Heart Rhythm (HEART RHYTHM)

Publisher: Heart Rhythm Society; Cardiac Electrophysiology Society, Elsevier

Journal description

Heart Rhythm is a unique journal that integrates the entire cardiac electrophysiology (EP) community from basic to clinical academic researchers, to private practitioners, engineers, allied professionals, industry, and trainees, all of whom are vital and interdependent members of our EP community. The Journal addresses a broad range of topics that affect our EP world. Our major focus is on original research and therapy of heart rhythm disorders, including mechanisms and electrophysiology, both clinical and experimental, genetics, ablation, devices, drugs, and surgery. Other sections include Contemporary and Historical Reviews, unique Case Reports, Viewpoints, Cell to Bedside, Hands On, Featured Arrhythmias, Images with videos viewable on the Internet, Pacing/ICD Problems, Creative Concepts, Humanism in Medicine, EP News, Editorial Commentaries, Basic/Clinical Implications, Historical Vignettes, and Ten Questions for Allied Professionals. As the Official Journal of the Heart Rhythm Society and the Cardiac Electrophysiology Society, we also publish the Plenary address and the Douglas P. Zipes Lecture given at the annual Scientific Sessions of the Heart Rhythm Society, as well as the Gordon K. Moe Lecture presented at the annual Cardiac Electrophysiology Society meeting.

Current impact factor: 5.08

Impact Factor Rankings

2015 Impact Factor Available summer 2016
2014 Impact Factor 5.076
2013 Impact Factor 4.918
2012 Impact Factor 5.045
2011 Impact Factor 4.102
2010 Impact Factor 4.246
2009 Impact Factor 4.559
2008 Impact Factor 4.444
2006 Impact Factor 3.777
2005 Impact Factor 2.667
2004 Impact Factor

Impact factor over time

Impact factor

Additional details

5-year impact 4.51
Cited half-life 4.30
Immediacy index 1.05
Eigenfactor 0.04
Article influence 1.83
Website Heart Rhythm website
Other titles Heart rhythm
ISSN 1547-5271
OCLC 53439711
Material type Periodical, Internet resource
Document type Journal / Magazine / Newspaper, Internet Resource

Publisher details


  • Pre-print
    • Author can archive a pre-print version
  • Post-print
    • Author can archive a post-print version
  • Conditions
    • Authors pre-print on any website, including arXiv and RePEC
    • Author's post-print on author's personal website immediately
    • Author's post-print on open access repository after an embargo period of between 12 months and 48 months
    • Permitted deposit due to Funding Body, Institutional and Governmental policy or mandate, may be required to comply with embargo periods of 12 months to 48 months
    • Author's post-print may be used to update arXiv and RepEC
    • Publisher's version/PDF cannot be used
    • Must link to publisher version with DOI
    • Author's post-print must be released with a Creative Commons Attribution Non-Commercial No Derivatives License
    • Publisher last reviewed on 03/06/2015
  • Classification

Publications in this journal

  • Heart Rhythm 09/2015; DOI:10.1016/j.hrcr.2014.12.015
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    ABSTRACT: The QT interval is a risk marker for cardiac events such as TdP. However, QT measurements obtained from a 12-lead ECG during clinic hours may not capture the full extent of a patient's daily QT range. We evaluated the utility of 24-hour Holter ECG recording in patients with long QT syndrome to identify dynamic changes in the heart-rate corrected QT interval, and we investigated methods of visualizing the resulting data sets. Beat-to-beat QTc (Bazett) intervals were automatically measured across 24-hour Holters from 202 LQT1, 89 LQT2, 14 LQT3 genotyped patients and a reference group of 200 healthy individuals. We measured the percentage of beats with QTc greater than the gender-specific threshold (QTc>470ms in women and QTc>450ms in men). The percentage of beats with QTc prolongation was determined across the 24-hour recordings. Based on the median percentage of heart beats per patient with QTc prolongation, LQT1 patients showed more frequent QTc prolongation during the day (~3PM) than they did at night (~3AM): 97% vs. 48%, p~10(-4) for men, 68% vs. 30%, p~10(-5) for women. LQT2 patients showed less frequent QTc prolongation during the day, compared to nighttime: 87% vs. 100%, p~10(-4) for men, 62% vs. 100%, p~10(-3) for women. In patients with genotype positive LQTS, significant differences exist in the degree of daytime and nocturnal QTc prolongation. Holter monitoring using the "QT clock" concept may provide an easy, fast, and accurate method to assess the true personalized burden of QTc prolongation. Copyright © 2015. Published by Elsevier Inc.
    Heart Rhythm 08/2015; DOI:10.1016/j.hrthm.2015.08.037
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    ABSTRACT: Background: Gain-of-function (GOF) mutations in the KATP channel subunits Kir6.1 and SUR2 cause Cantu syndrome (CS), a disease characterized by multiple cardiovascular abnormalities. Objective: To better understand the electrophysiological consequences of such GOF mutations in the heart. Methods: We generated transgenic mice (Kir6.1-GOF) expressing ATP-insensitive Kir6.1[G343D] subunits under -myosin heavy chain (-MHC) promoter control, to target gene expression specifically in cardiomyocytes, and carried out patch-clamp experiments on isolated ventricular myocytes, invasive electrophysiology on anesthetized mice. Results: In Kir6.1-GOF ventricular myocytes, KATP channels show decreased ATP sensitivity, but there is no significant change in current density. Ambulatory ECG recordings on Kir6.1-GOF mice reveal AV nodal conduction abnormalities and junctional rhythm. Invasive electrophysiological analyses reveal slowing of conduction and conduction failure through the AV node, but no increase in susceptibility to atrial or ventricular ectopic activity. Surface electrocardiograms recorded from CS patients also demonstrate first degree AV block, and fascicular block. Conclusions: The primary electrophysiological consequence of cardiac KATP GOF is on the conduction system, particularly the AV node, resulting in conduction abnormalities in CS patients, who carry KATP GOF mutations.
    Heart Rhythm 06/2015; DOI:10.1016/j.hrthm.2015.06.042

  • Heart Rhythm 05/2015;
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    ABSTRACT: Circular electroporation ablation is a novel ablation modality for electrical pulmonary vein isolation. With a single 200 joules application, deep circular myocardial lesions can be created. However, acute and chronic effects of this energy source on phrenic nerve (PN) function are unknown. Analysis of nerve vulnerability to electroporation ablation in a porcine model. In 20 animals (60-75 kg), the course of the right PN was pace-mapped inside the superior caval vein (SCV). Thereafter, a single 200 Joules circular electroporation ablation was performed via a multipolar circular catheter in firm contact with the inner SCV wall. In 19 of 20 animals, the PN could be captured along an estimated 6-8 cm trajectory above the right atrial contour. Directly after the application, the PN could be captured above the ablation level in 17 of 19 animals and after maximally 30 minutes in all. Fifteen animals were restudied after 3 to 13 weeks and PN functionality was unaffected in all. Histological analysis in 5 animals in which the application had been delivered in the muscular sleeve just above the right atrium showed a transmural circular lesion. However, no lesion was found in the other animals in which the application had been delivered in the fibrous section more cranial in the SCV. Electroporation ablation at an energy level that can create deep myocardial lesions may spare the targeted right PN. These animal data suggest that electroporation can be a safe ablation modality in the vicinity of the right PN. Copyright © 2015. Published by Elsevier Inc.
    Heart Rhythm 05/2015; 12(8). DOI:10.1016/j.hrthm.2015.05.012

  • Heart Rhythm 05/2015; 12(5).

  • Heart Rhythm 05/2015; 12(5):S112.
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    ABSTRACT: BACKGROUND The benefits ofimplantablecardioverter- defibrillators (ICDs)havebeenwelldemonstratedinmanyclinical trials, andICDshocksforventriculartachyarrhythmiassavelives. However, inappropriateandunnecessaryshockdeliveryremainsa significant clinicalissuewithconsiderableconsequencesfor patients andthehealthcaresystem. OBJECTIVE The purposeofthePainFreeSmartShockTechnology (SST) studywastoinvestigatenew-generationICDstoreduce inappropriate andunnecessaryshocksthroughnoveldiscrimination algorithms withmodernprogrammingstrategies. METHODS This prospective,multicenterclinicaltrialenrolled2790 patients withapprovedindicationforICDimplantation(79%male, mean age65years;69%primarypreventionindication,27%single- chamber ICD,33%replacementorupgrade).Patientswerefollowed for aminimumof12months,andmeanfollow-upwas22months. The primaryend-pointofthestudywasthepercentageofpatients remaining freeofinappropriateshocksat1yearpostimplant, analyzed separatelyfordual/triple-chamberICDs(N ¼ 2019) and single-chamber ICDs(N ¼ 751). RESULTS Theinappropriateshockrateat1yearwas1.5%for patients withdual/triple-chamber ICDsand2.5%forpatientswith single-chamberdevices.Twoyearspostimplant,theinappropriate shockratewas2.8%forpatientswithdual-/triplechamberICDsand 3.7% forthosewithsingle-chamberICDs.Themostcommoncauseof an inappropriateshockinbothgroupswasatrial fibrillation or flutter. CONCLUSION In alargepatientcohortreceivingICDsforprimary or secondaryprevention,theadoptionofnovelenhanceddetection algorithms inconjunctionwithroutineimplementationofmodern programming strategiesledtoaverylowinappropriateshockrate. KEYWORDS Implantable cardioverter-defibrillator; Cardiac resynchronization therapy;Heartfailure;Atrial fibrillation; Inappropriate shock
    Heart Rhythm 05/2015; 12(5):926-36. DOI:10.1016/j.hrthm.2015.01.017.
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    ABSTRACT: BACKGROUND Postablation atrial fibrillation recurrence is positively associated with the extent of preexisting left atrial (LA) late gadolinium enhancement (LGE) on magnetic resonance imaging (MRI), but negatively associated with the extent of postablation LGE regardless of proximity to the pulmonary vein antra. The characteristics of pre- vs postablation LA LGE may provide insight into this seeming paradox and inform future strategies for ablation. OBJECTIVE The purpose of this study was to define the characteristics of preexisting vs ablation-induced LA LGE. METHODS LGE-MRI was prospectively performed before and >= 3 months after initial ablation in 20 patients. The intracardiac locations of ablation points were coregistered with the corresponding sites on axial planes of postablation LGE-MRI. The image intensity ratio (IIR), defined as the LA myocardial MRI signal intensity divided by the mean LA blood pool intensity, and LA myocardial wall thickness were calculated on pre- and postablation images. RESULTS Imaging data from 409 pairs of pre- and postablation axial LGE-MRI planes and 6961 pairs of pre- and postablation image sectors were analyzed. Ablation-induced LGE revealed a higher IIR, suggesting greater contrast uptake and denser fibrosis, than did preexisting LGE (1.25 +/- 0.25 vs 1.14 +/- 0.15; P < .001). In addition, ablation-induced LGE regions had thinner LA myocardium (2.10 +/- 0.67 mm vs 2.37 +/- 0.74 mm; P < .001). CONCLUSION Regions with ablation-induced LGE exhibit increased contrast uptake, likely signifying higher scar density, and thinner myocardium as compared with regions with preexisting LGE. Future studies examining the association of postablation LGE intensity and nonuniformity with ablation success are warranted and may inform strategies to optimize ablation outcome.
    Heart Rhythm 04/2015; 12(4):668-672. DOI:10.1016/j.hrthm.20l4.12021

  • Heart Rhythm 03/2015; 12(3). DOI:10.1016/j.hrthm.2014.10.025