Scandinavian Cardiovascular Journal (SCAND CARDIOVASC J )

Publisher: Taylor & Francis


Formerly Scandinavian Journal of Thoracic and Cardiovascular Surgery, Scandinavian Cardiovascular Journal is published by the Society for the Publication of the Key Foundation, Sweden. As of 1997, it is promoted in collaboration between the Scandinavian Societies of Cardiology in Denmark, Finland, Iceland, Norway and Sweden and the Scandinavian Association for Thoracic Surgery, which all have adopted the journal as their official organ. The principal aim of the journal is to promote cardiovascular research that crosses the borders between disciplines. The journal is a forum for the entire field of cardiovascular research, basic and clinical, thoracic surgery, transplantation, interventional cardiology and extracorporeal technology. Manuscripts will be reviewed for possible publication on the understanding that they have not been published, simultaneously submitted or accepted for publication elsewhere. Instructions for authors should be strictly followed. The journal is published in English, with six issues a year.

  • Impact factor
    Show impact factor history
    Impact factor
  • 5-year impact
  • Cited half-life
  • Immediacy index
  • Eigenfactor
  • Article influence
  • Website
    Scandinavian Cardiovascular Journal website
  • Other titles
    Scandinavian cardiovascular journal (Online)
  • ISSN
  • OCLC
  • Material type
    Document, Periodical, Internet resource
  • Document type
    Internet Resource, Computer File, Journal / Magazine / Newspaper

Publisher details

Taylor & Francis

  • Pre-print
    • Author can archive a pre-print version
  • Post-print
    • Author can archive a post-print version
  • Conditions
    • Some individual journals may have policies prohibiting pre-print archiving
    • On author's personal website or departmental website immediately
    • On institutional repository or subject-based repository after either 12 months embargo for STM, Behavioural Science and Public Health Journals or 18 months embargo for SSH journals
    • Publisher's version/PDF cannot be used
    • On a non-profit server
    • Published source must be acknowledged
    • Must link to publisher version
    • Set statements to accompany deposits (see policy)
    • The publisher will deposit in on behalf of authors to a designated institutional repository including PubMed Central, where a deposit agreement exists with the repository
    • STM: Science, Technology and Medicine
    • SSH: Social Science and Humanities
    • Publisher last contacted on 25/03/2014
    • 'Taylor & Francis (Psychology Press)' is an imprint of 'Taylor & Francis'
  • Classification
    ​ green

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: Objective: To assess the relationship between hematological inflammatory signs, cardiovascular risk (CV) factors and prognosis in patients presenting with acute myocardial infarction (AMI) and coronary artery ectasia (CAE). Design: We investigated 3321 AMI patients who required urgent primary percutaneous intervention, in two centres in the United Kingdom between January 2009 and August 2012. Thirty patients with CAE were compared with 60 age- and gender-matched controls. Blood was collected within 2 hours of the onset of chest pain. CV risk factors were assessed from the records. Major acute cardiac events and/or mortality (MACE) over two years were documented. Results: CAE occurred in 2.7 % and more often affected the right (RCA) (p= 0.001) and left circumflex artery (LCx) (0.0001). Culprit lesions were more frequently related to atherosclerosis in non-CAE patients (p=0.001). Yet, CV risk factors failed to differentiate between the groups, except diabetes, which was less frequent in CAE (p= 0.02). CRP was higher in CAE (p=0.006), whereas total leucocyte, neutrophil counts and neutrophil/lymphocyte ratio (N/L ratio) were lower (p=0.002, 0.002 and 0.032, respectively) than among non-CAE. This also was the case in diffuse vs. localized CAE (p=0.02, 0.008 and 0.03, respectively). The MACE incidence did not differ between CAE and non-CAE (p=0.083) patients, and clinical management and MACE were unrelated to the inflammatory markers. Conclusion: In AMI, patients with CAE commonly have aneurysmal changes in RCA and LCx, and their inflammatory responses differ from those with non-CAE. These differences did not have prognostic relevance, and do not suggest different management.
    Scandinavian Cardiovascular Journal 03/2014;
  • Scandinavian Cardiovascular Journal 01/2011; 45:14.
  • [Show abstract] [Hide abstract]
    ABSTRACT: In 20 dogs, the spleen was split in two parts, and the cranial portion was pulled through the diaphragm and sutured to the heart. In 8 of 12 dogs, the epicardium was peeled off. In 9 of the dogs local myocardial is-chaemia was attempted by ligating coronary artery branches and in one dog an aluminium needle was inserted into a coronary artery so as to produce gradual thrombosis. The dogs were killed or died 2–111 days after the operation. The heart and spleen were removed en bloc. Mixobar was injected through the splenic artery at a pressure of about 80 mm Hg. A good filling of the splenic vasculature was produced in 12 specimens. These were used for further examinations. Fibrosis was found in the “contact area” between the spleen and myocardium of dogs surviving more than 7 days. The degree of fibrosis was roughly correlated to survival time. Contrast medium was found in the “contact area” in all but 2 of the 12 specimens. This was seen as early as 2 days after the operation and also in dogs with intact epicardium. Contrast medium in the coronary vessels was found in one specimen. Spleeno-myocardial pexia does not appear to be a worthwhile method for producing myocardial revas-cularization in dogs.
    Scandinavian Cardiovascular Journal 07/2009; 4(2).
  • [Show abstract] [Hide abstract]
    ABSTRACT: The morphological and physiological characteristics in five cases of Barrett's syndrome are described. All the patients had a stricture at the junction between the two types of epithelium as well as hiatal hernia with reflux. In addition, three patients had ulcers in the area lined with columnar epithelium. The epithelium distal to the stricture was studied by light microscopy in all 5 cases and by electron microscopy in one. No parietal or main cells were demonstrated, but the surface epithelium showed the same characteristics as the surface epithelium in the stomach. Electron microscopy disclosed two types of granulated cells, which have so far been detected only in the stomach. It is concluded, therefore, that the oesophageal mucosa was of the same type as in the cardia. A finding of particular interest was granulated cells of type G, showing the same electron microscopic characteristics as the gastrin-producing cells in the stomach. In one case manometry was used as a diagnostic aid. This procedure must be considered a valuable supplement to cinematographic X-ray examination and oeso-phagoscopy. This applies especially in differentiating between cases of Barrett's syndrome with low stenosis and cases of hiatal hernia with oesophagitis and stricture, but without abnormal epithelial lining.
    Scandinavian Cardiovascular Journal 07/2009; 6(2).
  • [Show abstract] [Hide abstract]
    ABSTRACT: A spontaneous development of left-sided chylothorax was observed in an otherwise healthy patient. Repeated thoracocenteses were performed and followed by left-sided explorative thoracotomy, including ligation of the thoracic duct. Exudation of lymph into the pleural cavity was thus arrested. The various causes of a development of chylothorax are summarized, and the basis on which the diagnosis may be established is briefly discussed together with the therapeutical results.
    Scandinavian Cardiovascular Journal 07/2009; 8(2).
  • [Show abstract] [Hide abstract]
    ABSTRACT: Thymolipoma is a rare, benign, mediastinal tumour. Thirty-four cases have previously been reported in the literature available to us. One further case is described here. A symptomless 35-year-old man had been misdiagnosed for cardiac enlargement 20 years before he was sent to the hospital. A tumour of 2 000 g was surgically removed. It was asymptomatic, consisted of a large solid mass and extended as long branches in the loose tissue between the mediastinal organs. Histological examination revealed mature fat tissue with islets and strands of thymic tissue.
    Scandinavian Cardiovascular Journal 07/2009; 7(1).
  • [Show abstract] [Hide abstract]
    ABSTRACT: A report is presented of 93 patients referred for specialist management of thoracic injuries in the 5-year period 1973–1978. Penetrating trauma to the thorax had been sustained by 18 patients and blunt trauma by 75. Falls and traffic accidents were the most common causes (32 and 35 cases). Rib fractures were the most frequent lesions, and 10 of these 67 patients had flail chest. Hemothorax and/or pneumothorax were found in four-fifths of the patients. The diaphragm was torn in five cases. Three had lesions of the heart and/or pericardium and one patient had a tracheal lesion. Closed pleural drainage was the most commonly used treatment. Thoracotomy was performed in 10 of the 93 patients. The mortality rate in the series (10%) agreed with findings from other, similar studies.
    Scandinavian Cardiovascular Journal 07/2009; 20(1).
  • [Show abstract] [Hide abstract]
    ABSTRACT: Pulmonary vein blood flow in mitral valve disease was studied peroperatively in 10 patients undergoing valve replacement. Flow was recorded using a Nycotron electromagnetic flowmeter with a cuff type probe on the right upper pulmonary vein. Pressures in the left atrium and ventricle were recorded simultaneously. the recordings were made both before cannulation for extracorporeal circulation and after mitral valve replacement. the flow curves had a pulsatile pattern and reflected the pressure events in the left atrium. Forward flow reached maximum during ventricular diastole and was reversed during ventricular systole. Maximum retrograde flow coincided with a peak of the left atrial v-wave. With a few exceptions, there was good agreement between the degree of pulmonary vein retrograde flow and grade of mitral insufficiency at left ventricular angiography. After valve replacement, no retrograde pulmonary vein flow was observed. in the majority of patients the v-wave in the left atrium was markedly reduced by surgery. the generation and the relationship of the left atrial v-wave and the retrograde pulmonary vein flow is discussed. It is concluded that the method described may be useful as a reference method when evaluating the degree of mitral insufficiency. It is a valuable tool for the analysis of the haemodynamic events in the left atrium and the pulmonary veins in heart disease.
    Scandinavian Cardiovascular Journal 07/2009; 9(1).
  • [Show abstract] [Hide abstract]
    ABSTRACT: Furiher to previous reports in the literature on 30 cases of thymolipoma, one further such case is clinically and histopathologically described. A tumour weighing HOOg was was incidentally discovered in an otherwise healthy man, 20 years old, whose X-ray examination suggested an enlarged heart. This benign, rare mediastinal tumour is usually asymptomatic or causes mechanical compression of mediastinal organs. Histologically, there are islets and strands of thymic tissue intermingled with mature fat cells.
    Scandinavian Cardiovascular Journal 07/2009; 2(2).
  • [Show abstract] [Hide abstract]
    ABSTRACT: A case of aortic coarctation combined with an anomalous right subclavian artery with both subclavian arteries arising distal to the coarctation is described. Bilateral reversion of the blood flow in both vertebrals was demonstrated. The main collaterals between the carotid arteries and the vertebrals were extracranial. The intra-cerebral circulation was unaffected. The patient, a nine-year-old boy, was successfully treated by operation.
    Scandinavian Cardiovascular Journal 07/2009; 4(2).
  • [Show abstract] [Hide abstract]
    ABSTRACT: The ultrastructural changes undergone by collateral arteries during their development were studied in the rabbit after occlusion of the femoral artery. Profound alterations in shape and composition of cytoplasmic components were noted in the endothelial and smooth muscle cells. Signs of high metabolic effort and increased protein synthesis were found in these cells throughout the period of investigation. Early in the development, modified smooth muscle cells made their appearance in the intima, and their possible function is discussed. In the endothelial and smooth muscle cells, as well as in the extracellular space, vacuole-like formations, presumably representing water-containing inclusions expelled from adjacent cells, were noted. In late stages of collateral development there were signs of focal cytoplasmic degeneration in endothelial and smooth muscle cells. Increased pressure and/or flow appear to be responsible for the ultrastructural changes noted in this study. These changes are not specific for collateral arteries, however, but presumably reflect a common reaction of arteries to injury.
    Scandinavian Cardiovascular Journal 07/2009; 4(3):243-256.
  • [Show abstract] [Hide abstract]
    ABSTRACT: Collateral development in the lower extremity of the rabbit was studied by arteriographic techniques after occlusion of the femoral artery. Characteristic collateral patterns developed, depending on the level and extent of arterial occlusion. Early after the occlusion some pathways were found to conduct the flow rapidly to the distal stem. In subsequent arteriograms on the same animals these arterial channels were later seen to dominate the collateral circulation, while other pathways seemed to regress. In most cases the definitive appearance of the collateral pattern could be anticipated at an early time after the occlusion. During the development histological study showed a pronounced increase in the smooth muscle mass of the collateral arterial wall, which permitted further dilatation of the vessel. This increase was most pronounced in the intermediate zone of the collateral pathway, but was also clearly evident in the proximal and distal zones. A critical investigation of the arteriographic method of estimating changes in diameter of collateral vessels showed that this method can give no reliable measurements of the changes in the initial stage of development.
    Scandinavian Cardiovascular Journal 07/2009; 5(3):265-274.
  • [Show abstract] [Hide abstract]
    ABSTRACT: Blood flow has been studied with the electromagnetic flowmeter in 22 patients after reconstruction of the leg arteries during the per- and early postoperative periods with implanted flow probes. Sixteen vein bypasses, 5 superficial femoral arteries and 2 common femoral arteries were studied. The average flow after reconstruction was 215 in the vein bypasses, 210 in the superficial femoral artery and 240, respective, 250 in the common femoral artery. The flow increased during the final phase of operation, and on termination the flow was in average 290 ml/min in the bypass 340 ml/min in the superficial femoral artery and 690 and 705 ml/min, respectively, in the common femoral artery. Repeated measurements were made 24, 48 and 72 hours postoperatively and the changes in flow were studied at rest and during various forms of exercise. The flow decreased during the first postoperative hours. From the afternoon of the day of operation to the next day, the flow at rest increased significantly in the bypass cases from 220 to 320 ml/min and remained at this level during the following days. The calf exercises in supine position increased the flow 60 to 85% in average in all the investigated vessels. Heel raising increased the flow 150% in the bypass and the superficial femoral artery and 225% in the common femoral artery. Bicycling with a load of 150 kpm/min increased the flow approximately 100% in the vein bypass and the superficial femoral artery and 260% in the common femoral artery. Some low flow values recorded after reconstruction were corrected with blood transfusion and further surgical intervention. One patient had a flow of only 30 ml/min on the second postoperative day, which increased after correction of an acute attack of atrial fibrillation and a probable state of hypovolaemia.
    Scandinavian Cardiovascular Journal 07/2009; 4(2):159-171.
  • [Show abstract] [Hide abstract]
    ABSTRACT: In an in vitro study, extracorporeal circuits equipped with either a leukocyte-depleting filter (n = 5) or a standard arterial-line filter (n = 5) were perfused for 120 minutes with fresh human whole blood. Leukocyte activation, leukocyte and platelet counts and complement activation were studied. Significant reduction of leukocyte and platelet counts and significant activation of leukocytes and of platelets were found in both groups, but without significant intergroup difference for any parameter after 120 minutes of perfusion. The leukocyte-depleting filters, however, were somewhat more effective in removing leukocytes during the initial 30 minutes of circulation.
    Scandinavian Cardiovascular Journal 07/2009; 31(2):73-77.
  • [Show abstract] [Hide abstract]
    ABSTRACT: The significant risk of cerebral embolism during cardiopulmonary bypass (CPB) makes monitoring of embolic events advisable already when developing new operation and coagulation management strategies for example in CPB animal models. The present study therefore evaluated in a porcine CPB model the feasibility of bilateral epicarotid Doppler signal recording and the quality of manual or automatic emboli detection. A total of 42 recordings (e.g. right carotid artery (n =20), left carotid artery (n =22)) were evaluated. The frequency of emboli counts was comparable for both carotid arteries. Automatic emboli detection, however, found significantly more embolic events per pig than did post-hoc manual off-line analysis of the recordings (172±217 vs. 13±10). None of the brains, however, showed any emboli or infarction area either in cross-examination or in histological evaluation. In conclusion, the present study showed the feasibility of using an epicarotid Doppler device for bilateral emboli detection in a porcine CPB model. Automatic on-line emboli detection, however, reported more embolic events than did post hoc, off-line manual analysis. Possible reasons for this discrepancy are discussed.
    Scandinavian Cardiovascular Journal 07/2009; 41(6):411-415.
  • Scandinavian Cardiovascular Journal 07/2009; 34(1):3-3.
  • Scandinavian Cardiovascular Journal 07/2009; 32(5):315-315.
  • [Show abstract] [Hide abstract]
    ABSTRACT: This retrospective study assesses the early diagnostic potential of a combination of multilead continuous vectorcardiography (VCG) and biochemical markers (myoglobin, troponin-t and CK-mb mass) in patients with chest pain who present with suspected acute myocardial infarction (AMI), but without ST-elevation on resting 12-lead ECG on admission. Within a multicenter study 56 patients admitted for chest pain (<12 h) and with a non-diagnostic 12-lead ECG on admission and a VCG recording were included. Venous blood samples were drawn on admission and the continuous VCG was monitored for 2 h. The results were related to the clinical diagnosis of AMI. Neither the biochemical markers nor VCG alone permitted the diagnosis or exclusion of AMI at admission. However, if either analysis of myoglobin on admission or 2 h of VCG recording were positive, they would have a sensitivity for detection of AMI of 100% and specificity of 69%. In a subset of patients with more than 4 h delay since start of chest pain, CK-mb could replace myoglobin and give a sensitivity of 100% and a specificity of 81%. Determination of myoglobin or CK-mb at admission and VCG monitoring for 2 h can reliably confirm or exclude AMI within 2 h. This combination seems useful for early stratifications of patients in chest pain or coronary care units.
    Scandinavian Cardiovascular Journal 07/2009; 34(2):172-177.
  • [Show abstract] [Hide abstract]
    ABSTRACT: The aim of this nationwide case-control study was to study the epidemiology and identify risk factors of deep sternal wound infections (DSWI) in Iceland. Between 1997-2004, 1 650 adults underwent open cardiac surgery in Iceland. For every infected patient four control subjects were chosen (n =163), matched for time of operation. The groups were compared by multivariable logistic regression analysis. Forty one patients (2.5%) developed DSWI, most often following CABG (76%). The most common pathogens were Staphylococcus aureus (39%) and coagulase-negative staphylococci (24%). All except two patients underwent debridement and rewiring of the sternum. Length of hospital stay was significantly longer in the DSWI group with a trend for increased hospital mortality and significantly greater 1-year mortality (17% vs. 5%, p =0.02). History of stroke (OR 5.12), peripheral arterial disease (OR 5), corticosteroid use (OR 4.25), smoking (OR 3.66) and re-operation for bleeding (OR 4.66) were the strongest independent predictors for DSWI. Incidence of DSWI in Iceland (2.5%) is comparable to other recently published studies, with similar risk factors and significantly reduced survival at one year following the infection.
    Scandinavian Cardiovascular Journal 07/2008; 42(3):208-13.