Asian Pacific journal of cancer prevention: APJCP Impact Factor & Information

Publisher: Asian Pacific Organization for Cancer Prevention; International Association of Cancer Registries

Current impact factor: 2.51

Impact Factor Rankings

2015 Impact Factor Available summer 2016
2014 Impact Factor 2.514
2013 Impact Factor 1.5
2012 Impact Factor 1.271
2011 Impact Factor 0.659
2010 Impact Factor 1.24
2009 Impact Factor 1.108

Impact factor over time

Impact factor

Additional details

5-year impact 2.27
Cited half-life 2.20
Immediacy index 0.85
Eigenfactor 0.01
Article influence 0.24
Website Asian Pacific Journal of Cancer Prevention: APJCP website
Other titles Asian Pacific journal of cancer prevention (Online), APJCP
ISSN 1513-7368
OCLC 70240111
Material type Document, Internet resource
Document type Internet Resource, Computer File, Journal / Magazine / Newspaper

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: Cancer loci comprise heterogeneous cell populations with diverse cellular secretions. Therefore, disseminating cancer-specific or cancer-associated protein antigens from tissue lysates could only be marginally correct, if otherwise not validated against precise standards. In this study, 2DE proteomic profiles were examined from lysates of 13 lung-adenocarcinoma tissue samples and matched against the A549 cell line proteome. A549 matched-cancer-specific hits were analyzed and characterized by MALDI-TOF/MS. Comparative analysis identified a total of 13 protein spots with differential expression. These proteins were found to be involved in critical cellular functions regulating pyrimidine metabolism, pentose phosphate pathway and integrin signaling. Gene ontology based analysis classified majority of protein hits responsible for metabolic processes. Among these, only a single non-predictive protein spot was found to be a cancer cell specific hit, identified as Armadillo repeat-containing protein 8 (ARMC8). Pathway reconstruction studies showed that ARMC8 lies at the centre of cancer metabolic pathways. The findings in this report are suggestive of a regulatory role of ARMC8 in control of proliferation and differentiation in lung adenocarcinomas.
    Asian Pacific journal of cancer prevention: APJCP 02/2016; 16(9). DOI:10.7314/APJCP.2015.16.xx
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    ABSTRACT: Background: Vaspin and Retinol binding protein-4 (RBP4) are new adipokines mainly produced by adipose tissue. Considering that medullary thyroid carcinoma (MTC) is a malignant neuroendocrine tumor, and to date the relationship between serum levels of vaspin and RBP4 with MTC has not been studied, in this matched case-control study we evaluated their possible significance to this tumor type. Materials and Methods: A total of 45 patients with MTC (21 males and 24 females) and 45 healthy persons as a control group (24 males and 21 females) were selected. The two groups were matched for age, sex and body mass index. Serum Vaspin and RBP4 levels were measured by enzyme-linked immunosorbent assay (ELISA) methods in both groups. Also, weight and height were measured and body mass index was calculated too. Results: In total, patients with MTC had significantly higher serum vaspin levels compared to the controls (0.52ng/ml vs. 0.45ng/ml, P=0.0241). However, no significant difference was found in serum RBP4 concentrations between the patients with MTC and the controls (15.2±2.55 µg/ml versus 15.1±3.34 µg/ml, p>0.05). Conclusions: The results of this study demonstrated that serum RBP4 levels in MTC patients are not significantly different from those found in healthy individuals and did not correlate with MTC. On the other hand, higher levels of serum vaspin are associated with an increased risk of MTC. Thus Vaspin may be a novel and promising biomarker for diagnosis or confirmation of MTC in conjunction other specific tumor markers.
    Asian Pacific journal of cancer prevention: APJCP 01/2016; 16(15):6507-6512. DOI:10.7314/APJCP.2015.16.15.6507
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    ABSTRACT: The present study was conducted to investigate the effect of γ-radiation alone or combined with a cytotoxic drug, simvastatin, on viability and cell cycling of a myeloma cell line. P3NS1 myeloma cells were treated with the selected dose of simvastatin (0.1μM/l) 24 hours prior to γ-irradiation (0.25, 0.5 and 1Gy). The cell viability, induction of apoptosis, cell death, cell cycling, generation of ROS, and expression of P53, Bax, Bcl2, caspase3, PARP1 and Fas genes were estimated. The results indicated that simvastatin (0.1μM/l) treatment for 24 hours prior to γ- irradiation increased cell death to 37.5% as compared to 4.81% by radiation (0.5Gy) alone. It was found that simvastatin treatment before irradiation caused arrest of cells in G0/G1 and G2/M phases as assessed using flow cytometry. Interestingly, simvastatin treatment of P3NS1 cells increased the intracellular ROS production and decreased antioxidant enzyme activity with increased P53, Bax and Caspase3 gene expression while that of Bcl2 was decreased. Consequently, our results indicated that pre-treatment with simvastatin increased radio sensitivity of myeloma tumor cells in addition to apoptotic effects through an intrinsic mitochondrial pathway.
    Asian Pacific journal of cancer prevention: APJCP 11/2015; 16(16):7103-7110. DOI:10.7314/APJCP.2015.16.16.7103
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    ABSTRACT: The Mini Parasep SF fecal parasite concentrator is a newer modification of the closed concentration system, which can easily be adopted in any routine clinical pathology laboratory, therefore, here we describe our experience with the system in diagnosing Opisthorchis viverrini. A total of 199 fecal samples was submitted for routine examination in the clinical pathology laboratory of Suranaree University of Technology hospital, Nakhon Ratchasima province, Thailand during August to October 2015 were included in this prospective study. Out of all samples examined, 10 samples (5.03%) were positive with intestinal parasite including O. viverrini (2.01%), and followed by Strongyloided stercoralis (1.51%), Hookworm (0.5%), Taenia spp. (0.5%), and Entamoeba coli (0.5%). Distribution of intestinal parasites in relation to the methods used, and found that 4 samples (2.01%) were positive using the direct wet smear method while 10 (5.03%) were positive with the Mini Parasep SF method; the difference was statistically significant (X2-test = 0.076, p-value <0.05). Mean time for processing using the Parasep system was 6.03 min/sample, the conventional direct wet smear method at 0.3 min/sample. Cost per test, conventional direct wet smear method costing less than the Parasep method at USD 0.74/sample versus USD 1.47/sample. This is the first report of finding O. viverrini using MPSFC, indicates that Parasep concentration test is useful in the routine laboratory, increase in the yield of parasites as compared to direct microscopy, processing time and cost. However, comparison between Parasep concentration test and common concentration methods for O. viverrini detection are need required particularly concerning the epidemiological survey.
    Asian Pacific journal of cancer prevention: APJCP 11/2015; 16(18):in press.
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    ABSTRACT: Opisthorchis viverrini infection is associated with Cholangiocarcinoma particularly in the cases of chronic or re-infection. These are a serious health problem in northeastern and northern Thailand. A community base approach is required for surveillance. Therefore, a pilot project, re-examination of O. viverrini infection was conducted in the 3 districts of Nakhon Ratchasima province, Thailand, during June and October 2015. A total of 355 participants from 194,152 populations, was selected through multi-stage sampling method. O. viverrini infection was determined using modified Kato Katz thick smear technique. Participants were 229 males and 126 females, and age ≥ 30 years old. Prevalence of O. viverrini infection was 2.25% (8/355 participants). O. viverrini infection was slightly in female (3.17%), and age group between 41-50 years old (4.49%). Mueang Yang district had a highest of O. viverrini infection (2.82%), and followed by Bua Yai (2.48%), and Chum Phuang (1.84%), respectively. O. viverrini infection rate was increased from year 2012 to 2015 particularly in Bua Yai and Mueang Yang. These re-examine results indicate that opisthorchiasis is still problem in community of Nakhon Ratchasima province, therefore, the provincial-wide scale is need required, furthermore health education is need intervened in the infected group, and screening of cholangiocarcinoma is urgently concerned.
    Asian Pacific journal of cancer prevention: APJCP 11/2015; 16(18):in press.
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    ABSTRACT: BACKGROUND: Chromosomal aberrations identified in acute lymphoblastic leukemia (ALL) have an important role in disease diagnosis, prognosis and management. Information on karyotype and associated clinical parameters are essential to physicians for planning cancer control interventions in different geographical regions. MATERIALS AND METHODS: In this study, we present the overall frequency and distribution patterns of chromosomal aberrations in both children and adult de novo B lineage ALL Indian patients using conventional cytogenetics, interphase FISH and multiplex RT-PCR. RESULTS: Among the 215 subjects, cytogenetic results were achieved in 172 (80%) patients; normal karyotype represented 37.2% and abnormal 62.8% with a distribution as follows: 15.3% hypodiploidy; 10.3% hyperdiploidy; 15.8% t(9;22); 9.8% t(1;19); 3.7% t(12;21); 2.8% t(4;11); 2.8% complex karyotypes. Apart from these, we observed several novel, rare and common chromosomal rearrangements. Also, FISH studies using LSI extra-signal dual-color probes revealed additional structural or numerical changes. CONCLUSIONS: These results demonstrate cytogenetic heterogeneity of ALL and confirm that the incidence of chromosomal abnormalities varies considerably. To the best of our knowledge, this is one of the largest reported series of cytogenetic investigations in Indian B-lineage ALL cases. In addition, ongoing cytogenetic studies are warranted in larger groups of B-lineage ALL cases to identify newly acquired chromosomal abnormalities that may contribute to disease diagnosis and management.
    Asian Pacific journal of cancer prevention: APJCP 11/2015; 16(16):7219-7229. DOI:10.7314/APJCP.2015.16.16.7219
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    ABSTRACT: Several infectious agents are considered to be causes of cancer in humans mainly hepatitis B and C viruses, Helicobacter pylori, Clonorchis sinensis, and Opisthorchis viverrini. Here we described the evident research and the association between Helicobacter spp. and biliary tract cancer particularly Cholangiocarcinoma (CCA). Global epidemiological studies have been suggested that Helicobacter spp. are possible risk of biliary tract diseases. The molecular studies from other investigators support the linkage of Helicobacter spp. and CCA development. H. pylori, H. bilis, and H. hepaticus, are found in CCA, but the most of species are H. pylori and H. bilis. The type of CCA are associated with Helicobacter spp. included CCA, extrahepatic CCA, and common bile duct cancer. Up to the present, however, the results from different regions, material and method, sub-sites of cancer, and controls thus introducing heterogeneity, therefore, the comparison between co-Helicobacter spp.-CCA in the countries with low and high incident of CCA is required to settle the question. Furthermore, clarify the variation and role of Helicobacter species in this CCA, including pathogenesis of CCA through enhanced biliary cell inflammation and proliferation.
    Asian Pacific journal of cancer prevention: APJCP 11/2015; 16(17):in press.
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    ABSTRACT: Thailand is becoming the elderly society in nearly years. These figure is a serious problem situation especially their health. Chronic diseases are found frequently in elderly age that related to dietary intake, their behavior, and life style. Surin province has been reported that is a risk area of liver fluke and had a high incident of cholangiocarcinma especially in the elderly group. Therefore, this study aims to determine the nutritional status and associated factors among elderly in Surin province, northeast of Thailand. A community-based cross-sectional study was conducted among 405 elders aged 60 years old and above, between September 2012 and July 2014. The participants were randomized selected through systematic sampling method. Participants were completed the pre-designed questionnaire with the general information, food recorded, weight, height, waist circumference, and behavior regarding to food consume related to liver fluke infection. The data were analyzed using descriptive statistics and Spearman’s rank correlation coefficients. The majority of participants was female (63.46%), age between 60-70 years old (75.56%), elementary school (96.6%), lives with thire child (78.86%), and had an underlying diseases (38.27%). Carbohydrate (95.31%) was need to improve the consumption. The participants were under-nurtition (24.43%), over-nutrition (16.37%), and obesity 15.37%. Elderly had a waist circumference as the higher than normal level (34.04%). Gender, female, age 71-80 years old, elelmentary school, underlying diseases were statistical siginificant associated to poor nutritional status. The majority of them had a high knowledge (42.96%), moderately attitude (44.44%), and moderately practice (46.17%) regarding to food consume related to liver fluke infection. In conclusion, these findings data indicated that elderly age group had under-and over-nutritional status. Carbohydrate consumption was needed to improve. Some elderly are still behavior regarding to food consume that related to liver fluke infection is moderate level, therefore, health education pertaining good nutrition is need required.
    Asian Pacific journal of cancer prevention: APJCP 11/2015; 16(17):in press.
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    ABSTRACT: Background: Cervical cancer is the second most common malignancy among women worldwide, and women of reproductive age in Thailand. However, information on the behavior regarding cervical cancer in rural community Thailand is sparse. Objective: to assess the knowledge, attitude, and practice regarding cervical cancer (CC) among rural community women in Nakhon Ratchasima, Thailand using predesigned structured questionnaires. Materials and Methods: A cross-sectional survey was conducted in 8 villages of Non Sung district, Nakhon Ratchasima province, Thailand, during January to April 2015. Bloom’s taxonomy was used as a framework for the study. 265 women age between 30-60 years old were simple random sampling selected. All participants completed a predesigned questionnaire with 4 parts; demographic data, knowledge, attitude, and practice regarding cervical cancer. Descriptive statistics were used analysis in this study. Results: A majority of participants were age group 41-50 years old (42.6%), senior secondary school level (32.1%), marriage status (85.0%), agriculture (59.6%), and family income between 6,000-10,000 baht per monthly (54.3%). Of 63.4% and 68.7% participants had a high knowledge and a moderate level of attitude regarding CC. Of 41.1%, 48.7%, and 10.2% participants had a regularly, irregularly, and never screened CC, respectively. The reasonable of participants who had no screened CC, was shy (44.4%) and have no time (55.6%), respectively. Vaginal discharge and itching were the common causes of sign and symptom of participants who screened CC at health promotion hospital of sub-district. Conclusion: recent study indicates that CC is still a health problem in the rural community. Therefore, health education is need required, particularly in the participants who never CC screened.
    Asian Pacific journal of cancer prevention: APJCP 11/2015; 16(17):in press.