European Journal of Scientific Research

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    0.74
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  • ISSN
    1450-202X

Publications in this journal

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    ABSTRACT: The search for alternatives to synthetic drugs, led to the investigation of the chemical composition, antiradical, anti-inflammatory and antifungal potentials of the essential oils from fruits of three Annonaceae spices namely Monodora myristica, Xylopia aethiopica and Xylopia parviflora. The essential oils were extracted by hydrodistillation and analyzed using Gas Chromatography (GC) and Gas Chromatography coupled with Mass spectrometry (GC/MS). They were further subjected to DPPH.scavenging assay, 5-lipoxygenase inhibition assay on one hand and the Agar dilution test on the other hand to determine their effect on mycelia growth of Aspergillus fumigatus, Aspergillus flavus and Aspergillus niger isolates. The extraction yields were 0.74, 2.18 and 2.33% respectively for X. parviflora, X. aethiopicaand M. myristica. These essential oils were mainly constituted of monoterpenesasα-phellandrene (57.8%) and p-cymene (12.7%) for M. myristica, ß-pinene (46.9%) and a-pinene (16.8%) for X. parvifloraand lastly ß-pinene (25.8%) and a-pinene (11.5%) for X. aethiopica. The latter portrayed the highest antiradical power (PA= 2.28x10-5) and the most effective inhibitor of 5- lipoxygenase with an IC50 of 515ppm whereas M. myristica and X. parviflora displayed poor inhibition with IC50 values of 1829 ppm and 1164 ppm respectively. These essential oils were fungicidal on the three aspergilla with X. parviflora appearing to be the most active with MIC ranging from 4x103mg/L to 5.75x03mg/L. The results of this study indicate that these essential oils could be used as potent fungi growth inhibitors. Keywords: Antiradical, anti-inflammatory, antifungal, Monodora myristica,Xylopia aethiopica, Xylopia parviflora.
    European Journal of Scientific Research 03/2014; 120(3):303-314.
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    ABSTRACT: The article highlight the conceptual statements the model basis formation of the early prevention systems crisis forecasting. The base model is presented as complex interrelated module based on macroeconomic indicators forecasting module adjusted for cycle-formation factors; regional development indicators forecasting module adjusted for cycle-formations; forecasting module of the economic crises and catastrophes in the socio-economic territories development. The developed model basis relies on the econometric modeling, Fourier analysis, adaptive filtration, multidimensional analysis and catastrophes theory methods. Model also give an opportunity to study the resonance phenomena in the economic indicators dynamics, forecast the local and global crises, and elaborate the strategic preventive arrangements seeking to localize crisis processes in the territories economic system development dynamics.
    European Journal of Scientific Research 02/2014; 118(1):7-22.
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    ABSTRACT: Condensation of 1-naphthylamine with acetone in the presence of Et3N·HCl as a catalyst gave the corresponding 1-naphthyl (1- methylethylidene) iminium chloride (1). The salt was identified and characterized by multinuclear NMR (1H and 13C NMR) and IR spectroscopy. In solution, the two methylenic hydrogens of the N-isopropyl moiety are anisochronous. This result was confirmed by the X-ray investigation of 1 in the solid state. 1 crystallized in the orthorhombic space group Pbca, a = 10.8668(8)Å, b = 11.1758(9) Å, c = 18.8726(18)Å, α = γ = β = 90 °, Z = 8. The structure was solved by direct methods, and retined by full-matrix least squares techniques to an R factor of 0.0308 for 1874 observed reflections. In the crystal the 1-naphthyl (1-methylethylidene) iminium cation and chloride anion are linked by N–H···Cl hydrogen bond.
    European Journal of Scientific Research 02/2014; 10(1):247-251.
  • European Journal of Scientific Research 01/2014; 118(3):326-335.