Acta Paediatrica

Publisher: Blackwell Publishing

Journal description

Current impact factor: 1.97

Impact Factor Rankings

2015 Impact Factor Available summer 2015
2011 Impact Factor 2.073

Additional details

5-year impact 2.06
Cited half-life 8.70
Immediacy index 0.41
Eigenfactor 0.02
Article influence 0.67
Other titles Acta pædiatrica (Oslo, Norway: 1992: Online), Acta paediatrica
ISSN 1651-2227
OCLC 37664034
Material type Document, Periodical, Internet resource
Document type Internet Resource, Computer File, Journal / Magazine / Newspaper

Publisher details

Blackwell Publishing

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    • 'Blackwell Publishing' is an imprint of 'Wiley'
  • Classification
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Publications in this journal

  • Acta Paediatrica 03/2015; 104(3).
  • Acta Paediatrica 02/2015; 104(2).
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    ABSTRACT: Practical Algorithms in Pediatric Gastroenterology is a new addition to the series on Practical Algorithms in Pediatrics. Edited by Ron Shaoul, its 110 pages provide 51 algorithms for managing common complaints, together with laboratory values and diagnoses in paediatric gastroenterology, hepatology and nutrition. The book is spiral-bound in an A4-landscape format and each spread features an algorithm on the upper page and explanatory text and a selection of suggested references on the lower page. According to the preface, the algorithms are meant to provide a collection of pragmatic texts to be used by the inexperienced physician at the patient's bedside. The algorithms are presented as checklists and show how to approach a clinical scenario in a logical, concise and cost-effective way. The book is a mixture of evidence-based guidelines and advice based on experience from a group of internationally renowned paediatric gastroenterologists.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 02/2015;
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    ABSTRACT: AimThere is a scarcity of data on postnatal growth in children with CHARGE syndrome, a genetic disorder. This study analysed spontaneous growth and weight in German children with CHARGE from birth to the age of six years.Methods This was a retrospective analysis of 19 children, nine females and 10 males, using data from child health records. Standard deviation scores (SDS) were calculated based on Swiss references.ResultsThe median birth weight was 2,950g (-0.78 SDS) and the birth length was 49cm (-0.5 SDS). There was a significant loss of median body length, at around four-weeks-of-age from -0.5 to -2.3 SDS (p<0.05). At one year, the median length was -2.6 SDS and it remained low until five-years-of-age when the lowest value was found to be -2.8 SDS. There was a significant increase in median body mass index (BMI) from -1.15 SDS at one year to -0.15 SDS at five years (p<0.01).Conclusion Children with CHARGE syndrome displayed almost normal length and weight data at birth, with just one of the 19 infants having below average length for gestational age. However, postnatal growth was retarded during infancy and childhood and the increase in BMI-SDS did not correlate with growth.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 02/2015;
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    ABSTRACT: The American Academy of Pediatrics has now published the third edition of this practical and useful guide, which provides teachers, childcare providers, families and public health and health professionals with useful advice on preventing and controlling the spread of communicable infections. The book contains 11 chapters, and 251 pages, including the glossary and index, and the information is based on the latest recommendations from the American Academy of Pediatrics, American Public Health Association, Centers for Disease Control and Prevention and the Maternal and Child Health Bureau of the US Department of Health and Human Service.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 02/2015;
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    ABSTRACT: AimFemoral venous catheters (FVCs) provide multi-lumen access in critically ill infants with difficult venous access. This paper reports our experiences of using a modified Seldinger technique to insert FVCs in our neonatal unit.Methods This was a retrospective case series of 34 infants who had FVCs inserted using the modified Seldinger Technique during a four-year period.ResultsThe median (range) postnatal age and weight at the time of insertion was 66 days (1-314), and 3,080 grams (865-8,000). The FVC remained in-situ for a median duration of 21 days (1-63). There were nine infants who died while the FVC remained in-situ. The FVCs were removed from four infants due to complications. In three cases they became dislodged and in one case the line became blocked. In 16 infants, the FVC was removed when it was no longer required and one infant was transferred out of the unit with the FVC in-situ. Transient venous congestion of the distal limb occurred in four infants. In one infant, the FVC was accidently placed in the femoral artery and removed without complications.ConclusionsFVC insertion using a modified Seldinger technique appeared to provide alternate and immediate central venous access in critically ill infants.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 02/2015;
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    ABSTRACT: AimThis study explored neonatal morbidity and mortality in hospitalised patients in central Vietnam and risk factors associated with mortality.Methods We conducted a prospective cohort study of all newborn infants (<28 days) hospitalised in a neonatal unit over a one-year period and followed until discharge. The main outcome measures were case fatality rate and the rate of different clinical diagnoses.ResultsThere were 2,555 admissions during the study period. The leading primary causes of admissions were infections (41%), haematological problems such as jaundice (23%) and prematurity and its complications (18%). The overall case fatality rate was 8.6% and it was 59% among very low birth weight (<1,500 grams) neonates. Mortality was inversely associated with birth weight and gestational age. Of the 220 deaths, 57% occurred within the first seven days of life. Although the causes of death were often multifactorial, the leading primary causes were infections (32%), prematurity and its complications (25%), birth defects (24%) and birth asphyxia (6%). Risk factors associated with death were being outborn, early gestational age, small for gestational age, confirmed sepsis and birth defects.Conclusion Mortality rates were high among hospitalised neonates in central Vietnam and this paper suggests interventions that might improve outcomes.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 02/2015;
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    ABSTRACT: AimTo examine associations between maternal NICU visitation rates, maternal psychological distress (“distress”), and preterm infant outcome post-NICU discharge in a contemporary cohort of very low birth weight (VLBW) infants.Methods This was a prospective study of 69 mothers and their VLBW infants. Distress was assessed 1 month post-birth, 2 weeks prior to NICU discharge and after NICU discharge at 4 months corrected age [CA]. Maternal NICU visitation rates were calculated for the first 2 weeks and 1 month post-birth as well as for the entire NICU hospitalization. Regression analyses adjusted for the impact of 1. maternal and infant characteristics and distress on maternal visitation rates and 2. the impact of visitation on long-term maternal distress, and rates of infant clinic attendance and rehospitalization.ResultsGreater number of children in the home, maternal exposure to a greater number of potentially traumatic events prior to childbirth, and lower maternal anxiety consistently predicted lower visitation rate. Lower maternal visitation rate predicted higher maternal depression scores at infants’ 4 month CA visit. Maternal NICU visitation rate did not predict post-NICU discharge infant clinic attendance or rehospitalization.Conclusion Distress is an important predictor of visitation. In turn, visitation is associated with long-term maternal distress.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 02/2015;
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    ABSTRACT: AimA serious inflammatory process is suspected when C-reactive protein (CRP) is very high and we established the causes and outcomes when CRP was greater than 100 mg/L in neonates.Methods We retrospectively reviewed all 277 episodes where CRP exceeded 100mg/L between January 2007 and December 2011 at a tertiary neonatal unit.ResultsOf the 6,025 neonates admitted during the study period, 258 had CRP >100mg/L at least once. The overall mortality rate was 44/258 (17%); 36 died within seven days of CRP >100mg/L and 34 were extremely preterm infants. CRP exceeded 100mg/L in 106 infants within the first three days of life - 74 term, 25 preterm and seven extremely preterm - with no infection identified in 81%. In contrast, infections were found in 87% of the 171 episodes from day four of life - 129 extremely preterm, 23 preterm and 19 term - predominantly Coagulase-negative staphylococcus sepsis and necrotising enterocolitis.Conclusion Markedly elevated CRP in the first three days of life was most likely to affect term neonates (74/106) with no infectious cause (81%). However, CRP >100mg/L from the fourth day of life was most likely to affect extremely preterm neonates (129/171) and have an infectious cause (87%).This article is protected by copyright. All rights reserved.
    Acta Paediatrica 02/2015;
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    ABSTRACT: Off-label and unlicensed drug use to treat children is widespread in various countries (1). Because of insufficient clinical trials in pediatric population, health professionals are forced to extrapolate the results of studies carried out on adults. A systematic review including thirty international studies on off-label/unlicensed (OLUL) neonatal prescription shows the rates of such usage ranging from 55 to 80% (2). In France, data of such prescription in neonates is lacking. For that reason, we aimed to update information on the extent of OLUL prescriptions in neonates.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 02/2015;
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    ABSTRACT: AimThe aims of this study were to describe the characteristics of peripheral venous catheters (PVCs), including dwell time and reasons for removal, and explore predictors for PVC-related complications.Methods We included PVCs in 2,032 children - 484 neonatal and 1548 paediatric – from 12 inpatient units. Data were retrieved from the patient record system and predictors for complications were explored using logistic regression analyses.ResultsJust over one-third (35.4%) of the PVCs were removed due to complications, in particular infiltration and occlusion (51.9 and 48.4/1,000 PVC days, respectively). PVC survival time was shorter in neonatal than paediatric patients (four versus five days) and infiltration was more frequent in neonatal patients (92.8 versus 38.7/1,000 PVC days). Infiltration in neonatal patients was associated with PVC insertion at nighttime (odds ratio 1.80) and in younger paediatric patients (OR 0.95) and PVCs in the bend of the arm (OR 1.51). In neonatal and paediatric patients occlusion was associated with longer dwell time (OR 1.32 and 1.22 respectively) and PVCs in the ankle (OR 5.00 and 3.54) or foot (OR 3.47 and 2.00).ConclusionPVC-related complications, particularly infiltration and occlusion, were more common in hospitalised children but decreased with the child's age.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 02/2015;
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    ABSTRACT: AimThis randomised trial compared the energy costs of providing incubated preterm infants born before 32 weeks of gestation with homeothermia using either air temperature control (ATC) or skin servocontrol (SSC).Methods We studied 38 incubated preterm infants for the first 11 days of life, calculating the frequency of hypothermia (<36.0°C), hyperthermia (> 37.5°C) and thermal challenge, together with energy costs, based on a change in incubator air temperature of 2°C above or below thermoneutrality.ResultsThe daily mean incubator air temperature was higher in ATC than SSC (p<0.05) for the first six days and the mean body temperature was higher in ATC (37.0±0.03°C) than SSC (36.8±0.02; p<0.01) over the whole study period The frequency of moderate hyperthermia was higher in ATC (p<0.001), whereas warm and cold thermal challenges were higher in SSC (p<0.001). The two groups did not differ in terms of energy costs. The time to recover birth weight was shorter in ATC (p <0.05).Conclusion In incubators using ATC, a body temperature of 37°C was associated with lower energy costs and greater weight gain at 11 days of life for preterm infants. Future studies should test SSC shielded abdominal skin temperature set to 37°C.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 02/2015;
  • Acta Paediatrica 02/2015; 104(2).
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    ABSTRACT: AimExisting studies suggest that weight and body composition of parents influence the size and body composition of their offspring, but are often inconclusive and conducted by means of inappropriate body composition methodology. Our aim was to study infant size and body composition variables in relation to body composition variables of their mothers and fathers in a well-nourished population using an accurate methodology.Methods Between 2008 and 2011 we used air displacement plethysmography to measure the body composition of 209 parent-infant-units. Parents were measured when women were in gestational week 32. Their healthy, singleton, full-term infants were measured at one week.ResultsInfant fat-free mass in grams was positively related (P≤0.007) to the fat-free mass in kilograms of the mothers (15.6 g/kg) and the fathers (9.1 g/kg). Furthermore, the fat mass of the daughters, but not of the sons, was positively related to the fat mass of the mothers (5.8 g/kg, P=0.007).Conclusion This study found associations between the fat-free mass of parents and infants and an association between the fat mass of mothers and their infant girls. These findings may help to understand early life factors behind overweight and obesity.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 01/2015;
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    ABSTRACT: Guidelines for neonatology consultations during preterm labor at extremely low gestational ages state the goal of this counseling is to assist parental decision-making by providing “the most accurate prognostic morbidity and mortality data available for their infant” (1). Parents in this gray zone have serious decisions to make about what they believe to be in the best interest of their baby, and these guidelines aim to facilitate parental informed consent or refusal of neonatal resuscitation and intensive care. Much less attention has been paid to the large number of neonatology consultations that occur during preterm labor beyond the gray zone, when parents are no longer allowed to refuse life-sustaining interventions for their baby.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 01/2015;
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    ABSTRACT: Elevated levels of end-tidal carbon monoxide corrected for inhaled carbon monoxide (ETCOc), have been correlated with blood carboxyhemoglobin corrected for inhaled carbon monoxide (COHbc) and increased bilirubin production in both healthy newborn infants and those with haemolysis. Elevated bilirubin production has also been reported in infants born premature, born to mothers with diabetes, with bruising or birth trauma, with iso-immune haemolytic disorders, such as maternal-fetal blood group incompatibilities with ABO, Rh, or other minor groups, glucose-6-phosphate dehydrogenase (G6PD) deficiency, structural and functional red blood cell abnormalities and perinatal sepsis (1-6). The 2004 American Academy of Pediatrics (AAP) guideline (7) specifically recommends that ETCOc measurements be used to identify the presence of haemolysis in infants and their subsequent risk for hyperbilirubinemia based on observations that heme degradation from senescing red blood cells leads to the equimolar production of carbon monoxide (CO) and bilirubin in the absence of exposure to high ambient CO or active tissue injury (8).This article is protected by copyright. All rights reserved.
    Acta Paediatrica 01/2015;
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    ABSTRACT: AimOur clinical observations raised concerns that teenagers and young people with neurofibromatosis type 1 (NF1) might feel lonely and we decided to investigate their experiences and compare them with unaffected siblings. We also assessed predictive factors of loneliness.Methods We evaluated 60 NF1 patients aged 17 (± 3.1) years and 23 siblings aged 17 (± 2.9) years with a self-report questionnaire that assessed loneliness, depression, shyness, self-esteem, social support, bullying and difficulties making friends. Objective assessments of NF1 disease severity and visibility and somatic NF1-related and social support-related variables were carried out. Multiple linear regression analysis was performed.ResultsOf the 60 patients with NF1, 11 (18%; CI: 8-28%) said they felt lonely often or always and felt a higher degree of loneliness, but none of the siblings said they felt lonely. Predictors of loneliness were depression, shyness, bullying, self-perceived conception of illness burden and a low level of social support from friends.Conclusion Teenagers and young adults with NF1 experienced a higher prevalence and higher degree of loneliness than siblings of NF1 patients. As loneliness affects social, affective and cognitive functions, increased attention on loneliness and the predictive factors described in this study are required.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 01/2015;
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    ABSTRACT: AimThe aim of this study was to examine the association between allergic bronchopulmonary aspergillosis (ABPA) and poorly controlled asthma in children and appraise the diagnostic criteria.Methods The study included 100 children with poorly controlled asthma. We diagnosed ABPA using the Aspergillus skin test, pulmonary function test, total and specific Immunoglobulin E (IgE) to Aspergillus fumigatus, chest radiograph and high resolution computed tomography. Patients were diagnosed and classified according to the Rosenberg-Patterson criteria for ABPA. The cut-off value for total serum IgE was calculated by receiver operating characteristics curve analysis.ResultsOut of 100 children with poorly controlled asthma, 26 patients were ABPA positive. There was a significant difference in the forced expiratory volume in one second/forced vital capacity ratio between ABPA positive (0.78 ± 0.14) and negative (0.87±0.15) children (p=0.008). ABPA positive children were categorised as seropositive, central bronchiectasis and other radiological findings. The receiver operating characteristics curve was constructed and a value of 1200 IU/mL of total IgE was observed, with 88.5% sensitivity and 70.5% specificity.Conclusion This study showed an association between ABPA and poorly controlled asthma in children and suggests a higher cut-off value of total IgE for the diagnosis of ABPA.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 01/2015;
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    ABSTRACT: AimThis study determined the influence of prematurity on the manifestation and treatment of neonatal abstinence syndrome (NAS).Methods This was a medical record review of Australian infants exposed to opiates in 2004 and 2007. Finnegan scores were obtained for 215/361(59%) preterm infants under 37 weeks’ gestation and 694/1,178 (59%) term infants.ResultsThe mean and standard deviation (SD) gestational ages were 34(3) and 38(3) weeks for preterm and term infants, respectively. Maternal daily methadone doses were similar for the preterm and term infants with a mean (SD) of 79mg (39) versus 72mg (38) (p=0.06). Maximum Finnegan scores were significantly lower in preterm infants (10 versus 11, p=0.01), scores were positively correlated with gestation and fewer preterm infants were medicated for NAS (40% versus 48% p=0.05). Maximum median daily and interquartile range morphine doses were lower for preterm than term infants (0.5mg/kg/day (0.3-0.6) versus 0.5mg/kg/day (0.4-0.7), p=0.02).Conclusion Preterm infants were just as likely to be monitored for withdrawal as term infants, but their Finnegan scores were lower and fewer preterm infants were treated for NAS. Whether this indicates decreased NAS severity or physiological immaturity is uncertain. Other means of evaluating NAS in preterm infants are warranted, especially long-term outcomes.This article is protected by copyright. All rights reserved.
    Acta Paediatrica 01/2015;