Heart Rhythm (HEART RHYTHM )
Heart Rhythm is a unique journal that integrates the entire cardiac electrophysiology (EP) community from basic to clinical academic researchers, to private practitioners, engineers, allied professionals, industry, and trainees, all of whom are vital and interdependent members of our EP community. The Journal addresses a broad range of topics that affect our EP world. Our major focus is on original research and therapy of heart rhythm disorders, including mechanisms and electrophysiology, both clinical and experimental, genetics, ablation, devices, drugs, and surgery. Other sections include Contemporary and Historical Reviews, unique Case Reports, Viewpoints, Cell to Bedside, Hands On, Featured Arrhythmias, Images with videos viewable on the Internet, Pacing/ICD Problems, Creative Concepts, Humanism in Medicine, EP News, Editorial Commentaries, Basic/Clinical Implications, Historical Vignettes, and Ten Questions for Allied Professionals. As the Official Journal of the Heart Rhythm Society and the Cardiac Electrophysiology Society, we also publish the Plenary address and the Douglas P. Zipes Lecture given at the annual Scientific Sessions of the Heart Rhythm Society, as well as the Gordon K. Moe Lecture presented at the annual Cardiac Electrophysiology Society meeting.
- Impact factor5.05Show impact factor historyHide impact factor history
- 5-year impact4.72
- Cited half-life3.60
- Immediacy index2.09
- Article influence1.79
- WebsiteHeart Rhythm website
- Other titlesHeart rhythm
- Material typePeriodical, Internet resource
- Document typeJournal / Magazine / Newspaper, Internet Resource
- Author can archive a pre-print version
- Author can archive a post-print version
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- Pre-print can not be deposited for The Lancet
- Classification green
Publications in this journal
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ABSTRACT: Background Our group has previously shown that colchicine treatment is associated with decreased early recurrence rate after ablation for atrial fibrillation (AF). Objective The purpose of this study was to test the mid-term efficacy of colchicine in reducing AF recurrences after a single procedure of pulmonary vein isolation in patients with paroxysmal AF. Assessment of quality of life (QoL) changes was a secondary objective. Methods Patients with paroxysmal AF, slated for ablation, were randomized to a 3-month course of colchicine, 0.5 mg twice daily, or placebo and followed for a median of 15 months (with a 3-month blanking period). QoL was assessed with a general purpose health-related QoL tool (26-item World Health Organization QoL questionnaire) at baseline, 3 and 12 months. Results 23 randomized patients underwent ablation and 206 patients were available for analysis (age 62.2±5.8 years, 144 male). AF recurrence rate in the colchicine group was 31.1% (32 of 103) versus 49.5% (51 of 103) in the control group (p=0.010), translated in a relative risk reduction of 37% (odds ratio 0.46; 95% confidence interval 0.26-0.81). The number-needed-to-treat was 6 (95% confidence interval 3.2-19.8). Physical domain QoL scores at 12 months were 63.6±13.8 in the colchicine group and 52.5±18.1 in controls, while psychological domain scores were 56.1±13.7 versus 44.7±17.3 (p<0.001, for both). Conclusion Colchicine treatment after pulmonary vein isolation for paroxysmal AF is associated with lower AF recurrence rate after a single procedure. This reduction is accompanied by corresponding improvements in physical- and psychological-health-related QoL scores.Heart Rhythm 02/2014;
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ABSTRACT: Background Suggested by the authors new theoretical model of hemodynamics based on mathematical calculations of the formation of the special conditions of blood flow in vessels, shows the existence of the blood flow pattern, supported by a mechanism of hemodynamics self-regulation. It is reflected in the cardiac cycle phase structure. Using the analysis of the electrocardiosignal phase characteristics changes, it is possible to accurately trace the compensatory mechanism of substitution of the various segments of the cardiovascular system functions. This defines a fundamentally new approach in the cardiovascular system diagnostics. Methods The objective is to evaluate the efficiency of the new theoretical model of cardiovascular system hemodynamics, allowing to measure the basic hemodynamics parameters with the indirect method, and also to research on the compensation mechanism of hemodynamics self-regulation. To obtain the measuring signal, which reflects the entire cardiac cycle phase structure, the new original derivation is used, it is called the ECG of the ascending aorta. It records all the 10 phases of the cardiac cycle that can not be obtained with standard methods of recording. By measuring the duration of the phases in linear quantities, and substituting it into the Poyedintsev – Voronova equation of hemodynamics, the volumetric values are calculated. The 7 phase volumes of blood are calculated in such a way. The next step is the cardiac muscle contraction function evaluation in each phase of the ECG. Although this procedure is considered to be a qualitative evaluation, but it is based on the quantitative measurement of the ECG amplitude in each phase, which is equivalent to the cardiac muscle contraction amplitude. It characterizes the compensatory mechanism of hemodynamics self-regulation. Results Blood phase volumes measurement researches allowed us to understand the mechanisms of hemodynamics maintenance and to classify the range of cardiac functions changes from norm to extreme pathology. Conclusions The method can evaluate the age-related changes in hemodynamics. It also effectively evaluates the effect of physical activity on the healthy heart. The authors succeeded in revealing the criteria for sudden cardiac death prediction.Heart Rhythm 11/2012; 9(11):1909-1910.
Article: Bessière F, Chevalier P. Pulmonary vein hematoma after atrial fibrillationcryoablation: A new complication. Heart Rhythm. 2012 May 1. [Epub ahead of print]PubMed PMID: 22561845.2: Bessière F, Chevalier P. [Intracardiac conduction disturbances]. Rev Prat.2012 Feb;62(2):269-73. Review. French. PubMed PMID: 22408881.3: Chevalier P, Timour Q, Morel E, Bui-Xuan B. Chronic Oral Amiodarone but notDronedarone Therapy Increases Ventricular Defibrillation Threshold During AcuteMyocardial Ischemia in a CloHeart Rhythm 05/2012;
- Heart Rhythm 01/2010; 7:1365.
- Heart Rhythm 06/2008; 5(6).
- Heart Rhythm 05/2008;
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ABSTRACT: Temporal variation in complex fractionated atrial electrograms (CFAEs) exists during atrial fibrillation (AF). This study sought to quantify the variation in CFAEs using a fractionation interval (FI) algorithm and to define the shortest optimal recording duration required to consistently characterize the magnitude of the fractionation. Twenty-seven patients undergoing AF mapping in the left atrium were studied. The FI and frequency analysis were performed at each mapped site for recording durations of 1 to 8 seconds. The magnitude of the fractionation was quantified by the FI algorithm, which calculated the mean interval between multiple, discrete deflections during AF. The results from each duration were statistically compared with the maximal-duration recording, as a standard. The FI values were compared with the dominant frequency values obtained from the associated frequency spectra. The FIs obtained from recording durations between 5 and 8 seconds had a smaller variation in the FI (P < .05) and, for those sites with a FI < 50 ms, the fractionation was typically continuous. The fast-Fourier Transform spectra obtained from the CFAE sites with recording durations of >5 seconds harbored higher dominant frequency values than those with shorter recording durations (8.1 +/- 2.5 Hz vs. 6.8 +/- 0.98 Hz, P < .05). The CFAE sites with continuous fractionation were located within the pulmonary veins and their ostia in 77% of patients with paroxysmal AF, and in only 29% of patients with nonparoxysmal AF (P < .05). The assessment of fractionated electrograms requires a recording duration of > or =5 seconds at each site to obtain a consistent fractionation. Sites with the shortest FIs consistently identified sites with the fastest electrogram activity throughout the entire left atrium and pulmonary veins.Heart Rhythm 04/2008; 5(3):406-12.
- Heart Rhythm 04/2008; 5(3):460-1.
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ABSTRACT: Defibrillation threshold (DFT) testing has traditionally been a routine part of implantable cardioverter-defibrillator (ICD) implantation, despite a lack of compelling evidence that it predicts or improves outcomes. In the past, when devices were much less reliable, DFT testing seemed prudent; however, modern ICD systems have such a high rate of successful defibrillation that many electrophysiologists now question whether DFT testing is still worthwhile, particularly since DFT testing may now be the highest acute risk component of ICD implantation. The purpose of this study was to systematically document complications directly attributable to intraoperative DFT testing. We obtained data on DFT-related complications from all 21 adult ICD implant centers in Canada, covering the period from January 1, 2000, to September 30, 2006. There were a total of 19,067 ICD implants in Canada during the study period. There were three DFT testing-related deaths, five DFT testing-related strokes, and 27 episodes that required prolonged resuscitation. Two patients had significant clinical sequelae after prolonged resuscitation. The risk of severe complications from intraoperative DFT testing appears small, even allowing for the underestimation of its true rate with the current study methodology. These slight but measurable risks must be considered when assessing the risk-benefit ratio of the procedure. Additional data from ongoing prospective ICD registries and/or clinical trials are required.Heart Rhythm 04/2008; 5(3):387-90.
- Heart Rhythm 04/2008; 5(3):366.
- Heart Rhythm 04/2008; 5(3):483-6.
- Heart Rhythm 04/2008; 5(3):479-82.
- Heart Rhythm 04/2008; 5(3):472-4.
- Heart Rhythm 04/2008; 5(3):498-9.
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ABSTRACT: Conduction block across the left mitral isthmus (LMI) seems more challenging to achieve and validate compared with the cavotricuspid isthmus (CTI). This study sought to investigate the relationship between peritricuspid and perimitral circuit times in the same patient and to compare the difficulty in achieving the CTI and LMI linear lesions. We retrospectively studied 122 consecutive patients (46 paroxysmal and 76 persistent) admitted for atrial fibrillation ablation or subsequent atrial macroreentry who underwent both CTI and LMI ablation. The peritricuspid and perimitral conduction times were measured after validation of bidirectional block across their respective line by pacing from the septal side of the CTI or LMI and recording of the second late potential on the line of block. Atrial dimensions were measured by standard transthoracic echocardiographic techniques. The mean peritricuspid and perimitral times were 180 +/- 35 ms (range 120 to 300) and 189 +/- 42 ms (range 120 to 322), respectively, with a mean difference of 7 +/- 32 ms (-70 to 95). The correlation between both circuit times was highly significant (r = 0.621, P < .001). In 84 patients (68%), the perimitral time was within 30 ms of the peritricuspid time. In the remaining patients, only 12 (10% of the total patients) had a shorter perimitral time compared with peritricuspid time. Radiofrequency energy delivered was significantly longer for LMI (15 +/- 7 min [range 7 to 33]) compared with CTI (7 +/- 4 min [range 3 to 17]) (P = .005). The peritricuspid and perimitral circuit times are strongly correlated. In 90% of patients, the perimitral conduction time is within 30 ms or longer than the peritricuspid time. In addition, both circuit times are always > or = than 120 ms. Compared with the left mitral isthmus line, the CTI line is significantly easier to perform.Heart Rhythm 04/2008; 5(3):400-5.
- Heart Rhythm 04/2008; 5(3):375-7.
- Heart Rhythm 04/2008; 5(3):489-90.
- Heart Rhythm 04/2008; 5(3):502-3; author reply 503-4.
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