American Journal of Human Biology (Am J Hum Biol )

Publisher: Human Biology Council, John Wiley and Sons


The American Journal of Human Biology is a peer-reviewed internationally circulated journal that publishes reports of original research theoretical articles and timely reviews and brief communications in the interdisciplinary field of human biology. The Journal serves as a forum for scientists and health professionals who share common interests in understanding individual and population variation in health and disease. As the official journal of the HUMAN BIOLOGY ASSOCIATION the Journal also publishes abstracts of research presented at its annual scientific meeting. Reviews of books and other publications relevant to human biology are also regularly published. The Journal seeks scholarly manuscripts that address all aspects of the discipline of human biology. The transdisciplinary areas covered by human biology include but are not limited to epidemiology genetic variation population biology and demography physiology anatomy nutrition growth and aging performance and physical fitness exercise science ecology and evolution along with their interactions. The Journal publishes basic applied and methodologically oriented research from all areas including measurement analytical techniques and strategies and computer applications in human biology. Like many other biologically oriented disciplines the field of human biology has undergone considerable growth and diversification in recent years and the expansion of the aims and scope of the Journal is a reflection of this growth and membership diversification. The Journal is committed to prompt review and priority publication is given to manuscripts with novel or timely findings and to manuscripts of unusual interest.

Impact factor 1.93

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    American Journal of Human Biology website
  • Other titles
    American journal of human biology (Online), American journal of human biology
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    Document, Periodical, Internet resource
  • Document type
    Internet Resource, Computer File, Journal / Magazine / Newspaper

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John Wiley and Sons

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    • Author can archive a pre-print version
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    • See Wiley-Blackwell entry for articles after February 2007
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    • Articles in some journals can be made Open Access on payment of additional charge
    • 'John Wiley and Sons' is an imprint of 'Wiley'
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    ​ green

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: In 1828, between 8,000 and 15,000 Indians from the Jesuit Missions were brought to Uruguay. There, they were settled in a village, presently named Bella Unión, in the northwest corner of the country. According to historic sources, the Indians abandoned the settlement shortly thereafter, with the village subsequently repopulated by "criollos" and immigrants from abroad. As a first approach to reconstruct the genetic history of the population, data about the living population genetic structure will be used. Based on the analysis of the maternal lineages of the inhabitants of Bella Unión, and of those from two nearby villages, we expect to partially answer what happened with the first and subsequent inhabitants. We analyzed the maternal lineages of the present inhabitants of Bella Unión and neighboring localities through the sequencing of the mitochondrial DNA control region. A total of 64.3%, 5.7%, and 30% of the mtDNAs were of Native, African, and West Eurasian origin, respectively. These figures are quite similar to that of the population of Tacuarembó, which is located in northeastern Uruguay. The four main Native American founding haplogroups were detected, with B2 being the most frequent, while some rare subhaplogroups (B2h, C1b2, D1f1) were also found. When compared with other Native American sequences, near- matches most consistently pointed to an Amazonian Indian origin which, when considered with historical evidence, suggested a probable Guaraní-Missionary-related origin. The data support the existence of a relationship between the historic and present inhabitants of the extreme northwest Uruguay, with a strong contribution of Native Americans to the mitochondrial DNA diversity observed there. Am. J. Hum. Biol., 2014. © 2014 Wiley Periodicals, Inc. © 2014 Wiley Periodicals, Inc.
    American Journal of Human Biology 12/2014;
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    ABSTRACT: This study aims to validate a modified dried blood spot (DBS)-based glycosylated hemoglobin (HbA1c) assay protocol, after a pretest in India showed poor correlation between the original DBS-based protocol and venous results. The original protocol was tested on different chemistry analyzers and then simplified at the University of Washington (UW). A second pretest was conducted in India to validate the modified assay protocol, using 44 quality control specimens. Data from UW indicated that, using the original protocol, the correlation coefficients between DBS and venous results were above 0.98 on both Bio-Rad and Olympus chemistry analyzers. The protocol worked equally well on filter paper, with or without pre-treatment, and when the recommended amount of blood spot material, or less, was used. A second pretest of the modified protocol confirmed that DBS-based levels from both Olympus and Roche chemistry analyzers were well correlated with DBS results from UW (correlation coefficients were above 0.96), as well as with venous values (correlation coefficients were above 0.94). The DBS-based HbA1c values are highly correlated with venous results. The pre-treatment of filter paper does not appear to be necessary. The poor results from the first pretest are probably due to factors unrelated to the protocol, such as problems with the chemistry analyzer or assay reagents. Am. J. Hum. Biol., 2014. © 2014 Wiley Periodicals, Inc. © 2014 Wiley Periodicals, Inc.
    American Journal of Human Biology 12/2014;
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    ABSTRACT: Objective Glutathione S-transferase (GST) variants have been widely investigated to better understand their role in several pathologic conditions. To our knowledge, no data about these genetic polymorphisms within the Turkish population are currently available. The aim of this study was to analyze GSTM1 positive/null, GSTT1 positive/null, GSTP1*I105V (rs1695), and GSTP1*A114V (rs1138272) variants in the general Turkish population, to provide information about its genetic diversity, and predisposition to GST-related diseases.Methods Genotyping was performed in 500 Turkish individuals using the Sequenom MassARRAY platform. A comparative analysis was executed using the data from the HapMap and Human Genome Diversity Projects (HGDP). Sequence variation was deeply explored using the Phase 1 data of the 1,000 Genomes Project.ResultsThe variability of GSTM1, GSTT1, and GSTP1 polymorphisms in the Turkish population was similar to that observed in Central Asian, European, and Middle Eastern populations. The high linkage disequilibrium between GSTP1*I105V and GSTP1*A114V in these populations may have a confounding effect on GSTP1 genetic association studies. In analyzing GSTM1, GSTT1, and GSTP1 sequence variation, we observed other common functional variants that may be candidates for associated studies of diseases related to GST genes (e.g., cancer, cardiovascular disease, and allergy).Conclusions This study provides novel data about GSTM1 positive/null, GSTT1 positive/null, GSTP1*I105V, and GSTP1*A114V variants in the Turkish population, and other functional variants that may affect GSTM1, GSTT1, and GSTP1 functions among worldwide populations. This information can assist in the design of future genetic association studies investigating oxidative stress-related diseases. Am. J. Hum. Biol., 2014. © 2014 Wiley Periodicals, Inc.
    American Journal of Human Biology 12/2014;
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    ABSTRACT: The Accompong Town Maroons are descendants of enslaved Africans who successfully waged war against British colonial rule and established an independent community in western Jamaica. There are discrepancies regarding Accompong Town Maroon ancestry with some scholars noting ancestry from both Africans and Taínos, Jamaica's indigenous population, while other scholars only acknowledge African ancestry. We considered the mitochondrial lineages of contemporary Accompong Town Maroons to address the question of ancestral origins.
    American Journal of Human Biology 11/2014;
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    ABSTRACT: Contemporary human biology research employs a unique skillset for biocultural analysis. This skillset is highly appropriate for the study of health disparities because disparities result from the interaction of social and biological factors over one or more generations. Health disparities research almost always involves disadvantaged communities owing to the relationship between social position and health in stratified societies. Successful research with disadvantaged communities involves a specific approach, the community partnership model, which creates a relationship beneficial for researcher and community. Paramount is the need for trust between partners. With trust established, partners share research goals, agree on research methods and produce results of interest and importance to all partners. Results are shared with the community as they are developed; community partners also provide input on analyses and interpretation of findings. This article describes a partnership-based, 20 year relationship between community members of the Akwesasne Mohawk Nation and researchers at the University at Albany. As with many communities facing health disparity issues, research with Native Americans and indigenous peoples generally is inherently politicized. For Akwesasne, the contamination of their lands and waters is an environmental justice issue in which the community has faced unequal exposure to, and harm by environmental toxicants. As human biologists engage in more partnership-type research, it is important to understand the long term goals of the community and what is at stake so the research circle can be closed and 'helicopter' style research avoided. Am. J. Hum. Biol., 2014. © 2014 Wiley Periodicals, Inc.
    American Journal of Human Biology 11/2014;
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    ABSTRACT: Objective We investigated the impact of detailed body composition on aerobic fitness to determine whether regional components of fat mass have independent effects on VO2submax, and whether VO2submax and detailed body composition independently explain variation in REE.Methods71 healthy adults (80% female, 20% male, BMI 28.2–43.8 kg/m2) were investigated. Body composition was measured by the four-compartment model together with whole body magnetic resonance imaging (MRI) to assess high and low metabolic rate organs and regional fat depots. VO2submax was estimated at 75% of predicted maximum heart rate.ResultsThere was a strong association between VO2submax and FFM and all organ masses except for heart. Skeletal muscle mass accounted for 34.8% of the variance in VO2submax. In addition, subcutaneous adipose tissue (SAT) of extremities explained additional 14.4%. FFM and FM explained 71.3% of the variance in REE. Including the components of FFM and FM, the explained variance in REE increased by about 5.8%; skeletal muscle mass explained 70.0% of the variance in REE and kidney and liver masses explained additional 7.1%. VO2submax correlated with REE. Taking into account body composition, VO2submax did not add to the variance in REE.ConclusionFFM is a determinant of both VO2submax and REE. Modeling either REE or VO2submax from individual components of FFM, about 77.1% of variance in REE (by muscle, liver and kidneys mass) and 34.8% of variance in VO2submax (by skeletal muscle mass) could be explained. FM explained additional variance in REE, whereas SAT of extremities added to the variance in VO2submax only. Am. J. Hum. Biol., 2014. © 2014 Wiley Periodicals, Inc.
    American Journal of Human Biology 11/2014;
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    ABSTRACT: Objectives This study provides updated data on body composition in adult Spanish women.Methods We considered data, including height and weight, from a survey conducted on a total of 4,013 adult women between 2009 and 2010. A subgroup of 2,224 women completed a bioelectrical body impedance analysis of body composition using a Tanita Body Composition Analyzer (Model no. BF-418).ResultsTotal fat mass (FM) gradually increased between 18 and 74 years of age and decreased thereafter. FM increased in both legs between 65 and 74 years of age (5.69 ± 1.4 Kg and 5.66 ± 1.4 Kg for right and left legs, respectively) and decreased thereafter. FM in the right arm increased until 44 years of age (1.22 ± 2.6 Kg), decreased to 1.19 ± 0.5 Kg between 45 and 54 years of age, and increased to 1.54 ± 0.63 from 65 to 74 years of age. FM in the left arm increased constantly until it reached a peak of 1.63 ± 0.6 Kg between 65 and 74 years of age and decreased thereafter. FM increased in the trunk throughout life (peaks at 13.27±3.8 Kg) until subjects reached between 65 and 74 years of age. Fat free mass increased until 44 years of age (42.42 ± 4.17 Kg) and decreased thereafter. The prevalence of overweight/obesity significantly increased with age in the entire sample.Conclusions Our results indicate that age-related increases in weight were at least partially due to increased adiposity. Am. J. Hum. Biol., 2014. © 2014 Wiley Periodicals, Inc.
    American Journal of Human Biology 11/2014;
  • American Journal of Human Biology 11/2014;
  • American Journal of Human Biology 11/2014;
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    ABSTRACT: Objectives Human conception cohorts in gestation during stressful times reportedly yield lower ratios of male to female live births than do other conception cohorts. Much literature attributes this phenomenon to spontaneous abortion of less fit male fetuses. Controversy remains, however, as to whether stressful times make males fetuses less fit (“Shifting Distribution” of fitness) or whether male fetuses need greater fitness to avoid spontaneous abortion during stressful times (“Shifting Criterion” for survival).Methods Although research using gestational hCG as a signal of fetal fitness reports support for the latter mechanism, we believe an analytic error casts doubt on those findings. Here we offered an alternative test that corrects the error.Conclusion This more accurate test found similar results to those originally reported. Am. J. Hum. Biol., 2014. © 2014 The Authors American Journal of Human Biology Published by Wiley Periodicals, Inc.
    American Journal of Human Biology 11/2014;
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    ABSTRACT: Objectives Adult body mass (MB) empirically scales as height (Ht) squared (MB ∝ Ht2), but does regional body mass and body composition as a whole also scale as Ht2? This question is relevant to a wide range of biological topics, including interpretation of body mass index (BMI).Methods Dual-energy X-ray absorptiometry (DXA) was used to quantify regional body mass [head (MH), trunk, arms, and legs] and whole-body composition [fat, lean soft tissue (LST), and bone mineral content (BMC)] in non-Hispanic (NH) white, NH black, Mexican American, and Korean adults participating in the National Health and Nutrition Examination Survey (NHANES; n = 17,126) and Korean NHANES (n = 8,942). Regression models were developed to establish Ht scaling powers for each measured component with adjustments for age and adiposity.ResultsExploratory analyses revealed a consistent scaling pattern across men and women of the four population groups: regional mass powers, head (∼0.8–1) < arms and trunk (∼1.8–2.3) < legs (∼2.3–2.6); and body composition, LST (∼2.0–2.3) < BMC (∼2.1–2.4). Small sex and population differences in scaling powers were also observed. As body mass scaled uniformly across the eight sex and population groups as Ht∼2, tall and short subjects differed in body shape (e.g., MH/MB ∝ Ht−∼1) and composition.Conclusions Adult human body shape and relative composition are a function of body size as represented by stature, a finding that reveals a previously unrecognized phenotypic heterogeneity as defined by BMI. These observations provide new pathways for exploring mechanisms governing the interrelations between adult stature, body morphology, biomechanics, and metabolism. Am. J. Hum. Biol., 2014. © 2014 Wiley Periodicals, Inc.
    American Journal of Human Biology 11/2014;