess symbol search and coding. The association between prenatal and postnatal factors and reduced processing speed was analysed by means of logistic regression analysis.ResultsOf 161 children tested, 55 (34.2%) showed reduced processing speed. In 55.6% (n=30) of these children, reduced processing speed was related to full-scale intelligence quotient scores of less than 85. Smoking in pregnancy, steroids for chronic lung disease and intracerebral haemorrhage predicted reduced processing speed at five-years-of-age.Conclusion More than a third of the very preterm children we tested showed reduced processing speed at five-years-of-age and predictors were typical complications of prematurity and smoking in pregnancy.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 11/2014;
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    ABSTRACT: AimPrematurity is associated with features of metabolic syndrome in young adulthood. We investigated the body composition and blood pressure of children born preterm.MethodsA longitudinal, observational study was conducted with preterm infants who had a birth weight of less than <1500g and a gestational age of less than 32 weeks. Growth and body composition were assessed by air-displacement plethysmography at term equivalent age and at school age and were compared to those of 61 healthy, term breastfed subjects.ResultsA total of 63 preterm infants were enrolled. At term equivalent age, growth and fat free mass were lower in preterm infants than in term newborns, but fat mass was higher. At five-years-of-age, children born preterm were still lighter and shorter than children born at term. When the results were analysed by gender, the fat free mass index was lower in boys born preterm than in their peers (12.1±1.1 versus 13.0±1.0 kg/h2 P<0.005) whereas no difference was detected among girls. Diastolic blood pressure was higher in children born preterm than in children born at term (61.14±7.8 vs 56.69±8.2 mmHg, p=0.009).Conclusion Boys born preterm showed a relative lack of fat free mass at school age compared to their peers.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 11/2014;