Journal of Maternal-Fetal and Neonatal Medicine (J MATERN-FETAL NEO M)

Publisher: European Association of Perinatal Medicine; Federation of Asia and Oceania Perinatal Societies; International Society of Perinatal Obstetricians, Informa Healthcare

Journal description

The official journal of The European Association of Perinatal Medicine, The Federation of Asia and Oceania Perinatal Societies, and The International Society of Perinatal Obstetricians.

Current impact factor: 1.21

Impact Factor Rankings

2015 Impact Factor Available summer 2015
2013 / 2014 Impact Factor 1.208
2012 Impact Factor 1.518
2011 Impact Factor 1.495
2010 Impact Factor 2.071
2009 Impact Factor 1.362
2008 Impact Factor 1.089
2007 Impact Factor 1

Impact factor over time

Impact factor

Additional details

5-year impact 1.69
Cited half-life 3.80
Immediacy index 0.20
Eigenfactor 0.01
Article influence 0.45
Other titles Journal of maternal-fetal & neonatal medicine (Online), Journal of maternal-fetal and neonatal medicine
ISSN 1476-7058
OCLC 49941200
Material type Document, Periodical, Internet resource
Document type Internet Resource, Computer File, Journal / Magazine / Newspaper

Publisher details

Informa Healthcare

  • Pre-print
    • Author can archive a pre-print version
  • Post-print
    • Author cannot archive a post-print version
  • Restrictions
    • 12 months embargo
  • Conditions
    • On author's personal website or institution website
    • Publisher copyright and source must be acknowledged
    • On a non-profit server
    • Must link to publisher version
    • Publisher's version/PDF cannot be used
    • NIH funded authors may post articles to PubMed Central for release 12 months after publication
    • Wellcome Trust authors may deposit in Europe PMC after 6 months
  • Classification
    ​ yellow

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: Objective: Randomized controlled trials have demonstrated that delayed umbilical cord clamping (DCC) in preterm infants results in improved neonatal outcomes, including increased hematocrit, and decreased rates of intraventricular hemorrhage (IVH) and packed red blood cell transfusions. We hypothesized that implementation of a DCC policy in preterm infants would result in similarly improved outcomes, despite initial clinician resistance. Study design: A DCC policy (30–60 s) for singleton infants <35 weeks gestation was implemented in September 2011. We conducted a pre-test/post-test analysis of neonatal outcomes among singletons delivered between 24 0/7 weeks and 34 6/7 weeks gestation from 2009 to 2013 (2 years pre-implementation and 2 years post-implementation). The primary outcomes were rates of policy compliance and four neonatal outcomes. Results: Despite multiple routes of policy dissemination, DCC was attempted in only 49% of the deliveries. In spite of this, infants delivered post-policy implementation (n = 196) had a significant decrease in IVH, significant increase in initial hematocrits, and improved temperatures compared with infants delivered pre-implementation (n = 204). Conclusion: After implementation of a DCC policy, preterm singleton infants had improved temperatures, increased hematocrits and a decreased prevalence of IVH without significant differences in adverse outcomes, suggesting that the benefits of DCC outweighed the risks.
    Journal of Maternal-Fetal and Neonatal Medicine 08/2015; DOI:10.3109/14767058.2015.1061496
  • [Show abstract] [Hide abstract]
    ABSTRACT: Introduction: Preeclampsia is one of the major causes of maternal and neonatal mortality. During pregnancy, the immune system must maintain the tolerance to the fetus, thus changes in the cytokine balance may result in a disturbed pregnancy. T helper cells play an important role in modulation of the immune system and are involved in this cytokine balance. Objective: Many studies have been performed to study the T cell composition in different compartments during pregnancy, although this is the first study in which T cells are evaluated in umbilical cord blood. Study design: Intracellular expression of INF-gamma, IL-17, IL-4 and forkhead foxP3 in CD4+ T cells was evaluated in umbilical blood from healthy pregnant and preeclamptic women using a flow cytometer. Results: Th2 and Treg cells levels were significantly diminished in preeclamptic compared to the healthy women, but no difference in Th1 and Th17 levels were found between both groups. Conclusions: Our data suggest that the cytokine balance is broken, encouraging the development of an exacerbated inflammatory response. Our results show that there is a shift, in the Th1/Th2, and the Th17/Treg balance, favoring skewness towards a proinflammatory status in the umbilical cord blood in preeclampsia.
    Journal of Maternal-Fetal and Neonatal Medicine 07/2015; DOI:10.3109/14767058.2015.1057811
  • [Show abstract] [Hide abstract]
    ABSTRACT: The increasing number of multiple pregnancies in recent years has raised a particular concern about the problems associated to these pregnancies. It still remains unclear whether twin deliveries, as currently conceived, provide the same future health chances to both fetuses. In this regard, it is worth mentioning that the effects of obstetric and neonatal care beyond the perinatal period have not often been evaluated. The main objective of this research was to analyze the impact of obstetric and perinatal variables on postnatal neuropsychological development, intelligence and school achievement of twin children. We conducted a cross-sectional and observational study on 62 pairs of 6-year-old twins, who were on their first year of primary education. All 124 children and their mother were individually assessed and perinatal clinical data were collected. A stratified multivariate analysis was performed using multiple linear regressions. The type of birth was the best predicting variable, so that the best results were achieved in children born in spontaneous vaginal deliveries. Comparatively, however, poorer scores were seen in males second twins born by the vaginal route in spatial structuring, non-verbal development and total development areas, especially in case of delivery before 37 weeks. Our study confirms the impact of some obstetric variables on school achievement and psychological development of twins.
    Journal of Maternal-Fetal and Neonatal Medicine 07/2015; DOI:10.3109/14767058.2015.1055724
  • Journal of Maternal-Fetal and Neonatal Medicine 07/2015; DOI:10.3109/14767058.2015.1059815
  • Journal of Maternal-Fetal and Neonatal Medicine 06/2015; DOI:10.3109/14767058.2015.1049148.
  • [Show abstract] [Hide abstract]
    ABSTRACT: Metabolic bone disease (MBD) is one of the important complications of prematurity. Early and adequate nutritional interventions may reduce the incidence and potential complications of MBD. The present study aimed to evaluate bone metabolism in twins via biochemical parameters and quantitative ultrasound (QUS) and to compare the results between twin pairs. Moreover, twin infants were evaluated in terms of potential risk factors likely to have impact on MBD. Forty-three pairs of twins were included in the study. Serum calcium, phosphorus, magnesium and alkaline phosphatase concentrations were assessed and bone mineral density was measured using QUS (speed of sound, SOS) at postnatal 30 days. Co-twin with the higher birth weight was assigned to Group 1 (n=36) and the other twin was assigned to Group 2 (n=36). Birth weight and head circumference were significantly higher in the infants of Group 1 compared to Group 2. No significant difference was found between the groups in terms of gender, history of resuscitation, length of stay in intensive care unit (ICU) or in the incubator, duration of total parenteral nutrition (TPN), type of nutrition, vitamin D use, biochemical parameters, and the SOS value. The factors likely to affect SOS, including type of pregnancy, maternal drug use, gender of infant, birth weight, head circumference at birth, gestational week, length of stay at the ICU, duration of TPN, type of nutrition, resuscitation, vitamin D use, and levels of calcium, phosphorus, magnesium, and alkaline phosphatase were entered into the model. The phosphorus level and maternal drug use were found to be the factors that significantly reduced SOS, whereas pregnancy after assisted reproductive techniques was found to be a significant enhancing factor.
    Journal of Maternal-Fetal and Neonatal Medicine 03/2015; DOI:10.3109/14767058.2015.1025743
  • [Show abstract] [Hide abstract]
    ABSTRACT: Background/Objective Approximately 10% of small for gestational age (SGA) infants fail to catch up. The relationship between postnatal growth and placental pathology in SGA infants remains unclear. Our aim was to assess the involvement of placental pathology in postnatal growth of SGA infants. Methods We retrospectively evaluated placental pathology and postnatal growth in single-pregnancy infants born after 37 gestational weeks in our institution, with both birth weight and length below -2 standard deviation scores (SDS) of the normal weight and length. 'Catch-up' was defined as height reaching -2 SDS before the second birthday. Pathology of the placenta was classified into: abnormality due to maternal factors or fatal factors, villitis of unknown etiology, other abnormalities, and no abnormality. Results Of 33,084 infants, 142 met our criteria and 49 of them had analyzable data. The overall catch-up rate was 84%. Catch-up growth took place in all infants with no placental abnormality and only 57% of infants with abnormality due to fatal factors. There was no significant relationship between catch-up rate and other factors. Conclusion Placental pathology is associated with postnatal growth in SGA children born at term. Placental abnormality due to fetal factors is related to poor catch-up rate.
    Journal of Maternal-Fetal and Neonatal Medicine 03/2015; DOI:10.3109/14767058.2015.1029911
  • [Show abstract] [Hide abstract]
    ABSTRACT: "What does it mean, Doctor?" and "Is it going to affect my baby in some way?". Those are the most typical questions of pregnant women to obstetricians. Answering is sometimes easier but placental calcification is not the case, since placental architecture and disease are two different faces of the same coin and the association between them is not completely clear. Placenta can function properly, even in the presence of architectural alterations, without any fetal consequences. So, remains the question, when does a placental structural anomaly become a sign of increased attention to maternal conditions, fetal development and wellbeing? The present review will analyze these concepts, with emphasis on placental calcification, its pathogenesis, and the state of the art regarding the influence of this finding on pregnancy outcomes among low-risk pregnant patients.
    Journal of Maternal-Fetal and Neonatal Medicine 03/2015; DOI:10.3109/14767058.2015.1023709
  • [Show abstract] [Hide abstract]
    ABSTRACT: Objective Radiography after fetal or perinatal death has become a routine part of post mortem diagnostics. However, only a selected subset of these babygrams or fetal post mortem skeletal surveys (FPSS) provides useful information. We investigated the indication for an FPSS. Methods Inclusion consisted of the routinely made FPSS (2002-2012) in our university hospital in cases of fetal or perinatal death up to 7 days after birth. We categorized the diagnostic value of the FPSS as no, minor, major or pathognomonic. Regression analysis was used to determine the selection criteria for a useful FPSS. Results 337 FPSS were included. 305 (91%) showed no or minor skeletal malformations. 14 (4,2%) FPSS had major skeletal malformations. In 18 (5,3%) cases the diagnosis was based on the pathognomonic skeletal malformations on the FPSS. 2 cases were false positive after major birth trauma. The presence of multiple skeletal malformations on prenatal ultrasound or at post mortem external inspection was highly indicative of a diagnostic FPSS (p<0.001). Conclusion The majority of the babygrams / FPSS has no contribution to the diagnostic process. Multiple skeletal malformations on prenatal ultrasound or post mortem external inspection are indicative for a diagnostic FPSS, and this should be the main selection criterion.
    Journal of Maternal-Fetal and Neonatal Medicine 03/2015; DOI:10.3109/14767058.2015.1029913
  • Journal of Maternal-Fetal and Neonatal Medicine 03/2015; DOI:10.3109/14767058.2015.1020128
  • [Show abstract] [Hide abstract]
    ABSTRACT: Indomethacin and ibuprofen, are commonly used in the treatment of hemodynamically significant patent ductus arteriosus (hsPDA). These drugs are associated with serious adverse events, including gastrointestinal perforation, renal failure and bleeding. The role of paracetamol has been proposed for the treatment of PDA. We report a series of 11 neonates (Birth weight: 415-1580 g; Gestational age: 23-30.3 weeks) who were treated with paracetamol for a hsPDA. Neonates with hs-PDA were treated with paracetamol in the presence of contraindications to ibuprofen or indomethacin. The condition of significant PDA was defined by the presence of at least one of the following criteria: internal ductal diameter???1.4 mm/kg body weight, left atrium to aortic root ratio?>?1.4, unrestrictive pulsatile transductal flow, reverse or absent diastolic flow in the descending aorta along with clinical findings. Intravenous paracetamol was given at doses 15 mg/kg every 6 hours for three days. Successful ductal closure was achieved in 10 out of 11 babies (90.9%). No adverse or side effects were observed during the treatment. On the basis of these results, paracetamol could be considered a promising and safe therapy for the treatment of PDA in preterm infants.
    Journal of Maternal-Fetal and Neonatal Medicine 03/2015; DOI:10.3109/14767058.2015.1029912
  • [Show abstract] [Hide abstract]
    ABSTRACT: verify if small for gestational age preterm newborns (SGA) represent a special risk group for carnitine deficiency. Secondary outcome: assess longitudinal differences of total carnitine (TC), free carnitine (FC) and acylcarnitines between SGA and appropriate (AGA) for gestational age. a retrospective study to evaluate carnitine and acylcarnitines profile on 144 very-low-birth weight newborns (VLBW), classified in AGA (n=73) and SGA (n=71), was performed by tandem mass spectrometry, during their first 5 weeks of life. Carnitine deficiency was defined as FC< 40µmol/L and FC/TC<0.7. carnitine deficiency was observed in the two study groups throughout the monitoring period (maximum FC: 36.05µmol/L in AGA and 32.24µmol/L in SGA). FC/TC remains under 0.7 in both with progressive improvement. Unlike expected, a comparatively higher value of TC, FC and total acylcarnitines (tAC) was found in SGA during the first two weeks, with significant relevance on day third-fifth, specially for tAC (p<0.001). The only acylcarnitine with persistently lower value in SGA is C5 (p<0.05 in first two weeks). a carnitine deficiency was demonstrated in all VLBW. Despite birth weight restriction has been suggested as a risk factor for impaired carnitine status, in our serie, SGA was not related with higher carnitine deficiency.
    Journal of Maternal-Fetal and Neonatal Medicine 03/2015; DOI:10.3109/14767058.2015.1024647