Australian and New Zealand Journal of Ophthalmology Impact Factor & Information

Publisher: Royal Australian College of Ophthalmology; Ophthalmological Society of New Zealand, Blackwell Publishing

Journal description

Discontinuted. Now Clinical and Experimental Ophthalmology.

Current impact factor: 0.00

Impact Factor Rankings

Additional details

5-year impact 0.00
Cited half-life 0.00
Immediacy index 0.00
Eigenfactor 0.00
Article influence 0.00
Website Australian and New Zealand Journal of Ophthalmology website
Other titles Australian and New Zealand journal of ophthalmology (Online)
ISSN 1440-1606
OCLC 45461900
Material type Document, Periodical, Internet resource
Document type Internet Resource, Computer File, Journal / Magazine / Newspaper

Publisher details

Blackwell Publishing

  • Pre-print
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    • Some journals impose embargoes typically of 6 or 12 months, occasionally of 24 months
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    • Articles in some journals can be made Open Access on payment of additional charge
    • 'Blackwell Publishing' is an imprint of 'Wiley'
  • Classification
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Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: Purpose: To describe the features of posterior uveitis in patients who either developed or were known to have, biopsy-proven Hodgkin’s disease (HD).Methods: Four patients were identified who were attending the uveitis clinic. Their charts were reviewed retrospectively and information on their HD was obtained from other hospitals where necessary. Their case histories are presented.Results: Two patients presented with uveitis prior to the diagnosis of HD and in the other two, the HD was thought to be in remission. The commonest ocular signs were of vitritis and discrete, white, chorioretinal lesions. No difference in the ocular findings were apparent between those who had a known diagnosis of HD and the those that did not.Conclusions: HD can occur in the eye and can mimic posterior uveitis. In two of the patients, the uveitis preceded the diagnosis of HD and at the time of presentation all investigations were normal. No specific diagnostic features were apparent, though three of the patients had vitritis and chorioretinal lesions.
    Australian and New Zealand Journal of Ophthalmology 07/2008; 27(5):326 - 330. DOI:10.1046/j.1440-1606.1999.00224.x
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    ABSTRACT: Purpose: The purpose of this study was to examine the association between type of vision impairment and disability and the handicap or impact of vision loss on functioning.Methods: Participants were interviewed for the Royal Victorian Institute for the Blind Employment Survey, and asked to self-report whether totally blind or not (vision impaired). Causes of visual impairment were also reported. Eyesight was rated on a scale from 0 (completely blind) to 10 (best possible eyesight). Difficulty with mobility, personal care, household activities, work and hobbies and social interactions were also rated. Participants with vision impairment also rated their level of disability in reading and seeing other people’s reactions using the same scale.Results: Of the 250 participants, 39 self-reported total blindness. Participants with vision impairment experienced greater levels of difficulty in almost all areas than people who self-reported total blindness. People with vision impairment due to glaucoma and macular degeneration reported significantly more difficulty with reading newspapers, while there was a borderline significant relationship between difficulty with seeing people’s reactions and macular degeneration.Conclusions: In summary, we found that difficulty associated with everyday tasks was greater than might be expected from self-report of vision. This study confirms the need for visual function tools to supplement the use of objective visual acuity measurements in people with vision impairment.
    Australian and New Zealand Journal of Ophthalmology 07/2008; 27(3‐4):204 - 207. DOI:10.1046/j.1440-1606.1999.00200.x
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    ABSTRACT: Purpose: To test the hypothesis that access to extravasated plasma protein IgG may influence photoreceptor survival following laser photocoagulation and to determine whether this correlates with the retinal glial reaction. Methods: A total of 45 rats (18 Royal College of Surgeons (RCS) dystrophic and 18 RCS-rdy+ congenic control) were used for this experiment. Nine non-lasered littermates of same age were used as controls. The superior retinas of postnatal day 23 rats were irradiated with a grid pattern of 40 argon green laser lesions of 50 μm in diameter and two powers (150 and 300 mW) for 0.2 s. At various times after laser lesions (up to 14 days), animals were perfused, the retinas snap frozen and sectioned on a cryostat. A one-step immunohistochemical technique was used by incubating with rabbit anti-rat IgG conjugated directly to horseradish peroxidase. Adjacent sections were processed using an antibody to glial fibrillary acidic protein (GFAP) by the standard avidin–biotin complex method. Results: The labelling pattern for extravasated IgG after laser lesion was very similar in both RCS and RCS-rdy+ rat retinas. At 6, 12 and 24 h after lesions, IgG immunoreactivity (IR) was very intense in the lesion core and flanks. The outer plexiform layer (OPL) and photoreceptor inner segments provided a ready pathway for lateral spread of IgG. However, in the outer nuclear layer (ONL), IgG localization was much more restricted. Despite very intense IgG IR in the ONL of the coagulated lesion core, there was always a very sharply delineated boundary where the label abruptly halted. The GFAP labelling in both RCS dystrophic and RCS-rdy+ congenic control rat retinas showed that this boundary was between normal and necrotic cells because there was a core where GFAP was not produced by Müller cells. By 2 days after lesions, the coagulated cells in the lesion core were being removed by phagocytic cells that were IgG IR. Labelled phagocytic cells were also found among the inner and outer segment region on the lesion flanks. There was still IgG IR in the lesion, but the label was faint. No IgG IR was found in the retina at 3, 4, 7 and 14 days after lesions. Absorption control with pure rat IgG showed the label to be specific. Conclusions: The extravasated IgG was derived from the choroidal circulation because at no stage was IgG localized around the retinal vasculature. The IgG labelling was surprisingly widespread and, therefore, did not correlate with photoreceptor sparing, although it preceded the widespread Müller cell expression of GFAP and may, therefore, trigger glial reaction.
    Australian and New Zealand Journal of Ophthalmology 07/2008; 27(2):117 - 125. DOI:10.1046/j.1440-1606.1999.00164.x
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    ABSTRACT: Purpose: To develop a system of categorizing white cataracts so that the salient features, as would be pertinent to phacoemulsification surgery, could be recognized pre-operatively.Methods: Patients with total cataracts were carefully evaluated using slit-lamp biomicroscopy and slit-lamp photography. An attempt was made to determine whether pre-operative evaluation could ascertain the presence or absence of features of these cataracts that often cause surgical difficulties, namely, increased intralenticular pressure (ILP), milky cortex and brown nuclear colour.Results: Using a standardized method of biomicroscopic evaluation, it was found that the status of the ILP, cortex and nuclear colour could be determined consistently. Surgical strategies based on such a system of categorization has permitted white cataracts to be consistently managed using phacoemulsification.Conclusions: Systematic pre-operative evaluation and categorization of white cataracts based on the ILP, status of the cortex and nuclear colour can permit proper surgical planning and successful management of such cases with phacoemulsification.
    Australian and New Zealand Journal of Ophthalmology 07/2008; 27(1):53 - 56. DOI:10.1046/j.1440-1606.1999.00150.x
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    ABSTRACT: Purpose: This study evaluates the in vitro potency, stability and contamination of the fortified ophthalmic antibiotic preparations of cefazolin, vancomycin, gentamicin and tobramycin stored for 4 weeks. The effects of the different solvents and storage temperatures on the antimicrobial potency and stability were also examined. Methods: The fortified stock solution of cefazolin and vancomycin were prepared by reconstituting with 0.9% sodium chloride and with artificial tears. Gentamicin and tobramycin were prepared by adding parenteral forms into their commercial ophthalmic solutions. The antimicrobial potency was measured by the minimum bactericidal concentration for cefazolin (33.3 mg/mL) and vancomycin (31 mg/mL) against Staphylococcus aureus, and for tobramycin (13.5 mg/mL) and gentamicin (13.5 mg/mL) against Pseudomonas aeruginosa. The stability of solution was evaluated by measuring absorbance spectra and pH. During the study period the levels of contamination of the stock solutions were examined by culturing on blood and on Sabouraud-dextrose media. Results: There were no differences in the antimicrobial potency of the cefazolin, vancomycin and tobramycin within the 4-week period; however, the potency of gentamicin was decreased at both temperatures after 21 days. It was found that different solvents or storage temperatures had no effect on the potency. Throughout the 4-week period, no change was found in the absorbance spectra of gentamicin and tobramycin, whereas the absorbance spectra of cefazolin and vancomycin stored at 24°C increased in both of the solvents used (P < 0.05). In all of the antibiotics, pH changed at 24°C after 7–10 days; however, at 4°C, only the pH of tobramycin exhibited changes after 14 days (P < 0.05). No contamination was detected in the stock solutions during the study period. Conclusion: Topical fortified antibiotic solutions used for longer than 7 days should be stored at ≤ 4°C, those stored at 24°C should be discarded after 7 days.
    Australian and New Zealand Journal of Ophthalmology 07/2008; 27(6):426 - 430. DOI:10.1046/j.1440-1606.1999.00239.x
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    ABSTRACT: Should older people eat more carrots, or at least increase their carotene intake to prevent loss of night vision? Participants in the Blue Mountains Eye Study were asked about their ability to see in the dark. Nutrient and food intake were estimated from a food frequency questionnaire. Associations between self-reported poor night vision and estimated nutrient intake were investigated using logistic regression. Poor night vision among women was associated with higher beta-carotene (P for trend = 0.03) and total vitamin A intake (P for trend = 0.048). Increased consumption of carrots, but no other food high in beta-carotene, was associated with significant increased reporting of poor night vision among women (P for trend = 0.04). While carrot intake may protect against difficulty in seeing at night, it is probable that people attributing poor driving ability to their vision may be eating more carrots in the hope of reversing this decline.
    Australian and New Zealand Journal of Ophthalmology 07/2008; 27(3‐4):200 - 203. DOI:10.1046/j.1440-1606.1999.00187.x
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    ABSTRACT: There is accumulating evidence that an increased expression of vascular endothelial growth factor from retinal pigment epithelial cells may be important in choroidal neovascularization. In vivo studies have demonstrated that subretinal injection of recombinant adenovirus vectors produces long-term transgene expression specifically within retinal pigment epithelial cells. A recombinant adenovirus encoding of vascular endothelial growth factor (Ad.RSV.VEGF) was therefore produced and characterized in order to determine whether an upregulation of vascular endothelial growth factor expression is sufficient to induce choroidal neovascularization. Ad.RSV.VEGF was produced by homologous recombination and its identity confirmed by restriction enzyme analysis. Ad.RSV.VEGF was characterized in vitro by the transduction of cultured retinal pigment epithelial cells. The in vitro characterization confirmed vascular endothelial growth factor mRNA and protein expression from Ad.RSV.VEGF and demonstrated the biological activity of the vascular endothelial growth factor protein. A preliminary in vivo study suggested that the subretinal injection of Ad.RSV.VEGF induced vascular leakage.
    Australian and New Zealand Journal of Ophthalmology 07/2008; 27(3‐4):250 - 253. DOI:10.1046/j.1440-1606.1999.00182.x
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    ABSTRACT: A procedure is described for generating stimuli to study the detection of noise components in motion signals. By using random dots with intensities distributed according to a Gaussian probability function, a temporally and spatially continuous mixture of signal and noise components can be realized in random dot kinematograms. These stimuli were used in a noise detection task, a signal detection task and a direction discrimination task. Signal-to-noise ratio (‘coherence’) thresholds for the signal detection and direction discrimination tasks were consistent with previous research. Noise can be detected at levels of approximately 0.5–2.5%, depending on the size of the motion stimulus. We argue that the noise in the motion stimulus becomes detectable when it exceeds the noise intrinsic to the various stages of motion processing. Therefore, the method provides a simple procedure for obtaining measures of equivalent input noise and can be used for estimating internal noise levels of motion processing mechanisms.
    Australian and New Zealand Journal of Ophthalmology 07/2008; 27(3‐4):254 - 257. DOI:10.1046/j.1440-1606.1999.00181.x
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    ABSTRACT: Purpose: This experiment reports the independence of first- and second-order processing mechanisms in form perception. Methods: Symmetrical dot patterns were created using either luminance-increment dots (luminance above background), or texture-defined dots (average luminance equal to background). The proportion of luminance increment or texture dots defining each pattern was varied among fields of noise dots of the same type to determine symmetry detection thresholds. Results: Differences in detection thresholds were found between luminance- and texture-defined patterns. Further, symmetry detection thresholds for luminance-increment dot patterns were resistant to noise defined by dots of opposite contrast polarity (luminance-decrement dots) or texture, while texture-defined patterns were resistant to neither texture nor luminance-decrement noise. Conclusions: These data suggest that symmetry perception, along with other types of form perception, use both first- and second-order processing mechanisms. The data are compatible with a second-order system that includes a negative half-wave rectifying non-linearity.
    Australian and New Zealand Journal of Ophthalmology 07/2008; 27(3‐4):268 - 270. DOI:10.1046/j.1440-1606.1999.00198.x
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    ABSTRACT: Background: As part of a project to improve diabetes care in Fiji, we assessed the magnitude of problems posed by diabetic retinopathy in that country and compared the findings with those from an Australian diabetes centre. The relationship between diabetic retinopathy and nephropathy was also examined in a subset of patients. Methods: A medical team from Australia screened a total of 446 type 2 diabetic patients (ethnicity: Fijian/Indian 16/84%) for diabetic retinopathy in five towns from the Western Division of Viti Levu, Fiji. The findings were compared with data obtained from 1659 type 2 diabetic patients who had attended an Australian diabetes centre (ethnicity: Indian/ Anglo-Celtic 12/88%). In both cohorts, retinopathy was assessed by direct fundoscopy and a spot urine sample was collected for determination of albuminuria (defined as a concentration > 50 mg/L). Results: The prevalence of diabetic retinopathy increased linearly with duration of diabetes. It was higher in Fiji, even when cases from the same ethnicity (i.e. Indians) and duration were compared (P < 0.05). Extrapolation of the data points suggests a delay in the diagnosis of diabetes in Fiji. Of those patients with retinopathy in Fiji, more than half had moderate to severe non-proliferative diabetic retinopathy or proliferative diabetic retinopathy, significantly higher than patients in the Australian cohort (χ2 = 29.2; P < 0.0001). Retinopathy was not a predictor of albuminuria in Fijian Indians (χ2 = 0.4; P = 0.5). In contrast, Australian Indians with retinopathy had significantly more albuminuria (χ2 = 10.2; P = 0.001). Conclusions: Severe diabetic retinopathy is common in both ethnic groups in Fiji. A delay in the diagnosis of diabetes as well as poor glycaemic control are possible factors. The availability of laser therapy is important to prevent loss of vision, but it is also essential that appropriate training of health professionals is integrated with a programme of diabetic complication screening to support this form of therapy.
    Australian and New Zealand Journal of Ophthalmology 07/2008; 27(1):9 - 13. DOI:10.1046/j.1440-1606.1999.00146.x

  • Australian and New Zealand Journal of Ophthalmology 06/2008; 19(1):89 - 90. DOI:10.1111/j.1442-9071.1991.tb01811.x

  • Australian and New Zealand Journal of Ophthalmology 06/2008; 19(1):3 - 7. DOI:10.1111/j.1442-9071.1991.tb01793.x
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    ABSTRACT: We report a case where the detection of antineutrophil cytoplasmic antibody (ANCA) at the time of diagnosis of a case of sclero-uveitis predicted the later development of systemic features and prompted an early and definitive diagnosis of systemic vasculitis.
    Australian and New Zealand Journal of Ophthalmology 06/2008; 19(1):71 - 73. DOI:10.1111/j.1442-9071.1991.tb01804.x
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    ABSTRACT: Cytomegalovirus (CMV) infection of the retina is the commonest potentially blinding ocular manifestation of AIDS. Recently the acyclic nucleoside dihydroxypropoxymethyl guanine (DHPG, ganciclovir) has become available to treat sight-threatening CMV retinopathy. This paper reports the clinical features and results of ganciclovir therapy in 48 patients seen over a four-year period. Seven patients were excluded from the study due to inadequate followup, leaving 41 patients as the study group. All patients responded clinically to this therapy. Patients were treated initially with high-dose ganciclovir (1 0 mglkglday) and then continued on lower dose treatment (5 mg/kg/day) indefinitely. Significant bone marrow toxicity developed in 12 patients (29.3%) requiring temporary cessation of therapy. Patients treated with ganciclovir retained vision and had increased survival times when compared to untreated patients. A poor visual outcome occurred when there was involvement of the macula or optic acquired nerve head at presentation or when there was an interruption of ganciclovir therapy.
    Australian and New Zealand Journal of Ophthalmology 06/2008; 18(4):385 - 391. DOI:10.1111/j.1442-9071.1990.tb01822.x
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    ABSTRACT: Several neurological syndromes, including syncope, convulsions, amnesia, transient ischaemic attacks and cerebral infarction, have been associate with mitral valve prolapse. It has been presumed that emboli may account for some of these. We report a case of retinal infarction in association with mitral valve prolapse.
    Australian and New Zealand Journal of Ophthalmology 06/2008; 15(1):79 - 82. DOI:10.1111/j.1442-9071.1987.tb01785.x

  • Australian and New Zealand Journal of Ophthalmology 06/2008; 18(4):437 - 437. DOI:10.1111/j.1442-9071.1990.tb01831.x
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    ABSTRACT: Visual acuity was measured in both preterm and full-term infants by means of forced-choice preferential looking. The ages of infants tested ranged from one month to 12 months. The results of both groups were considered and compared in terms of natal and conceptional age. The data suggested that preterm infants show visual responses equivalent to their full-term counterparts by nine months of age. Trends indicate that visual acuity development in healthy preterm infants appears to be accelerated when compared with full-term infants of the same post-conceptional age.
    Australian and New Zealand Journal of Ophthalmology 11/2007; 17(1):23 - 26. DOI:10.1111/j.1442-9071.1989.tb00485.x
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    ABSTRACT: Parry Romberg syndrome is a rare disorder characterised by progressive hemifacial atrophy that is usually unilateral, involving the skin, subcutaneous tissue, and subsequently the muscle, cartilage and bone. Previous cases with various ocular manifestations have been reported. A case of Parry Romberg syndrome with retinal vasculitis is reported.
    Australian and New Zealand Journal of Ophthalmology 11/2007; 19(4):295 - 298. DOI:10.1111/j.1442-9071.1991.tb00675.x
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    ABSTRACT: Purpose: Activated protein C (APC) resistance has recently been reported as conferring a sevenfold increase in the risk of venous thrombosis. It is linked to a genetic mutation in the factor V gene which occurs commonly (about 2% to 4% of the community have the mutation). Glaucoma patients with nerve fibre layer (NFL) haemorrhages on the optic disc and patients with central retinal vein occlusion (CRVO) were tested for APC resistance to determine if there was an association. Methods: Twenty-three patients with glaucomatous NFL haemorrhages and 23 patients with CRVO were tested. The CRVO cases included 11 with relatively young age of onset (mean 45.1 ± 6.9 years) without conventional vascular risk factors. Eighty randomly selected Red Cross blood donor samples and 33 staff members were tested as controls. Clotting times with and without exogenous APC were recorded and an APC ratio determined. Cases with APC resistance were tested to confirm that they had the factor V Leiden gene. Results: No cases of APC resistance were identified in the glaucoma patients and only one of the younger CRVO patients tested positive, but four of 113 controls tested positive. The difference in prevalence between groups is not significant. The mean APC ratios for the three groups were very similar: NFL haemorrhages 5.46(±1.62), CRVO 5.70(±1.56), controls 5.34(±1.19) p>0.5. Conclusion: There was no clear association detected between glaucomatous NFL haemorrhages or CRVO and APC resistance in this sample of patients. This negative finding is important due its known association with venous thrornbosis elsewhere in the body.
    Australian and New Zealand Journal of Ophthalmology 11/2007; 24(3):199 - 205. DOI:10.1111/j.1442-9071.1996.tb01581.x
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    ABSTRACT: This case report describing Acanthamoeba keratitis in a 41-year-old male disposable contact lens wearer, adds some sobering and some encouraging information for the future management of this infection. Initial treatment with topical propamidine isethionate (Brolene) and polymyxin B/neomycin/ gramicidin (Neosporin) led to an unsatisfactory clinical response. Topical miconazole 1%, prednisolone acetate 0.12% and oral itraconazole were then added to his treatment. This was later discontinued on noticing ipsilateral toxic cataract formation and an unresponsive pupil. The above medications were replaced with topical polyhexamethylene biguanide (PHMB) 0.02%, which we had shown to have superior in-vitro amoebicidal activity when compared to the other antiamoebic agents used in this case. Withdrawal of the multitreatment schedule and commencement of PHMB was associated with resolution of his keratitis, healing of a large epithelial defect and settling of severe conjunctivitis. The identical Acanthamoeba strain was isolated from the patient's contact lens storage case and cornea, possibly implicating the contaminated contact lens case in the aetiology of his keratitis. This is the first Australasian experience using PHMB to treat Acanthamoeba keratitis. It appears to be a promising new treatment for this infection.
    Australian and New Zealand Journal of Ophthalmology 11/2007; 22(1):73 - 76. DOI:10.1111/j.1442-9071.1994.tb01700.x