Annual Review of Nutrition Journal Impact Factor & Information

Publisher: Annual Reviews

Current impact factor: 8.36

Impact Factor Rankings

2015 Impact Factor Available summer 2016
2014 Impact Factor 8.359
2013 Impact Factor 10.459
2012 Impact Factor 9.158
2011 Impact Factor 9.447
2010 Impact Factor 7.878
2009 Impact Factor 8.783
2008 Impact Factor 8.205
2007 Impact Factor 8.689
2006 Impact Factor 10.449
2005 Impact Factor 8.605
2004 Impact Factor 11.075
2003 Impact Factor 9.326
2002 Impact Factor 7.915
2001 Impact Factor 7.784
2000 Impact Factor 7.071
1999 Impact Factor 5.523
1998 Impact Factor 5.13
1997 Impact Factor 5.857

Impact factor over time

Impact factor

Additional details

5-year impact 9.66
Cited half-life >10.0
Immediacy index 0.50
Eigenfactor 0.00
Article influence 3.31
Website Annual Review of Nutrition website
Other titles Annual review of nutrition
ISSN 1545-4312
OCLC 6307740
Material type Internet resource
Document type Journal / Magazine / Newspaper, Internet Resource

Publisher details

Annual Reviews

  • Pre-print
    • Author can archive a pre-print version
  • Post-print
    • Author cannot archive a post-print version
  • Conditions
    • Must prominently state near the title of the preprint version that the article has been accepted for publication by Annual Reviews in a revised form
    • Authors may place their ePrint URL (free access to article) on one of author's personal website and one institutional repository only
    • Publisher copyright and source must be acknowledged
    • Must link to publisher version
    • Publisher last contacted on 03/09/2014
    • Publisher last reviewed on 10/08/2015
  • Classification

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: It is well known that the amount and type of ingested fat impacts the development of obesity and metabolic diseases, but the potential for beneficial effects from fat has received less attention. It is becoming clear that the composition of the individual fatty acids in diet is important. Besides acting as precursors of potent signaling molecules, dietary fatty acids act directly on intracellular and cell surface receptors. The free fatty acid receptor 4 (FFA4, previously GPR120) is linked to the regulation of body weight, inflammation, and insulin resistance and represents a potential target for the treatment of metabolic disorders, including type 2 diabetes and obesity. In this review, we discuss the various types of dietary fatty acids, the link between FFA4 and metabolic diseases, the potential effects of the individual fatty acids on health, and the ability of fatty acids to activate FFA4. We also discuss the possibility of dietary schemes that implement activation of FFA4.
    Annual Review of Nutrition 07/2015; 35(1):239-263. DOI:10.1146/annurev-nutr-071714-034410
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    ABSTRACT: Vitamin E modulates the activity of several signal transduction enzymes with consequent alterations of gene expression. At the molecular level, vitamin E may directly bind to these enzymes and compete with their substrates, or it may change their activity by redox regulation. The translocation of several of these enzymes to the plasma membrane is regulated by vitamin E, suggesting the modulation of protein-membrane interactions as a common mechanism for vitamin E action. Enzyme-membrane interactions can be affected by vitamin E by interference with binding to specific membrane lipids or by altering cellular structures such as membrane microdomains (lipid rafts). Moreover, competition by vitamin E for common binding sites within lipid transport proteins may alter the traffic of lipid mediators and thus affect their signaling and enzymatic conversion. In this review, the main effects of vitamin E on enzymes involved in signal transduction are summarized and possible molecular mechanisms leading to enzyme modulation are evaluated.
    Annual Review of Nutrition 07/2015; 35(1):135-173. DOI:10.1146/annurev-nutr-071714-034347
  • Source
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    ABSTRACT: As Erwin Chargaff observed, "Scientific autobiography belongs to a most awkward literary genre," and mine is no exception. In reviewing my scientific life, I contrast the nutritional influences that would have existed had I been born 100 or 200 years earlier than I actually was. With this background, I trace the influences on my formative years in science beginning in high school and ending as a postdoctoral fellow in Professor E.B. Astwood's laboratory, when my directional sails were set and obesity was the compass heading. With this heading, the need for organized national and international meetings on obesity and the need for a scientific journal dealing with obesity as its subject matter became evident and occupied considerable energy over the next 30 years. The next section of this memoir traces the wanderings of an itinerant academic who moved from Boston to Los Angeles and finally to Baton Rouge. The influence of Sir William Osler's idea that there is a time for education, a time for scholarship, a time for teaching, and time to retire has always been a guide to allocating time ever since I was an intern at Johns Hopkins Hospital. It was in Baton Rouge that the final phase began: I agreed to become the first full-time executive director of the Pennington Biomedical Research Center, a decision that changed my life. The article ends with a quotation from Tennessee Williams that reflects the theater, which has given me so much pleasure over the years: "There is a time for departure even when there's no certain place to go."
    Annual Review of Nutrition 07/2015; 35(1):1-31. DOI:10.1146/annurev-nutr-121214-104412
  • [Show abstract] [Hide abstract]
    ABSTRACT: Diet is a leading modifiable risk factor for chronic disease, but it remains difficult to measure accurately due to the error and bias inherent in selfreported methods of diet assessment. Consequently, there is a pressing need for more objective biomarkers of diet for use in health research. The stable isotope ratios of light elements are a promising set of candidate biomarkers because they vary naturally and reproducibly among foods, and those variations are captured in molecules and tissues with high fidelity. Recent studies have identified valid isotopic measures of short- and long-term sugar intake, meat intake, and fish intake in specific populations. These studies provide a strong foundation for validating stable isotopic biomarkers in the general US population. Approaches to improve specificity for specific foods are needed; for example, by modeling intake using multiple stable isotope ratios or by isolating and measuring specific molecules linked to foods of interest. Expected final online publication date for the Annual Review of Nutrition Volume 35 is July 17, 2015. Please see for revised estimates.
    Annual Review of Nutrition 05/2015; 35(1). DOI:10.1146/annurev-nutr-071714-034511
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    ABSTRACT: The understanding of manganese (Mn) biology, in particular its cellular regulation and role in neurological disease, is an area of expanding interest. Mn is an essential micronutrient that is required for the activity of a diverse set of enzymatic proteins (e.g., arginase and glutamine synthase). Although necessary for life, Mn is toxic in excess. Thus, maintaining appropriate levels of intracellular Mn is critical. Unlike other essential metals, cell-level homeostatic mechanisms of Mn have not been identified. In this review, we discuss common forms of Mn exposure, absorption, and transport via regulated uptake/ exchange at the gut and blood-brain barrier and via biliary excretion. We present the current understanding of cellular uptake and efflux as well as subcellular storage and transport of Mn. In addition, we highlight the Mndependent and Mn-responsive pathways implicated in the growing evidence of its role in Parkinson's disease and Huntington's disease. We conclude with suggestions for future focuses of Mn health-related research. Expected final online publication date for the Annual Review of Nutrition Volume 35 is July 17, 2015. Please see for revised estimates.
    Annual Review of Nutrition 05/2015; 35(1). DOI:10.1146/annurev-nutr-071714-034419
  • [Show abstract] [Hide abstract]
    ABSTRACT: Selenium is regulated in the body to maintain vital selenoproteins and to avoid toxicity. When selenium is limiting, cells utilize it to synthesize the selenoproteins most important to them, creating a selenoprotein hierarchy in the cell. The liver is the central organ for selenium regulation and produces excretory selenium forms to regulate whole-body selenium. It responds to selenium deficiency by curtailing excretion and secreting selenoprotein P (Sepp1) into the plasma at the expense of its intracellular selenoproteins. Plasma Sepp1 is distributed to tissues in relation to their expression of the Sepp1 receptor apolipoprotein E receptor-2, creating a tissue selenium hierarchy. N-terminal Sepp1 forms are taken up in the renal proximal tubule by another receptor, megalin. Thus, the regulated whole-body pool of selenium is shifted to needy cells and then to vital selenoproteins in them to supply selenium where it is needed, creating a whole-body selenoprotein hierarchy. Expected final online publication date for the Annual Review of Nutrition Volume 35 is July 17, 2015. Please see for revised estimates.
    Annual Review of Nutrition 05/2015; 35(1). DOI:10.1146/annurev-nutr-071714-034250
  • [Show abstract] [Hide abstract]
    ABSTRACT: Obesity is a chronic and complex medical condition associated with a large number of complications affecting most organs and systems through multiple pathways. Strategies for weight management include behavioral, pharmacological, and surgical interventions, all of which can result in a reduction in obesity-related comorbidities and improvements in quality of life. However, subsequent weight regain often reduces the durability of these improvements. The objective of this article is to review evidence supporting the long-term effects of intentional weight loss on morbidity, mortality, quality of life, and health-care cost. Overall, considerable evidence suggests that intentional weight loss is associated with clinically relevant benefits for the majority of obesity-related comorbidities. However, the degree of weight loss that must be achieved and sustained to reap these benefits varies widely between comorbidities. Expected final online publication date for the Annual Review of Nutrition Volume 35 is July 17, 2015. Please see for revised estimates.
    Annual Review of Nutrition 05/2015; 35(1-1). DOI:10.1146/annurev-nutr-071714-034434
  • [Show abstract] [Hide abstract]
    ABSTRACT: Coenzyme Q (CoQ) is an essential lipid of cells present in all cellular compartments. The functions of CoQ in mitochondrial respiration and as an antioxidant are established, although the lipid likely has additional, presently unknown, roles. While the therapeutic utility of CoQ10 supplements is recognized in the rare cases of primary CoQ10 deficiencies, a potential role for CoQ10 supplements in cardiovascular disease, particularly heart failure, has also been studied for over 40 years. This review summarizes our current knowledge in these areas derived from animal studies and human trials. Current evidence for a benefit of CoQ10 supplements in diseases other than primary CoQ10 deficiencies is insufficient. Expected final online publication date for the Annual Review of Nutrition Volume 35 is July 17, 2015. Please see for revised estimates.
    Annual Review of Nutrition 05/2015; 35(1). DOI:10.1146/annurev-nutr-071714-034258
  • [Show abstract] [Hide abstract]
    ABSTRACT: The Mediterranean dietary pattern has been linked with reduced cardiovascular disease incidence and mortality. Components of the Mediterranean diet associated with better cardiovascular health include low consumption of meat and meat products, moderate consumption of ethanol (mostly from wine), and high consumption of vegetables, fruits, nuts, legumes, fish, and olive oil. Increasing evidence indicates that the synergy among these components results in beneficial changes in intermediate pathways of cardiometabolic risk, such as lipids, insulin sensitivity, oxidative stress, inflammation, and vasoreactivity. As a result, consumption of a Mediterranean dietary pattern favorably affects numerous cardiovascular disease risk factors, such as dyslipidemia, hypertension, metabolic syndrome, and diabetes. Moreover, strong evidence links this dietary pattern with reduced cardiovascular disease incidence, reoccurrence, and mortality. This review evaluates the current evidence behind the cardioprotective effects of a Mediterranean dietary pattern. Expected final online publication date for the Annual Review of Nutrition Volume 35 is July 17, 2015. Please see for revised estimates.
    Annual Review of Nutrition 05/2015; 35(1). DOI:10.1146/annurev-nutr-011215-025104
  • [Show abstract] [Hide abstract]
    ABSTRACT: Itaconic acid is well known as a precursor for polymer synthesis and has been involved in industrial processes for decades. In a recent surprising discovery, itaconic acid was found to play a role as an immune-supportive metabolite in mammalian immune cells, where it is synthesized as an antimicrobial compound from the citric acid cycle intermediate cis-aconitic acid. Although the immune-responsive gene 1 protein (IRG1) has been associated to immune response without a mechanistic function, the critical link to itaconic acid production through an enzymatic function of this protein was only recently revealed. In this review, we highlight the history of itaconic acid as an industrial and antimicrobial compound, starting with its biotechnological synthesis and ending with its antimicrobial function in mammalian immune cells. Expected final online publication date for the Annual Review of Nutrition Volume 35 is July 17, 2015. Please see for revised estimates.
    Annual Review of Nutrition 05/2015; 35(1). DOI:10.1146/annurev-nutr-071714-034243
  • [Show abstract] [Hide abstract]
    ABSTRACT: Emerging evidence suggests that ascorbate, the dominant form of vitamin C under physiological pH conditions, influences activity of the genome via regulating epigenomic processes. Ascorbate serves as a cofactor for Ten-eleven translocation (TET) dioxygenases that catalyze the oxidation of 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC), and further to 5-formylcytosine (5fC) and to 5-carboxylcytosine (5caC), which are ultimately replaced by unmodified cytosine. The Jumonji C (JmjC)-domaincontaining histone demethylases also require ascorbate as a cofactor for histone demethylation. Thus, by primarily participating in the demethylation of both DNA and histones, ascorbate appears to be a mediator of the interface between the genome and environment. Furthermore, redox status has a profound impact on the bioavailability of ascorbate in the nucleus. In order to bridge the gap between redox biology and genomics, we suggest an interdisciplinary research field that can be termed redox genomics to study dynamic redox processes in health and diseases. This review examines the evidence and potential molecular mechanism of ascorbate in the demethylation of the genome, and it highlights potential epigenetic roles of ascorbate in various diseases. Expected final online publication date for the Annual Review of Nutrition Volume 35 is July 17, 2015. Please see for revised estimates.
    Annual Review of Nutrition 05/2015; 35(1). DOI:10.1146/annurev-nutr-071714-034228